Lone Rønnov-Jessen
Associate Professor
Cell Biology and Physiology
Universitetsparken 13
2100 København Ø
- 2024
- Published
Evidence of steady-state fibroblast subtypes in the normal human breast as cells-of-origin for perturbed-state fibroblasts in breast cancer
Bagger, M. M., Sjölund, J., Kim, Jiyoung, Kohler, Katharina Theresa, Villadsen, René, Jafari Kermani, Abbas, Kassem, Moustapha Saad El-Deen, Pietras, K., Rønnov-Jessen, Lone & Petersen, Ole William, 2024, In: Breast Cancer Research. 26, 1, 19 p., 11.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Myoepithelial progenitors as founder cells of hyperplastic human breast lesions upon PIK3CA transformation
Goldhammer, N., Kim, Jiyoung, Villadsen, René, Rønnov-Jessen, Lone & Petersen, Ole William, 2022, In: Communications Biology . 5, 1, 13 p., 219.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ductal keratin 15+ luminal progenitors in normal breast exhibit a basal-like breast cancer transcriptomic signature
Kohler, Katharina Theresa, Goldhammer, N., Demharter, S., Pfisterer, U., Khodosevich, Konstantin, Rønnov-Jessen, Lone, Petersen, Ole William, Villadsen, René & Kim, Jiyoung, 2022, In: npj Breast Cancer. 8, 1, 12 p., 81.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Desensitization of human breast progenitors by a transient exposure to pregnancy levels of estrogen
Rønnov-Jessen, Lone, Kim, Jiyoung, Goldhammer, N., Klitgaard, M. C., Smicius, M., Bechmann, M. B., Villadsen, René & Petersen, Ole William, 2021, In: Scientific Reports. 11, 7 p., 17232.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Fibroblasts direct differentiation of human breast epithelial progenitors
Morsing, M., Kim, Jiyoung, Villadsen, René, Goldhammer, N., Jafari Kermani, Abbas, Kassem, Moustapha Saad El-Deen, Petersen, Ole William & Rønnov-Jessen, Lone, 2020, In: Breast Cancer Research. 22, 16 p., 102.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
A CD146 FACS Protocol Enriches for Luminal Keratin 14/19 Double Positive Human Breast Progenitors
Ísberg, Ó. G., Kim, Jiyoung, Fridriksdottir, A. J., Morsing, M., Timmermans-Wielenga, V., Rønnov-Jessen, Lone, Petersen, Ole William & Villadsen, René, 2019, In: Scientific Reports. 9, 11 p., 14843.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Aggressiveness of non-EMT breast cancer cells relies on FBXO11 activity
Bagger, Sofie Morsing, Hopkinson, B. M., Pandey, D. P., Bak, M., Brydholm, A. V., Villadsen, René, Helin, K., Rønnov-Jessen, Lone, Petersen, Ole William & Kim, Jiyoung, 2018, In: Molecular Cancer. 17, 1, p. 1-6 6 p., 171.Research output: Contribution to journal › Comment/debate › Research › peer-review
- 2017
- Published
Proof of region-specific multipotent progenitors in human breast epithelia
Fridriksdottir, A. J., Villadsen, René, Morsing, M., Klitgaard, M. C., Kim, Jiyoung, Petersen, Ole William & Rønnov-Jessen, Lone, 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 47, p. E10102–E10111Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Establishment of a normal-derived estrogen receptor-positive cell line comparable to the prevailing human breast cancer subtype
Hopkinson, B. M., Klitgaard, M. C., Petersen, Ole William, Villadsen, René, Rønnov-Jessen, Lone & Kim, Jiyoung, 7 Feb 2017, In: OncoTarget. 8, 6, p. 10580-10593 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Evidence of two distinct functionally specialized fibroblast lineages in breast stroma
