Søren Tvorup Christensen

Søren Tvorup Christensen

Professor

ORCID: 0000-0001-5004-304X

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  1. Published

    Mutation of the planar cell polarity gene VANGL1 in adolescent idiopathic scoliosis

    Andersen, M. R., Farooq, M., Rasmussen, K. K., Kjaer, K. W., Simony, A., Christensen, Søren Tvorup & Larsen, Lars Allan, 2017, In: Spine. 42, 12, p. E702–E707 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Cellular signalling by primary cilia in development, organ function and disease

    Anvarian, Zeinab, Mykytyn, K., Mukhopadhyay, S., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2019, In: Nature Reviews Nephrology. 15, p. 199-219

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    Immunoflourescence and mRNA analysis of human embryonic stem cells (hESCs) grown under feeder-free conditions

    Awan, A., Oliveri, R. S., Jensen, P. L., Christensen, Søren Tvorup & tcg964, tcg964, 1 Jan 2010, In: Methods in Molecular Biology. 584, p. 195-210 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Human RTEL1 associates with Poldip3 to facilitate responses to replication stress and R-loop resolution

    Björkman, A., Johansen, S. L., Lin, L., Schertzer, M., Kanellis, D. C., Katsori, A., Christensen, Søren Tvorup, Luo, Y., Andersen, J. S., Elsässer, S. J., Londono-Vallejo, A., Bartek, J. & Schou, K. B., 2020, In: Genes & Development. 34, 15-16, p. 1065-1074 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    CGRP-dependent signalling pathways involved in mouse models of GTN- cilostazol- and levcromakalim-induced migraine

    Christensen, S. L., Rasmussen, R. H., Ernstsen, C., La Cour, S., David, A., Chaker, J., Haanes, K. A., Christensen, Søren Tvorup, Olesen, Jes & Kristensen, D. M., 2021, In: Cephalalgia. 41, 14, p. 1413-1426 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Smooth muscle ATP-sensitive potassium channels mediate migraine-relevant hypersensitivity in mouse models

    Christensen, S. L., Rasmussen, Rikke Holm, Cour, S. L., Ernstsen, C., Hansen, Thomas Folkmann, Kogelman, L. J. A., Lauritzen, S. P., Guzaite, G., Styrishave, Bjarne, Janfelt, Christian, Christensen, Søren Tvorup, Aziz, Q., Tinker, A., Jansen-Olesen, I., Olesen, Jes & Kristensen, D. M., 2022, In: Cephalalgia. 42, 2, p. 93-107

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Chapter 10 the primary cilium coordinates signaling pathways in cell cycle control and migration during development and tissue repair

    Christensen, Søren Tvorup, Pedersen, Stine Helene Falsig, Satir, P., Veland, I. R. & Schneider, L., 2008, In: Current Topics in Developmental Biology. 85, p. 261-301 40 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Sensory cilia and integration of signal transduction in human health and disease.

    Christensen, Søren Tvorup, Pedersen, Lotte Bang, Schneider, L. & Satir, P., 2007, In: Traffic - International Journal of Intracellular Transport. 8, 2, p. 97-109 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Insulin receptor-like proteins in tetrahymena thermophila ciliary membranes

    Christensen, Søren Tvorup, Guerra, C. F., Awan, A., Wheatley, D. N. & Satir, P., 2003, In: Curr. Biol.. 13, p. R50-52

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Receptor tyrosine phosphorylation in cilia: a pathway of growth control?

    Christensen, Søren Tvorup, Schneider, L., Teilmann, S. C., Awan, A., Guerra, C. F., Hoffmann, E. K. & Satir, P., 2004, In: Molecular Biology of the Cell. vol. 15, p. 359a

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Evolution of protein kinases: Identification of tyrosine kinases in sensory cilia of tetrahymena

    Christensen, Søren Tvorup, Guerra, C. F., Awan, A., Valentin, T., Wheatley, D. N., Gammeltoft, S. & Satir, P., 2003, In: Molecular Biology of the Cell. vol. 14, p. 433a

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The primary cilium is a sensory organelle that regulates growth control and tissue homeostasis

    Christensen, Søren Tvorup, Schneider, L., Clement, C. A., Pazour, G., Hoffmann, E. K. & Satir, P., 2006, In: The FASEB Journal. 20, p. A437

