Studies of the association of the GNB3 825C>T polymorphism with components of the metabolic syndrome in white Danes

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Standard

Studies of the association of the GNB3 825C>T polymorphism with components of the metabolic syndrome in white Danes. / Andersen, G.; Overgaard, J.; Albrechtsen, A.; Glümer, C.; Borch-Johnsen, K.; Jørgensen, T.; Hansen, T.; Pedersen, O.

I: Diabetologia, Bind 49, Nr. 1, 2006, s. 75-82.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Andersen, G, Overgaard, J, Albrechtsen, A, Glümer, C, Borch-Johnsen, K, Jørgensen, T, Hansen, T & Pedersen, O 2006, 'Studies of the association of the GNB3 825C>T polymorphism with components of the metabolic syndrome in white Danes', Diabetologia, bind 49, nr. 1, s. 75-82. https://doi.org/10.1007/s00125-005-0049-7

APA

Andersen, G., Overgaard, J., Albrechtsen, A., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Hansen, T., & Pedersen, O. (2006). Studies of the association of the GNB3 825C>T polymorphism with components of the metabolic syndrome in white Danes. Diabetologia, 49(1), 75-82. https://doi.org/10.1007/s00125-005-0049-7

Vancouver

Andersen G, Overgaard J, Albrechtsen A, Glümer C, Borch-Johnsen K, Jørgensen T o.a. Studies of the association of the GNB3 825C>T polymorphism with components of the metabolic syndrome in white Danes. Diabetologia. 2006;49(1):75-82. https://doi.org/10.1007/s00125-005-0049-7

Author

Andersen, G. ; Overgaard, J. ; Albrechtsen, A. ; Glümer, C. ; Borch-Johnsen, K. ; Jørgensen, T. ; Hansen, T. ; Pedersen, O. / Studies of the association of the GNB3 825C>T polymorphism with components of the metabolic syndrome in white Danes. I: Diabetologia. 2006 ; Bind 49, Nr. 1. s. 75-82.

Bibtex

@article{4b96f125fed8455da557ad1f92cd3439,
title = "Studies of the association of the GNB3 825C>T polymorphism with components of the metabolic syndrome in white Danes",
abstract = "The 825C>T polymorphism in the gene encoding the G protein beta3 subunit (GNB3) causes enhanced G protein activation and increased in vitro cell proliferation. This polymorphism is also repeatedly associated with an increased risk of hypertension and has been studied in relation to obesity with divergent results. Only a few association studies have investigated whether this polymorphism is related to type 2 diabetes or the metabolic syndrome. We estimated the impact of the GNB3 825C>T polymorphism in relatively large-scale association studies of common phenotypes of the metabolic syndrome.",
keywords = "Adult, Blood Glucose, Denmark, European Continental Ancestry Group, Fasting, Female, Genotype, Glucose Tolerance Test, Heterotrimeric GTP-Binding Proteins, Humans, Hypertension, Male, Metabolic Syndrome X, Middle Aged, Polymorphism, Single Nucleotide, Risk Factors",
author = "G. Andersen and J. Overgaard and A. Albrechtsen and C. Gl{\"u}mer and K. Borch-Johnsen and T. J{\o}rgensen and T. Hansen and O. Pedersen",
year = "2006",
doi = "10.1007/s00125-005-0049-7",
language = "English",
volume = "49",
pages = "75--82",
journal = "Diabetologia",
issn = "0012-186X",
publisher = "Springer",
number = "1",

}

RIS

TY - JOUR

T1 - Studies of the association of the GNB3 825C>T polymorphism with components of the metabolic syndrome in white Danes

AU - Andersen, G.

AU - Overgaard, J.

AU - Albrechtsen, A.

AU - Glümer, C.

AU - Borch-Johnsen, K.

AU - Jørgensen, T.

AU - Hansen, T.

AU - Pedersen, O.

PY - 2006

Y1 - 2006

N2 - The 825C>T polymorphism in the gene encoding the G protein beta3 subunit (GNB3) causes enhanced G protein activation and increased in vitro cell proliferation. This polymorphism is also repeatedly associated with an increased risk of hypertension and has been studied in relation to obesity with divergent results. Only a few association studies have investigated whether this polymorphism is related to type 2 diabetes or the metabolic syndrome. We estimated the impact of the GNB3 825C>T polymorphism in relatively large-scale association studies of common phenotypes of the metabolic syndrome.

AB - The 825C>T polymorphism in the gene encoding the G protein beta3 subunit (GNB3) causes enhanced G protein activation and increased in vitro cell proliferation. This polymorphism is also repeatedly associated with an increased risk of hypertension and has been studied in relation to obesity with divergent results. Only a few association studies have investigated whether this polymorphism is related to type 2 diabetes or the metabolic syndrome. We estimated the impact of the GNB3 825C>T polymorphism in relatively large-scale association studies of common phenotypes of the metabolic syndrome.

KW - Adult

KW - Blood Glucose

KW - Denmark

KW - European Continental Ancestry Group

KW - Fasting

KW - Female

KW - Genotype

KW - Glucose Tolerance Test

KW - Heterotrimeric GTP-Binding Proteins

KW - Humans

KW - Hypertension

KW - Male

KW - Metabolic Syndrome X

KW - Middle Aged

KW - Polymorphism, Single Nucleotide

KW - Risk Factors

U2 - 10.1007/s00125-005-0049-7

DO - 10.1007/s00125-005-0049-7

M3 - Journal article

C2 - 16284746

VL - 49

SP - 75

EP - 82

JO - Diabetologia

JF - Diabetologia

SN - 0012-186X

IS - 1

ER -

ID: 45578331