Stine Helene Falsig Pedersen
Professor
Cell Biology and Physiology
Universitetsparken 13
2100 København Ø
- 2011
- Published
Hyperosmotic stress strongly potentiates serum response factor (SRF)-dependent transcriptional activity in ehrlich lettré ascites cells through a mechanism involving p38 mitogen-activated protein kinase
Gorbatenko, A., Wiwel, M., Klingberg, H., Nielsen, A. B., Kapus, A. & Pedersen, Stine Helene Falsig, 2011, In: Journal of Cellular Physiology. 226, 11, p. 2857-2868 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intracellular pH gradients in migrating cells
Martin, C., Pedersen, Stine Helene Falsig, Schwab, A. & Stock, C., 2011, In: American Journal of Physiology: Cell Physiology. 300, 3, p. C490-C495 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Osmosensory mechanisms in cellular and systemic volume regulation
Pedersen, Stine Helene Falsig, Kapus, A. & Hoffmann, E. K., 2011, In: Journal of the American Society of Nephrology. 22, 9, p. 1587-97 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Response to Schushan et al.: Two conflicting NHE1 model structures: compatibility with experimental data and implications for the transport mechanism
Cala, P. M. & Pedersen, Stine Helene Falsig, 2011, In: Journal of Biological Chemistry. 286, 21, p. le10 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Structural modeling and electron paramagnetic resonance spectroscopy of the human Na+/H+ exchanger isoform 1, NHE1
Nygaard, E. B., Lagerstedt, J. O., Bjerre, G., Shi, B., Budamagunta, M., Poulsen, K. A., Lundby, S. M., Rigor, R. R., Voss, J. C., Cala, P. M. & Pedersen, Stine Helene Falsig, 2011, In: The Journal of Biological Chemistry. 286, 1, p. 634-48 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Intracellular Distal Tail of the Na+/H+ Exchanger NHE1 Is Intrinsically Disordered: Implications for NHE1 Trafficking
Nørholm, A., Hendus-Altenburger, R., Bjerre, G., Kjærgaard, M., Pedersen, Stine Helene Falsig & Kragelund, Birthe Brandt, 2011, In: Biochemistry. 50, 17, p. 3469-80 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The cardioprotective effect of brief acidic reperfusion after ischemia in perfused rat hearts is not mimicked by inhibition of the Na+/H+ exchanger NHE1
Andersen, A., Bentzen, Bo Hjorth, Salling, H., Klingberg, H., Kanneworff, M., Grunnet, Morten & Pedersen, Stine Helene Falsig, 2011, In: Cellular Physiology and Biochemistry. 28, 1, p. 13-24 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Ion transport proteins control pancreatic ductal adenocarcinoma
Schwab, A., Stock, C., Swietach, P., Hulikova, A., Vaughan-Jones, R., Pedersen, S. H. F., Andersen, A. D., Hoffmann, E., Novak, I., Reshkin, S., Prevarskaya, N., Lemonnier, L., A-S, B., Fraser, S. P., Arcangeli, A., Zanieri, F., D'Amico, M., Kalthoff, H., Djamgoz, M. B., Alves, F. & 2 others, , 1 Oct 2010, In: Onkologie. 33, Suppl. 6, p. 269 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NBCn1 and NHE1 expression and activity in DeltaNErbB2 receptor-expressing MCF-7 breast cancer cells: contributions to pHi regulation and chemotherapy resistance
Lauritzen, G., Jensen, M. B. F., Bødtkjer, E., Dybboe, R., Aalkjær, Christian, Nylandsted, J. & Pedersen, Stine Helene Falsig, 10 Sep 2010, In: Experimental Cell Research. 316, 15, p. 2538-53 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Monovalent ions control proliferation of Ehrlich Lettre ascites cells
Klausen, T. K., Preisler, S., Pedersen, Stine Helene Falsig & Hoffmann, E. K., 1 Sep 2010, In: American Journal of Physiology (Consolidated). 299, 3, p. C714-25Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Temperature-dependent structural changes in intrinsically disordered proteins: formation of alpha-helices or loss of polyproline II?