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Insulin produces a biphasic response in Tetrahymena thermophila by stimulating cell survival and activating proliferation in two separate concentration intervals

    Christensen, Søren Tvorup, Quie, H., Kemp, K. & Rasmussen, L., 1996, In: Cell Biology International. 20, 6, p. 437-44 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Primary cilia and coordination of receptor tyrosine kinase (RTK) and transforming growth factor β (TGF-β) signaling

    Christensen, Søren Tvorup, Morthorst, Stine Kjær, Mogensen, J. B. & Pedersen, Lotte Bang, 2017, In: Cold Spring Harbor Perspectives in Biology. 9, 6, 18 p., a028167.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    High expression of the taurine transporter TauT in primary cilia of NIH3T3 fibroblasts

    Christensen, Søren Tvorup, Voss, J. W., Teilmann, S. C. & Lambert, Ian Henry, 2005, In: Cell Biology International. 29, 5, p. 347-351

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Primary cilia and coordination of receptor tyrosine kinase (RTK) signaling

    Christensen, Søren Tvorup, Clement, C. A., Satir, P. & Pedersen, Lotte Bang, 2012, In: Journal of Pathology. 226, 2, p. 172-184 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Mechanisms controlling death, survival and proliferation in a model unicellular eukaryote Tetrahymena thermophila

    Christensen, Søren Tvorup, Wheatley, D. N., Rasmussen, M. I. & Rasmussen, L., 1995, In: Cell Death and Differentiation. 2, 4, p. 301-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Cell signaling. A ciliary signaling switch

    Christensen, Søren Tvorup & Ott, C. M., 2007, In: Science. 317, 5836, p. 330-1 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Cell death, survival and proliferation in Tetrahymena thermophila. Effects of insulin, sodium nitroprusside, 8-Bromo cyclic GMP, NG-methyl-L-arginine and methylene blue

    Christensen, Søren Tvorup, Rasmussen, L., Kemp, K. & Quie, H., 1996, In: Cell Biology International. 20, 10, p. 653-66 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. A regulatory light chain of ciliary outer arm dynein in Tetrahymena thermophila

    Christensen, Søren Tvorup, Guerra, C., Wada, Y., Valentin, T., Angeletti, R. H., Satir, P. & Hamasaki, T., 2001, In: Journal of Biological Chemistry. 276, 23, p. 20048-54 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Analysis of primary cilia in directional cell migration in fibroblasts

    Christensen, Søren Tvorup, Veland, I., Schwab, A., Cammer, M. & Satir, P., 2013, In: Methods in Enzymology. 525, p. 45-58 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Insulin rescues the unicellular eukaryote Tetrahymena from dying in a complete, synthetic nutrient medium

    Christensen, Søren Tvorup, 1993, In: Cell Biology International. 17, 9, p. 833-7 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Signaling in unicellular eukaryotes

    Christensen, Søren Tvorup, Leick, V. R. & Rasmussen, L., 1997, In: International Review of Cytology. 177, p. 181-253

    Research output: Contribution to journal › Journal article › Research

  24. Published

    The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation

    Clement, C. A., Kristensen, S. G., Møllgård, Kjeld, Pazour, G. J., Yoder, B. K., Larsen, Lars Allan & Christensen, Søren Tvorup, 2009, In: Journal of Cell Science. 122, Pt 17, p. 3070-82 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    PDGF-AA Induced Activation of the Mitogenic Erk1/2-Mek1/2 Pathway Localizes to the Primary Cilium and the Ciliary Basal Body in NIH3T3 Fibroblasts

    Clement, C. A., Schneider, L., Teilman, S. C., Satir, P. & Christensen, Søren Tvorup, 2005, In: The FASEB Journal. Suppl., p. 650 a

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    TGF-β Signaling Is Associated with Endocytosis at the Pocket Region of the Primary Cilium

    Clement, C. A., Ajbro, K. D., Koefoed, K., Vestergaard, M. L., Veland, I. R., Perestrello Ramos H de Jesus, M., Pedersen, Lotte Bang, Benmerah, A., tcg964, tcg964, Larsen, Lars Allan & Christensen, Søren Tvorup, 2013, In: Cell Reports. 3, 6, p. 1806-1814 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Using Nucleofection of siRNA Constructs for Knockdown of Primary Cilia in P19.CL6 Cancer Stem Cell Differentiation into Cardiomyocytes

