Stine Helene Falsig Pedersen

Stine Helene Falsig Pedersen

Professor

ORCID: 0000-0002-3044-7714

Publication year:
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51 - 100 out of 175Page size: 50
  1. 2017
  2. Published

    Tumor microenvironment conditions alter Akt and Na+/H+ exchanger NHE1 expression in endothelial cells more than hypoxia alone: implications for endothelial cell function in cancer

    Pedersen, A., Mendes Lopes de Melo, J., Mørup, N., Tritsaris, Katerina & Pedersen, Stine Helene Falsig, 2017, In: BMC Cancer. 17, 15 p., 542.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2016
  4. Published

    Modeling the ischemic blood-brain barrier; the effects of oxygen-glucose deprivation (OGD) on endothelial cells in culture

    Tornabene, E., Helms, H. C. C., Berndt, P., Blasig, I., Pedersen, Stine Helene Falsig, Waagepetersen, Helle S. & Larsen, Birger Brodin, 19 Jun 2016.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  5. Published

    HER2-encoded mir-4728 forms a receptor-independent circuit with miR-21-5p through the non-canonical poly(A) polymerase PAPD5

    Newie, I., Søkilde, R., Persson, H., Jacomasso, T., Gorbatenko, A., Borg, Å., de Hoon, M., Pedersen, Stine Helene Falsig & Rovira, C., 2016, In: Scientific Reports. 6, 10 p., 35664.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    A bovine in vitro blood-brain barrier model under oxygenglucose deprivation (OGD) condition

    Tornabene, E., Helms, H. C. C., Berndt, P., Blasig, I., Pedersen, Stine Helene Falsig, Waagepetersen, Helle S. & Larsen, Birger Brodin, 2016.

    Research output: Contribution to conference › Poster › Research

  7. Published

    Assessment of different 3D culture systems to study tumor phenotype and chemosensitivity in pancreatic ductal adenocarcinoma

    Zeeberg, K., Cardone, R. A., Greco, M. R., Saccomano, M., Nøhr-Nielsen, A., Alves, F., Pedersen, Stine Helene Falsig & Reshkin, S. J., 2016, In: International Journal of Oncology. 49, 1, p. 243-252 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Biophysics and physiology of the volume-regulated anion channel (VRAC)/volume-sensitive outwardly rectifying anion channel (VSOR)

    Pedersen, Stine Helene Falsig, Okada, Y. & Nilius, B., 2016, In: Pflügers Archiv - European Journal of Physiology. 468, 3, p. 371-383 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Disrupting Na+,HCO3--cotransporter NBCn1 (Slc4a7) delays murine breast cancer development

    Lee, S., Axelsen, T. V., Andersen, Anne Poder, Vahl, P., Pedersen, Stine Helene Falsig & Bødtkjer, E. B., 2016, In: Oncogene. 35, 16, p. 2112–2122 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Glycosylation of solute carriers: mechanisms and functional consequences

    Pedersen, N. B., Carlsson, M. C. & Pedersen, Stine Helene Falsig, 2016, In: Pflügers Archiv - European Journal of Physiology. 468, 2, p. 159-176 18 p.

    Research output: Contribution to journal › Review › Research › peer-review

  11. Published

    Metabolism and microenvironment in cancer plasticity

    Baldini, N., Sonveaux, P., De Milito, A., Supuran, C. T., Otto, A. M., Stock, C. M., Pedersen, Stine Helene Falsig, Favicchio, R. & Avnet, S., 2016, In: Cancer & Metabolism. 4, Supplement 1, 7 p., 1.

    Research output: Contribution to journal › Comment/debate › Research

  12. Published

    Monocarboxylate transporters MCT1 and MCT4 regulate migration and invasion of pancreatic ductal adenocarcinoma cells

    Kong, S. C., Nøhr-Nielsen, A., Zeeberg, K., Reshkin, S. J., Hoffmann, E. K., Novak, Ivana & Pedersen, Stine Helene Falsig, 2016, In: Pancreas. 45, 7, p. 1036-1047 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Myocardin-related transcription factor regulates Nox4 protein expression: linking cytoskeletal orginization to redox state

    Rozycki, M., Bialik, J. F., Speight, P., Dan, Q., Knudsen, Teresa Emmilie Toudal, Szeto, S. G., Yuen, D. A., Szászi, K., Pedersen, Stine Helene Falsig & Kapus, A., 2016, In: Journal of Biological Chemistry. 291, 1, p. 227-243 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Oncogenic p95HER2 regulates Na+-HCO3- cotransporter NBCn1 mRNA stability in breast cancer cells via 3'UTR-dependent processes

