Can a Charged Surfactant Unfold an Uncharged Protein?

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Can a Charged Surfactant Unfold an Uncharged Protein? / Højgaard, Casper; Sørensen, Henrik Vinther; Pedersen, Jan Skov; Winther, Jakob Rahr; Otzen, Daniel Erik.

In: Biophysical Journal, Vol. 115, No. 11, 2018, p. 2081-2086.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Højgaard, C, Sørensen, HV, Pedersen, JS, Winther, JR & Otzen, DE 2018, 'Can a Charged Surfactant Unfold an Uncharged Protein?', Biophysical Journal, vol. 115, no. 11, pp. 2081-2086. https://doi.org/10.1016/j.bpj.2018.10.022

APA

Højgaard, C., Sørensen, H. V., Pedersen, J. S., Winther, J. R., & Otzen, D. E. (2018). Can a Charged Surfactant Unfold an Uncharged Protein? Biophysical Journal, 115(11), 2081-2086. https://doi.org/10.1016/j.bpj.2018.10.022

Vancouver

Højgaard C, Sørensen HV, Pedersen JS, Winther JR, Otzen DE. Can a Charged Surfactant Unfold an Uncharged Protein? Biophysical Journal. 2018;115(11):2081-2086. https://doi.org/10.1016/j.bpj.2018.10.022

Author

Højgaard, Casper ; Sørensen, Henrik Vinther ; Pedersen, Jan Skov ; Winther, Jakob Rahr ; Otzen, Daniel Erik. / Can a Charged Surfactant Unfold an Uncharged Protein?. In: Biophysical Journal. 2018 ; Vol. 115, No. 11. pp. 2081-2086.

Bibtex

@article{f063d7efbc0e461b91b13c1957c72d88,
title = "Can a Charged Surfactant Unfold an Uncharged Protein?",
abstract = "Does sodium dodecyl sulfate (SDS) denature proteins through electrostatic SDS-protein interactions? We show that a protein completely lacking charged side chains is unfolded by SDS in a manner similar to charged proteins, revealing that formal protein charges are not required for SDS-induced protein unfolding or binding.",
author = "Casper H{\o}jgaard and S{\o}rensen, {Henrik Vinther} and Pedersen, {Jan Skov} and Winther, {Jakob Rahr} and Otzen, {Daniel Erik}",
year = "2018",
doi = "10.1016/j.bpj.2018.10.022",
language = "English",
volume = "115",
pages = "2081--2086",
journal = "Biophysical Journal",
issn = "0006-3495",
publisher = "Cell Press",
number = "11",

}

RIS

TY - JOUR

T1 - Can a Charged Surfactant Unfold an Uncharged Protein?

AU - Højgaard, Casper

AU - Sørensen, Henrik Vinther

AU - Pedersen, Jan Skov

AU - Winther, Jakob Rahr

AU - Otzen, Daniel Erik

PY - 2018

Y1 - 2018

N2 - Does sodium dodecyl sulfate (SDS) denature proteins through electrostatic SDS-protein interactions? We show that a protein completely lacking charged side chains is unfolded by SDS in a manner similar to charged proteins, revealing that formal protein charges are not required for SDS-induced protein unfolding or binding.

AB - Does sodium dodecyl sulfate (SDS) denature proteins through electrostatic SDS-protein interactions? We show that a protein completely lacking charged side chains is unfolded by SDS in a manner similar to charged proteins, revealing that formal protein charges are not required for SDS-induced protein unfolding or binding.

U2 - 10.1016/j.bpj.2018.10.022

DO - 10.1016/j.bpj.2018.10.022

M3 - Journal article

C2 - 30447995

AN - SCOPUS:85056473269

VL - 115

SP - 2081

EP - 2086

JO - Biophysical Journal

JF - Biophysical Journal

SN - 0006-3495

IS - 11

ER -

ID: 209704322