    Clement, C. A., Larsen, Lars Allan & Christensen, Søren Tvorup, 2009, Methods in Cell Biology. Sloboda, R. D. (ed.). Academic Press, Vol. 94. p. 181-197

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  28. Published

    PDGFR alpha signaling in the primary cilium regulates NHE1-dependent fibroblast migration via coordinated differential activity of MEK1/2-ERK1/2-p90(RSK) and AKT signaling pathways

    Clement, Ditte Lynge, Mally, S., Stock, C., Lethan, M., Satir, P., Schwab, A., Pedersen, Stine Helene Falsig & Christensen, Søren Tvorup, 2013, In: Journal of Cell Science. 126, 4, p. 953-965 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Primary cilia and aberrant cell signaling in epithelial ovarian cancer

    Egeberg, D. L., Lethan, M., Manguso, R., Schneider, L., Awan, A., Jørgensen, T. S., Byskov, A. G., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2012, In: Cilia. 1, 15, 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    RRP7A links primary microcephaly to dysfunction of ribosome biogenesis, resorption of primary cilia, and neurogenesis

    Farooq, M., Lindbæk, L., Krogh, N., Doganli, C., Keller, C., Mönnich, M., Gonçalves, A. B., Sakthivel, S., Mang, Y., Fatima, A., Andersen, V. S., Hussain, M. S., Eiberg, H., Hansen, L., Kjaer, K. W., Gopalakrishnan, J., Pedersen, L. B., Møllgård, K., Nielsen, H., Baig, S. M. & 3 others, Tommerup, Niels, Christensen, Søren Tvorup & Larsen, Lars Allan, 2020, In: Nature Communications. 11, 16 p., 5816.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Physiological studies on the effect of Ca2+ on the duration of the lag phase of Saccharomyces cerevisiae

    Friis, J., Christensen, Søren Tvorup, Szablewski, L., Schousboe, P. & Rasmussen, L., 1994, In: FEMS Microbiology Letters. 123, 1-2, p. 33-6 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Cell shrinkage as a signal to apoptosis in NIH 3T3 fibroblasts.

    Friis, M. B., Friborg, C. R., Schneider, L., Nielsen, M., Lambert, Ian Henry, Christensen, Søren Tvorup & Hoffmann, E. K., 2005, In: Journal of Physiology. 567, 2, p. 427-43 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Comparative Proteome Bioinformatics: Identification of Phosphotyrosine Signaling Proteins in the Unicellular Protozoan Ciliate Tetrahymena

    Gammeltoft, S., Christensen, Søren Tvorup, Joachimiak, M., Hill, E., Guerra, C. F. & Satir, P., 2005, In: The FASEB Journal. Suppl., p. 785 a

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Compounds stimulating growth and multiplication in ciliates. Do also free-living cells release growth factors?

    Ghiladi, M., Christensen, Søren Tvorup, Schousboe, P. & Rasmussen, L., 1992, In: Die Naturwissenschaften. 79, 5, p. 234-5 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels

    Gonçalves, A. B., Hasselbalch, S. K., Joensen, B. B., Patzke, S., Martens, P., Ohlsen, S. K., Quinodoz, M., Nikopoulos, K., Suleiman, R., Jeppesen, M. P. D., Weiss, C., Christensen, Søren Tvorup, Rivolta, C., Andersen, J. S., Farinelli, P. & Pedersen, Lotte Bang, 2021, In: eLife. 10, 34 p., e63731.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Comparison of cultured human cardiomyocyte clusters obtained from embryos/fetuses or derived from human embryonic stem cells

    Grubb, Søren, Vestergaard, M. L., Andersen, A. S., Rasmussen, K. K., Mamsen, L., Tuckute, G., Grunnet-Lauridsen, K., Møllgård, Kjeld, Ernst, E., Christensen, Søren Tvorup, Callø, Kirstine & tcg964, tcg964, 2019, In: Stem Cells and Development. 28, 9, p. 608-619

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Tetrahymena cilia - not just oars on a boat

    Guerra, C. F., Christensen, Søren Tvorup, Awan, A., Bell, A., Jabbour, N., Valentin, T. & Satir, P., 2003, In: Molecular Biology of the Cell. vol. 14, p. 434a

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Signaling in Tetrahymena Cilia: Evolution of Ciliary Signaling for Mammalian Growth Control Regulation