    Gorbatenko, A., Olesen, C. W., Loebl, N., Sigurdsson, H. H., Bianchi, C., Pedraz Cuesta, E., Christiansen, Jan & Pedersen, Stine Helene Falsig, 2016, In: Biochemical Journal. 473, 21, p. 4027-4044 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Prolactin signaling stimulates invasion via Na+/H+ exchanger NHE1 in T47D human breast cancer cells

    Pedraz Cuesta, E., Fredsted, J., Jensen, H. H., Bornebusch, A., Nejsum, L. N., Kragelund, Birthe Brandt & Pedersen, Stine Helene Falsig, 2016, In: Molecular Endocrinology. 30, 7, p. 693-708 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Roles of acid-extruding ion transporters in regulation of breast cancer cell growth in a 3-dimensional microenvironment

    Andersen, Anne Poder, Flinck, M., Oernbo, E. K., Pedersen, N. B., Viuff, B. M. & Pedersen, Stine Helene Falsig, 2016, In: Molecular Cancer. 15, 18 p., 45.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Snowpack fluxes of methane and carbon dioxide from high Arctic tundra

    Pirk, N., Tamstorf, M. P., Lund, M., Mastepanov, M., Pedersen, Stine Helene Falsig, Mylius, M. R., Parmentier, F. W., Christiansen, H. H. & Christensen, T. R., 2016, In: Journal of Geophysical Research: Biogeosciences. 121, 11, p. 2886-2900 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    The human Na+/H+ exchanger 1 is a membrane scaffold protein for extracellular signal-regulated kinase 2

    Hendus-Altenburger, R., Pedraz Cuesta, E., Olesen, C. W., Papaleo, E., Schnell, J. A., Hopper, J. T. S., Robinson, C. V., Pedersen, Stine Helene Falsig & Kragelund, Birthe Brandt, 2016, In: BMC Biology. 14, 17 p., 31.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. 2015
  20. Published

    The in vitro blood-brain barrier model under OGD condition

    Tornabene, E., Helms, H. C. C., Berndt, P., Blasig, I., Pedersen, Stine Helene Falsig & Larsen, Birger Brodin, 2 Nov 2015.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  21. Published

    Changes in barrier properties and protein expression levels of bovine brain endothelial cells during oxygen-glucose deprivation (OGD)

    Tornabene, E., Helms, H. C. C., Berndt, P., Blasig, I., Pedersen, Stine Helene Falsig & Larsen, Birger Brodin, 27 Aug 2015.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  22. Published

    Changes in protein expression levels, Claudin-5 localization and barrier function in bovine brain endothelial cells during oxygen-glucose deprivation (OGD)

    Tornabene, E., Helms, H. C. C., Berndt, P., Blasig, I., Pedersen, Stine Helene Falsig & Larsen, Birger Brodin, 4 Jul 2015.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  23. Published

    ANO1 (TMEM16A) in pancreatic ductal adenocarcinoma (PDAC)

    Sauter, D. R. P., Novak, Ivana, Pedersen, Stine Helene Falsig, Larsen, Erik Hviid & Hoffmann, E. K., 2015, In: Pflügers Archiv - European Journal of Physiology. 467, 7, p. 1495-1508 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Constitutively active ErbB2 regulates cisplatin-induced cell death in breast cancer cells via pro- and antiapoptotic mechanisms

    Sigurðsson, H. H., Olesen, C. W., Dybboe, R., Lauritzen, G. & Pedersen, Stine Helene Falsig, 2015, In: Molecular Cancer Research. 13, 1, p. 63-77 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Intrinsically disordered cytoplasmic domains of two cytokine receptors mediate conserved interactions with membranes

    Haxholm, G. W., Nikolajsen, L. F., Olsen, Johan Gotthardt, Fredsted, J., Larsen, F. H., Goffin, V., Pedersen, Stine Helene Falsig, Brooks, A. J., Waters, M. J. & Kragelund, Birthe Brandt, 2015, In: Biochemical Journal. 468, 3, p. 495-506 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Osmotic shrinkage elicits FAK- and Src phosphorylation and Src-dependent NKCC1 activation in NIH3T3 cells

    Rasmussen, L. J. H., Mûller, H. S. H., Jørgensen, B., Pedersen, Stine Helene Falsig & Hoffmann, E. K., 2015, In: American Journal of Physiology: Cell Physiology. 308, 2, p. C101-C110 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    PDGFRβ and oncogenic mutant PDGFRα D842V promote disassembly of primary cilia through a PLCγ- and AURKA-dependent mechanism

    Nielsen, B. S., Malinda, R. R., Schmid, F. M., Pedersen, Stine Helene Falsig, Christensen, Søren Tvorup & Pedersen, Lotte Bang, 2015, In: Journal of Cell Science. 128, p. 3543-3549 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Protein receptor-independent plasma membrane remodeling by HAMLET: a tumoricidal protein-lipid complex

