Stine Helene Falsig Pedersen

Stine Helene Falsig Pedersen

Professor

ORCID: 0000-0002-3044-7714

Publication year:
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51 - 100 out of 177Page size: 50
  1. 2007
  2. Published

    Shrinkage insensitivity of NKCC1 in myosin II-depleted cytoplasts from Ehrlich ascites tumor cells.

    Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2007, In: American Journal of Physiology: Cell Physiology. 292, 5, p. C1854-66

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    The Na+/H+ exchanger, NHE1, differentially regulates mitogen-activated protein kinase subfamilies after osmotic shrinkage in Ehrlich Lettre Ascites cells.

    Pedersen, Stine Helene Falsig, Rasmussen, M., Darborg, B. V., Nylandsted, J. & Hoffmann, E. K., 2007, In: Cellular Physiology and Biochemistry. 20, 6, p. 735-50 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Transient receptor potential channels in mechanosensing and cell volume regulation.

    Pedersen, Stine Helene Falsig & Nilius, B., 2007, In: Methods in Enzymology. 428, p. 183-207 24 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. 2008
  6. Published

    Cell volume regulation: physiology and pathophysiology

    Lambert, Ian Henry, Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2008, In: Acta Physiologica (Print Edition). 194, 4, p. 255-82 27 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Chapter 10 the primary cilium coordinates signaling pathways in cell cycle control and migration during development and tissue repair

    Christensen, Søren Tvorup, Pedersen, Stine Helene Falsig, Satir, P., Veland, I. R. & Schneider, L., 2008, In: Current Topics in Developmental Biology. 85, p. 261-301 40 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    H-ras transformation sensitizes volume-activated anion channels and increases migratory activity of NIH3T3 fibroblasts.

    Schneider, L., Klausen, T. K., Stock, C., Mally, S., Christensen, Søren Tvorup, Pedersen, Stine Helene Falsig, Hoffmann, E. K. & Schwab, A., 2008, In: Pflügers Archiv: European Journal of Physiology. 455, 6, p. 1055-62 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Osmotic cell shrinkage activates ezrin/radixin/moesin (ERM) proteins: activation mechanisms and physiological implications

    Rasmussen, M., Alexander, R. T., Darborg, B. V., Møbjerg, Nadja, Hoffmann, E. K., Kapus , A. & Pedersen, Stine Helene Falsig, 2008, In: American Journal of Physiology: Cell Physiology. 294, 1, p. C197-C212 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. 2009
  11. Published

    HL-1 mouse cardiomyocyte injury and death after simulated ischemia and reperfusion: roles of pH, Ca2+-independent phospholipase A2, and Na+/H+ exchange

    Andersen, A., Poulsen, K. A., Lambert, Ian Henry & Pedersen, Stine Helene Falsig, 2009, In: American Journal of Physiology: Cell Physiology. 296, 5, p. C1227-42

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Hyperosmotic stress induces Rho/Rho kinase/LIM kinase-mediated cofilin phosphorylation in tubular cells: key role in the osmotically triggered F-actin response

    Thirone, A. C. P., Speight, P., Zulys, M., Rotstein, O. D., Szaszi, K., Pedersen, Stine Helene Falsig & Kapus, A., 2009, In: American Journal of Physiology: Cell Physiology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Modulation of the transient receptor potential vanilloid channel TRPV4 by 4alpha-phorbol esters: a structure-activity study

    Klausen, T. K., Pagani, A., Minassi, A., Ech-Chahad, A., Prenen, J., Owsianik, G., Hoffmann, E. K., Pedersen, Stine Helene Falsig, Appendino, G. & Nilius, B., 2009, In: Journal of Medicinal Chemistry. 52, 9, p. 2933-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Physiology of cell volume regulation in vertebrates

    Hoffmann, E. K., Lambert, Ian Henry & Pedersen, Stine Helene Falsig, 2009, In: Physiological Reviews. 89, 1, p. 193-277 84 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Propionic acid secreted from propionibacteria induces NKG2D ligand expression on human-activated T lymphocytes and cancer cells

    Andresen, Lars, Hansen, K. A., Jensen, H., Pedersen, Stine Helene Falsig, Stougaard, P., Hansen, H. R., Jurlander, J. & Skov, Søren, 2009, In: Journal of Immunology. 183, 2, p. 897-906 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The Na+/H+ exchanger NHE1 is required for directional migration stimulated via PDGFR-alpha in the primary cilium

    Schneider, L., Stock, C., Dieterich, P., Jensen, B. H., Pedersen, Lotte Bang, Satir, P., Schwab, A., Christensen, Søren Tvorup & Pedersen, Stine Helene Falsig, 2009, In: Journal of Cell Biology. 185, 1, p. 163-76 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. 2010
  18. Published

