Genome of the Tasmanian tiger provides insights into the evolution and demography of an extinct marsupial carnivore

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

Genome of the Tasmanian tiger provides insights into the evolution and demography of an extinct marsupial carnivore. / Feigin, Charles Y.; Newton, Axel H.; Doronina, Liliya; Schmitz, Jürgen; Hipsley, Christy A.; Mitchell, Kieren J.; Gower, Graham; Llamas, Bastien; Soubrier, Julien; Heider, Thomas N.; Menzies, Brandon R.; Cooper, Alan; O'Neill, Rachel J.; Pask, Andrew J.

I: Nature Ecology & Evolution, Bind 2, 2018, s. 182-192.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Feigin, CY, Newton, AH, Doronina, L, Schmitz, J, Hipsley, CA, Mitchell, KJ, Gower, G, Llamas, B, Soubrier, J, Heider, TN, Menzies, BR, Cooper, A, O'Neill, RJ & Pask, AJ 2018, 'Genome of the Tasmanian tiger provides insights into the evolution and demography of an extinct marsupial carnivore', Nature Ecology & Evolution, bind 2, s. 182-192. https://doi.org/10.1038/s41559-017-0417-y

APA

Feigin, C. Y., Newton, A. H., Doronina, L., Schmitz, J., Hipsley, C. A., Mitchell, K. J., Gower, G., Llamas, B., Soubrier, J., Heider, T. N., Menzies, B. R., Cooper, A., O'Neill, R. J., & Pask, A. J. (2018). Genome of the Tasmanian tiger provides insights into the evolution and demography of an extinct marsupial carnivore. Nature Ecology & Evolution, 2, 182-192. https://doi.org/10.1038/s41559-017-0417-y

Vancouver

Feigin CY, Newton AH, Doronina L, Schmitz J, Hipsley CA, Mitchell KJ o.a. Genome of the Tasmanian tiger provides insights into the evolution and demography of an extinct marsupial carnivore. Nature Ecology & Evolution. 2018;2:182-192. https://doi.org/10.1038/s41559-017-0417-y

Author

Feigin, Charles Y. ; Newton, Axel H. ; Doronina, Liliya ; Schmitz, Jürgen ; Hipsley, Christy A. ; Mitchell, Kieren J. ; Gower, Graham ; Llamas, Bastien ; Soubrier, Julien ; Heider, Thomas N. ; Menzies, Brandon R. ; Cooper, Alan ; O'Neill, Rachel J. ; Pask, Andrew J. / Genome of the Tasmanian tiger provides insights into the evolution and demography of an extinct marsupial carnivore. I: Nature Ecology & Evolution. 2018 ; Bind 2. s. 182-192.

Bibtex

@article{a81fe714bb504762a1911487421eb579,
title = "Genome of the Tasmanian tiger provides insights into the evolution and demography of an extinct marsupial carnivore",
abstract = "The Tasmanian tiger or thylacine (Thylacinus cynocephalus) was the largest carnivorous Australian marsupial to survive into the modern era. Despite last sharing a common ancestor with the eutherian canids ~160 million years ago, their phenotypic resemblance is considered the most striking example of convergent evolution in mammals. The last known thylacine died in captivity in 1936 and many aspects of the evolutionary history of this unique marsupial apex predator remain unknown. Here we have sequenced the genome of a preserved thylacine pouch young specimen to clarify the phylogenetic position of the thylacine within the carnivorous marsupials, reconstruct its historical demography and examine the genetic basis of its convergence with canids. Retroposon insertion patterns placed the thylacine as the basal lineage in Dasyuromorphia and suggest incomplete lineage sorting in early dasyuromorphs. Demographic analysis indicated a long-term decline in genetic diversity starting well before the arrival of humans in Australia. In spite of their extraordinary phenotypic convergence, comparative genomic analyses demonstrated that amino acid homoplasies between the thylacine and canids are largely consistent with neutral evolution. Furthermore, the genes and pathways targeted by positive selection differ markedly between these species. Together, these findings support models of adaptive convergence driven primarily by cis-regulatory evolution.",
author = "Feigin, {Charles Y.} and Newton, {Axel H.} and Liliya Doronina and J{\"u}rgen Schmitz and Hipsley, {Christy A.} and Mitchell, {Kieren J.} and Graham Gower and Bastien Llamas and Julien Soubrier and Heider, {Thomas N.} and Menzies, {Brandon R.} and Alan Cooper and O'Neill, {Rachel J.} and Pask, {Andrew J.}",
year = "2018",
doi = "10.1038/s41559-017-0417-y",
language = "English",
volume = "2",
pages = "182--192",
journal = "Nature Ecology & Evolution",
issn = "2397-334X",
publisher = "nature publishing group",

