Karsten Kristiansen

Karsten Kristiansen

Professor

  • Genome Research and Molecular Bio Medicine

    Universitetsparken 13, 2100 København Ø, August Krogh Bygningen, Building: 6. sal

    Phone: +45 35 32 44 43

  1. 2017
  2. Published

    Links between dietary protein sources, the gut microbiota, and obesity

    Madsen, L., Myrmel, L. S., Fjære, E., Liaset, B. & Kristiansen, Karsten, 19 Dec 2017, In: Frontiers in Physiology. 8, 12 p., 1047.

    Research output: Contribution to journalReviewResearchpeer-review

  3. Published

    Comprehensive genomic profiling of lung cancer using a validated panel to explore therapeutic targets in East Asian patients

    Liu, L., Liu, J., Shao, D., Deng, Q., Tang, H., Liu, Z., Chen, X., Guo, F., Lin, Y., Mao, M., Kristiansen, Karsten, Ye, M. & He, J., Dec 2017, In: Cancer Science. 108, 12, p. 2487-2494 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Analyses of gut microbiota and plasma bile acids enable stratification of patients for antidiabetic treatment

    Gu, Y., Wang, X., Li, J., Zhang, Y., Zhong, H., Liu, R., Zhang, D., Feng, Q., Xie, X., Hong, J., Ren, H., Liu, W., Ma, J., Su, Q., Zhang, H., Yang, J., Wang, X., Zhao, X., Gu, W., Bi, Y., Peng, Y., Xu, X., Xia, H., Li, F., Xu, X., Yang, H., Xu, G., Madsen, L., Kristiansen, Karsten, Ning, G. & Wang, W., 27 Nov 2017, In: Nature Communications. 8, 12 p., 1785.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The microbiota continuum along the female reproductive tract and its relation to uterine-related diseases

    Chen, C., Song, X., Wei, W., Zhong, H., Dai, J., Lan, Z., Li, F., Yu, X., Feng, Q., Wang, Z., Xie, H., Chen, X., Zeng, C., Wen, B., Zeng, L., Du, H., Tang, H., Xu, C., Xia, Y., Xia, H., Yang, H., Wang, J., Wang, J., Madsen, L., Brix, S., Kristiansen, Karsten, Xu, X., Li, J., Wu, R. & Jia, H., 17 Oct 2017, In: Nature Communications. 8, 1, 11 p., 875.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    The gut microbiome in atherosclerotic cardiovascular disease

    Jie, Z., Xia, H., Zhong, S., Feng, Q., Li, S., Liang, S., Zhong, H., Liu, Z., Gao, Y., Zhao, H., Zhang, D., Su, Z., Fang, Z., Lan, Z., Li, J., Xiao, L., Li, J., Li, R., Li, X., Li, F., Ren, H., Huang, Y., Peng, Y., Li, G., Wen, B., Dong, B., Chen, J., Geng, Q., Zhang, Z., Yang, H., Wang, J., Wang, J., Zhang, X., Madsen, L., Brix, S., Ning, G., Xu, X., Liu, X., Hou, Y., Jia, H., He, K. & Kristiansen, Karsten, 10 Oct 2017, In: Nature Communications. 8, 1, 12 p., 845.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Taxonomic structure and functional association of foxtail millet root microbiome

    Jin, T., Wang, Y., Huang, Y., Xu, J., Zhang, P., Wang, N., Liu, X., Chu, H., Liu, G., Jiang, H., Li, Y., Xu, J., Kristiansen, Karsten, Xiao, L., Zhang, Y., Zhang, G., Du, G., Zhang, H., Zou, H., Zhang, H., Jie, Z., Liang, S., Jia, H., Wan, J., Lin, D., Li, J., Fan, G., Yang, H., Wang, J., Bai, Y. & Xu, X., Oct 2017, In: GigaScience. 6, 10, p. 1-12 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Assembly and analysis of 100 full MHC haplotypes from the Danish population

