Small RNA-Based Regulation of Bacterial Quorum Sensing and Biofilm Formation

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Standard

Small RNA-Based Regulation of Bacterial Quorum Sensing and Biofilm Formation. / Svenningsen, Sine Lo.

I: Microbiology Spectrum, Bind 6, Nr. 4, 2018.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Svenningsen, SL 2018, 'Small RNA-Based Regulation of Bacterial Quorum Sensing and Biofilm Formation', Microbiology Spectrum, bind 6, nr. 4. https://doi.org/10.1128/microbiolspec.RWR-0017-2018

APA

Svenningsen, S. L. (2018). Small RNA-Based Regulation of Bacterial Quorum Sensing and Biofilm Formation. Microbiology Spectrum, 6(4). https://doi.org/10.1128/microbiolspec.RWR-0017-2018

Vancouver

Svenningsen SL. Small RNA-Based Regulation of Bacterial Quorum Sensing and Biofilm Formation. Microbiology Spectrum. 2018;6(4). https://doi.org/10.1128/microbiolspec.RWR-0017-2018

Author

Svenningsen, Sine Lo. / Small RNA-Based Regulation of Bacterial Quorum Sensing and Biofilm Formation. I: Microbiology Spectrum. 2018 ; Bind 6, Nr. 4.

Bibtex

@article{96ff2f09314042f9a72c28ca96e22f70,
title = "Small RNA-Based Regulation of Bacterial Quorum Sensing and Biofilm Formation",
abstract = "Quorum sensing is a vital property of bacteria that enables community-wide coordination of collective behaviors. A key example of such a behavior is biofilm formation, in which groups of bacteria invest in synthesizing a protective, joint extracellular matrix. Quorum sensing involves the production, release, and subsequent detection of extracellular signaling molecules called autoinducers. The architecture of quorum-sensing signal transduction pathways is highly variable among different species of bacteria, but frequently involves posttranscriptional regulation carried out by small regulatory RNA molecules. This review illustrates the diverse roles small trans-acting regulatory RNAs can play, from constituting a network's core to auxiliary roles in adjusting the rate of autoinducer synthesis, mediating cross talk among different parts of a network, or integrating different regulatory inputs to trigger appropriate changes in gene expression. The emphasis is on describing how the study of small RNA-based regulation in quorum sensing and biofilm formation has uncovered new general properties or expanded our understanding of bacterial riboregulation.",
author = "Svenningsen, {Sine Lo}",
year = "2018",
doi = "10.1128/microbiolspec.RWR-0017-2018",
language = "English",
volume = "6",
journal = "Microbiology spectrum",
issn = "2165-0497",
publisher = "American Society for Microbiology",
number = "4",

}

RIS

TY - JOUR

T1 - Small RNA-Based Regulation of Bacterial Quorum Sensing and Biofilm Formation

AU - Svenningsen, Sine Lo

PY - 2018

Y1 - 2018

N2 - Quorum sensing is a vital property of bacteria that enables community-wide coordination of collective behaviors. A key example of such a behavior is biofilm formation, in which groups of bacteria invest in synthesizing a protective, joint extracellular matrix. Quorum sensing involves the production, release, and subsequent detection of extracellular signaling molecules called autoinducers. The architecture of quorum-sensing signal transduction pathways is highly variable among different species of bacteria, but frequently involves posttranscriptional regulation carried out by small regulatory RNA molecules. This review illustrates the diverse roles small trans-acting regulatory RNAs can play, from constituting a network's core to auxiliary roles in adjusting the rate of autoinducer synthesis, mediating cross talk among different parts of a network, or integrating different regulatory inputs to trigger appropriate changes in gene expression. The emphasis is on describing how the study of small RNA-based regulation in quorum sensing and biofilm formation has uncovered new general properties or expanded our understanding of bacterial riboregulation.

AB - Quorum sensing is a vital property of bacteria that enables community-wide coordination of collective behaviors. A key example of such a behavior is biofilm formation, in which groups of bacteria invest in synthesizing a protective, joint extracellular matrix. Quorum sensing involves the production, release, and subsequent detection of extracellular signaling molecules called autoinducers. The architecture of quorum-sensing signal transduction pathways is highly variable among different species of bacteria, but frequently involves posttranscriptional regulation carried out by small regulatory RNA molecules. This review illustrates the diverse roles small trans-acting regulatory RNAs can play, from constituting a network's core to auxiliary roles in adjusting the rate of autoinducer synthesis, mediating cross talk among different parts of a network, or integrating different regulatory inputs to trigger appropriate changes in gene expression. The emphasis is on describing how the study of small RNA-based regulation in quorum sensing and biofilm formation has uncovered new general properties or expanded our understanding of bacterial riboregulation.

U2 - 10.1128/microbiolspec.RWR-0017-2018

DO - 10.1128/microbiolspec.RWR-0017-2018

M3 - Journal article

C2 - 30003870

VL - 6

JO - Microbiology spectrum

JF - Microbiology spectrum

SN - 2165-0497

IS - 4

ER -

ID: 200532041