Stine Helene Falsig Pedersen

Stine Helene Falsig Pedersen

Professor

ORCID: 0000-0002-3044-7714

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  1. Published

    Sensors and signal transduction pathways in vertebrate cell volume regulation.

    Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2006, In: Contributions to Nephrology. 152, p. 54-104 50 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Effectors and signaling events activated by cell shrinkage in ehrlich ascites tumor cells: implications for cell proliferation and programmed cell death.

    Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2004, In: Advances in Experimental Medicine and Biology. 559, p. 169-78 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Sensors and signal transduction in the activation of cell volume regulatory ion transport systems

    Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 1998, In: Contrib. Nephrol.. 123, p. 50-78

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Effectors and signalling events activated by cell shrinkage in Ehrlich ascites tumor cells: implication for cell proliferation and programmed cell death

    Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2004, Int. Cell Volume and signal transduction. New York: Kluwer/Plenum Publishers, p. 1-10

    Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research

  5. Published

    12th Acta Physiologica International Symposium "cell volume control in health and disease.".

    Hoffmann, E. K., Lambert, Ian Henry & Pedersen, Stine Helene Falsig, 2006, In: Acta Physiologica (Print Edition). 187, 1-2, p. 1-3 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Signaling mechanisms regulating the Na+/H+ Exchanger NHE1 in Pleuronectes americanus and Amphiuma tridactylum

    Holt, M. E. V., King, S. A., Rigor, R. R., Cala, P. M. & Pedersen, Stine Helene Falsig, 2003, In: The FASEB Journal. Vol. 19 (4), p. A139-A140

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Roles of Rho GTPases in the Regulation of Swelling-Activated Osmolyte Efflux in NIH3T3 mouse fibroblasts

    Hougaard, C., Pedersen, Stine Helene Falsig, Jensen, K. H., Lambert, Ian Henry & Hoffmann, E. K., 2001.

    Research output: Contribution to conference › Conference abstract for conference › Research

  8. Published

    The Na+/H+ exchanger NHE1 localizes as clusters to cryptic lamellipodia and accelerates collective epithelial cell migration

    Jensen, H. H., Pedersen, G. A., Morgen, J. J., Parsons, M., Pedersen, Stine Helene Falsig & Nejsum, L. N., 2019, In: Journal of Physiology. 597, 3, p. 849-867

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Cell swelling activates cloned Ca(2+)-activated K(+) channels: a role for the F-actin cytoskeleton.

    Jorgensen, N. K., Pedersen, Stine Helene Falsig, Rasmussen, Hanne Borger, Grunnet, Morten, Klærke, Dan Arne & Olesen, Søren-Peter, 2003, In: BBA General Subjects. 1615, 1-2, p. 115-25 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Increases in [Ca2+]i and changes in intracellular pH during chemical anoxia in mouse neocortical neurons in primary culture.

    Jørgensen, N. K., Pedersen, Stine Helene Falsig, Damgaard, I., Schousboe, A. & Hoffmann, E. K., 1999, In: Journal of Neuroscience Research. 56, p. 358-370

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Thrombin-, bradykinin-, and arachidonic acid-induced Ca2+ signaling in Ehrlich ascites tumor cells.

    Jørgensen, N. K., Pedersen, Stine Helene Falsig & Hoffmann, E. K., 1999, In: Am. J. Physiol.. 276, p. C26-C37

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Yeast recombinant production of intact human membrane proteins with long intrinsically disordered intracellular regions for structural studies

    Kassem, N., Kassem, M. M., Pedersen, Stine Helene Falsig, Pedersen, Per Amstrup & Kragelund, Birthe Brandt, 2020, In: Biochimica et Biophysica Acta - Biomembranes. 1862, 6, 14 p., 183272.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Sialylation of N-glycans affects the lipid secretion governed by specialized secretory lysosomal organelles through an effect on the V-ATPase

    Khoder-Agha, F., Song, Ming, Borre, M. T., Marinova, I. N., Ye, Z., Pedersen, Stine Helene Falsig, Dabelsteen, Sally & Wandall, Hans H., 2022, In: Glycobiology. 32, 11, p. 1012-1013 2 p., P103.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  14. Published

    Two distinct domains involved in amiloride inhibition of the Na+/H+Exchanger, NHE1.

    King, S. A., Pedersen, Stine Helene Falsig & Cala, P. M., 2005, In: FASEB Journal. Vol. 19 (5), p. A1585

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Temperature-dependent structural changes in intrinsically disordered proteins: formation of alpha-helices or loss of polyproline II?