Morsing, M., Klitgaard, M. C., Jafari Kermani, Abbas, Villadsen, René, Kassem, Moustapha Saad El-Deen, Petersen, Ole William & Rønnov-Jessen, Lone, 2016, In: Breast Cancer Research (Online). 18, 11 p., 108.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Propagation of oestrogen receptor-positive and oestrogen-responsive normal human breast cells in culture
Fridriksdóttir, A. J. R., Kim, Jiyoung, Villadsen, René, Klitgaard, M. C., Hopkinson, B. M., Petersen, Ole William & Rønnov-Jessen, Lone, 2015, In: Nature Communications. 6, 12 p., 8786.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity
Kim, Jiyoung, Villadsen, René, Sørlie, T., Fogh, L., Grønlund, S. Z., Fridriksdóttir, A. J. R., Kuhn, I., Rank, F., Wielenga, V. T., Solvang, H., Edwards, P. A. W., Børresen-Dale, A., Rønnov-Jessen, Lone, Bissell, M. J. & Petersen, Ole William, 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 16, p. 6124-6129 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Na+/H+ exchanger NHE1, but not the Na+, HCO3- cotransporter NBCn1, regulates motility of MCF7 breast cancer cells expressing constitutively active ErbB2
Lauritzen, G., Stock, C., Lemaire, J., Lund, S. F., Jensen, M. F., Damsgaard, B., Petersen, K. S., Wiwel, M., Rønnov-Jessen, Lone, Schwab, A. & Pedersen, Stine Helene Falsig, 2012, In: Cancer Letters. 317, 2, p. 172-183 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Mammary gland stem cells: current status and future challenges
Fridriksdottir, A. J. R., Petersen, Ole William & Rønnov-Jessen, Lone, 2011, In: International Journal of Developmental Biology. 55, 7-9, p. 719-29 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Epithelial-stromal interaction 1 (EPSTI1) substitutes for peritumoral fibroblasts in the tumor microenvironment
De Neergaard, M., Kim, Jiyoung, Villadsen, René, Fridriksdóttir, A. J. R., Rank, F., Timmermans-Wielenga, V., Langerød, A., Børresen-Dale, A., Petersen, Ole William & Rønnov-Jessen, Lone, 2010, In: American Journal of Pathology. 176, 3, p. 1229-1240 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Breast cancer by proxy: can the microenvironment be both the cause and consequence?
Rønnov-Jessen, Lone & Bissell, M. J., 2009, In: Trends in Molecular Medicine. 15, 1, p. 5-13 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Dissection of a stem cell hierarchy in the human breast
Rubner Fridriksdottir, A. J., Villadsen, René, Kim, Jiyoung, Rønnov-Jessen, Lone & Petersen, Ole William, 2008, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. p. 412 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Expression, regulation and function of epithelial-stromal interaction 1 (breast), EPSTI1
Villadsen, R., Lind Nielsen, H., Rank, F., Petersen, O. W., Rønnov-Jessen, Lone & Neergaard, M. D., 2008, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 5, p. 430-431 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- 2007
- Published
Evidence for a stem cell hierarchy in the adult human breast
Villadsen, René, Fridriksdottir, A. J., Rønnov-Jessen, Lone, Gudjonsson, T., Rank, F., LaBarge, M. A., Bissell, M. J. & Petersen, Ole William, 2007, In: Journal of Cell Biology. 177, 1, p. 87-101 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
Immortalization protocols used in cell culture models of human breast morphogenesis
