Karsten Kristiansen

Karsten Kristiansen

Professor

  • Genome Research and Molecular Bio Medicine

    Universitetsparken 13, 2100 København Ø, August Krogh Bygningen, Building: 6. sal

    Phone: +45 35 32 44 43

  1. 2010
  2. Published

    Quercetin enhances adiponectin secretion by a PPAR-gamma independent mechanism

    Wein, S., Behm, N., Petersen, R. K., Kristiansen, Karsten & Wolffram, S., 11 Sep 2010, In: European Journal of Pharmaceutical Sciences. 41, 1, p. 16-22 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Cross talk between insulin and bone morphogenetic protein signaling systems in brown adipogenesis

    Zhang, H., Schulz, T. J., Espinoza, D. O., Huang, T. L., Emanuelli, Brice, Kristiansen, Karsten & Tseng, Y., 1 Sep 2010, In: Molecular and Cellular Biology. 30, 17, p. 4224-33 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Sequencing of 50 human exomes reveals adaptation to high altitude

    Yi, X., Liang, Y., Huerta-Sanchez, E., Jin, X., Cuo, Z. X. P., Pool, J. E., Xu, X., Jiang, H., Vinckenbosch, N., Korneliussen, Thorfinn Sand, Zheng, H., Liu, T., He, W., Li, K., Luo, R., Nie, X., Wu, H., Zhao, M., Cao, H., Zou, J., Shan, Y., Li, S., Yang, Q., Asan, G., Ni, P., Tian, G., Xu, J., Liu, X., Jiang, T., Wu, R., Zhou, G., Tang, M., Qin, J., Wang, T., Feng, S., Li, G., Huasang, G., Luosang, J., Wang, W., Chen, F., Wang, Y., Zheng, X., Li, Z., Bianba, Z., Yang, G., Wang, X., Tang, S., Gao, G., Yong, C., Luo, Z., Gusang, L., Cao, Z., Zhang, Q., Ouyang, W., Ren, X., Liang, H., Zheng, H., Huang, Y., Li, J., Bolund, L., Kristiansen, Karsten, Li, Y., Zhang, Y., Zhang, X., Li, R., Li, S., Yang, H., Nielsen, Rasmus, Wang, J. & Wang, J., 2 Jul 2010, In: Science. 329, 5987, p. 75-8 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Ancient human genome sequence of an extinct Palaeo-Eskimo

    Rasmussen, M., Li, Y., Lindgreen, Stinus, Pedersen, J. S., Albrechtsen, Anders, Moltke, Ida, Metspalu, M., Metspalu, E., Kivisild, T., Gupta, R., Bertalan, M., Nielsen, K., Gilbert, M Thomas P, Wang, Y., Raghavan, M., Campos, P., Kamp, Hanne Louise Munkholm, Wilson, A. S., Gledhill, A., Tridico, S., Bunce, M., Lorenzen, Eline, Binladen, J. K. M. A., Guo, X., Zhao, J., Zhang, X., Zhang, H., Li, Z., Chen, M., Orlando, L. A. A., Kristiansen, Karsten, Bak, Mads, Tommerup, Niels, Bendixen, C., Pierre, T. L., Grønnow, B., Meldgaard, Morten, Andreasen, C., Fedorova, S. A., Osipova, L. P., Higham, T. F. G., Ramsey, C. B., Hansen, T. V. O., Nielsen, Finn Cilius, Crawford, M. H., Brunak, Søren, Sicheritz-Pontén, T., Villems, R., Nielsen, Rasmus, Krogh, Anders, Wang, J. & Willerslev, Eske, 11 Feb 2010, In: Nature. 463, 7282, p. 757-762 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    UCP1 induction during recruitment of brown adipocytes in white adipose tissue is dependent on cyclooxygenase activity

    Madsen, L., Pedersen, L. M., Lillefosse, H. H., Fjaere, E., Bronstad, I., Hao, Q., Petersen, R. K., Hallenborg, P., Ma, T., De Matteis, R., Araujo, P., Mercader, J., Bonet, M. L., Hansen, Jacob B., Cannon, B., Nedergaard, J., Wang, J., Cinti, S., Voshol, P., Døskeland, S. O. & Kristiansen, Karsten, 30 Jan 2010, In: PLoS ONE. 5, 6, p. 1-13 111391 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The DNA methylome of human peripheral blood mononuclear cells