    Nadeem, A., Sanborn, J., Gettel, D. L., Ho C.S., J., Rydström, A., Ngassam, V. N., Klausen, T. K., Pedersen, Stine Helene Falsig, Lam, M., Parikh, A. N. & Svanborg, C., 2015, In: Scientific Reports. 5, 14 p., 16432.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    The P2X7 receptor regulates cell survival, migration and invasion of pancreatic ductal adenocarcinoma cells

    Giannuzzo, A., Pedersen, Stine Helene Falsig & Novak, Ivana, 2015, In: Molecular Cancer. 14, 15 p., 203.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells

    Cuesta, E. P., Christensen, S., Jensen, Anders A., Jensen, N. F., Bunch, Lennart, Rømer, M. U. K., Brünner, N., Stenvang, Jan & Pedersen, Stine Helene Falsig, 2015, In: B M C Cancer. 15, 1, 17 p., 411.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    The identification of a volume-regulated anion channel: an amazing Odyssey

    Pedersen, Stine Helene Falsig, Klausen, T. K. & Nilius, B., 2015, In: Acta Physiologica (Print). 213, 4, p. 868-881 14 p.

    Research output: Contribution to journal › Review › Research › peer-review

  32. 2014
  33. Published

    Acid-base transport in pancreatic cancer: molecular mechanisms and clinical potential

    Kong, S. C., Giannuzzo, A., Novak, Ivana & Pedersen, Stine Helene Falsig, 2014, In: Biochemistry and Cell Biology. 92, 6, p. 449-459 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  34. Published

    Characteristics of summer-time energy exchange in a high Arctic tundra heath 2000-2010

    Lund, M., Hansen, Birger, Pedersen, Stine Helene Falsig, Stiegler, C. & Tamstorf, M. P., 2014, In: Tellus B: Chemical and Physical Meteorology. 66

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    ErbB2 upregulates the Na+,HCO3- -cotransporter NBCn1/SLC4A7 in human breast cancer cells via Akt, ERK, Src, and Krüppel-like factor 4

    Gorbatenko, A., Olesen, C. W., Mørup, N., Thiel, G., Kallunki, T., Valen, E. & Pedersen, Stine Helene Falsig, 2014, In: F A S E B Journal. 28, 1, p. 350-363 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Interactions of ion transporters and channels with cancer cell metabolism and the tumour microenvironment

    Andersen, Anne Poder, Moreira, José & Pedersen, Stine Helene Falsig, 2014, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 369, 1638, 11 p., 20130098.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Luminescent dual sensors reveal extracellular pH-gradients and hypoxia on chronic wounds that disrupt epidermal repair

    Schreml, S., Meier, R. J., Kirschbaum, M., Kong, S. C., Gehmert, S., Felthaus, O., Kuechler, S., Sharpe, J. R., Woeltje, K., Weiss, K. T., Albert, M., Seidl, U., Schroeder, J., Morsczeck, C., Prantl, L., Duschl, C., Pedersen, S. H. F., Gosau, M., Berneburg, M., Wolfbeis, O. S. & 2 others, Landthaler, M. & Babilas, P., 2014, In: Theranostics. 4, 7, p. 721-735 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Regulation and roles of bicarbonate transporters in cancer

    Gorbatenko, A., Olesen, C. W., Bødtkjer, E. & Pedersen, Stine Helene Falsig, 2014, In: Frontiers in Physiology. 5, 15 p., 130.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Single point mutations of aromatic residues in transmembrane helices 5 and -6 differentially affect TRPV4 activation by 4α-PDD and hypotonicity: implications for the role of the pore region in regulating TRPV4 activity

    Klausen, T. K., Janssens, A., Prenen, J., Owsianik, G., Hoffmann, E. K., Pedersen, Stine Helene Falsig & Nilius, B., 2014, In: Cell Calcium. 55, 1, p. 38-47 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Structural dynamics and regulation of the mammalian SLC9A family of Na+/H+ exchangers

    Hendus-Altenburger, R., Kragelund, Birthe Brandt & Pedersen, Stine Helene Falsig, 2014, Current Topics in Membranes: Exchangers. Bevensee, M. O. (ed.). Elsevier, Vol. 73. p. 69-148 80 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  41. 2013
  42. Published

    A unifying mechanism for Cancer cell death through ion channel activation by HAMLET

    Storm, P., Klausen, T. K., Trulsson, M., Ho CS, J., Dosnon, M., Westergren, T., Chao, Y., Rydström, A., Yang, H., Pedersen, Stine Helene Falsig & Svanborg, C., 2013, In: P L o S One. 8, 3, 18 p., e58578.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Cell volume regulation in epithelial physiology and cancer

    Pedersen, Stine Helene Falsig, Hoffmann, E. K. & Novak, Ivana, 2013, In: Frontiers in Physiology. 4, 12 p., 233.

