Jakob R. Winther
Professor
Biomolecular Sciences
Ole Maaløes Vej 5
2200 København N.
- 2023
- Published
Global analysis of multi-mutants to improve protein function
Johansson, Kristoffer Enøe, Lindorff-Larsen, Kresten & Winther, Jakob R., 2023, In: Journal of Molecular Biology. 435, 8, 15 p., 168034.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Co-evolution of drug resistance and broadened substrate recognition in HIV protease variants isolated from an Escherichia coli genetic selection system
Koivisto, J. M., Poulsen, N. R., Larsen, B. S., Weibull, M. G. M., Stein, Amelie, Doro, F., Winther, Jakob R., Lindorff-Larsen, Kresten & Willemoës, Martin, 2022, In: The Biochemical journal. 479, 4, p. 479-501Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Engineering Bifidobacterium longum Endo-α-N-acetylgalactosaminidase for Neu5Acα2-3Ga1β1-3Ga1NAc reactivity on Fetuin
Hansen, D. K., Hansen, A. L., Koivisto, J. M., Shuoker, B., Abou Hachem, M., Winther, Jakob R. & Willemoës, Martin, 2022, In: Archives of Biochemistry and Biophysics. 725, 8 p., 109280.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increasing protein stability by inferring substitution effects from high-throughput experiments
Norrild, R. K., Johansson, Kristoffer Enøe, O'Shea, Charlotte, Morth, J. P., Lindorff-Larsen, Kresten & Winther, Jakob R., 2022, In: Cell Reports Methods. 2, 11, 11 p., 100333.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The functional role of the autolysis loop in the regulation of factor X upon hemostatic response
Bonde, A. C., Lund, J., Hansen, J. J., Winther, Jakob R., Nielsen, P. F., Zahn, S., Tiainen, P., Olsen, O. H., Petersen, H. H. & Rose Bjelke, J., 2022, In: Journal of Thrombosis and Haemostasis. 20, 3, p. 589-599 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
VM i molekylære puslespil
Abildgaard, A. B., Winther, Jakob R., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 16 Apr 2021, In: Weekendavisen: Ideer. 15, p. 11Research output: Contribution to journal › Contribution to newspaper - Feature article › Communication
- Published
Molekylære stavefejl
Abildgaard, A. B., Winther, Jakob R., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 28 Jan 2021, In: Weekendavisen, Ideer.Research output: Contribution to journal › Contribution to newspaper - Feature article › Communication
- Published
Charge Engineering Reveals the Roles of Ionizable Side Chains in Electrospray Ionization Mass Spectrometry
Abramsson, M. L., Sahin, C., Hopper, J. T. S., Branca, R. M. M., Danielsson, J., Xu, M., Chandler, S. A., Österlund, N., Ilag, L. L., Leppert, A., Costeira-Paulo, J., Lang, L., Teilum, K., Laganowsky, A., Benesch, J. L. P., Oliveberg, M., Robinson, C. V., Marklund, E. G., Allison, T. M., Winther, J. R. & 1 others, , 2021, In: JACS Au. 1, 12, p. 2385-2393 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Charge Interactions in a Highly Charge-Depleted Protein
Hervø-Hansen, S., Højgaard, C., Johansson, Kristoffer Enøe, Wang, Yong, Wahni, K., Young, D., Messens, J., Teilum, Kaare, Lindorff-Larsen, Kresten & Winther, Jakob R., 2021, In: Journal of the American Chemical Society. 143, 6, p. 2500-2508 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Computational and Experimental Assessment of Backbone Templates for Computational Redesign of the Thioredoxin Fold
Marin, Frederikke Isa, Johansson, Kristoffer Enøe, O'Shea, Charlotte, Lindorff-Larsen, Kresten & Winther, Jakob R., 2021, In: The Journal of Physical Chemistry B. 125, 40, p. 11141-11149Research output: Contribution to journal › Journal article › Research › peer-review
- Published
- Published
Flash properties of Gaussia luciferase are the result of covalent inhibition after a limited number of cycles
Dijkema, F. M., Nordentoft, M. K., Didriksen, A. K., Corneliussen, A. S., Willemoës, Martin & Winther, Jakob R., 2021, In: Protein Science. 30, 3, p. 638-649 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rational Protein Engineering to Increase the Activity and Stability of IsPETase Using the PROSS Algorithm
Rennison, A., Winther, Jakob R. & Varrone, C., 2021, In: Polymers. 13, 22, 11 p., 3884.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Substitutional landscape of a split fluorescent protein fragment using high-density peptide microarrays
