Robin Andersson
Associate Professor
Computational and RNA Biology
Ole Maaløes Vej 5
2200 København N.
- 2024
- Published
MYC activity at enhancers drives prognostic transcriptional programs through an epigenetic switch
Jakobsen, S. T., Jensen, R. A. M., Madsen, M. S., Ravnsborg, T., Vaagenso, C. S., Siersbæk, M. S., Einarsson, H., Andersson, Robin, Jensen, O. N. & Siersbæk, R., 2024, In: Nature Genetics. 56, p. 663–674 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Pooled analysis of frontal lobe transcriptomic data identifies key mitophagy gene changes in Alzheimer's disease brain
Mei, T., Li, Yuan, Orduña Dolado, A., Li, Zhiquan, Andersson, Robin, Berliocchi, Laura & Rasmussen, Lene Juel, 2023, In: Frontiers in Aging Neuroscience. 15, 14 p., 1101216.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Symmetric inheritance of parental histones governs epigenome maintenance and embryonic stem cell identity
Wenger, Alice, Biran, Alva Ada, Alcaraz, N., Redó-Riveiro, A., Sell, Annika Charlotte, Krautz, Robert, Flury, Valentin, Reveron-Gomez, Nazaret, Solis-Mezarino, V., Völker-Albert, M., Imhof, A., Andersson, Robin, Brickman, Joshua Mark & Groth, Anja, 2023, In: Nature Genetics. 55, 9, p. 1567-1578 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcription factor expression is the main determinant of variability in gene co-activity
van Duin, Lucas, Krautz, Robert, Rennie, Sarah & Andersson, Robin, 2023, In: Molecular Systems Biology. 19, 7, 17 p., e11392.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transfer learning identifies sequence determinants of cell-type specific regulatory element accessibility
Salvatore, Marco, Horlacher, M., Marsico, A., Winther, Ole & Andersson, Robin, 2023, In: NAR Genomics and Bioinformatics. 5, 2, 10 p., 026.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Current challenges in understanding the role of enhancers in disease
Zaugg, J. B., Sahlén, P., Andersson, Robin, Alberich-Jorda, M., de Laat, W., Deplancke, B., Ferrer, J., Mandrup, S., Natoli, G., Plewczynski, D., Rada-Iglesias, A. & Spicuglia, S., 2022, In: Nature Structural and Molecular Biology. 29, 12, p. 1148-1158 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endogenous retroviruses co-opted as divergently transcribed regulatory elements shape the regulatory landscape of embryonic stem cells
Bakoulis, Stylianos, Krautz, Robert, Alcaraz, N., Salvatore, Marco & Andersson, Robin, 2022, In: Nucleic acids symposium series. 50, 4, p. 2111-2127 17 p., 088.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Methods for fighting emerging pathogens
Alcantara, L. C. J., Amenga-Etego, L., Andersson, Robin, Bhaumik, M., Choi, Y. K., Decaluwe, H., Geoghegan, J., Haagmans, B. L., López, S., Mukhtar, M. M., Nelwan, E., Rahal, E. A., Sato, K., Sklan, E. H. & Fang, Y. S. C., 2022, In: Nature Methods. 19, 4, p. 395-397 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Promoter sequence and architecture determine expression variability and confer robustness to genetic variants
Einarsson, H., Salvatore, Marco, Vaagenso, C., Alcaraz, N., Lange, Jette Bornholdt, Rennie, Sarah & Andersson, Robin, 2022, In: eLife. 2022, 36 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
- Published
- 2021
- Published
Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network
Grapotte, M., Saraswat, M., Bessière, C., Menichelli, C., Ramilowski, J. A., Severin, J., Hayashizaki, Y., Itoh, M., Tagami, M., Murata, M., Kojima-Ishiyama, M., Noma, S., Noguchi, S., Kasukawa, T., Hasegawa, A., Suzuki, H., Nishiyori-Sueki, H., Frith, M. C., Abugessaisa, I., Aitken, S. & 31 others, , 2021, In: Nature Communications. 12, 18 p., 3297.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide and sister chromatid-resolved profiling of protein occupancy in replicated chromatin with ChOR-seq and SCAR-seq
