Stine Helene Falsig Pedersen

Stine Helene Falsig Pedersen

Professor


  1. 2011
  2. Published

    Hyperosmotic stress strongly potentiates serum response factor (SRF)-dependent transcriptional activity in ehrlich lettré ascites cells through a mechanism involving p38 mitogen-activated protein kinase

    Gorbatenko, A., Wiwel, M., Klingberg, H., Nielsen, A. B., Kapus, A. & Pedersen, Stine Helene Falsig, 2011, In: Journal of Cellular Physiology. 226, 11, p. 2857-2868 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Intracellular pH gradients in migrating cells

    Martin, C., Pedersen, Stine Helene Falsig, Schwab, A. & Stock, C., 2011, In: American Journal of Physiology: Cell Physiology. 300, 3, p. C490-C495 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Osmosensory mechanisms in cellular and systemic volume regulation

    Pedersen, Stine Helene Falsig, Kapus, A. & Hoffmann, E. K., 2011, In: Journal of the American Society of Nephrology. 22, 9, p. 1587-97 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Response to Schushan et al.: Two conflicting NHE1 model structures: compatibility with experimental data and implications for the transport mechanism

    Cala, P. M. & Pedersen, Stine Helene Falsig, 2011, In: Journal of Biological Chemistry. 286, 21, p. le10 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  6. Published

    Structural modeling and electron paramagnetic resonance spectroscopy of the human Na+/H+ exchanger isoform 1, NHE1

    Nygaard, E. B., Lagerstedt, J. O., Bjerre, G., Shi, B., Budamagunta, M., Poulsen, K. A., Lundby, S. M., Rigor, R. R., Voss, J. C., Cala, P. M. & Pedersen, Stine Helene Falsig, 2011, In: The Journal of Biological Chemistry. 286, 1, p. 634-48 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The Intracellular Distal Tail of the Na+/H+ Exchanger NHE1 Is Intrinsically Disordered: Implications for NHE1 Trafficking

    Nørholm, A., Hendus-Altenburger, R., Bjerre, G., Kjærgaard, M., Pedersen, Stine Helene Falsig & Kragelund, Birthe Brandt, 2011, In: Biochemistry. 50, 17, p. 3469-80 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The cardioprotective effect of brief acidic reperfusion after ischemia in perfused rat hearts is not mimicked by inhibition of the Na+/H+ exchanger NHE1

    Andersen, A., Bentzen, Bo Hjorth, Salling, H., Klingberg, H., Kanneworff, M., Grunnet, Morten & Pedersen, Stine Helene Falsig, 2011, In: Cellular Physiology and Biochemistry. 28, 1, p. 13-24 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2010
  10. Published

    Ion transport proteins control pancreatic ductal adenocarcinoma

    Schwab, A., Stock, C., Swietach, P., Hulikova, A., Vaughan-Jones, R., Pedersen, S. H. F., Andersen, A. D., Hoffmann, E., Novak, I., Reshkin, S., Prevarskaya, N., Lemonnier, L., A-S, B., Fraser, S. P., Arcangeli, A., Zanieri, F., D'Amico, M., Kalthoff, H., Djamgoz, M. B., Alves, F. & 2 others, Pardo, L. & Stuehmer, W., 1 Oct 2010, In: Onkologie. 33, Suppl. 6, p. 269 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    NBCn1 and NHE1 expression and activity in DeltaNErbB2 receptor-expressing MCF-7 breast cancer cells: contributions to pHi regulation and chemotherapy resistance

    Lauritzen, G., Jensen, M. B. F., Bødtkjer, E., Dybboe, R., Aalkjær, Christian, Nylandsted, J. & Pedersen, Stine Helene Falsig, 10 Sep 2010, In: Experimental Cell Research. 316, 15, p. 2538-53 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Monovalent ions control proliferation of Ehrlich Lettre ascites cells

    Klausen, T. K., Preisler, S., Pedersen, Stine Helene Falsig & Hoffmann, E. K., 1 Sep 2010, In: American Journal of Physiology (Consolidated). 299, 3, p. C714-25

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Temperature-dependent structural changes in intrinsically disordered proteins: formation of alpha-helices or loss of polyproline II?