    Ion transport proteins control pancreatic cancer cell behaviour

    Schwab, A., Stock, C., Swietach, P., Hulikova, A., Vaughan-Jones, R. D., Pedersen, S. H. F., Andersen, A-D., Hoffmann, E. K., Novak, I., Reshkin, S., Prevarskaya, N., Lemonnier, L., Borowiec, A. S., Arcangeli, A., Zanieri, F., D´Amico, M., Fraser, S. P., Djamgoz, M. BA., Alves, F., Kalthoff, H. & 2 others, Pardo, L. A. & Stühmer, W., 2010, In: Acta Physiologica (Print Edition). 198, 677, p. 17 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  19. Published

    Temperature-dependent structural changes in intrinsically disordered proteins: formation of alpha-helices or loss of polyproline II?

    Kjærgaard, M., Nørholm, A., Hendus-Altenburger, R., Pedersen, Stine Helene Falsig, Poulsen, F. M. & Kragelund, Birthe Brandt, 1 Aug 2010, In: Protein Science. 19, 8, p. 1555-64 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Monovalent ions control proliferation of Ehrlich Lettre ascites cells

    Klausen, T. K., Preisler, S., Pedersen, Stine Helene Falsig & Hoffmann, E. K., 1 Sep 2010, In: American Journal of Physiology (Consolidated). 299, 3, p. C714-25

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    NBCn1 and NHE1 expression and activity in DeltaNErbB2 receptor-expressing MCF-7 breast cancer cells: contributions to pHi regulation and chemotherapy resistance

    Lauritzen, G., Jensen, M. B. F., Bødtkjer, E., Dybboe, R., Aalkjær, Christian, Nylandsted, J. & Pedersen, Stine Helene Falsig, 10 Sep 2010, In: Experimental Cell Research. 316, 15, p. 2538-53 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Ion transport proteins control pancreatic ductal adenocarcinoma

    Schwab, A., Stock, C., Swietach, P., Hulikova, A., Vaughan-Jones, R., Pedersen, S. H. F., Andersen, A. D., Hoffmann, E., Novak, I., Reshkin, S., Prevarskaya, N., Lemonnier, L., A-S, B., Fraser, S. P., Arcangeli, A., Zanieri, F., D'Amico, M., Kalthoff, H., Djamgoz, M. B., Alves, F. & 2 others, Pardo, L. & Stuehmer, W., 1 Oct 2010, In: Onkologie. 33, Suppl. 6, p. 269 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. 2011
  24. Published

    Cell Volume Regulation and Signaling in 3T3-L1 Pre-adipocytes and Adipocytes: on the Possible Roles of Caveolae, Insulin Receptors, FAK and ERK1/2

    Eduardsen, K., Larsen, S., Novak, Ivana, Lambert, Ian Henry, Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2011, In: Cellular Physiology and Biochemistry. 28, 6, p. 1231-46 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    EB1 and EB3 promote cilia biogenesis by several centrosome-related mechanisms

    Schrøder, J. M., Larsen, J., Komarova, Y., Akhmanova, A., Thorsteinsson, R. I., Grigoriev, I., Manguso, R., Christensen, Søren Tvorup, Pedersen, Stine Helene Falsig, Geimer, S. & Pedersen, Lotte Bang, 2011, In: Journal of Cell Science. 124, p. 2539-51 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Hyperosmotic stress strongly potentiates serum response factor (SRF)-dependent transcriptional activity in ehrlich lettré ascites cells through a mechanism involving p38 mitogen-activated protein kinase

    Gorbatenko, A., Wiwel, M., Klingberg, H., Nielsen, A. B., Kapus, A. & Pedersen, Stine Helene Falsig, 2011, In: Journal of Cellular Physiology. 226, 11, p. 2857-2868 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Intracellular pH gradients in migrating cells

    Martin, C., Pedersen, Stine Helene Falsig, Schwab, A. & Stock, C., 2011, In: American Journal of Physiology: Cell Physiology. 300, 3, p. C490-C495 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Osmosensory mechanisms in cellular and systemic volume regulation

    Pedersen, Stine Helene Falsig, Kapus, A. & Hoffmann, E. K., 2011, In: Journal of the American Society of Nephrology. 22, 9, p. 1587-97 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Response to Schushan et al.: Two conflicting NHE1 model structures: compatibility with experimental data and implications for the transport mechanism

    Cala, P. M. & Pedersen, Stine Helene Falsig, 2011, In: Journal of Biological Chemistry. 286, 21, p. le10 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  30. Published

    Structural modeling and electron paramagnetic resonance spectroscopy of the human Na+/H+ exchanger isoform 1, NHE1