    Li, Y., Zhu, J., Tian, G., Li, N., Li, Q., Ye, M., Zheng, H., Yu, J., Wu, H., Sun, J., Zhang, H., Chen, Q., Luo, R., Chen, M., He, Y., Jin, X., Zhang, Q., Yu, C., Zhou, G., Sun, J., Huang, Y., Zheng, H., Cao, H., Zhou, X., Guo, S., Hu, X., Li, X., Kristiansen, Karsten, Bolund, L., Xu, J., Wang, W., Yang, H., Wang, J., Li, R., Beck, S., Wang, J. & Zhang, X., 1 Jan 2010, In: PLoS - Biology. 8, 11, p. e1000533-e1000533

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    A human gut microbial gene catalogue established by metagenomic sequencing

    MetaHIT Consortium, M. C., 2010, In: Nature. 464, 7285, p. 59-65 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    ADD1/SREBP1c activates the PGC1-alpha promoter in brown adipocytes

    Hao, Q., Hansen, Jacob B., Petersen, R. K., Hallenborg, P., Jørgensen, C., Cinti, S., Larsen, P. J., Steffensen, K. R., Wang, H., Collins, S., Wang, J., Gustafsson, J., Madsen, L. & Kristiansen, Karsten, 2010, In: BBA General Subjects. 1801, 4, p. 421-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Building the sequence map of the human pan-genome

    Li, R., Li, Y., Zheng, H., Luo, R., Zhu, H., Li, Q., Qian, W., Ren, Y., Tian, G., Li, J., Zhou, G., Zhu, X., Wu, H., Qin, J., Jin, X., Li, D., Cao, H., Hu, X., Blanche, H., Cann, H., Zhang, X., Li, S., Bolund, L., Kristiansen, Karsten, Yang, H., Wang, J. & Wang, J., 2010, In: Nature Biotechnology. 28, 1, p. 57-63 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    De novo assembly of human genomes with massively parallel short read sequencing

    Li, R., Zhu, H., Ruan, J., Qian, W., Fang, X., Shi, Z., Li, Y., Li, S., Shan, G., Kristiansen, Karsten, Li, S., Yang, H., Wang, J. & Wang, J., 2010, In: Genome Research. 20, 2, p. 265-72 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Deep RNA sequencing at single base-pair resolution reveals high complexity of the rice transcriptome

    Zhang, G., Guo, G., Hu, X., Zhang, Y., Li, Q., Li, R., Zhuang, R., Lu, Z., He, Z., Fang, X., Chen, L., Tian, W., Tao, Y., Kristiansen, Karsten, Zhang, X., Li, S., Yang, H., Wang, J. & Wang, J., 2010, In: Genome Research. 20, 5, p. 646-54 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Epidermis-type lipoxygenase 3 regulates adipocyte differentiation and peroxisome proliferator-activated receptor gamma activity

    Hallenborg, P., Jørgensen, Claus Bøttcher, Petersen, R. K., Feddersen, S., Araujo, P., Markt, P., Langer, T., Furstenberger, G., Krieg, P., Koppen, A., Kalkhoven, E., Madsen, L. & Kristiansen, Karsten, 2010, In: Molecular and Cellular Biology. 30, 16, p. 4077-91 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Identification of bioactive compounds from flowers of black elder (Sambucus nigra L.) that activate the human peroxisome proliferator-activated receptor (PPAR) gamma

    Christensen, K. B., Petersen, R. K., Kristiansen, Karsten & Christensen, L. P., 2010, In: Phytotherapy Research. 24, Suppl 2, p. 129-32

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Persistent Organic Pollutant Exposure Leads to Insulin Resistance Syndrome

    Ruzzin, J., Petersen, R., Meugnier, E., Madsen, L., Lock, E., Lillefosse, H., Ma, T., Pesenti, S., Sonne, Si Brask, Marstrand, T. T., Malde, M. K., Du, Z., Chavey, C., Fajas, L., Lundebye, A., Brand, C. L., Vidal, H., Kristiansen, Karsten & Frøyland, L., 2010, In: Environmental Health Perspectives. 118, 4, p. 465-71

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants

    Li, Y., Vinckenbosch, N., Tian, G., Huerta-Sanchez, E., Jiang, T., Jiang, H., Albrechtsen, Anders, Andersen, G., Cao, H., Korneliussen, Thorfinn Sand, Grarup, Niels, Guo, Y., Hellman, I., Jin, X., Li, Q., Liu, J., Liu, X., Sparsø, T., Tang, M., Wu, H., Wu, R., Yu, C., Zheng, H., Astrup, Arne, Bolund, L., Holmkvist, J., Jørgensen, T., Kristiansen, Karsten, Schmitz, O., Schwartz, Thue W., Zhang, X., Li, R., Yang, H., Wang, J., Hansen, Torben, Pedersen, Oluf Borbye, Nielsen, Rasmus & Wang, J., 2010, In: Nature Genetics. 42, 11, p. 969-72 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Single base-resolution methylome of the silkworm reveals a sparse epigenomic map