Gudjonsson, T., Villadsen, René, Rønnov-Jessen, Lone & Petersen, O. W., 2004, In: Cellular and molecular life sciences : CMLS. 61, 19-20, p. 2523-34 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Collagen gel contraction serves to rapidly distinguish epithelial- and mesenchymal-derived cells irrespective of alpha-smooth muscle actin expression
Nielsen, H. L., Gudjonsson, T., Villadsen, René, Rønnov-Jessen, Lone & Petersen, Ole William, 2004, In: In Vitro Cellular & Developmental Biology - Animal. 39, 7, p. 297-303 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
To create the correct microenvironment: Three-dimensional heterotypic collagen assays for human breast epithelial morphogenesis and neoplasia
Gudjonsson, T., Rønnov-Jessen, Lone, Villadsen, René, Bissell, M. J. & Petersen, Ole William, 2003, In: Methods. Vol. 30, p. 247-255Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Epithelial progenitor cell lines as models of normal breast morphogenesis and neoplasia
Petersen, Ole William, Gudjonsson, T., Villadsen, René, Bissell, M. J. & Rønnov-Jessen, Lone, 2003, In: Cell Proliferation. 36 Suppl 1, p. 33-44 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Epithelial to Mesenchymal Transition in Human Breast Cancer Can Provide a Nonmalignant Stroma
Petersen, Ole William, Nielsen, H. L., Gudjonsson, T., Villadsen, René, Rank, F. E., Niebuhr, E., Bisell, M. J. & Rønnov-Jessen, Lone, 2003, In: American Journal og Pathology. Vol. 162, p. 391-402Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stamceller
Rønnov-Jessen, Lone & Petersen, Ole William, 2003, In: Naturens Verden. Vol. 86, p. 24-29Research output: Contribution to journal › Journal article › Research
- 2002
- Published
Isolation, immortalization, and characterization of a human breast epithelial cell line with stem cell properties
Gudjonsson, T., Villadsen, René, Nielsen, H. L., Rønnov-Jessen, Lone, Bissell, M. J. & Petersen, Ole William, 2002, In: Genes Dev. vol. 16(6), p. 693-706Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Normal and tumor-derived myoepithelial cells differ in their ability to interact with luminal breast epithelial cells for polarity and basement membrane deposition
Gudjonsson, T., Rønnov-Jessen, Lone, Villadsen, René, Rank, F. E., Bissell, M. J. & Petersen, Ole William, 2002, In: Journal of Cell Science. 115, p. 39-50Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of EPSTI1, a novel gene induced by epithelial-stromal interaction in human breast cancer
Nielsen, H. L., Rønnov-Jessen, Lone, Villadsen, René & Petersen, Ole William, 2002, In: Genomics. 79, 5, p. 703-10 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential expression of a chloride intracellular channel gene, CLIC4, in transforming growth factor-β1-mediated conversion of fibroblasts to myofibroblasts
Rønnov-Jessen, Lone, Villadsen, René, Edwards, J. C. & Petersen, Ole William, 2002, In: American Journal of Pathology. 161, 2, p. 471-480 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2001
- Published
The plasticity of human breast carcinoma cells is more than epithelial to mesenchymal conversion
Petersen, Ole William, Nielsen, H. L., Gudjonsson, T., Villadsen, René, Rønnov-Jessen, Lone & Bissell, M. J., 2001, In: Breast Cancer Research (Online Edition). 3, p. 213-217Research output: Contribution to journal › Review › Research
- 1999
- Published
Human mammary luminal cells contain progenitors to myoepithelial cells.