Kjærgaard, M., Nørholm, A., Hendus-Altenburger, R., Pedersen, Stine Helene Falsig, Poulsen, F. M. & Kragelund, Birthe Brandt, 1 Aug 2010, In: Protein Science. 19, 8, p. 1555-64 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ion transport proteins control pancreatic cancer cell behaviour
Schwab, A., Stock, C., Swietach, P., Hulikova, A., Vaughan-Jones, R. D., Pedersen, S. H. F., Andersen, A-D., Hoffmann, E. K., Novak, I., Reshkin, S., Prevarskaya, N., Lemonnier, L., Borowiec, A. S., Arcangeli, A., Zanieri, F., D´Amico, M., Fraser, S. P., Djamgoz, M. BA., Alves, F., Kalthoff, H. & 2 others, , 2010, In: Acta Physiologica (Print Edition). 198, 677, p. 17 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- 2009
- Published
HL-1 mouse cardiomyocyte injury and death after simulated ischemia and reperfusion: roles of pH, Ca2+-independent phospholipase A2, and Na+/H+ exchange
Andersen, A., Poulsen, K. A., Lambert, Ian Henry & Pedersen, Stine Helene Falsig, 2009, In: American Journal of Physiology: Cell Physiology. 296, 5, p. C1227-42Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperosmotic stress induces Rho/Rho kinase/LIM kinase-mediated cofilin phosphorylation in tubular cells: key role in the osmotically triggered F-actin response
Thirone, A. C. P., Speight, P., Zulys, M., Rotstein, O. D., Szaszi, K., Pedersen, Stine Helene Falsig & Kapus, A., 2009, In: American Journal of Physiology: Cell Physiology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modulation of the transient receptor potential vanilloid channel TRPV4 by 4alpha-phorbol esters: a structure-activity study
Klausen, T. K., Pagani, A., Minassi, A., Ech-Chahad, A., Prenen, J., Owsianik, G., Hoffmann, E. K., Pedersen, Stine Helene Falsig, Appendino, G. & Nilius, B., 2009, In: Journal of Medicinal Chemistry. 52, 9, p. 2933-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physiology of cell volume regulation in vertebrates
Hoffmann, E. K., Lambert, Ian Henry & Pedersen, Stine Helene Falsig, 2009, In: Physiological Reviews. 89, 1, p. 193-277 84 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Propionic acid secreted from propionibacteria induces NKG2D ligand expression on human-activated T lymphocytes and cancer cells
Andresen, Lars, Hansen, K. A., Jensen, H., Pedersen, Stine Helene Falsig, Stougaard, P., Hansen, H. R., Jurlander, J. & Skov, Søren, 2009, In: Journal of Immunology. 183, 2, p. 897-906 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Na+/H+ exchanger NHE1 is required for directional migration stimulated via PDGFR-alpha in the primary cilium
Schneider, L., Stock, C., Dieterich, P., Jensen, B. H., Pedersen, Lotte Bang, Satir, P., Schwab, A., Christensen, Søren Tvorup & Pedersen, Stine Helene Falsig, 2009, In: Journal of Cell Biology. 185, 1, p. 163-76 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Cell volume regulation: physiology and pathophysiology
Lambert, Ian Henry, Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2008, In: Acta Physiologica (Print Edition). 194, 4, p. 255-82 27 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chapter 10 the primary cilium coordinates signaling pathways in cell cycle control and migration during development and tissue repair
Christensen, Søren Tvorup, Pedersen, Stine Helene Falsig, Satir, P., Veland, I. R. & Schneider, L., 2008, In: Current Topics in Developmental Biology. 85, p. 261-301 40 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
H-ras transformation sensitizes volume-activated anion channels and increases migratory activity of NIH3T3 fibroblasts.
Schneider, L., Klausen, T. K., Stock, C., Mally, S., Christensen, Søren Tvorup, Pedersen, Stine Helene Falsig, Hoffmann, E. K. & Schwab, A., 2008, In: Pflügers Archiv: European Journal of Physiology. 455, 6, p. 1055-62 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Osmotic cell shrinkage activates ezrin/radixin/moesin (ERM) proteins: activation mechanisms and physiological implications
Rasmussen, M., Alexander, R. T., Darborg, B. V., Møbjerg, Nadja, Hoffmann, E. K., Kapus , A. & Pedersen, Stine Helene Falsig, 2008, In: American Journal of Physiology: Cell Physiology. 294, 1, p. C197-C212 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
Cell cycle-dependent activity of the volume- and Ca2+-activated anion currents in Ehrlich lettre ascites cells.