Petryk, N., Reveron-Gomez, Nazaret, González-Aguilera, C., Dalby, M., Andersson, Robin & Groth, Anja, 2021, In: Nature Protocols. 16, p. 4446-4493Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Principles of mRNA targeting via the Arabidopsis m6A-binding protein ECT2
Arribas Hernandez, Laura, Rennie, Sarah, Köster, T., Porcelli, C., Lewinski, M., Staiger, D., Andersson, Robin & Brodersen, Peter, 2021, In: eLife. 10, 33 p., e72375.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The YTHDF proteins ECT2 and ECT3 bind largely overlapping target sets and influence target mRNA abundance, not alternative polyadenylation
Arribas Hernandez, Laura, Rennie, Sarah, Schon, M., Porcelli, C., Enugutti, B., Andersson, Robin, Nodine, M. D. & Brodersen, Peter, 2021, In: eLife. 10, 27 p., e72377.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
hyperTRIBER: a flexible R package for the analysis of differential RNA editing
Rennie, Sarah, Magnusson, D. H. & Andersson, Robin, 2021, 12 p.Research output: Working paper › Preprint
- 2020
- Published
Comparative transcriptomics of primary cells in vertebrates
Alam, T., Agrawal, S., Severin, J., Young, R. S., Andersson, R., Arner, E., Hasegawa, A., Lizio, M., Ramilowski, J. A., Abugessaisa, I., Ishizu, Y., Noma, S., Tarui, H., Taylor, M. S., Lassmann, T., Itoh, M., Kasukawa, T., Kawaji, H., Marchionni, L., Sheng, G. & 5 others, , 2020, In: Genome Research. 30, 7, p. 951-961 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determinants of enhancer and promoter activities of regulatory elements
Andersson, Robin & Sandelin, Albin Gustav, 2020, In: Nature Reviews Genetics. 21, 2, p. 71-87 17 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The Transcriptional Network That Controls Growth Arrest and Macrophage Differentiation in the Human Myeloid Leukemia Cell Line THP-1
Gazova, I., Lefevre, L., Bush, S. J., Clohisey, S., Arner, E., de Hoon, M., Severin, J., van Duin, Lucas, Andersson, Robin, Lengeling, A., Hume, D. A. & Summers, K. M., 2020, In: Frontiers in Cell and Developmental Biology. 8, 21 p., 498.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
CAGEfightR: analysis of 5'-end data using R/Bioconductor
Thodberg, Malte, Thieffry, A., Vitting-Seerup, K., Andersson, Robin & Sandelin, Albin Gustav, 2019, In: BMC Bioinformatics. 20, 13 p., 487.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells
Agrawal-Singh, S., Lerdrup, Mads, Gomes, A. R., van de Werken, H. J. G., Johansen, Jens Vilstrup, Andersson, Robin, Sandelin, Albin Gustav, Helin, K. & Hansen, K., 2019, In: eLife. 8, p. 1-32 32 p., e40364.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
- Published
Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies
Boyd, M., Thodberg, M., Vitezic, M., Lange, J. B., Vitting-Seerup, K., Chen, Y., Coskun, M., Li, Y., Lo, B. Z. S., Klausen, P., Schweiger, P., Pedersen, A. G., Rapin, N. P. J-P., Skovgaard, K., Dahlgaard, K., Andersson, R., Terkelsen, T. B., Lilje, B., Troelsen, J. T., Petersen, A. M. & 7 others, , 2018, In: Nature Communications. 9, 19 p., 1661.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes
Grarup, Niels, Moltke, Ida, Lepola, Mette Andersen, Dalby, M., Vitting-Seerup, K., Kern, T. S., Mahendran, Y., Jørsboe, E., Larsen, C. V. L., Dahl-Petersen, I. K., Gilly, A., Suveges, D., Dedoussis, G., Zeggini, E., Pedersen, Oluf Borbye, Andersson, Robin, Bjerregaard, P., Jørgensen, M. E., Albrechtsen, Anders & Hansen, Torben, 2018, In: Nature Genetics. 50, 2, p. 172-174 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MCM2 promotes symmetric inheritance of modified histones during DNA replication