    Research output: Contribution to journal › Review › Research › peer-review

  44. Published

    Contribution of Na+,HCO3--cotransport to cellular pH control in human breast cancer: a role for the breast cancer susceptibility locus NBCn1 (SLC4A7)

    Bødtkjer, E., Moreira, José, Mele, M., Vahl, P., Wielenga, V. T., Christiansen, P. M., Jensen, V. E. D., Pedersen, Stine Helene Falsig & Aalkjær, C., 2013, In: International Journal of Cancer. 132, 6, p. 1288-1299 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Hyperosmotic stress regulates the distribution and stability of myocardin-related transcription factor, a key modulator of the cytoskeleton

    Ly, D. L., Waheed, F., Lodyga, M., Speight, P., Masszi, A., Nakano, H., Hersom, M. N. S., Pedersen, Stine Helene Falsig, Szászi, K. & Kapus, A., 2013, In: American Journal of Physiology: Cell Physiology. 304, 2, p. C115-C127 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration

    Veland, I. R., Montjean, R., Eley, L., Pedersen, Lotte Bang, Schwab, A., Goodship, J., Kristiansen, Karsten, Pedersen, Stine Helene Falsig, Saunier, S. & Christensen, Søren Tvorup, 2013, In: P L o S One. 8, 4, 15 p., e60193.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Ion channels and transporters in cancer: pathophysiology, regulation, and clinical potential

    Pedersen, Stine Helene Falsig & Stock, C., 2013, In: Cancer Research. 73, 6, p. 1658-1661 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    PDGFR alpha signaling in the primary cilium regulates NHE1-dependent fibroblast migration via coordinated differential activity of MEK1/2-ERK1/2-p90(RSK) and AKT signaling pathways

    Clement, Ditte Lynge, Mally, S., Stock, C., Lethan, M., Satir, P., Schwab, A., Pedersen, Stine Helene Falsig & Christensen, Søren Tvorup, 2013, In: Journal of Cell Science. 126, 4, p. 953-965 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. 2012
  50. Published

    Gram-scale solution-phase synthesis of selective sodium bicarbonate Co-transport Inhibitor S0859: in vitro efficacy studies in breast cancer cells

    Larsen, A. M., Krogsgaard-Larsen, N., Lauritzen, G., Olesen, C. W., Hansen, S. H., Bødtkjer, E., Pedersen, Stine Helene Falsig & Bunch, Lennart, 2012, In: ChemMedChem. 7, 10, p. 1808-1814 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    On the role of TRPC1 in control of Ca2+ influx, cell volume, and cell cycle

    Madsen, C. P., Klausen, T. K., Fabian, A., Hansen, B. J., Pedersen, Stine Helene Falsig & Hoffmann, E. K., 2012, In: American Journal of Physiology: Cell Physiology. 303, 6, p. C625-C634 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Physiology, pharmacology and pathophysiology of the pH regulatory transport proteins NHE1 and NBCn1: similarities, differences, and implications for cancer therapy

    Bødtkjer, E., Bunch, Lennart & Pedersen, Stine Helene Falsig, 2012, In: Current Pharmaceutical Design. 18, 10, p. 1345-1371 27 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    The Na+/H+ exchanger NHE1, but not the Na+, HCO3- cotransporter NBCn1, regulates motility of MCF7 breast cancer cells expressing constitutively active ErbB2

    Lauritzen, G., Stock, C., Lemaire, J., Lund, S. F., Jensen, M. F., Damsgaard, B., Petersen, K. S., Wiwel, M., Rønnov-Jessen, Lone, Schwab, A. & Pedersen, Stine Helene Falsig, 2012, In: Cancer Letters. 317, 2, p. 172-183 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. 2011
  55. Published

    Cell volume homeostatic mechanisms: effectors and signalling pathways

    Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 27 Jan 2011, In: Acta Physiologica. 202, 3, p. 465–485

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Cell Volume Regulation and Signaling in 3T3-L1 Pre-adipocytes and Adipocytes: on the Possible Roles of Caveolae, Insulin Receptors, FAK and ERK1/2

    Eduardsen, K., Larsen, S., Novak, Ivana, Lambert, Ian Henry, Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2011, In: Cellular Physiology and Biochemistry. 28, 6, p. 1231-46 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    EB1 and EB3 promote cilia biogenesis by several centrosome-related mechanisms

    Schrøder, J. M., Larsen, J., Komarova, Y., Akhmanova, A., Thorsteinsson, R. I., Grigoriev, I., Manguso, R., Christensen, Søren Tvorup, Pedersen, Stine Helene Falsig, Geimer, S. & Pedersen, Lotte Bang, 2011, In: Journal of Cell Science. 124, p. 2539-51 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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