    Kjærgaard, M., Nørholm, A., Hendus-Altenburger, R., Pedersen, Stine Helene Falsig, Poulsen, F. M. & Kragelund, Birthe Brandt, 1 Aug 2010, In: Protein Science. 19, 8, p. 1555-64 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Ion transport proteins control pancreatic cancer cell behaviour

    Schwab, A., Stock, C., Swietach, P., Hulikova, A., Vaughan-Jones, R. D., Pedersen, S. H. F., Andersen, A-D., Hoffmann, E. K., Novak, I., Reshkin, S., Prevarskaya, N., Lemonnier, L., Borowiec, A. S., Arcangeli, A., Zanieri, F., D´Amico, M., Fraser, S. P., Djamgoz, M. BA., Alves, F., Kalthoff, H. & 2 others, Pardo, L. A. & Stühmer, W., 2010, In: Acta Physiologica (Print Edition). 198, 677, p. 17 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  15. 2009
  16. Published

    HL-1 mouse cardiomyocyte injury and death after simulated ischemia and reperfusion: roles of pH, Ca2+-independent phospholipase A2, and Na+/H+ exchange

    Andersen, A., Poulsen, K. A., Lambert, Ian Henry & Pedersen, Stine Helene Falsig, 2009, In: American Journal of Physiology: Cell Physiology. 296, 5, p. C1227-42

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Hyperosmotic stress induces Rho/Rho kinase/LIM kinase-mediated cofilin phosphorylation in tubular cells: key role in the osmotically triggered F-actin response

    Thirone, A. C. P., Speight, P., Zulys, M., Rotstein, O. D., Szaszi, K., Pedersen, Stine Helene Falsig & Kapus, A., 2009, In: American Journal of Physiology: Cell Physiology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Modulation of the transient receptor potential vanilloid channel TRPV4 by 4alpha-phorbol esters: a structure-activity study

    Klausen, T. K., Pagani, A., Minassi, A., Ech-Chahad, A., Prenen, J., Owsianik, G., Hoffmann, E. K., Pedersen, Stine Helene Falsig, Appendino, G. & Nilius, B., 2009, In: Journal of Medicinal Chemistry. 52, 9, p. 2933-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Physiology of cell volume regulation in vertebrates

    Hoffmann, E. K., Lambert, Ian Henry & Pedersen, Stine Helene Falsig, 2009, In: Physiological Reviews. 89, 1, p. 193-277 84 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Propionic acid secreted from propionibacteria induces NKG2D ligand expression on human-activated T lymphocytes and cancer cells

    Andresen, Lars, Hansen, K. A., Jensen, H., Pedersen, Stine Helene Falsig, Stougaard, P., Hansen, H. R., Jurlander, J. & Skov, Søren, 2009, In: Journal of Immunology. 183, 2, p. 897-906 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The Na+/H+ exchanger NHE1 is required for directional migration stimulated via PDGFR-alpha in the primary cilium

    Schneider, L., Stock, C., Dieterich, P., Jensen, B. H., Pedersen, Lotte Bang, Satir, P., Schwab, A., Christensen, Søren Tvorup & Pedersen, Stine Helene Falsig, 2009, In: Journal of Cell Biology. 185, 1, p. 163-76 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2008
  23. Published

    Cell volume regulation: physiology and pathophysiology

    Lambert, Ian Henry, Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2008, In: Acta Physiologica (Print Edition). 194, 4, p. 255-82 27 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Chapter 10 the primary cilium coordinates signaling pathways in cell cycle control and migration during development and tissue repair

    Christensen, Søren Tvorup, Pedersen, Stine Helene Falsig, Satir, P., Veland, I. R. & Schneider, L., 2008, In: Current Topics in Developmental Biology. 85, p. 261-301 40 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    H-ras transformation sensitizes volume-activated anion channels and increases migratory activity of NIH3T3 fibroblasts.

    Schneider, L., Klausen, T. K., Stock, C., Mally, S., Christensen, Søren Tvorup, Pedersen, Stine Helene Falsig, Hoffmann, E. K. & Schwab, A., 2008, In: Pflügers Archiv: European Journal of Physiology. 455, 6, p. 1055-62 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Osmotic cell shrinkage activates ezrin/radixin/moesin (ERM) proteins: activation mechanisms and physiological implications

    Rasmussen, M., Alexander, R. T., Darborg, B. V., Møbjerg, Nadja, Hoffmann, E. K., Kapus , A. & Pedersen, Stine Helene Falsig, 2008, In: American Journal of Physiology: Cell Physiology. 294, 1, p. C197-C212 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2007
  28. Published

    Cell cycle-dependent activity of the volume- and Ca2+-activated anion currents in Ehrlich lettre ascites cells.

