The P-domain or trefoil motif: a role in renewal and pathology of mucous epithelia?
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
By analogy with epidermal growth factor and EGF-like repeats, the P-domain, or trefoil motif, is a characteristic shuffled module containing six invariant cysteine residues that forms the basic unit for a family of mucin-associated peptides. These P-domain peptides are potential modulators of cell growth and they are also expressed under certain pathological conditions. Furthermore, P-domains have been found as components of extracellular mosaic proteins including certain mucins, where they are thought to play a role either in protein-protein or in lectin-like interactions.
Originalsprog | Engelsk |
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Tidsskrift | Trends in Biochemical Sciences |
Vol/bind | 18 |
Udgave nummer | 7 |
Sider (fra-til) | 239-43 |
Antal sider | 5 |
ISSN | 0968-0004 |
DOI | |
Status | Udgivet - jul. 1993 |
ID: 347886032