    Jensen, J. M., Villesen, P., Friborg, R. M., Mailund, T., Besenbacher, S., Sørensen, L. M., Petersen, Bent, Sibbesen, J. A., Liu, S., Skov, L., Belling, Kirstine G, Have, C. T., Izarzugaza, J. M. G., Grosjean, M., Bork-Jensen, J., Grove, J., Als, T. D., Huang, S., Chang, Y., Xu, R., Ye, W., Rao, J., Guo, X., Sun, J., Cao, H., Ye, C., Beusekom, J. V., Espeseth, T., Flindt, E., Halager, A. E., Hellard, S. L., Hultman, C. M., Lescai, F., Li, S., Lund, O., Løngren, P., Matey-Hernandez, M. L., Mors, O., Pedersen, C. N. S., Sicheritz-Pontén, T., Sullivan, P., Syed, A., Westergaard, D., Yadav, R., Li, N., Xu, X., Hansen, Torben, Bolund, L., Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Gupta, R., Rasmussen, Simon, Børglum, A. D., Wang, J., Eiberg, Hans Rudolf Lytchoff, Kristiansen, Karsten, Brunak, Søren & Schierup, M. H., Sep 2017, In: Genome Research. 27, 9, p. 1597-1607 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Eosinophilic airway inflammation in asthmatic patients is associated with an altered airway microbiome

    Sverrild, A., Kiilerich, P., Brejnrod, A. D., Pedersen, R., Porsbjerg, Celeste Michala, Bergqvist, A., Erjefält, J. S., Kristiansen, Karsten & Backer, Vibeke, Aug 2017, In: Journal of Allergy and Clinical Immunology. 140, 2, p. 407-417 e11.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    An esophageal squamous cell carcinoma classification system that reveals potential targets for therapy

    Xiong, T., Wang, M., Zhao, J., Liu, Q., Yang, C., Luo, W., Li, X., Yang, H., Kristiansen, Karsten, Roy, B. & Zhou, Y., 25 Jul 2017, In: OncoTarget. 8, 30, p. 49851-49860 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention

    Liu, R., Hong, J., Xu, X., Feng, Q., Zhang, D., Gu, Y., Shi, J., Zhao, S., Liu, W., Wang, X., Xia, H., Liu, Z., Cui, B., Liang, P., Xi, L., Jin, J., Ying, X., Wang, X., Zhao, X., Li, W., Jia, H., Lan, Z., Li, F., Wang, R., Sun, Y., Yang, M., Shen, Y., Jie, Z., Li, J., Chen, X., Zhong, H., Xie, H., Zhang, Y., Gu, W., Deng, X., Shen, B., Xu, X., Yang, H., Xu, G., Bi, Y., Lai, S., Wang, J., Qi, L., Madsen, L., Wang, J., Ning, G., Kristiansen, Karsten & Wang, W., Jul 2017, In: Nature Medicine. 23, 7, p. 859-868 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Lipidomic profiling reveals distinct differences in plasma lipid composition in healthy, prediabetic, and type 2 diabetic individuals

    Zhong, H., Fang, C., Fan, Y., Lu, Y., Wen, B., Ren, H., Hou, G., Yang, F., Xie, H., Jie, Z., Peng, Y., Ye, Z., Wu, J., Zi, J., Zhao, G., Chen, J., Bao, X., Hu, Y., Gao, Y., Zhang, J., Yang, H., Wang, J., Madsen, L., Kristiansen, Karsten, Ni, C., Li, J. & Liu, S., Jul 2017, In: GigaScience. 6, 7, p. 1-12 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Two distinct metacommunities characterize the gut microbiota in Crohn's disease patients

    He, Q., Gao, Y., Jie, Z., Yu, X., Laursen, J. M., Xiao, L., Li, Y., Li, L., Zhang, F., Feng, Q., Li, X., Yu, J., Liu, C., Lan, P., Yan, T., Liu, X., Xu, X., Yang, H., Wang, J., Madsen, L., Brix, S., Wang, J. G., Kristiansen, Karsten & Jia, H., Jul 2017, In: GigaScience. 6, 7, p. 1–11 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Corrigendum: Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

    Forslund, K., Hildebrand, F., Nielsen, Trine, Falony, G., Le Chatelier, E., Sunagawa, S., Prifti, E., Vieira-Silva, S., Gudmundsdottir, V., Pedersen, H. K., Arumugam, Mani, Kristiansen, Karsten, Voigt, A. Y., drb459, drb459, Hercog, R., Costea, P. I., Kultima, J. R., Li, J., Jørgensen, T., Levenez, F., Doré, J., Nielsen, H. B., Brunak, Søren, Raes, J., Hansen, Torben, Wang, J., Ehrlich, S. D., Bork, P., Pedersen, Oluf Borbye & MetaHIT consortium, M. C., 3 May 2017, In: Nature. 545, 116, 1 p., 22318.