    Klausen, T. K., Bergdahl, A., Christophersen, P., Pedersen, Stine Helene Falsig & Hoffmann, E. K., 2007, In: Journal of Cellular Physiology. 210, 3, p. 831-42 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Induction of group VIA phospholipase A2 activity during in vitro ischemia in C2C12 myotubes is associated with changes in the level of its splice variants.

    Poulsen, K. A., Pedersen, Stine Helene Falsig, Kolko, M. & Lambert, Ian Henry, 2007, In: American Journal of Physiology: Cell Physiology. 293, 5, p. C1605-15

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    NHE1 inhibition by amiloride- and benzoylguanidine-type compounds. Inhibitor binding loci deduced from chimeras of NHE1 homologues with endogenous differences in inhibitor sensitivity.

    Pedersen, Stine Helene Falsig, King, S. A., Nygaard, E. B., Rigor, R. R. & Cala, P. M., 2007, In: Journal of Biological Chemistry. 282, 27, p. 19716-27 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Roles of Na+/H+ exchange in regulation of p38 mitogen-activated protein kinase activity and cell death after chemical anoxia in NIH3T3 fibroblasts.

    Rentsch, M. L., Ossum, C. G., Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2007, In: Pflügers Archiv: European Journal of Physiology. 454, 4, p. 649-62 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Shrinkage insensitivity of NKCC1 in myosin II-depleted cytoplasts from Ehrlich ascites tumor cells.

    Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2007, In: American Journal of Physiology: Cell Physiology. 292, 5, p. C1854-66

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    The Na+/H+ exchanger, NHE1, differentially regulates mitogen-activated protein kinase subfamilies after osmotic shrinkage in Ehrlich Lettre Ascites cells.

    Pedersen, Stine Helene Falsig, Rasmussen, M., Darborg, B. V., Nylandsted, J. & Hoffmann, E. K., 2007, In: Cellular Physiology and Biochemistry. 20, 6, p. 735-50 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Transient receptor potential channels in mechanosensing and cell volume regulation.

    Pedersen, Stine Helene Falsig & Nilius, B., 2007, In: Methods in Enzymology. 428, p. 183-207 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. 2006
  36. Published

    12th Acta Physiologica International Symposium "cell volume control in health and disease.".

    Hoffmann, E. K., Lambert, Ian Henry & Pedersen, Stine Helene Falsig, 2006, In: Acta Physiologica (Print Edition). 187, 1-2, p. 1-3 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Activation of PLA2 isoforms by cell swelling and ischaemia/hypoxia

    Lambert, Ian Henry, Pedersen, Stine Helene Falsig & Poulsen, K. A., 2006, In: Acta Physiologica (Print Edition). 187, 1-2, p. 75-85

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Cholesterol modulates the volume-regulated anion current in Ehrlich-Lettre ascites cells via effects on Rho and F-actin.

    Klausen, T. K., Hougaard, C., Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2006, In: American Journal of Physiology: Cell Physiology. 291, 4, p. C757-71

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Effects of chemical anoxia on NHE1, p38 MAPK, p53, Akt and ERM proteins in NIH3T3 fibroblasts: evidence for a role of NHE1 upstream of p38 MAPK

    Rentsch, M. L., Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2006, In: The FASEB Journal. 5, p. A1158

    Research output: Contribution to journalConference abstract in journalResearch

  40. Published

    Multiple PLA2 isoforms regulate taurine release in NIH3T3 mouse fibroblasts.

    Lambert, Ian Henry & Pedersen, Stine Helene Falsig, 2006, In: Advances in Experimental Medicine and Biology. 583, p. 99-108 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Physiology and pathophysiology of Na+/H+ exchange and Na+-K+-2Cl- cotransport in the heart, brain, and blood

    Pedersen, Stine Helene Falsig, O´Donnell, M. E., Anderson, S. E. & Cala, P. M., 2006, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 291, 1, p. R1-R25

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Regulation of mitogen-activated protein kinase pathways by the plasma membrane Na+/H+ exchanger, NHE1.