    Nygaard, E. B., Lagerstedt, J. O., Bjerre, G., Shi, B., Budamagunta, M., Poulsen, K. A., Lundby, S. M., Rigor, R. R., Voss, J. C., Cala, P. M. & Pedersen, Stine Helene Falsig, 2011, In: The Journal of Biological Chemistry. 286, 1, p. 634-48 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    The Intracellular Distal Tail of the Na+/H+ Exchanger NHE1 Is Intrinsically Disordered: Implications for NHE1 Trafficking

    Nørholm, A., Hendus-Altenburger, R., Bjerre, G., Kjærgaard, M., Pedersen, Stine Helene Falsig & Kragelund, Birthe Brandt, 2011, In: Biochemistry. 50, 17, p. 3469-80 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    The cardioprotective effect of brief acidic reperfusion after ischemia in perfused rat hearts is not mimicked by inhibition of the Na+/H+ exchanger NHE1

    Andersen, A., Bentzen, Bo Hjorth, Salling, H., Klingberg, H., Kanneworff, M., Grunnet, Morten & Pedersen, Stine Helene Falsig, 2011, In: Cellular Physiology and Biochemistry. 28, 1, p. 13-24 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Cell volume homeostatic mechanisms: effectors and signalling pathways

    Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 27 Jan 2011, In: Acta Physiologica. 202, 3, p. 465–485

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. 2012
  35. Published

    Gram-scale solution-phase synthesis of selective sodium bicarbonate Co-transport Inhibitor S0859: in vitro efficacy studies in breast cancer cells

    Larsen, A. M., Krogsgaard-Larsen, N., Lauritzen, G., Olesen, C. W., Hansen, S. H., Bødtkjer, E., Pedersen, Stine Helene Falsig & Bunch, Lennart, 2012, In: ChemMedChem. 7, 10, p. 1808-1814 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    On the role of TRPC1 in control of Ca2+ influx, cell volume, and cell cycle

    Madsen, C. P., Klausen, T. K., Fabian, A., Hansen, B. J., Pedersen, Stine Helene Falsig & Hoffmann, E. K., 2012, In: American Journal of Physiology: Cell Physiology. 303, 6, p. C625-C634 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Physiology, pharmacology and pathophysiology of the pH regulatory transport proteins NHE1 and NBCn1: similarities, differences, and implications for cancer therapy

    Bødtkjer, E., Bunch, Lennart & Pedersen, Stine Helene Falsig, 2012, In: Current Pharmaceutical Design. 18, 10, p. 1345-1371 27 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    The Na+/H+ exchanger NHE1, but not the Na+, HCO3- cotransporter NBCn1, regulates motility of MCF7 breast cancer cells expressing constitutively active ErbB2

    Lauritzen, G., Stock, C., Lemaire, J., Lund, S. F., Jensen, M. F., Damsgaard, B., Petersen, K. S., Wiwel, M., Rønnov-Jessen, Lone, Schwab, A. & Pedersen, Stine Helene Falsig, 2012, In: Cancer Letters. 317, 2, p. 172-183 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. 2013
  40. Published

    A unifying mechanism for Cancer cell death through ion channel activation by HAMLET

    Storm, P., Klausen, T. K., Trulsson, M., Ho CS, J., Dosnon, M., Westergren, T., Chao, Y., Rydström, A., Yang, H., Pedersen, Stine Helene Falsig & Svanborg, C., 2013, In: P L o S One. 8, 3, 18 p., e58578.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Cell volume regulation in epithelial physiology and cancer

    Pedersen, Stine Helene Falsig, Hoffmann, E. K. & Novak, Ivana, 2013, In: Frontiers in Physiology. 4, 12 p., 233.

    Research output: Contribution to journal › Review › Research › peer-review

  42. Published

    Contribution of Na+,HCO3--cotransport to cellular pH control in human breast cancer: a role for the breast cancer susceptibility locus NBCn1 (SLC4A7)

    Bødtkjer, E., Moreira, José, Mele, M., Vahl, P., Wielenga, V. T., Christiansen, P. M., Jensen, V. E. D., Pedersen, Stine Helene Falsig & Aalkjær, C., 2013, In: International Journal of Cancer. 132, 6, p. 1288-1299 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Hyperosmotic stress regulates the distribution and stability of myocardin-related transcription factor, a key modulator of the cytoskeleton

    Ly, D. L., Waheed, F., Lodyga, M., Speight, P., Masszi, A., Nakano, H., Hersom, M. N. S., Pedersen, Stine Helene Falsig, Szászi, K. & Kapus, A., 2013, In: American Journal of Physiology: Cell Physiology. 304, 2, p. C115-C127 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration

    Veland, I. R., Montjean, R., Eley, L., Pedersen, Lotte Bang, Schwab, A., Goodship, J., Kristiansen, Karsten, Pedersen, Stine Helene Falsig, Saunier, S. & Christensen, Søren Tvorup, 2013, In: P L o S One. 8, 4, 15 p., e60193.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Ion channels and transporters in cancer: pathophysiology, regulation, and clinical potential

