Johan Gotthardt Olsen
Assistant Professor, Guest Researcher
- 2024
- Published
Checkpoint activation by Spd1: a competition-based system relying on tandem disordered PCNA binding motifs
Olsen, Johan Gotthardt, Prestel, Andreas, Kassem, N., Broendum, S. S., Hossain, Mohammad Shamim, Simonsen, Signe, Grysbæk, M., Mortensen, J., Rytkjær, L. L., Haxholm, G. W., Marabini, R., Holmberg, Christian, Carr, A. M., Crehuet, R., Nielsen, Olaf & Kragelund, Birthe Brandt, 2024, In: Nucleic acids symposium series. 52, 4, p. 2030–2044 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The bacterial DNA sliding clamp, β-clamp: structure, interactions, dynamics and drug discovery
Simonsen, Signe, Søgaard, C. K., Olsen, Johan Gotthardt, Otterlei, M. & Kragelund, Birthe Brandt, 2024, In: Cellular and Molecular Life Sciences. 81, 1, 25 p., 245.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Assessment of models for calculating the hydrodynamic radius of intrinsically disordered proteins
Pesce, Francesco, Newcombe, Estella Anne, Seiffert, P., Tranchant, E. E., Olsen, Johan Gotthardt, Grace, C. R., Kragelund, Birthe Brandt & Lindorff-Larsen, Kresten, 2023, In: Biophysical Journal. 122, 2, p. 310-321 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comment on “Intrinsic protein disorder uncouples affinity from binding specificity”
Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2023, In: Protein Science. 32, 4, 2 p., e4602.Research output: Contribution to journal › Comment/debate › Research › peer-review
- 2022
- Published
Hovedbrud i udbrud
Olsen, Johan Gotthardt & Hendricks, Vincent F., 2022, 2. ed. København: Gad. 92 p.Research output: Book/Report › Book › Education
- 2021
- Published
Dynamic Na+/H+ exchanger 1 (NHE1) - calmodulin complexes of varying stoichiometry and structure regulate Ca2+-dependent NHE1 activation
Sjøgaard-Frich, Lise Margrethe, Prestel, Andreas, Pedersen, E. S., Severin, M., Kristensen, Kristian Kølby, Olsen, Johan Gotthardt, Kragelund, Birthe Brandt & Pedersen, Stine Helene Falsig, 2021, In: eLife. 10, 29 p., e60889.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On the specificity of protein-protein interactions in the context of disorder
Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2021, In: Biochemical Journal. 478, 11, p. 2035-2050 16 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Synergistic stabilization of a double mutant in chymotrypsin inhibitor 2 from a library screen in E. coli
Hamborg, L., Granata, D., Olsen, Johan Gotthardt, Roche, J. V., Pedersen, L. E., Nielsen, A. T., Lindorff-Larsen, Kresten & Teilum, Kaare, 2021, In: Communications Biology . 4, 9 p., 980.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Børnevenlig forklaring: Hvad er induktion og generaliseringer?
Hendricks, Vincent F. & Olsen, Johan Gotthardt, 15 Nov 2020, In: videnskab.dk.Research output: Contribution to journal › Contribution to newspaper - Newspaper article › Communication
- Published
Videnskabelig uvidenhed og usikkerhed forklaret til børn
Hendricks, Vincent F. & Olsen, Johan Gotthardt, 7 Nov 2020, In: videnskab.dk.Research output: Contribution to journal › Contribution to newspaper - Feature article › Communication
- Published
Hovedbrud: Naturvidenskab og filosofi
Hendricks, Vincent F. & Olsen, Johan Gotthardt, 29 Sep 2020, Gad. 233 p.Research output: Book/Report › Book › Education
- Published
Interactions by Disorder - A Matter of Context
Bugge, K., Brakti, Inna, Fernandes, Catarina, Dreier, J. E., Lundsgaard, J. E., Olsen, Johan Gotthardt, Skriver, Karen & Kragelund, Birthe Brandt, 2020, In: Frontiers in Molecular Biosciences. 7, 16 p., 110.Research output: Contribution to journal › Review › Research › peer-review
- 2018
- Published
Structure of radical-induced cell death1 hub domain reveals a common αα-scaffold for disorder in transcriptional networks
Bugge, K. Ø., Staby, L., Kemplen, K. R., O'Shea, Charlotte, Bendsen, S. K., Jensen, M. K., Olsen, Johan Gotthardt, Skriver, Karen & Kragelund, Birthe Brandt, 2018, In: Structure. 26, 5, p. 734-746 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Behaviour of intrinsically disordered proteins in protein-protein complexes with an emphasis on fuzziness
Olsen, Johan Gotthardt, Teilum, Kaare & Kragelund, Birthe Brandt, Sep 2017, In: Cellular and Molecular Life Sciences. 74, 17, p. 3175-3183 9 p.Research output: Contribution to journal › Review › Research › peer-review
- 2016
- Published
A combined computational and structural model of the full-length human prolactin receptor
Bugge, K. Ø., Papaleo, E., Haxholm, G. W., Hopper, J. T. S., Robinson, C. V., Olsen, Johan Gotthardt, Lindorff-Larsen, Kresten & Kragelund, Birthe Brandt, 2016, In: Nature Communications. 7, 11 p., 11578.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Computational redesign of thioredoxin is hypersensitive towards minor conformational changes in the backbone template
Johansson, Kristoffer Enøe, Johansen, Nicolai Tidemand, Christensen, S., Horowitz, S., Bardwell, J. C. A., Olsen, Johan Gotthardt, Willemoës, Martin, Lindorff-Larsen, Kresten, Ferkinghoff-Borg, J., Hamelryck, Thomas Wim & Winther, Jakob R., 2016, In: Journal of Molecular Biology. 428, 21, p. 4361-4377 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Globular and disordered-the non-identical twins in protein-protein interactions
Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2015, In: Frontiers in Bioscience. 2, 6 p., 40.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intrinsically disordered cytoplasmic domains of two cytokine receptors mediate conserved interactions with membranes
Haxholm, G. W., Nikolajsen, L. F., Olsen, Johan Gotthardt, Fredsted, J., Larsen, F. H., Goffin, V., Pedersen, Stine Helene Falsig, Brooks, A. J., Waters, M. J. & Kragelund, Birthe Brandt, 2015, In: Biochemical Journal. 468, 3, p. 495-506 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Who climbs the tryptophan ladder? On the structure and function of the WSXWS motif in cytokine receptors and thrombospondin repeats
Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2014, In: Cytokine & Growth Factor Reviews. 25, 3, p. 337-341 5 p.Research output: Contribution to journal › Review › Research › peer-review
- 2012
- Published
The WSXWS motif in cytokine receptors is a molecular switch involved in receptor activation: insight from structures of the prolactin receptor
Dagil, Robert, Knudsen, M. J., Olsen, Johan Gotthardt, O'Shea, Charlotte, Franzmann, M., Goffin, V., Teilum, Kaare, Breinholt, J. & Kragelund, Birthe Brandt, 2012, In: Structure. 20, 2, p. 270-282 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Development of prolactin receptor antagonists with reduced pH-dependence of receptor binding.
Hansen, M. J. K., Olsen, Johan Gotthardt, Bernichtein, S., O'Shea, Charlotte, Sigurskjold, B. W., Goffin, V. & Kragelund, Birthe Brandt, 2011, In: Journal of Molecular Recognition. 24, 4, p. 533-547 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein stability, flexibility and function
Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2011, In: B B A - Proteins and Proteomics. 1814, 8, p. 969-76 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Streptococcal pyogenic exotoxin B (SpeB) boosts the contact system via binding of a-1 antitrypsin
Meinert Niclasen, L., Olsen, Johan Gotthardt, Dagil, Robert, Qing, Z., Sørensen, O. E. & Kragelund, Birthe Brandt, 2011, In: Biochemical Journal. 434, 1, p. 123-32 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Functional aspects of protein flexibility
Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2009, In: Cellular and Molecular Life Sciences. 66, 14, p. 2231-47 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure of the Mature Streptococcal Cysteine Protease Exotoxin mSpeB in Its Active Dimeric Form
Olsen, Johan Gotthardt, Dagil, Robert, Niclasen, L. M., Sørensen, O. E. & Kragelund, Birthe Brandt, 2009, In: Journal of Molecular Biology. 393, 3, p. 693-703 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2001
- Published
Β-Ketoacyl - (Acyl Carrier Protein) Synthase I of Escherichia coli: Aspects of the Condensation Mechanism Revealed by Analyses of Mutations in the Active Site Pocket
McGuire, K. A., Siggaard-Andersen, M., Bangera, M. G., Olsen, Johan Gotthardt & von Wettstein, Penny, 2001, In: Biochemistry. 40(33), p. 9836-9845Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fatty Acid Biosynthesis: Fatty Acid Synthase. Molecular aspects of β-ketoacyl synthase (KAS) catalysis.
von Wettstein, Penny, Olsen, Johan Gotthardt, McGuire, K. A. & Larsen, Sine, 2001, In: Biochemical Society. 28, p. 601-607Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structures of β-Ketoacyl-Acyl Carrier Protein Synthase I Complexed with Fatty Acids Elucidate its Catalytic Machinery
Olsen, Johan Gotthardt, Kadziola, A., von Wettstein-Knowles, P., Siggaard-Andersen, M. & Larsen, Sine, 2001, In: Structure. 9, p. 233-243Research output: Contribution to journal › Journal article › Research › peer-review
- 2000
- Published
Molecular aspects of beta-ketoacyl synthase (KAS) catalysis
von Wettstein, Penny, Olsen, Johan Gotthardt, Mcguire, K. A. & Larsen, Sine, 2000, In: Biochem. Soc. Trans.. 28, p. 601-607Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
- Published
The X-ray crystal structure of β-ketoacyl [acyl carrier protein] sinthase I
Olsen, Johan Gotthardt, Kadziola, A., Wettstein-Knowles, P. V., Siggaard-Andersen, M., Lindquist, Y. & Larsen, Sine, 1999, In: FEBS Letters. 460, p. 46-52Research output: Contribution to journal › Journal article › Research › peer-review
- 1998
- Published
Defining the functions of highly conserved residues in beta-ketoacyl-ACP synthases
Siggaard-Andersen, M., Bangera, G., Olsen, Johan Gotthardt & von Wettstein, Penny, 1998, Advances in Plant Lipid Research. Spain: Universidad de Sevilla, p. 67-70Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
ID: 6186
Most downloads
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276
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A combined computational and structural model of the full-length human prolactin receptor
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
233
downloads
Computational redesign of thioredoxin is hypersensitive towards minor conformational changes in the backbone template
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
193
downloads
Behaviour of intrinsically disordered proteins in protein-protein complexes with an emphasis on fuzziness
Research output: Contribution to journal › Review › Research › peer-review
Published