Christian Holmberg
Associate Professor
Functional Genomics
Ole Maaløes Vej 5
2200 København N.
- 1998
- Published
E2F-1-Induced p53-independent apoptosis in transgenic mice
Holmberg, Christian, Helin, K., Sehested, M. & Karlström, O., 1998, In: Oncogene. 17, 2, p. 143-155 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
A Novel Specific Role for IB Kinase Complex-associated Protein in Cytosolic Stress Signaling
Holmberg, Christian, Katz, S., Lerdrup, M., Herdegen, T., Jaattela, M., Aronheim, A. & Kallunki, T., 2002, In: The Journal of Biological Chemistry. Vol. 277 (35), p. 31918-28Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
JNK2 mediates TNF-induced cell death in mouse embryonic fibroblasts via regulation of both caspase and cathepsin protease pathways
Dietrich, N., Thastrup, J., Holmberg, Christian, Gyrd-Hansen, M., Fehrenbacher, N., Lademann, U., Lerdrup, M., Herdegen, T., Jäättelä, M. & Kallunki, T., 2004, In: Cell Death and Differentiation. 11, 3, p. 301-313 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Conditional E2F1 activation in transgenic mice causes testicular atrophy and dysplasia mimicking human CIS.
Agger, K., Santoni Rugiu, Eric, Holmberg, Christian, Karlström, O. & Helin, K., 2005, In: Oncogene. 24, 5, p. 780-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ddb1 controls genome stability and meiosis in fission yeast
Holmberg, Christian, Fleck, O., Hansen, H. A., Liu, C., Slaaby, R., carr, A. M. & Nielsen, Olaf, 2005, In: Genes & Development. 19, 7, p. 853-862Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Depletion of the AP-1 repressor JDP2 induces cell death similar to apoptosis
Lerdrup, Mads, Holmberg, Christian, Dietrich, N., Shaulian, E., Herdegen, T., Jaattela, Marja & Kallunki, T., 2005, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1745, 1, p. 29-37Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mangel på DNA-byggesten kan give kræft.
Holmberg, Christian & Nielsen, Olaf, 2005, In: Aktuel Naturvidenskab. 3, p. 22-23Research output: Contribution to journal › Journal article › Research
- Published
Transactivation of Schizosaccharomyces pombe cdt2+ stimulates a Pcu4-Ddb1-CSN ubiquitin ligase
Liu, C., Poitelea, M., Watson, A., Yoshida, S., Shimoda, C., Holmberg, Christian, Nielsen, Olaf & Carr, A. M., 2005, In: EMBO Journal. 24, p. 3940-3951Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Genome-wide identification of pheromone-targeted transcrption in fission yeast
Xue-Franzen, Y., Kjærulff, S., Holmberg, Christian, Wright, A. & Nielsen, Olaf, 2006, In: BMC Genomics. 7, p. 303Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Regulation of ribonucleotide reductase by Spd1 involves multiple mechanisms
Nestoras, K., Mohammed, A. H., Schreurs, A., Fleck, O., Watson, A. T., Poitelea, M., O'Shea, Charlotte, Chahwan, C., Holmberg, Christian, Kragelund, Birthe Brandt, Nielsen, Olaf, Osborne, M., Carr, A. M. & Liu, C., 1 Jun 2010, In: Genes & Development. 24, 11, p. 1145-1159 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Break-induced ATR and Ddb1-Cul4(Cdt)² ubiquitin ligase-dependent nucleotide synthesis promotes homologous recombination repair in fission yeast
Moss, J., Tinline-Purvis, H., Walker, C. A., Folkes, L. K., Stratford, M. R., Hayles, J., Hoe, K., Kim, D., Park, H., Kearsey, S. E., Fleck, O., Holmberg, Christian, Nielsen, Olaf & Humphrey, T. C., 1 Dec 2010, In: Genes & Development. 24, 23, p. 2705-16 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Schizosaccharomyces pombe Mms1 channels repair of perturbed replication into Rhp51 independent homologous recombination
Vejrup-Hansen, R., Mizuno, K., Miyabe, I., Fleck, O., Holmberg, Christian, Murray, J. M., Carr, A. M. & Nielsen, Olaf, 2011, In: DNA Repair. 10, 3, p. 283-95 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Cyclin-dependent kinase suppression by WEE1 kinase protects the genome through control of replication initiation and nucleotide consumption
Beck, H., Nähse-Kumpf, V., Larsen, Marie Sofie Yoo, O'Hanlon, K. A., Patzke, S., Holmberg, Christian, Mejlvang, J., Groth, Anja, Nielsen, Olaf, Syljuåsen, R. G. & Sørensen, Claus Storgaard, 2012, In: Molecular and Cellular Biology. 32, 20, p. 4226-4236 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Replication: DNA Building Block Synthesis On Demand