}

RIS

TY - JOUR

T1 - Genome of the Tasmanian tiger provides insights into the evolution and demography of an extinct marsupial carnivore

AU - Feigin, Charles Y.

AU - Newton, Axel H.

AU - Doronina, Liliya

AU - Schmitz, Jürgen

AU - Hipsley, Christy A.

AU - Mitchell, Kieren J.

AU - Gower, Graham

AU - Llamas, Bastien

AU - Soubrier, Julien

AU - Heider, Thomas N.

AU - Menzies, Brandon R.

AU - Cooper, Alan

AU - O'Neill, Rachel J.

AU - Pask, Andrew J.

PY - 2018

Y1 - 2018

N2 - The Tasmanian tiger or thylacine (Thylacinus cynocephalus) was the largest carnivorous Australian marsupial to survive into the modern era. Despite last sharing a common ancestor with the eutherian canids ~160 million years ago, their phenotypic resemblance is considered the most striking example of convergent evolution in mammals. The last known thylacine died in captivity in 1936 and many aspects of the evolutionary history of this unique marsupial apex predator remain unknown. Here we have sequenced the genome of a preserved thylacine pouch young specimen to clarify the phylogenetic position of the thylacine within the carnivorous marsupials, reconstruct its historical demography and examine the genetic basis of its convergence with canids. Retroposon insertion patterns placed the thylacine as the basal lineage in Dasyuromorphia and suggest incomplete lineage sorting in early dasyuromorphs. Demographic analysis indicated a long-term decline in genetic diversity starting well before the arrival of humans in Australia. In spite of their extraordinary phenotypic convergence, comparative genomic analyses demonstrated that amino acid homoplasies between the thylacine and canids are largely consistent with neutral evolution. Furthermore, the genes and pathways targeted by positive selection differ markedly between these species. Together, these findings support models of adaptive convergence driven primarily by cis-regulatory evolution.

AB - The Tasmanian tiger or thylacine (Thylacinus cynocephalus) was the largest carnivorous Australian marsupial to survive into the modern era. Despite last sharing a common ancestor with the eutherian canids ~160 million years ago, their phenotypic resemblance is considered the most striking example of convergent evolution in mammals. The last known thylacine died in captivity in 1936 and many aspects of the evolutionary history of this unique marsupial apex predator remain unknown. Here we have sequenced the genome of a preserved thylacine pouch young specimen to clarify the phylogenetic position of the thylacine within the carnivorous marsupials, reconstruct its historical demography and examine the genetic basis of its convergence with canids. Retroposon insertion patterns placed the thylacine as the basal lineage in Dasyuromorphia and suggest incomplete lineage sorting in early dasyuromorphs. Demographic analysis indicated a long-term decline in genetic diversity starting well before the arrival of humans in Australia. In spite of their extraordinary phenotypic convergence, comparative genomic analyses demonstrated that amino acid homoplasies between the thylacine and canids are largely consistent with neutral evolution. Furthermore, the genes and pathways targeted by positive selection differ markedly between these species. Together, these findings support models of adaptive convergence driven primarily by cis-regulatory evolution.

U2 - 10.1038/s41559-017-0417-y

DO - 10.1038/s41559-017-0417-y

M3 - Journal article

C2 - 29230027

AN - SCOPUS:85037711664

VL - 2

SP - 182

EP - 192

JO - Nature Ecology & Evolution

JF - Nature Ecology & Evolution

SN - 2397-334X

ER -

ID: 255688515