Péchoux, C., Gudjonsson, T., Rønnov-Jessen, Lone, Bissell, M. J. & Petersen, O. W., 1999, In: Dev. Biol.. 206, p. 88-99Research output: Contribution to journal › Journal article › Research › peer-review
- 1998
- Published
Differentiation and cancer in the mammary gland: shedding light on an old dichotomy
Petersen, Ole William, Rønnov-Jessen, Lone, Weaver, V. M. & Bissell, M. J., 1998, In: Advances in Cancer Research. 75, p. 135-61 26 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1996
- Published
A function for filamentous alpha-smooth muscle actin: Retardation of motility in human breast fibroblasts
Rønnov-Jessen, Lone & Petersen, Ole William, 1996, In: Journal of Cell Biology. 134, 1, p. 67-80Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADP-ribosylation of actins in fibroblasts and myofibroblasts by botulinum C2 toxin: Influence on microfilament morphology and migratory behavior
Rønnov-Jessen, Lone & Petersen, Ole William, 1996, In: Electrophoresis. 17, 11, p. 1776-1780Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cellular changes involved in conversion of normal to malignant breast: The importance of the stromal reaction
Rønnov-Jessen, Lone, Petersen, Ole William & Bissell, M. J., 1996, In: Physiological Reviews. 76, p. 69-125Research output: Contribution to journal › Review › Research
- Published
Stromal reaction to invasive cancer: The cellular origin of the myofibroblast and implications for tumor development
Rønnov-Jessen, Lone, 1996, In: Breast Journal. 2, p. 320-339Research output: Contribution to journal › Review › Research
- 1995
- Published
The microenvironment of the breast: Three-dimensional models to study the roles of the stroma and the extracellular matrix in function and dysfunction
Petersen, Ole William, Rønnov-Jessen, Lone & Bissell, M. J., 1995, In: Breast Journal. 1, p. 22-35Research output: Contribution to journal › Review › Research
- Published
The origin of myofibroblasts in breast cancer: Recapitulation of tumor environment in culture unravels diversity and implicates converted fibroblasts and recruited smooth muscle cells in conversion
Rønnov-Jessen, Lone, Petersen, Ole William, Koteliansky, V. & Bissell, M. J., 1995, In: Journal of Clinical Investigation. 95, p. 859-873Research output: Contribution to journal › Journal article › Research › peer-review
- 1993
- Published
Induction of alpha-smooth muscle actin by transforming growth factor-beta1 in quiescent human breast gland fibroblasts. Implications for myofibroblast generation in breast neoplasia
Rønnov-Jessen, Lone & Petersen, O. W., 1993, In: Lab Invest. 68, 6, p. 696-707Research output: Contribution to journal › Journal article › Research
- Published
Effects of lymphocytes and fibroblasts on the growth of human mammary carcinoma cells studied in short-term primary cultures
Ögmundsdöttir, H. M., Pétursdöttir, I., Gudmundsdöttir, I., Amundadöttir, L., Rønnov-Jessen, Lone & Petersen, O. W., 1993, In: In Vitro Cell Dev Biology. Vol 29A, p. 936-942Research output: Contribution to journal › Journal article › Research › peer-review
- 1992
- Published
Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant breast epithelial cells
Petersen, Ole William, Rønnov-Jessen, Lone, Howlett, A. & Bissell, M. J., 1992, In: Proceedings of the National Academy of Science of the United States of America. 89, p. 9064-9068Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A fibroblast-associated antigen: Characterization in fibroblasts and immunoreactivity in smooth muscle differentiated stromal cells
Rønnov-Jessen, Lone, Celis, J. E., van Deurs, B. & Petersen, Ole William, 1992, In: Journal of Histochemistry and Cytochemistry. 40, 4, p. 475-486Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification, paracrine generation and possible function of human breast carcinoma myofibroblasts in culture
Rønnov-Jessen, Lone, van Deurs, B., Nielsen, M. & Petersen, Ole William, 1992, In: In Vitro Cellular & Developmental Biology - Animal. 28A, p. 273-283Research output: Contribution to journal › Journal article › Research › peer-review
- 1991
- Published
Fibroblast differentering og tumorcelle-fibroblast interaktion i den humane mammakirtel
Rønnov-Jessen, Lone, 1991Research output: Book/Report › Report › Research
- 1990
- Published
- Published
Smooth muscle differentiation in cultured human breast gland stromal cells
Rønnov-Jessen, Lone, van Deurs, B., Celis, J. E. & Petersen, Ole William, 1990, In: Laboratory Investigation. 63, 4, p. 532-543Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4950
Most downloads
-
287
downloads
Propagation of oestrogen receptor-positive and oestrogen-responsive normal human breast cells in culture
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
244
downloads
Evidence of two distinct functionally specialized fibroblast lineages in breast stroma
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
182
downloads
Establishment of a normal-derived estrogen receptor-positive cell line comparable to the prevailing human breast cancer subtype
Research output: Contribution to journal › Journal article › Research › peer-review
Published