    Pedersen, Stine Helene Falsig, Darborg, B. V., Rentsch, M. L. & Rasmussen, M., 2006, In: Archives of Biochemistry and Biophysics. 462, 2, p. 195-201 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Roles of phospholipase A2 isoforms in swelling- and melittin-induced arachidonic acid release and taurine efflux in NIH3T3 fibroblasts.

    Pedersen, Stine Helene Falsig, Poulsen, K. A. & Lambert, Ian Henry, 2006, In: American Journal of Physiology: Cell Physiology. 291, 6, p. C 1286-1296

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Sensors and signal transduction pathways in vertebrate cell volume regulation.

    Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2006, In: Contributions to Nephrology. 152, p. 54-104 50 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    The Na+/H+ exchanger NHE1 in stress-induced signal transduction: implications for cell proliferation and cell death.

    Pedersen, Stine Helene Falsig, 2006, In: Pflügers Archiv: European Journal of Physiology. 452, 3, p. 249-59 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. 2005
  47. Published

    Causal relationship between NHE1, NKCC1, MAPKs and ERM proteins after osmotic shrinkage in Ehrlich Lettremouse ascites tumor cells.

    Darborg, B., Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2005, In: The FASEB Journal. 5, p. A1155

    Research output: Contribution to journalConference articleResearchpeer-review

  48. Published

    TRP channels: an overview.

    Pedersen, Stine Helene Falsig, Owsianik, G. & Nilius, B., 2005, In: Cell Calcium. 38, 3-4, p. 233-52 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Two distinct domains involved in amiloride inhibition of the Na+/H+Exchanger, NHE1.

    King, S. A., Pedersen, Stine Helene Falsig & Cala, P. M., 2005, In: FASEB Journal. Vol. 19 (5), p. A1585

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. 2004
  51. Published

    A novel NHE1 from red blood cells of the winter flounder: regulation by multiple signaling pathways.

    Pedersen, Stine Helene Falsig, 2004, In: Advances in Experimental Medicine and Biology. 559, p. 89-98 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Comparative biology of the ubiquitous Na+/H+ exchanger, NHE1: lessons from erythrocytes.

    Pedersen, Stine Helene Falsig & Cala, P. M., 2004, In: Journal of experimental zoology. Part A, Comparative experimental biology. 301, 7, p. 569-78 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Effectors and signaling events activated by cell shrinkage in ehrlich ascites tumor cells: implications for cell proliferation and programmed cell death.

    Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2004, In: Advances in Experimental Medicine and Biology. 559, p. 169-78 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Effectors and signalling events activated by cell shrinkage in Ehrlich ascites tumor cells: implication for cell proliferation and programmed cell death

    Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2004, Int. Cell Volume and signal transduction. New York: Kluwer/Plenum Publishers, p. 1-10

    Research output: Chapter in Book/Report/Conference proceedingReport chapterResearch

  55. Published

    Heat shock protein 70 inhibits shrinkage-induced programmed cell death via mechanisms independent of effects on cell volume-regulatory membrane transport proteins.

    Nylandsted, J., Jäättelä, M., Hoffmann, E. K. & Pedersen, Stine Helene Falsig, 2004, In: Pflügers Archiv: European Journal of Physiology. 449, 2, p. 175-85 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Hsp-70 mediated protection of WEHI cells against hypertonic stress-induced programmed cell death by a mechanism independent of effects on volume-regulatory membrane transport proteins

    Pedersen, Stine Helene Falsig, Larsen, J. N., Hoffmann, E. K. & Jaattela, M., 2004, In: The FASEB Journal. 18 (5), p. A1284 suppl.s.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Regulation of the expression and subcellular localization of the taurine transporter TauT in mouse NIH3T3 fibroblasts

    Voss, J. W., Pedersen, Stine Helene Falsig, Christensen, Søren Tvorup & Lambert, Ian Henry, 2004, In: European Journal of Biochemistry. 271, p. 4646-4658

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Signal transduction mechanisms involved in the rgulation of NHE1 from Pseudopleuronectes Americanus red blood cells by osmotic shrinkage , ß-adrenergic stimuli, and calyculin A

    Pedersen, Stine Helene Falsig, Holt, M., King, S. A. & Cala, P. M., 2004, In: Bull. Mount Desert Island Biol. Lab. 43, p. 9-11

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 8742