Holmberg, Christian & Nielsen, Olaf, 2012, In: Current Biology. 22, 8, p. R271-R272 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Spd1 accumulation causes genome instability independently of ribonucleotide reductase activity but functions to protect the genome when deoxynucleotide pools are elevated
Fleck, O., Vejrup-Hansen, R., Watson, A., Carr, A. M., Nielsen, Olaf & Holmberg, Christian, 2013, In: Journal of Cell Science. 126, p. 4985-4994 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Spd2 assists Spd1 in the modulation of ribonucleotide reductase architecture but does not regulate deoxynucleotide pools
Vejrup-Hansen, R., Fleck, O., Landvad, K., Fahnøe, Ulrik, Broendum, S. S., Schreurs, A., Kragelund, Birthe Brandt, Carr, A. M., Holmberg, Christian & Nielsen, Olaf, 2014, In: Journal of Cell Science. 127, p. 2460-2470 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Single site suppressors of a fission yeast temperature-sensitive mutant in cdc48 identified by whole genome sequencing
Marinova, I. N., Engelbrecht, J., Ewald, A., Langholm, L. L., Holmberg, Christian, Kragelund, Birthe Brandt, Gordon, C., Nielsen, Olaf & Hartmann-Petersen, Rasmus, 2015, In: P L o S One. 10, 2, 15 p., e0117779.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
UBL/BAG-domain co-chaperones cause cellular stress upon overexpression through constitutive activation of Hsf1
Poulsen, E. G., Kampmeyer, Caroline, Kriegenburg, F., Johansen, Jens Vilstrup, Hofmann, K., Holmberg, Christian & Hartmann-Petersen, Rasmus, Jan 2017, In: Cell Stress & Chaperones. 22, 1, p. 143-154 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deoxynucleoside salvage in fission yeast allows rescue of ribonucleotide reductase deficiency but not Spd1-mediated inhibition of replication
Fleck, O., Fahnøe, Ulrik, Løvschal, K. V., Gasasira, M. U., Marinova, I. N., Kragelund, Birthe Brandt, Carr, A. M., Hartsuiker, E., Holmberg, Christian & Nielsen, Olaf, 25 Apr 2017, In: Genes. 8, 5, 14 p., 128.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Comprehensive profiling of the fission yeast transcription start site activity during stress and media response
Thodberg, Malte, Thieffry, A., Lange, Jette Bornholdt, Boyd, M., Holmberg, Christian, Azad, A., Workman, C. T., Chen, Y., Ekwall, K., Nielsen, Olaf & Sandelin, Albin Gustav, 28 Feb 2019, In: Nucleic Acids Research. 47, 4, p. 1671-1691 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Mutations in a Single Signaling Pathway Allow Cell Growth in Heavy Water
Kampmeyer, Caroline, Johansen, Jens Vilstrup, Holmberg, Christian, Karlson, M., Gersing, S. K., Nunes Bordallo, Heloisa, Kragelund, Birthe Brandt, Lerche, M. H., Jourdain, I., Winther, Jakob R. & Hartmann-Petersen, Rasmus, 2020, In: A C S Synthetic Biology. 9, 4, p. 733-748 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2024
- Published
Checkpoint activation by Spd1: a competition-based system relying on tandem disordered PCNA binding motifs
Olsen, Johan Gotthardt, Prestel, Andreas, Kassem, N., Broendum, S. S., Hossain, Mohammad Shamim, Simonsen, Signe, Grysbæk, M., Mortensen, J., Rytkjær, L. L., Haxholm, G. W., Marabini, R., Holmberg, Christian, Carr, A. M., Crehuet, R., Nielsen, Olaf & Kragelund, Birthe Brandt, 2024, In: Nucleic acids symposium series. 52, 4, p. 2030–2044 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 13485
Most downloads
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1104
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Single site suppressors of a fission yeast temperature-sensitive mutant in cdc48 identified by whole genome sequencing
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
1006
downloads
Genome-wide identification of pheromone-targeted transcrption in fission yeast
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
277
downloads
Deoxynucleoside salvage in fission yeast allows rescue of ribonucleotide reductase deficiency but not Spd1-mediated inhibition of replication
Research output: Contribution to journal › Journal article › Research › peer-review
Published