β Cell Dysfunction in Type 2 Diabetes: Drained of Energy?
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β Cell Dysfunction in Type 2 Diabetes : Drained of Energy? / Knudsen, Jakob G.; Rorsman, Patrik.
I: Cell Metabolism, Bind 29, Nr. 1, 2019, s. 1-2.Publikation: Bidrag til tidsskrift › Leder › Forskning › fagfællebedømt
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TY - JOUR
T1 - β Cell Dysfunction in Type 2 Diabetes
T2 - Drained of Energy?
AU - Knudsen, Jakob G.
AU - Rorsman, Patrik
N1 - Copyright © 2018 Elsevier Inc. All rights reserved.
PY - 2019
Y1 - 2019
N2 - Type 2 diabetes is a progressive disorder, but exactly how the progression occurs remains unknown. In this issue of Cell Metabolism, Zhang et al. (2019) present evidence that diabetes, via hyperglycemia, leads to aberrant insertion of a mitochondrial ion channel in the plasma membrane, rendering it leaky to key intracellular signaling molecules with resultant suppression of insulin secretion.
AB - Type 2 diabetes is a progressive disorder, but exactly how the progression occurs remains unknown. In this issue of Cell Metabolism, Zhang et al. (2019) present evidence that diabetes, via hyperglycemia, leads to aberrant insertion of a mitochondrial ion channel in the plasma membrane, rendering it leaky to key intracellular signaling molecules with resultant suppression of insulin secretion.
U2 - 10.1016/j.cmet.2018.12.015
DO - 10.1016/j.cmet.2018.12.015
M3 - Editorial
C2 - 30625305
VL - 29
SP - 1
EP - 2
JO - Cell Metabolism
JF - Cell Metabolism
SN - 1550-4131
IS - 1
ER -
ID: 227695071