Klausen, T. K., Bergdahl, A., Christophersen, P., Pedersen, Stine Helene Falsig & Hoffmann, E. K., 2007, In: Journal of Cellular Physiology. 210, 3, p. 831-42 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Induction of group VIA phospholipase A2 activity during in vitro ischemia in C2C12 myotubes is associated with changes in the level of its splice variants.
Poulsen, K. A., Pedersen, Stine Helene Falsig, Kolko, M. & Lambert, Ian Henry, 2007, In: American Journal of Physiology: Cell Physiology. 293, 5, p. C1605-15Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NHE1 inhibition by amiloride- and benzoylguanidine-type compounds. Inhibitor binding loci deduced from chimeras of NHE1 homologues with endogenous differences in inhibitor sensitivity.
Pedersen, Stine Helene Falsig, King, S. A., Nygaard, E. B., Rigor, R. R. & Cala, P. M., 2007, In: Journal of Biological Chemistry. 282, 27, p. 19716-27 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Roles of Na+/H+ exchange in regulation of p38 mitogen-activated protein kinase activity and cell death after chemical anoxia in NIH3T3 fibroblasts.
Rentsch, M. L., Ossum, C. G., Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2007, In: Pflügers Archiv: European Journal of Physiology. 454, 4, p. 649-62 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Shrinkage insensitivity of NKCC1 in myosin II-depleted cytoplasts from Ehrlich ascites tumor cells.
Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2007, In: American Journal of Physiology: Cell Physiology. 292, 5, p. C1854-66Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Na+/H+ exchanger, NHE1, differentially regulates mitogen-activated protein kinase subfamilies after osmotic shrinkage in Ehrlich Lettre Ascites cells.
Pedersen, Stine Helene Falsig, Rasmussen, M., Darborg, B. V., Nylandsted, J. & Hoffmann, E. K., 2007, In: Cellular Physiology and Biochemistry. 20, 6, p. 735-50 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transient receptor potential channels in mechanosensing and cell volume regulation.
Pedersen, Stine Helene Falsig & Nilius, B., 2007, In: Methods in Enzymology. 428, p. 183-207 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
12th Acta Physiologica International Symposium "cell volume control in health and disease.".
Hoffmann, E. K., Lambert, Ian Henry & Pedersen, Stine Helene Falsig, 2006, In: Acta Physiologica (Print Edition). 187, 1-2, p. 1-3 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Activation of PLA2 isoforms by cell swelling and ischaemia/hypoxia
Lambert, Ian Henry, Pedersen, Stine Helene Falsig & Poulsen, K. A., 2006, In: Acta Physiologica (Print Edition). 187, 1-2, p. 75-85Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cholesterol modulates the volume-regulated anion current in Ehrlich-Lettre ascites cells via effects on Rho and F-actin.
Klausen, T. K., Hougaard, C., Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2006, In: American Journal of Physiology: Cell Physiology. 291, 4, p. C757-71Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of chemical anoxia on NHE1, p38 MAPK, p53, Akt and ERM proteins in NIH3T3 fibroblasts: evidence for a role of NHE1 upstream of p38 MAPK
Rentsch, M. L., Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2006, In: The FASEB Journal. 5, p. A1158Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Multiple PLA2 isoforms regulate taurine release in NIH3T3 mouse fibroblasts.
Lambert, Ian Henry & Pedersen, Stine Helene Falsig, 2006, In: Advances in Experimental Medicine and Biology. 583, p. 99-108 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physiology and pathophysiology of Na+/H+ exchange and Na+-K+-2Cl- cotransport in the heart, brain, and blood
Pedersen, Stine Helene Falsig, O´Donnell, M. E., Anderson, S. E. & Cala, P. M., 2006, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 291, 1, p. R1-R25Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of mitogen-activated protein kinase pathways by the plasma membrane Na+/H+ exchanger, NHE1.