    Research output: Contribution to journalComment/debateResearch

  15. Published

    A safflower oil based high-fat/high-sucrose diet modulates the gut microbiota and liver phospholipid profiles associated with early glucose intolerance in the absence of tissue inflammation

    Danneskiold-Samsøe, N. B., Andersen, D., Radulescu, I. D., Hansen, Ann Normann, Brejnrod, A. D., Kragh, M., Madsen, T., Nielsen, C., Josefsen, K. E., Fretté, X., Fjære, E., Madsen, L., Hellgren, L. I., Brix, S. & Kristiansen, Karsten, May 2017, In: Molecular Nutrition & Food Research. 61, 5, 11 p., 1600528.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Dietary intake and adipose tissue content of long-chain n-3 PUFAs and subsequent 5-y change in body weight and waist circumference

    Jakobsen, M. U., Madsen, L., Skjøth, F., Berentzen, T. L., Halkjaer, J., Tjønneland, A., Schmidt, E. B., Sørensen, Thorkild I.A., Kristiansen, Karsten & Overvad, K., May 2017, In: The American Journal of Clinical Nutrition. 105, 5, p. 1148-1157 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    High-fat feeding rather than obesity drives taxonomical and functional changes in the gut microbiota in mice

    Xiao, L., Sonne, Si Brask, Feng, Q., Chen, N., Xia, Z., Li, X., Fang, Z., Zhang, D., Fjære, E., Midtbø, L. K., Derrien, M., Hugenholtz, F., Tang, L., Li, J., Zhang, J., Liu, C., Hao, Q., Vogel, U. B., Mortensen, A., Kleerebezem, M., Licht, T. R., Yang, H., Wang, J., Li, Y., Arumugam, Mani, Wang, J., Madsen, L. & Kristiansen, Karsten, 8 Apr 2017, In: Microbiome. 5, 12 p., 43.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Effects of Gliadin consumption on the Intestinal Microbiota and Metabolic Homeostasis in Mice Fed a High-fat Diet

    Zhang, L., Andersen, D., Roager, Henrik Munch, Bahl, M. I., Hansen, Camilla Hartmann Friis, Danneskiold-Samsøe, N. B., Kristiansen, Karsten, Radulescu, I. D., Sina, C., Frandsen, H. L., Hansen, Axel Kornerup, Brix, S., Hellgren, L. I. & Licht, T. R., 16 Mar 2017, In: Scientific Reports. 7, 13 p., 44613.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Induction of lipogenesis in white fat during cold exposure in mice: link to lean phenotype

    Flachs, P., Adamcova, K., Zouhar, P., Marques, C., Janovska, P., Viegas, I., Jones, J. G., Bardova, K., Svobodova, M., Hansikova, J., Kuda, O., Rossmeisl, M., Aune, U. L., Borkowska, A. G., Kristiansen, Karsten, Madsen, L. & Kopecky, J., Mar 2017, In: International Journal of Obesity. 41, 3, p. 372-380 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Synthesis and biological evaluation of dihydropyrano-[2,3-c]pyrazoles as a new class of PPARγ partial agonists

    Qvortrup, K., Jensen, J. F., Sørensen, M. S., Kouskoumvekaki, I., Petersen, R. K., Taboureau, O., Kristiansen, Karsten & Nielsen, T. E., 28 Feb 2017, In: PLoS ONE. 12, 2, 19 p., e0162642.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Acute infection with the intestinal parasite Trichuris muris has long-term consequences on mucosal mast cell homeostasis and epithelial integrity

    Sorobetea, D., Holm, J. B., Henningsson, H., Kristiansen, Karsten & Svensson-Frej, M., Feb 2017, In: European Journal of Immunology. 47, 2, p. 257-268 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Increased microvascular permeability in mice lacking Epac1 (Rapgef3)

    Kopperud, R. K., Rygh, C. B., Karlsen, T. V., Krakstad, C., Kleppe, R., Hoivik, E. A., Bakke, M., Tenstad, O., Selheim, F., Lidén, Å., Madsen, L., Pavlin, T., Taxt, T., Kristiansen, Karsten, Curry, F. -. E., Reed, R. K. & Døskeland, S. O., Feb 2017, In: Acta Physiologica. 219, 2, p. 441-452 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Visualization and quantification of browning using a Ucp1-2A-Luciferase knock-in mouse model

    Mao, L., Nie, B., Nie, T., Hui, X., Gao, X., Lin, X., Liu, X., Xu, Y., Tang, X., Yuan, R., Li, K., Li, P., Ding, K., Wang, Y., Xu, A., Fei, J., Han, W., Liu, P., Madsen, L., Kristiansen, Karsten, Zhou, Z., Ding, S. & Wu, D., Feb 2017, In: Diabetes. 66, 2, p. 407-417 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Analysis of 62 hybrid assembled human Y chromosomes exposes rapid structural changes and high rates of gene conversion