    Kjærgaard, M., Nørholm, A., Hendus-Altenburger, R., Pedersen, Stine Helene Falsig, Poulsen, F. M. & Kragelund, Birthe Brandt, 1 Aug 2010, In: Protein Science. 19, 8, p. 1555-64 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Modulation of the transient receptor potential vanilloid channel TRPV4 by 4alpha-phorbol esters: a structure-activity study

    Klausen, T. K., Pagani, A., Minassi, A., Ech-Chahad, A., Prenen, J., Owsianik, G., Hoffmann, E. K., Pedersen, Stine Helene Falsig, Appendino, G. & Nilius, B., 2009, In: Journal of Medicinal Chemistry. 52, 9, p. 2933-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Cholesterol modulates the volume-regulated anion current in Ehrlich-Lettre ascites cells via effects on Rho and F-actin.

    Klausen, T. K., Hougaard, C., Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2006, In: American Journal of Physiology: Cell Physiology. 291, 4, p. C757-71

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Cell cycle-dependent activity of the volume- and Ca2+-activated anion currents in Ehrlich lettre ascites cells.

    Klausen, T. K., Bergdahl, A., Christophersen, P., Pedersen, Stine Helene Falsig & Hoffmann, E. K., 2007, In: Journal of Cellular Physiology. 210, 3, p. 831-42 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Monovalent ions control proliferation of Ehrlich Lettre ascites cells

    Klausen, T. K., Preisler, S., Pedersen, Stine Helene Falsig & Hoffmann, E. K., 1 Sep 2010, In: American Journal of Physiology (Consolidated). 299, 3, p. C714-25

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Single point mutations of aromatic residues in transmembrane helices 5 and -6 differentially affect TRPV4 activation by 4α-PDD and hypotonicity: implications for the role of the pore region in regulating TRPV4 activity

    Klausen, T. K., Janssens, A., Prenen, J., Owsianik, G., Hoffmann, E. K., Pedersen, Stine Helene Falsig & Nilius, B., 2014, In: Cell Calcium. 55, 1, p. 38-47 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Monocarboxylate transporters MCT1 and MCT4 regulate migration and invasion of pancreatic ductal adenocarcinoma cells

    Kong, S. C., Nøhr-Nielsen, A., Zeeberg, K., Reshkin, S. J., Hoffmann, E. K., Novak, Ivana & Pedersen, Stine Helene Falsig, 2016, In: Pancreas. 45, 7, p. 1036-1047 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Acid-base transport in pancreatic cancer: molecular mechanisms and clinical potential

    Kong, S. C., Giannuzzo, A., Novak, Ivana & Pedersen, Stine Helene Falsig, 2014, In: Biochemistry and Cell Biology. 92, 6, p. 449-459 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  23. Published

    Cell volume regulation: physiology and pathophysiology

    Lambert, Ian Henry, Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2008, In: Acta Physiologica (Print Edition). 194, 4, p. 255-82 27 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Activation of PLA2 isoforms by cell swelling and ischaemia/hypoxia

    Lambert, Ian Henry, Pedersen, Stine Helene Falsig & Poulsen, K. A., 2006, In: Acta Physiologica (Print Edition). 187, 1-2, p. 75-85

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Multiple PLA2 isoforms regulate taurine release in NIH3T3 mouse fibroblasts.

    Lambert, Ian Henry & Pedersen, Stine Helene Falsig, 2006, In: Advances in Experimental Medicine and Biology. 583, p. 99-108 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Gram-scale solution-phase synthesis of selective sodium bicarbonate Co-transport Inhibitor S0859: in vitro efficacy studies in breast cancer cells

    Larsen, A. M., Krogsgaard-Larsen, N., Lauritzen, G., Olesen, C. W., Hansen, S. H., Bødtkjer, E., Pedersen, Stine Helene Falsig & Bunch, Lennart, 2012, In: ChemMedChem. 7, 10, p. 1808-1814 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Why Warburg Works: Lactate Controls Immune Evasion through GPR81

    Jørgensen, Kathrine Lundø, Trauelsen, Mette, Pedersen, Stine Helene Falsig & Schwartz, Thue W., 2020, In: Cell Metabolism. 31, 4, p. 666–668 3 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  28. Published

    NBCn1 and NHE1 expression and activity in DeltaNErbB2 receptor-expressing MCF-7 breast cancer cells: contributions to pHi regulation and chemotherapy resistance