Pedersen, Stine Helene Falsig, Darborg, B. V., Rentsch, M. L. & Rasmussen, M., 2006, In: Archives of Biochemistry and Biophysics. 462, 2, p. 195-201 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Roles of phospholipase A2 isoforms in swelling- and melittin-induced arachidonic acid release and taurine efflux in NIH3T3 fibroblasts.
Pedersen, Stine Helene Falsig, Poulsen, K. A. & Lambert, Ian Henry, 2006, In: American Journal of Physiology: Cell Physiology. 291, 6, p. C 1286-1296Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sensors and signal transduction pathways in vertebrate cell volume regulation.
Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2006, In: Contributions to Nephrology. 152, p. 54-104 50 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Na+/H+ exchanger NHE1 in stress-induced signal transduction: implications for cell proliferation and cell death.
Pedersen, Stine Helene Falsig, 2006, In: Pflügers Archiv: European Journal of Physiology. 452, 3, p. 249-59 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Causal relationship between NHE1, NKCC1, MAPKs and ERM proteins after osmotic shrinkage in Ehrlich Lettremouse ascites tumor cells.
Darborg, B., Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2005, In: The FASEB Journal. 5, p. A1155Research output: Contribution to journal › Conference article › Research › peer-review
- Published
TRP channels: an overview.
Pedersen, Stine Helene Falsig, Owsianik, G. & Nilius, B., 2005, In: Cell Calcium. 38, 3-4, p. 233-52 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two distinct domains involved in amiloride inhibition of the Na+/H+Exchanger, NHE1.
King, S. A., Pedersen, Stine Helene Falsig & Cala, P. M., 2005, In: FASEB Journal. Vol. 19 (5), p. A1585Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
A novel NHE1 from red blood cells of the winter flounder: regulation by multiple signaling pathways.
Pedersen, Stine Helene Falsig, 2004, In: Advances in Experimental Medicine and Biology. 559, p. 89-98 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative biology of the ubiquitous Na+/H+ exchanger, NHE1: lessons from erythrocytes.
Pedersen, Stine Helene Falsig & Cala, P. M., 2004, In: Journal of experimental zoology. Part A, Comparative experimental biology. 301, 7, p. 569-78 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effectors and signaling events activated by cell shrinkage in ehrlich ascites tumor cells: implications for cell proliferation and programmed cell death.
Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2004, In: Advances in Experimental Medicine and Biology. 559, p. 169-78 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effectors and signalling events activated by cell shrinkage in Ehrlich ascites tumor cells: implication for cell proliferation and programmed cell death
Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2004, Int. Cell Volume and signal transduction. New York: Kluwer/Plenum Publishers, p. 1-10Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research
- Published
Heat shock protein 70 inhibits shrinkage-induced programmed cell death via mechanisms independent of effects on cell volume-regulatory membrane transport proteins.
Nylandsted, J., Jäättelä, M., Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2004, In: Pflügers Archiv: European Journal of Physiology. 449, 2, p. 175-85 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hsp-70 mediated protection of WEHI cells against hypertonic stress-induced programmed cell death by a mechanism independent of effects on volume-regulatory membrane transport proteins
Pedersen, Stine Helene Falsig, Larsen, J. N., Hoffmann, E. K. & Jaattela, M., 2004, In: The FASEB Journal. 18 (5), p. A1284 suppl.s.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of the expression and subcellular localization of the taurine transporter TauT in mouse NIH3T3 fibroblasts
Voss, J. W., Pedersen, Stine Helene Falsig, Christensen, Søren Tvorup & Lambert, Ian Henry, 2004, In: European Journal of Biochemistry. 271, p. 4646-4658Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Signal transduction mechanisms involved in the rgulation of NHE1 from Pseudopleuronectes Americanus red blood cells by osmotic shrinkage , ß-adrenergic stimuli, and calyculin A
Pedersen, Stine Helene Falsig, Holt, M., King, S. A. & Cala, P. M., 2004, In: Bull. Mount Desert Island Biol. Lab. 43, p. 9-11Research output: Contribution to journal › Journal article › Research › peer-review
ID: 8742
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Annual Meeting of the International Society of Cancer Metabolism (ISCaM): metabolic networks in cancer
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Cell volume regulation in epithelial physiology and cancer
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Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration
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