    Skov, L., Schierup, M. H., Danish Pan Genome Consortium, D. P. G. C., Sørensen, L. M., Petersen, Bent, Sibbesen, J. A., Liu, S., Belling, Kirstine G, Have, C. T., Bork-Jensen, J., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Rasmussen, Simon, Kristiansen, Karsten & Brunak, Søren, 2017, In: PLOS Genetics. 13, 8, p. e1006834

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Assessment of the cPAS-based BGISEQ-500 platform for metagenomic sequencing

    Fang, Chao, Zhong, H., Lin, Y., Chen, B., Han, Mo, Ren, H., Lu, H., Luber, J. M., Xia, M., Li, W., Stein, S., Xu, X., Zhang, W., Drmanac, R., Wang, J., Yang, H., Hammarström, L., Kostic, A. D., Kristiansen, Karsten & Li, J., 2017, In: GigaScience. 7, 3, p. 1-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Mammary alveolar epithelial cells convert to brown adipocytes in post-lactating mice

    Giordano, A., Perugini, J., Kristensen, David Møbjerg, Sartini, L., Frontini, A., Kajimura, S., Kristiansen, Karsten & Cinti, S., 2017, In: Journal of Cellular Physiology. 232, 11, p. 2923-2928 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer

    Yu, J., Feng, Q., Wong, S. H., Zhang, D., Liang, Q. Y., Qin, Y., Tang, L., Zhao, H., Stenvang, Jan, Li, Y., Wang, X., Xu, X., Chen, N., Wu, W. K. K., Al-Aama, J., Nielsen, H. J., Kiilerich, P., Jensen, Benjamin Anderschou Holbech, Yau, T. O., Lan, Z., Jia, H., Li, J., Xiao, L., Lam, T. Y. T., Ng, S. C., Cheng, A. S., Wong, V. W., Chan, F. K. L., Xu, X., Yang, H., Madsen, L., Datz, C., Tilg, H., Wang, J., Brünner, Nils, Kristiansen, Karsten, Arumugam, Mani, Sung, J. J. & Wang, J., 2017, In: Gut. 66, p. 70-78 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Obesity is associated with depot-specific alterations in adipocyte DNA methylation and gene expression

    Sonne, Si Brask, Yadav, R., Yin, G., Dalgaard, M. D., Myrmel, L. S., Gupta, R., Wang, J., Madsen, L., Kajimura, S. & Kristiansen, Karsten, 2017, In: Adipocyte. 6, 2, p. 124-133 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Prenatal exposure to paracetamol/acetaminophen and precursor aniline impairs masculinisation of male brain and behaviour

    Hay-Schmidt, A., Finkielman, O. T. E., Jensen, Benjamin Anderschou Holbech, Høgsbro, C. F., Holm, J. B., Johansen, K. H., Jensen, T. K., Andrade, A. M., Swan, S. H., Bornehag, C., Brunak, Søren, Jegou, B., Kristiansen, Karsten & Kristensen, David Møbjerg, 2017, In: Reproduction. 154, 2, p. 145-152 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Sequencing and de novo assembly of 150 genomes from Denmark as a population reference

    Sørensen, L. M., Jensen, J. M., Petersen, Bent, Sibbesen, J. A., Liu, S., Villesen, P., Skov, L., Belling, Kirstine G, Have, C. T., Izarzugaza, J. M. G., Grosjean, M., Bork-Jensen, J., Grove, J., Als, T. D., Huang, S., Chang, Y., Xu, R., Ye, W., Rao, J., Guo, X., Sun, J., Cao, H., Ye, C., van Beusekom, J., Espeseth, T., Flindt, E., Friborg, R. M., Halager, A. E., Le Hellard, S., Hultman, C. M., Lescai, F., Li, S., Lund, O., Løngren, P., Mailund, T., Matey-Hernandez, M. L., Mors, O., Pedersen, C. N. S., Sicheritz-Pontén, T., Sullivan, P., Syed, A., Westergaard, D., Yadav, R., Li, N., Xu, X., Hansen, Torben, Krogh, Anders, Bolund, L., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Gupta, R., Rasmussen, Simon, Besenbacher, S., Børglum, A. D., Wang, J., Eiberg, Hans Rudolf Lytchoff, Kristiansen, Karsten, Brunak, Søren & Schierup, M. H., 2017, In: Nature. 548, 7665, p. 87-91 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

ID: 6489714