    Guerra, C. F., Bell, A. J., Awan, A., Christensen, Søren Tvorup & Satir, P., 2005, In: The FASEB Journal. Suppl., p. 652 a

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Effects of osmotic stress on the activity of receptor tyrosine kinases and MAP kinases in NIH3T3-fibtoblasts

    Hoffmann, E. K., Nielsen, M. & Christensen, Søren Tvorup, 2004, In: Molecular Biology of the Cell. 15, p. 14a

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Proteomic analysis of human blastocoel fluid and blastocyst cells

    Jensen, P., Beck, H. C., Petersen, J., Hreinsson, J., Wånggren, K., Laursen, S. B., Sørensen, P. D., Christensen, Søren Tvorup & tcg964, tcg964, 2013, In: Stem Cells and Development. 22, 7, p. 1126-1135 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Proteomic analysis of bovine blastocoel fluid and blastocyst cells

    Jensen, P. L., Grøndahl, M. L., Beck, H. C., Petersen, J., Stroebech, L., Christensen, Søren Tvorup & tcg964, tcg964, 2014, In: Systems Biology in Reproductive Medicine. 60, 3, p. 127-135 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Editorial: Signaling by primary cilia in development and disease

    Kim, S. E., Nechipurenko, I. & Christensen, Søren Tvorup, 2023, In: Frontiers in Cell and Developmental Biology. 11, 3 p., 1186367.

    Research output: Contribution to journal › Editorial › Research › peer-review

  43. Published

    Human embryonic stem cells in culture possess primary cilia with hedgehog signaling machinery.

    Kiprilov, E. N., Awan, A., Desprat, R., Velho, M., Clement, C. A., Byskov, A. G., tcg964, tcg964, Satir, P., Bouhassira, E. E., Christensen, Søren Tvorup & Hirsch, R. E., 2008, In: Journal of Cell Biology. 180, 5, p. 897-904 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Cilia and coordination of signaling networks during heart development

    Koefoed, K., Veland, I. R., Pedersen, Lotte Bang, Larsen, Lars Allan & Christensen, Søren Tvorup, 2014, In: Organogenesis. 10, 1, p. 108-125 18 p.

    Research output: Contribution to journal › Review › Research › peer-review

  45. Published

    Challenges for the sustainability of university-run biobanks

    Kongsholm, Nana Cecilie Halmsted, Christensen, Søren Tvorup, Herrmann, Janne Rothmar, Larsen, Lars Allan, Minssen, Timo, Pedersen, Lotte Bang, Rajam, N., Tommerup, Niels, Tupasela, A. M. & Schovsbo, Jens Hemmingsen, 2018, In: Biopreservation and Biobanking. 16, 4, p. 312-321 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    TGFβ1-induced recruitment of human bone mesenchymal stem cells is mediated by the primary cilium in a SMAD3-dependent manner

    Labour, M., Riffault, M., Christensen, Søren Tvorup & Hoey, D. A., 2016, In: Scientific Reports. 6, 13 p., 35542.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Hot spots of N2O emission move with the seasonally mobile oxic-anoxic interface in drained organic soils

    Lee, A. J., Winther, M. N., Priemé, Anders, Blunier, Thomas & Christensen, Søren Tvorup, 1 Dec 2017, In: Soil Biology & Biochemistry. 115, p. 178-186 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Coordination of TGFβ/BMP signaling is associated with the primary cilium

    Lindbæk, L., Warzecha, C. B., Koefoed, K., Mogensen, J. B., Schmid, F., Pedersen, Lotte Bang, Larsen, Lars Allan & Christensen, Søren Tvorup, 2015, In: Cilia. 4, Suppl. 1, 1 p., P17.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  49. Published

    Glucocorticoids exert context-dependent effects on cells of the joint in vitro

    Madsen, S. H., Andreassen, K. V., Christensen, Søren Tvorup, Karsdal, M. A., Sverdrup, F. M., Bay-Jensen, A. & Henriksen, K., 2011, In: Steroids. 76, 13, p. 1474-82 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Characterization of an ex vivo femoral head model assessed by markers of bone and cartilage turnover

    Madsen, S. H., Goettrup, A. S., Thomsen, G., Christensen, Søren Tvorup, Schultz, N., Henriksen, K., Bay-Jensen, A. & Karsdal, M. A., 2011, In: Cartilage. 2, 3, p. 265-278 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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