Antonescu, O. N., Rasmussen, A., Damm, N. A. M., Heidemann, Ditte Fogh, Popov, R., Nesterov-Mueller, A., Johansson, Kristoffer Enøe & Winther, Jakob R., 2021, In: PLoS ONE. 16, 2, 17 p., e0241461.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Mutations in a Single Signaling Pathway Allow Cell Growth in Heavy Water
Kampmeyer, Caroline, Johansen, Jens Vilstrup, Holmberg, Christian, Karlson, M., Andersen, Sarah Gersing, Nunes Bordallo, Heloisa, Kragelund, Birthe Brandt, Lerche, M. H., Jourdain, I., Winther, Jakob R. & Hartmann-Petersen, Rasmus, 2020, In: A C S Synthetic Biology. 9, 4, p. 733-748 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Improving folding properties of computationally designed proteins
Bjerre, B., Nissen, J., Madsen, M., Kamarauskaite, J., Norrild, R. K., Holm, Peter Christoffer, Nordentoft, M. K., O'Shea, Charlotte, Willemoës, Martin, Johansson, Kristoffer Enøe & Winther, Jakob R., 13 Dec 2019, In: Protein Engineering Design and Selection (Print). 32, 3, p. 145-151 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Shining light on split fluorescent protein fitness landscapes using peptide array-based deep substitutional scanning
ANTONESCU, O., Johansson, Kristoffer Enøe & Winther, Jakob R., 30 Jun 2019.Research output: Contribution to conference › Poster › Research › peer-review
- Published
Pulmonary effects of nanofibrillated celluloses in mice suggest that carboxylation lowers the inflammatory and acute phase responses
Hadrup, N., Knudsen, K. B., Berthing, T., Wolff, H., Bengtson, S., Kofoed, Christian, Espersen, R., Højgaard, C., Winther, Jakob R., Willemoës, Martin, Wedin, I., Nuopponen, M., Alenius, H., Norppa, H., Wallin, H. & Vogel, U., 2019, In: Environmental Toxicology and Pharmacology. 66, p. 116-125 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Steady state kinetic analysis of O-linked GalNAc glycan release catalyzed by endo-α-N-acetylgalactosaminidase
Hansen, D. K., Winther, Jakob R. & Willemoës, Martin, 2019, In: Carbohydrate Research. 480, p. 54-60Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Comprehensive mapping of GFP structure-function relationship using high-density peptide arrays
Antonescu, O., Johansson, Kristoffer Enøe & Winther, Jakob R., 10 Jul 2018.Research output: Contribution to conference › Poster › Research › peer-review
- Published
A Robust Proton Flux (pHlux) Assay for Studying the Function and Inhibition of the Influenza A M2 Proton Channel
Santner, P., Martins, J. M. D. S., Laursen, J. S., Behrendt, L., Riber, Leise, Olsen, Christian Adam, Arkin, I. T., Winther, Jakob R., Willemoës, Martin & Lindorff-Larsen, Kresten, 2018, In: Biochemistry. 57, 41, p. 5949-5956Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Can a Charged Surfactant Unfold an Uncharged Protein?
Højgaard, C., Sørensen, H. V., Pedersen, J. S., Winther, Jakob R. & Otzen, D. E., 2018, In: Biophysical Journal. 115, 11, p. 2081-2086 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Editorial overview: A perspective on protein evolution
Hoecker, B. & Winther, Jakob R., 2018, In: Current Opinion in Structural Biology. 48, p. viii-ix 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Nanofibrillated cellulose causes acute pulmonary inflammation that subsides within a month
Ilves, M., Vilske, S., Aimonen, K., Lindberg, H. K., Pesonen, S., Wedin, I., Nuopponen, M., Vanhala, E., Højgaard, C., Winther, Jakob R., Willemoës, Martin, Vogel, U., Wolff, H., Norppa, H., Savolainen, K. & Alenius, H., 2018, In: Nanotoxicology. 12, 7, p. 729-746 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein evolution: Hacking an enzyme
Johansson, Kristoffer Enøe & Winther, Jakob R., 2018, In: Nature Chemical Biology. 14, 3, p. 202-204 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
ID: 5143
Most downloads
-
1608
downloads
In Silico prediction of mutant HIV-1 proteases cleaving a target sequence
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
267
downloads
A soluble, folded protein without charged amino acid residues
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
226
downloads
Computational redesign of thioredoxin is hypersensitive towards minor conformational changes in the backbone template
Research output: Contribution to journal › Journal article › Research › peer-review
Published