Petryk, N., Dalby, M., Wenger, Alice, Stromme, C. B., Strandsby, A., Andersson, Robin & Groth, Anja, 2018, In: Science. 361, 6409, p. 1389-1392 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease
Baillie, J. K., Bretherick, A., Haley, C. S., Clohisey, S., Gray, A., Neyton, L. P. A., Barrett, J., Stahl, E. A., Tenesa, A., Andersson, R., Brown, J. B., Faulkner, G. J., Lizio, M., Schaefer, U., Daub, C., Itoh, M., Kondo, N., Lassmann, T., Kawai, J., Mole, D. & 14 others, , 2018, In: PLoS Computational Biology. 14, 3, 24 p., e1005934.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The GBAF chromatin remodeling complex binds H3K27ac and mediates enhancer transcription
Jefimov, K., Alcaraz, N., Kloet, S. L., Värv, S., Sakya, S. A., Vaagenso, C., Vermeulen, M., Aasland, R. & Andersson, Robin, 2018, 31 p.Research output: Working paper › Preprint
- Published
The RNA exosome contributes to gene expression regulation during stem cell differentiation
Llinares, M. L., Karadoulama, Evdoxia, Chen, Y., Wojenski, L. A., Villafano, G. J., Lange, Jette Bornholdt, Andersson, Robin, Core, L., Sandelin, Albin Gustav & Jensen, T. H., 2018, In: Nucleic Acids Research. 46, 21, p. 11502-11513Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcription start site analysis reveals widespread divergent transcription in D. melanogaster and core promoter-encoded enhancer activities
Rennie, Sarah, Dalby, M., Lloret-Llinares, M., Bakoulis, Stylianos, Dalager Vaagensø, C., Jensen, T. H. & Andersson, Robin, 2018, In: Nucleic Acids Research. 46, 11, p. 5455-5469 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactions
Rennie, Sarah, Dalby, M., van Duin, Lucas & Andersson, Robin, 2018, In: Nature Communications. 9, 16 p., 487.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Identification of gene transcription start sites and enhancers responding to pulmonary carbon nanotube exposure in Vivo
Lange, Jette Bornholdt, Saber, A. T., Lilje, B., Boyd, M., Jørgensen, M., Chen, Y., Vitezic, M., Jacobsen, N. R., Poulsen, S. S., Berthing, T., Bressendorff, Simon, Vitting-Seerup, K., Andersson, Robin, Hougaard, K. S., Yauk, C. L., Halappanavar, S., Wallin, E. H. R., Vogel, U. & Sandelin, Albin Gustav, 2017, In: A C S Nano. 11, 4, p. 3597-3613 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptional dynamics during human adipogenesis and its link to adipose morphology and distribution
Ehrlund, A., Mejhert, N., Björk, C., Andersson, Robin, Kulyté, A., Åström, G., Itoh, M., Kawaji, H., Lassmann, T., Daub, C. O., Carninci, P., Forrest, A. R. R., Hayashizaki, Y., Sandelin, Albin Gustav, Ingelsson, E., FANTOM Consortium, Rydén, M., Laurencikiene, J., Arner, P. & Arner, E., 2017, In: Diabetes. 66, 1, p. 218-230 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Update of the FANTOM web resource: high resolution transcriptome of diverse cell types in mammals
Lizio, M., Harshbarger, J., Abugessaisa, I., Noguchi, S., Kondo, A., Severin, J., Mungall, C., Arenillas, D., Mathelier, A., Medvedeva, Y. A., Lennartsson, A., Drabløs, F., Ramilowski, J. A., Rackham, O., Gough, J., Andersson, R., Sandelin, A. G., Ienasescu, H-I., Ono, H., Bono, H. & 5 others, , 2017, In: Nucleic Acids Research. 45, D1, p. D737-D743 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
On-the-fly selection of cell-specific enhancers, genes, miRNAs and proteins across the human body using SlideBase