    Lauritzen, G., Jensen, M. B. F., Bødtkjer, E., Dybboe, R., Aalkjær, Christian, Nylandsted, J. & Pedersen, Stine Helene Falsig, 10 Sep 2010, In: Experimental Cell Research. 316, 15, p. 2538-53 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    The Na+/H+ exchanger NHE1, but not the Na+, HCO3- cotransporter NBCn1, regulates motility of MCF7 breast cancer cells expressing constitutively active ErbB2

    Lauritzen, G., Stock, C., Lemaire, J., Lund, S. F., Jensen, M. F., Damsgaard, B., Petersen, K. S., Wiwel, M., Rønnov-Jessen, Lone, Schwab, A. & Pedersen, Stine Helene Falsig, 2012, In: Cancer Letters. 317, 2, p. 172-183 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Disrupting Na+,HCO3--cotransporter NBCn1 (Slc4a7) delays murine breast cancer development

    Lee, S., Axelsen, T. V., Andersen, Anne Poder, Vahl, P., Pedersen, Stine Helene Falsig & Bødtkjer, E. B., 2016, In: Oncogene. 35, 16, p. 2112–2122 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Na+,HCO3--cotransporter NBCn1 (Slc4a7) accelerates ErbB2-induced breast cancer development and tumor growth in mice

    Lee, S., Axelsen, T. V., Jesse, N., Pedersen, Stine Helene Falsig, Vahl, P. & Boedtkjer, E., 2018, In: Oncogene. 37, 41, p. 5569-5584

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Roles of the cytoskeleton and of Protein Phosphorylation Events in the Osmotic Stress Response in EEL Intestinal Epithelium

    Lionetto, M. G., Pedersen, Stine Helene Falsig, Hoffmann, E. K., Giordano, M. E. & Schettino, T., 2002, In: Cellular Physiology and Biochemistry. 12, 4, p. 163-178 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    pH regulation in sensitive and multidrug resistant Ehrlich ascites tumor cells

    Litman, Thomas, Pedersen, Stine Helene Falsig, Kramhøft, B., Skovsgaard, T. & Hoffmann, E. K., 1998, In: Cell. Physiol. Biochem.. 8, p. 138-150

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Transmembrane transporter proteins: Capturing transport in motion

    Loland, Claus Juul, Wellendorph, Petrine, Pedersen, Stine Helene Falsig & Gether, Ulrik, 2024, In: Basic and Clinical Pharmacology and Toxicology. 134, 2, p. 203-205 3 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  35. Published

    Characteristics of summer-time energy exchange in a high Arctic tundra heath 2000-2010

    Lund, M., Hansen, Birger, Pedersen, Stine Helene Falsig, Stiegler, C. & Tamstorf, M. P., 2014, In: Tellus B: Chemical and Physical Meteorology. 66

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Lactate receptor GPR81 drives breast cancer growth and invasiveness through regulation of ECM properties and Notch ligand DLL4

    Jørgensen, Kathrine Lundø, Dmytriyeva, O., Spøhr, L., Alves, Eliana Carolina Goncalves, Yao, Jiayi, Puig Blasco, Laia, Trauelsen, Mette, Ponniah, M., Severin, M., Sandelin, Albin Gustav, Kveiborg, Marie, Schwartz, Thue W. & Pedersen, Stine Helene Falsig, 2023, In: BMC Cancer. 23, 1, 20 p., 1136.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Hyperosmotic stress regulates the distribution and stability of myocardin-related transcription factor, a key modulator of the cytoskeleton

    Ly, D. L., Waheed, F., Lodyga, M., Speight, P., Masszi, A., Nakano, H., Hersom, M. N. S., Pedersen, Stine Helene Falsig, Szászi, K. & Kapus, A., 2013, In: American Journal of Physiology: Cell Physiology. 304, 2, p. C115-C127 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    On the role of TRPC1 in control of Ca2+ influx, cell volume, and cell cycle

    Madsen, C. P., Klausen, T. K., Fabian, A., Hansen, B. J., Pedersen, Stine Helene Falsig & Hoffmann, E. K., 2012, In: American Journal of Physiology: Cell Physiology. 303, 6, p. C625-C634 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    TGFβ Signaling Increases Net Acid Extrusion, Proliferation and Invasion in Panc-1 Pancreatic Cancer Cells: SMAD4 Dependence and Link to Merlin/NF2 Signaling

