Johan Gotthardt Olsen

Johan Gotthardt Olsen

Assistant Professor, Guest Researcher

Member of:


    1. 2024
    2. Published

      Checkpoint activation by Spd1: a competition-based system relying on tandem disordered PCNA binding motifs

      Olsen, Johan Gotthardt, Prestel, Andreas, Kassem, N., Broendum, S. S., Hossain, Mohammad Shamim, Simonsen, Signe, Grysbæk, M., Mortensen, J., Rytkjær, L. L., Haxholm, G. W., Marabini, R., Holmberg, Christian, Carr, A. M., Crehuet, R., Nielsen, Olaf & Kragelund, Birthe Brandt, 2024, In: Nucleic acids symposium series. 52, 4, p. 2030–2044 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      The bacterial DNA sliding clamp, β-clamp: structure, interactions, dynamics and drug discovery

      Simonsen, Signe, Søgaard, C. K., Olsen, Johan Gotthardt, Otterlei, M. & Kragelund, Birthe Brandt, 2024, In: Cellular and Molecular Life Sciences. 81, 1, 25 p., 245.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. 2023
    5. Published

      Assessment of models for calculating the hydrodynamic radius of intrinsically disordered proteins

      Pesce, Francesco, Newcombe, Estella Anne, Seiffert, P., Tranchant, E. E., Olsen, Johan Gotthardt, Grace, C. R., Kragelund, Birthe Brandt & Lindorff-Larsen, Kresten, 2023, In: Biophysical Journal. 122, 2, p. 310-321 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Comment on “Intrinsic protein disorder uncouples affinity from binding specificity

      Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2023, In: Protein Science. 32, 4, 2 p., e4602.

      Research output: Contribution to journalComment/debateResearchpeer-review

    7. 2022
    8. Published

      Hovedbrud i udbrud

      Olsen, Johan Gotthardt & Hendricks, Vincent F., 2022, 2. ed. København: Gad. 92 p.

      Research output: Book/ReportBookEducation

    9. 2021
    10. Published
    11. Published

      On the specificity of protein-protein interactions in the context of disorder

      Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2021, In: Biochemical Journal. 478, 11, p. 2035-2050 16 p.

      Research output: Contribution to journalReviewResearchpeer-review

    12. Published

      Synergistic stabilization of a double mutant in chymotrypsin inhibitor 2 from a library screen in E. coli

      Hamborg, L., Granata, D., Olsen, Johan Gotthardt, Roche, J. V., Pedersen, L. E., Nielsen, A. T., Lindorff-Larsen, Kresten & Teilum, Kaare, 2021, In: Communications Biology . 4, 9 p., 980.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. 2020
    14. Published

      Børnevenlig forklaring: Hvad er induktion og generaliseringer?

      Hendricks, Vincent F. & Olsen, Johan Gotthardt, 15 Nov 2020, In: videnskab.dk.

      Research output: Contribution to journalContribution to newspaper - Newspaper articleCommunication

    15. Published

      Videnskabelig uvidenhed og usikkerhed forklaret til børn

      Hendricks, Vincent F. & Olsen, Johan Gotthardt, 7 Nov 2020, In: videnskab.dk.

      Research output: Contribution to journalContribution to newspaper - Feature articleCommunication

    16. Published

      Hovedbrud: Naturvidenskab og filosofi

      Hendricks, Vincent F. & Olsen, Johan Gotthardt, 29 Sep 2020, Gad. 233 p.

      Research output: Book/ReportBookEducation

    17. Published

      Interactions by Disorder - A Matter of Context

      Bugge, K., Brakti, Inna, Fernandes, Catarina, Dreier, J. E., Lundsgaard, J. E., Olsen, Johan Gotthardt, Skriver, Karen & Kragelund, Birthe Brandt, 2020, In: Frontiers in Molecular Biosciences. 7, 16 p., 110.

      Research output: Contribution to journalReviewResearchpeer-review

    18. 2018
    19. Published

      Structure of radical-induced cell death1 hub domain reveals a common αα-scaffold for disorder in transcriptional networks

      Bugge, K. Ø., Staby, L., Kemplen, K. R., O'Shea, Charlotte, Bendsen, S. K., Jensen, M. K., Olsen, Johan Gotthardt, Skriver, Karen & Kragelund, Birthe Brandt, 2018, In: Structure. 26, 5, p. 734-746 21 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. 2017
    21. Published

      Behaviour of intrinsically disordered proteins in protein-protein complexes with an emphasis on fuzziness

      Olsen, Johan Gotthardt, Teilum, Kaare & Kragelund, Birthe Brandt, Sep 2017, In: Cellular and Molecular Life Sciences. 74, 17, p. 3175-3183 9 p.