    Xiang, H., Zhu, J., Chen, Q., Dai, F., Li, X., Li, M., Zhang, H., Zhang, G., Li, D., Dong, Y., Zhao, L., Lin, Y., Cheng, D., Yu, J., Sun, J., Zhou, X., Ma, K., He, Y., Zhao, Y., Guo, S., Ye, M., Guo, G., Li, Y., Li, R., Zhang, X., Ma, L., Kristiansen, Karsten, Guo, Q., Jiang, J., Beck, S., Xia, Q., Wang, W. & Wang, J., 2010, In: Nature Biotechnology. 28, 5, p. 516-20 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Structure-activity study of dihydrocinnamic acids and discovery of the potent FFA1 (GPR40) agonist TUG-469

    Ulven, Elisabeth Rexen, Due-Hansen, M. E., Urban, C., Merten, N., Pfleiderer, M., Karlsen, K. K., Rasmussen, S. S., Steensgaard, M., Hamacher, A., Schmidt, J., Drewke, C., Petersen, R. K., Kristiansen, Karsten, Ullrich, S., Kostenis, E., Kassack, M. U. & Ulven, Trond, 2010, In: ACS Medicinal Chemistry Letters. 1, 7, p. 345-349 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  19. Published

    The MAPK-dependent regulation of the Jagged/Notch gene expression by VEGF, bFGF or PPAR gamma mediated angiogenesis in HUVEC

    Kiec-Wilk, B., Grzybowska-Galuszka, J., Polus, A., Pryjma, J., Knapp, A. & Kristiansen, Karsten, 2010, In: Journal of Physiology and Pharmacology. 61, 2, p. 217-25 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation

    Barbatelli, G., Murano, I., Madsen, L., Hao, Q., Jimenez, M., Kristiansen, Karsten, Giacobino, J. P., Matteis, R. D. & Cinti, S., 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 298, 6, p. E1244-E1253

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The importance of dietary modulation of cAMP and insulin signaling in adipose tissue and the development of obesity

    Madsen, L. & Kristiansen, Karsten, 2010, In: Annals of the New York Academy of Sciences. 1190, 1, p. 1-14 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The sequence and de novo assembly of the giant panda genome

    Li, R., Fan, W., Tian, G., Zhu, H., He, L., Cai, J., Huang, Q., Cai, Q., Li, B., Bai, Y., Zhang, Z., Zhang, Y., Wang, W., Li, J., Wei, F., Li, H., Jian, M., Li, J., Zhang, Z., Nielsen, Rasmus, Li, D., Gu, W., Yang, Z., Xuan, Z., Ryder, O. A., Leung, F. C., Zhou, Y., Cao, J., Sun, X., Fu, Y., Fang, X., Guo, X., Wang, B., Hou, R., Shen, F., Mu, B., Ni, P., Lin, R., Qian, W., Wang, G., Yu, C., Nie, W., Wang, J., Wu, Z., Liang, H., Min, J., Wu, Q., Cheng, S., Ruan, J., Wang, M., Shi, Z., Wen, M., Liu, B., Ren, X., Zheng, H., Dong, D., Cook, K., Shan, G., Zhang, H., Kosiol, C., Xie, X., Lu, Z., Zheng, H., Li, Y., Steiner, C. C., Lam, T. T., Lin, S., Zhang, Q., Li, G., Tian, J., Gong, T., Liu, H., Zhang, D., Fang, L., Ye, C., Zhang, J., Hu, W., Xu, A., Ren, Y., Zhang, G., Bruford, M. W., Li, Q., Ma, L., Guo, Y., An, N., Hu, Y., Zheng, Y., Shi, Y., Li, Z., Liu, Q., Chen, Y., Zhao, J., Qu, N., Zhao, S., Tian, F., Wang, X., Wang, H., Xu, L., Liu, X., Vinar, T., Wang, Y., Lam, T., Yiu, S., Liu, S., Zhang, H., Li, D., Huang, Y., Wang, X., Yang, G., Jiang, Z., Wang, J., Qin, N., Li, L., Li, J., Bolund, L., Kristiansen, Karsten, Wong, G. K., Olson, M., Zhang, X., Li, S., Yang, H., Wang, J. & Wang, J., 2010, In: Nature. 463, 7279, p. 311-317 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    beta-oxidation modulates metabolic competition between eicosapentaenoic acid and arachidonic acid regulating prostaglandin E(2) synthesis in rat hepatocytes-Kupffer cells

    Du, Z., Ma, T., Winterthun, S., Kristiansen, Karsten, Frøyland, L. & Madsen, L., 2010, In: BBA General Subjects. 1801, 4, p. 526-36 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 6489714