Ienasescu, H., Li, K., Andersson, Robin, Vitezic, M., Rennie, Sarah, Chen, Y., Vitting-Seerup, K., Lagoni, E., Boyd, M., Lange, Jette Bornholdt, de Hoon, M. J. L., Kawaji, H., Lassmann, T., FANTOM Consortium, F. C., Hayashizaki, Y., Forrest, A. R. R., Carninci, P. & Sandelin, Albin Gustav, 2016, In: Database: The Journal of Biological Databases and Curation. 2016, 0, 10 p., baw144.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Principles for RNA metabolism and alternative transcription initiation within closely spaced promoters
Chen, Y., Pai, A. A., Herudek, J., Lubas, M., Meola, N., Järvelin, A. I., Andersson, Robin, Pelechano, V., Steinmetz, L. M., Jensen, T. H. & Sandelin, Albin Gustav, 2016, In: Nature Genetics. 48, 9, p. 984-994 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulating retrotransposon activity through the use of alternative transcription start sites
Persson, J., Steglich, B., Smialowska, A., Boyd, M., Lange, Jette Bornholdt, Andersson, Robin, Schurra, C., Arcangioli, B., Sandelin, Albin Gustav, Nielsen, Olaf & Ekwall, K., 2016, In: E M B O Reports. 17, 5, p. 753-768 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptome analysis of recurrently deregulated genes across multiple cancers identifies new pan-cancer biomarkers
Kaczkowski, B., Tanaka, Y., Kawaji, H., Sandelin, Albin Gustav, Andersson, Robin, Itoh, M., Lassmann, T., the FANTOM5 consortium, Hayashizaki, Y., Carninci, P. & Forrest, A. R. R., 2016, In: Cancer Research. 76, 2, p. 216-226Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
A unified architecture of transcriptional regulatory elements
Andersson, Robin, Sandelin, Albin Gustav & Danko, C. G., Aug 2015, In: Trends in Genetics. 31, 8, p. 426-433 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human gene promoters are intrinsically bidirectional
Andersson, Robin, Chen, Y., Core, L., Lis, J. T., Sandelin, Albin Gustav & Jensen, T. H., 2015, In: Molecular Cell. 60, 3, p. 346-347 2 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Promoter or enhancer, what's the difference? Deconstruction of established distinctions and presentation of a unifying model
Andersson, Robin, 2015, In: BioEssays. 37, 3, p. 314-323 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Remodeling of retrotransposon elements during epigenetic induction of adult visual cortical plasticity by HDAC inhibitors
Lennartsson, A., Arner, E., Fagiolini, M., Saxena, A., Andersson, Robin, Takahashi, H., Noro, Y., Sng, J., Sandelin, Albin Gustav, Hensch, T. K. & Carninci, P., 2015, In: Epigenetics & Chromatin. 8, 15 p., 55.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The constrained maximal expression level owing to haploidy shapes gene content on the mammalian X chromosome
Hurst, L. D., Ghanbarian, A. T., Forrest, A. R. R., Huminiecki, L., Rehli, M., Kenneth Baillie, J., de Hoon, M. J. L., Haberle, V., Lassmann, T., Kulakovskiy, I. V., Lizio, M., Itoh, M., Andersson, R., Mungall, C. J., Meehan, T. F., Schmeier, S., Bertin, N., Jørgensen, M., Dimont, E., Arner, E. & 243 others, , 2015, In: PLoS Biology. 13, 12, 48 p., e1002315.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The frequent evolutionary birth and death of functional promoters in mouse and human
Young, R. S., Hayashizaki, Y., Andersson, Robin, Sandelin, Albin Gustav, Kawaji, H., Itoh, M., Lassmann, T., Carninci, P., Bickmore, W. A., Forrest, A. R. & Taylor, M. S., 2015, In: Genome Research. 25, p. 1546-1557 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells
Arner, E., Daub, C. O., Vitting-Seerup, K., Andersson, R., Lilje, B., Drabløs, F., Lennartsson, A., Rönnerblad, M., Hrydziuszko, O., Vitezic, M., Freeman, T. C., Alhendi, A. M. N., Arner, P., Axton, R., Baillie, J. K., Beckhouse, A., Bodega, B., Briggs, J., Brombacher, F., Davis, M. & 89 others, , 2015, In: Science (New York, N.Y.). 347, 6225, p. 1010-1014 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