      Research output: Contribution to journalReviewResearchpeer-review

    22. 2016
    23. Published

      A combined computational and structural model of the full-length human prolactin receptor

      Bugge, K. Ø., Papaleo, E., Haxholm, G. W., Hopper, J. T. S., Robinson, C. V., Olsen, Johan Gotthardt, Lindorff-Larsen, Kresten & Kragelund, Birthe Brandt, 2016, In: Nature Communications. 7, 11 p., 11578.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Computational redesign of thioredoxin is hypersensitive towards minor conformational changes in the backbone template

      Johansson, Kristoffer Enøe, Johansen, Nicolai Tidemand, Christensen, S., Horowitz, S., Bardwell, J. C. A., Olsen, Johan Gotthardt, Willemoës, Martin, Lindorff-Larsen, Kresten, Ferkinghoff-Borg, J., Hamelryck, Thomas Wim & Winther, Jakob R., 2016, In: Journal of Molecular Biology. 428, 21, p. 4361-4377 17 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. 2015
    26. Published

      Globular and disordered-the non-identical twins in protein-protein interactions

      Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2015, In: Frontiers in Bioscience. 2, 6 p., 40.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      Intrinsically disordered cytoplasmic domains of two cytokine receptors mediate conserved interactions with membranes

      Haxholm, G. W., Nikolajsen, L. F., Olsen, Johan Gotthardt, Fredsted, J., Larsen, F. H., Goffin, V., Pedersen, Stine Helene Falsig, Brooks, A. J., Waters, M. J. & Kragelund, Birthe Brandt, 2015, In: Biochemical Journal. 468, 3, p. 495-506 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. 2014
    29. Published

      Who climbs the tryptophan ladder? On the structure and function of the WSXWS motif in cytokine receptors and thrombospondin repeats

      Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2014, In: Cytokine & Growth Factor Reviews. 25, 3, p. 337-341 5 p.

      Research output: Contribution to journalReviewResearchpeer-review

    30. 2012
    31. Published

      The WSXWS motif in cytokine receptors is a molecular switch involved in receptor activation: insight from structures of the prolactin receptor

      Dagil, Robert, Knudsen, M. J., Olsen, Johan Gotthardt, O'Shea, Charlotte, Franzmann, M., Goffin, V., Teilum, Kaare, Breinholt, J. & Kragelund, Birthe Brandt, 2012, In: Structure. 20, 2, p. 270-282 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. 2011
    33. Published

      Development of prolactin receptor antagonists with reduced pH-dependence of receptor binding.

      Hansen, M. J. K., Olsen, Johan Gotthardt, Bernichtein, S., O'Shea, Charlotte, Sigurskjold, B. W., Goffin, V. & Kragelund, Birthe Brandt, 2011, In: Journal of Molecular Recognition. 24, 4, p. 533-547 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    34. Published

      Protein stability, flexibility and function

      Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2011, In: B B A - Proteins and Proteomics. 1814, 8, p. 969-76 8 p.

      Research output: Contribution to journalReviewResearchpeer-review

    35. Published

      Streptococcal pyogenic exotoxin B (SpeB) boosts the contact system via binding of a-1 antitrypsin

      Meinert Niclasen, L., Olsen, Johan Gotthardt, Dagil, Robert, Qing, Z., Sørensen, O. E. & Kragelund, Birthe Brandt, 2011, In: Biochemical Journal. 434, 1, p. 123-32 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    36. 2009
    37. Published

      Functional aspects of protein flexibility

      Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2009, In: Cellular and Molecular Life Sciences. 66, 14, p. 2231-47 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    38. Published

      Structure of the Mature Streptococcal Cysteine Protease Exotoxin mSpeB in Its Active Dimeric Form

      Olsen, Johan Gotthardt, Dagil, Robert, Niclasen, L. M., Sørensen, O. E. & Kragelund, Birthe Brandt, 2009, In: Journal of Molecular Biology. 393, 3, p. 693-703 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

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