    Pedersen, Stine Helene Falsig & Stock, C., 2013, In: Cancer Research. 73, 6, p. 1658-1661 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    PDGFR alpha signaling in the primary cilium regulates NHE1-dependent fibroblast migration via coordinated differential activity of MEK1/2-ERK1/2-p90(RSK) and AKT signaling pathways

    Clement, Ditte Lynge, Mally, S., Stock, C., Lethan, M., Satir, P., Schwab, A., Pedersen, Stine Helene Falsig & Christensen, Søren Tvorup, 2013, In: Journal of Cell Science. 126, 4, p. 953-965 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. 2014
  48. Published

    Acid-base transport in pancreatic cancer: molecular mechanisms and clinical potential

    Kong, S. C., Giannuzzo, A., Novak, Ivana & Pedersen, Stine Helene Falsig, 2014, In: Biochemistry and Cell Biology. 92, 6, p. 449-459 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  49. Published

    Characteristics of summer-time energy exchange in a high Arctic tundra heath 2000-2010

    Lund, M., Hansen, Birger, Pedersen, Stine Helene Falsig, Stiegler, C. & Tamstorf, M. P., 2014, In: Tellus B: Chemical and Physical Meteorology. 66

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    ErbB2 upregulates the Na+,HCO3- -cotransporter NBCn1/SLC4A7 in human breast cancer cells via Akt, ERK, Src, and Krüppel-like factor 4

    Gorbatenko, A., Olesen, C. W., Mørup, N., Thiel, G., Kallunki, T., Valen, E. & Pedersen, Stine Helene Falsig, 2014, In: F A S E B Journal. 28, 1, p. 350-363 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Interactions of ion transporters and channels with cancer cell metabolism and the tumour microenvironment

    Andersen, Anne Poder, Moreira, José & Pedersen, Stine Helene Falsig, 2014, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 369, 1638, 11 p., 20130098.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Luminescent dual sensors reveal extracellular pH-gradients and hypoxia on chronic wounds that disrupt epidermal repair

    Schreml, S., Meier, R. J., Kirschbaum, M., Kong, S. C., Gehmert, S., Felthaus, O., Kuechler, S., Sharpe, J. R., Woeltje, K., Weiss, K. T., Albert, M., Seidl, U., Schroeder, J., Morsczeck, C., Prantl, L., Duschl, C., Pedersen, S. H. F., Gosau, M., Berneburg, M., Wolfbeis, O. S. & 2 others, Landthaler, M. & Babilas, P., 2014, In: Theranostics. 4, 7, p. 721-735 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Regulation and roles of bicarbonate transporters in cancer

    Gorbatenko, A., Olesen, C. W., Bødtkjer, E. & Pedersen, Stine Helene Falsig, 2014, In: Frontiers in Physiology. 5, 15 p., 130.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Single point mutations of aromatic residues in transmembrane helices 5 and -6 differentially affect TRPV4 activation by 4α-PDD and hypotonicity: implications for the role of the pore region in regulating TRPV4 activity

    Klausen, T. K., Janssens, A., Prenen, J., Owsianik, G., Hoffmann, E. K., Pedersen, Stine Helene Falsig & Nilius, B., 2014, In: Cell Calcium. 55, 1, p. 38-47 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Structural dynamics and regulation of the mammalian SLC9A family of Na+/H+ exchangers

    Hendus-Altenburger, R., Kragelund, Birthe Brandt & Pedersen, Stine Helene Falsig, 2014, Current Topics in Membranes: Exchangers. Bevensee, M. O. (ed.). Elsevier, Vol. 73. p. 69-148 80 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  56. 2015
  57. Published

    ANO1 (TMEM16A) in pancreatic ductal adenocarcinoma (PDAC)

    Sauter, D. R. P., Novak, Ivana, Pedersen, Stine Helene Falsig, Larsen, Erik Hviid & Hoffmann, E. K., 2015, In: Pflügers Archiv - European Journal of Physiology. 467, 7, p. 1495-1508 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Constitutively active ErbB2 regulates cisplatin-induced cell death in breast cancer cells via pro- and antiapoptotic mechanisms

    Sigurðsson, H. H., Olesen, C. W., Dybboe, R., Lauritzen, G. & Pedersen, Stine Helene Falsig, 2015, In: Molecular Cancer Research. 13, 1, p. 63-77 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Intrinsically disordered cytoplasmic domains of two cytokine receptors mediate conserved interactions with membranes

    Haxholm, G. W., Nikolajsen, L. F., Olsen, Johan Gotthardt, Fredsted, J., Larsen, F. H., Goffin, V., Pedersen, Stine Helene Falsig, Brooks, A. J., Waters, M. J. & Kragelund, Birthe Brandt, 2015, In: Biochemical Journal. 468, 3, p. 495-506 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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