    Malinda, R. R., Zeeberg, K., Sharku, P. C., Ludwig, M. Q., Pedersen, Lotte Bang, Christensen, Søren Tvorup & Pedersen, Stine Helene Falsig, 2020, In: Frontiers in Oncology. 10, 15 p., 687.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Intracellular pH gradients in migrating cells

    Martin, C., Pedersen, Stine Helene Falsig, Schwab, A. & Stock, C., 2011, In: American Journal of Physiology: Cell Physiology. 300, 3, p. C490-C495 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    MCT4 and CD147 colocalize with MMP14 in invadopodia and support matrix degradation and invasion by breast cancer cells

    Meng, Signe, Sørensen, E. E., Ponniah, M., Thorlacius-Ussing, J., Crouigneau, R., Larsen, T., Borre, M. T., Willumsen, N., Flinck, M. & Pedersen, Stine Helene Falsig, 2024, In: Journal of Cell Science. 137, 8, 15 p., jcs261608.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Effect of cytochalasins on F-actin and morphology of Ehrlich ascites tumor cells.

    Mills, J. W., Pedersen, Stine Helene Falsig, Walmod, P. S. & Hoffmann, E. K., 2000, In: Experimental Cell Research. 261, 1, p. 209-19 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    TGF-β1 regulates the expression and transcriptional activity of TAZ protein via a Smad3-independent, myocardin-related transcription factor-mediated mechanism

    Miranda, M. Z., Bialik, J. F., Speight, P., Dan, Q., Yeung, T., Szaszi, K., Pedersen, Stine Helene Falsig & Kapus, A., 2017, In: Journal of Biological Chemistry. 292, 36, p. 14902-14920 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Protein receptor-independent plasma membrane remodeling by HAMLET: a tumoricidal protein-lipid complex

    Nadeem, A., Sanborn, J., Gettel, D. L., Ho C.S., J., Rydström, A., Ngassam, V. N., Klausen, T. K., Pedersen, Stine Helene Falsig, Lam, M., Parikh, A. N. & Svanborg, C., 2015, In: Scientific Reports. 5, 14 p., 16432.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    HER2-encoded mir-4728 forms a receptor-independent circuit with miR-21-5p through the non-canonical poly(A) polymerase PAPD5

    Newie, I., Søkilde, R., Persson, H., Jacomasso, T., Gorbatenko, A., Borg, Å., de Hoon, M., Pedersen, Stine Helene Falsig & Rovira, C., 2016, In: Scientific Reports. 6, 10 p., 35664.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    PDGFRβ and oncogenic mutant PDGFRα D842V promote disassembly of primary cilia through a PLCγ- and AURKA-dependent mechanism

    Nielsen, B. S., Malinda, R. R., Schmid, F. M., Pedersen, Stine Helene Falsig, Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2015, In: Journal of Cell Science. 128, p. 3543-3549 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Structural modeling and electron paramagnetic resonance spectroscopy of the human Na+/H+ exchanger isoform 1, NHE1

    Nygaard, E. B., Lagerstedt, J. O., Bjerre, G., Shi, B., Budamagunta, M., Poulsen, K. A., Lundby, S. M., Rigor, R. R., Voss, J. C., Cala, P. M. & Pedersen, Stine Helene Falsig, 2011, In: The Journal of Biological Chemistry. 286, 1, p. 634-48 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Heat shock protein 70 inhibits shrinkage-induced programmed cell death via mechanisms independent of effects on cell volume-regulatory membrane transport proteins.

    Nylandsted, J., Jäättelä, M., Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2004, In: Pflügers Archiv: European Journal of Physiology. 449, 2, p. 175-85 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    The Intracellular Distal Tail of the Na+/H+ Exchanger NHE1 Is Intrinsically Disordered: Implications for NHE1 Trafficking

    Nørholm, A., Hendus-Altenburger, R., Bjerre, G., Kjærgaard, M., Pedersen, Stine Helene Falsig & Kragelund, Birthe Brandt, 2011, In: Biochemistry. 50, 17, p. 3469-80 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Trafficking, localization and degradation of the Na+,HCO3- Co-transporter NBCn1 in kidney and breast epithelial cells

    Olesen, C. W., Vogensen, J., Axholm, I., Severin, M., Schnipper, J., Pedersen, I. S., von Stemann, J. H., Schrøder, J. M., Christensen, D. P. & Pedersen, Stine Helene Falsig, 2018, In: Scientific Reports. 8, p. 1-16 7435.

    Research output: Contribution to journal › Journal article › Research › peer-review

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