A promoter-level mammalian expression atlas
Forest, A. R. R., Kawaji, H., Rehli, M., Baillie, J. K., De Hoon, M. J. L., Haberle, V., Lassmann, T., Kulakovskiy, I. V., Lizio, M., Itoh, M., Andersson, R., Mungall, C. J., Meehan, T. F., Schmeier, S., Bertin, N., Jørgensen, M., Dimont, E., Arner, E., Schmidl, C., Schaefer, U. & 241 others, , 2014, In: Nature. 507, 7493, p. 462-470 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An atlas of active enhancers across human cell types and tissues
Andersson, R., Gebhard, C., Miguel-Escalada, I., Hoof, I., Lange, J. B., Boyd, M., Chen, Y., Zhao, X., Schmidl, C., Suzuki, T., Ntini, E., Arner, E., Valen, E., Li, K., Schwarzfischer, L., Glatz, D., Raithel, J., Lilje, B., Rapin, N., Bagger, F. O. & 30 others, , 2014, In: Nature. 507, 7493, p. 455-461 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of the DNA methylome and transcriptome in granulopoiesis reveal timed changes and dynamic enhancer methylation
Rönnerblad, M., Andersson, Robin, Olofsson, T., Douagi, I., Karimi, M., Lehmann, S., Hoof, I., de Hoon, M., Itoh, M., Nagao-Sato, S., Kawaji, H., Lassmann, T., Carninci, P., Hayashizaki, Y., Forrest, A. R. R., Sandelin, Albin Gustav, Ekwall, K., Arner, E. & Lennartsson, A., 2014, In: Blood. 123, 17Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CAGE-defined promoter regions of the genes implicated in Rett Syndrome
Vitezic, M., Bertin, N., Andersson, Robin, Lipovich, L., Kawaji, H., Lassmann, T., Sandelin, Albin Gustav, Heutink, P., Goldowitz, D., Ha, T., Zhang, P., Patrizi, A., Fagiolini, M., Forrest, A. R., Carninci, P. & Saxena, A., 2014, In: BMC Genomics. 15, 16 p., 1177.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deep transcriptome profiling of mammalian stem cells supports a regulatory role for retrotransposons in pluripotency maintenance
Fort, A., Hashimoto, K., Yamada, D., Salimullah, M., Keya, C. A., Saxena, A., Bonetti, A., Voineagu, I., Bertin, N., Kratz, A., Noro, Y., Wong, C-H., de Hoon, M., Andersson, R., Sandelin, A. G., Suzuki, H., Wei, C-L., Koseki, H., Hasegawa, Y., Forrest, A. R. R. & 2 others, , 2014, In: Nature Genetics. 46, 6, p. 558-566 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide nucleosome map and cytosine methylation levels of an ancient human genome
Pedersen, J. S., Valen, E., Velazquez, A. M. V., Parker, B. J., Rasmussen, M., Lindgreen, S., Lilje, B., Tobin, D. J., Kelly, T. K., Vang, S., Andersson, R., Jones, P. A., Hoover, C. A., Tikhonov, A., Prokhortchouk, E., Rubin, E. M., Sandelin, A. G., Gilbert, M. T. P., Krogh, A., Willerslev, E. & 1 others, , 2014, In: Genome Research. 24, 3, p. 454-466 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 32384007
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Identification of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2
Research output: Contribution to journal › Journal article › Research › peer-review
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1383
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Cancer associated epigenetic transitions identified by genome-wide histone methylation binding profiles in human colorectal cancer samples and paired normal mucosa
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1068
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A strand specific high resolution normalization method for chip-sequencing data employing multiple experimental control measurements.
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