Christian Holmberg

Christian Holmberg

Associate Professor


  1. 1998
  2. Published

    E2F-1-Induced p53-independent apoptosis in transgenic mice

    Holmberg, Christian, Helin, K., Sehested, M. & Karlström, O., 1998, In: Oncogene. 17, 2, p. 143-155 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2002
  4. Published

    A Novel Specific Role for IB Kinase Complex-associated Protein in Cytosolic Stress Signaling

    Holmberg, Christian, Katz, S., Lerdrup, M., Herdegen, T., Jaattela, M., Aronheim, A. & Kallunki, T., 2002, In: The Journal of Biological Chemistry. Vol. 277 (35), p. 31918-28

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2004
  6. JNK2 mediates TNF-induced cell death in mouse embryonic fibroblasts via regulation of both caspase and cathepsin protease pathways

    Dietrich, N., Thastrup, J., Holmberg, Christian, Gyrd-Hansen, M., Fehrenbacher, N., Lademann, U., Lerdrup, M., Herdegen, T., Jäättelä, M. & Kallunki, T., 2004, In: Cell Death and Differentiation. 11, 3, p. 301-313 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2005
  8. Published

    Conditional E2F1 activation in transgenic mice causes testicular atrophy and dysplasia mimicking human CIS.

    Agger, K., Santoni Rugiu, Eric, Holmberg, Christian, Karlström, O. & Helin, K., 2005, In: Oncogene. 24, 5, p. 780-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Ddb1 controls genome stability and meiosis in fission yeast

    Holmberg, Christian, Fleck, O., Hansen, H. A., Liu, C., Slaaby, R., carr, A. M. & Nielsen, Olaf, 2005, In: Genes & Development. 19, 7, p. 853-862

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Depletion of the AP-1 repressor JDP2 induces cell death similar to apoptosis

    Lerdrup, Mads, Holmberg, Christian, Dietrich, N., Shaulian, E., Herdegen, T., Jaattela, Marja & Kallunki, T., 2005, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1745, 1, p. 29-37

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Mangel på DNA-byggesten kan give kræft.

    Holmberg, Christian & Nielsen, Olaf, 2005, In: Aktuel Naturvidenskab. 3, p. 22-23

    Research output: Contribution to journalJournal articleResearch

  12. Published

    Transactivation of Schizosaccharomyces pombe cdt2+ stimulates a Pcu4-Ddb1-CSN ubiquitin ligase

    Liu, C., Poitelea, M., Watson, A., Yoshida, S., Shimoda, C., Holmberg, Christian, Nielsen, Olaf & Carr, A. M., 2005, In: EMBO Journal. 24, p. 3940-3951

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2006
  14. Published

    Genome-wide identification of pheromone-targeted transcrption in fission yeast

    Xue-Franzen, Y., Kjærulff, S., Holmberg, Christian, Wright, A. & Nielsen, Olaf, 2006, In: BMC Genomics. 7, p. 303

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2010
  16. Published

    Regulation of ribonucleotide reductase by Spd1 involves multiple mechanisms

    Nestoras, K., Mohammed, A. H., Schreurs, A., Fleck, O., Watson, A. T., Poitelea, M., O'Shea, Charlotte, Chahwan, C., Holmberg, Christian, Kragelund, Birthe Brandt, Nielsen, Olaf, Osborne, M., Carr, A. M. & Liu, C., 1 Jun 2010, In: Genes & Development. 24, 11, p. 1145-1159 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Break-induced ATR and Ddb1-Cul4(Cdt)² ubiquitin ligase-dependent nucleotide synthesis promotes homologous recombination repair in fission yeast

    Moss, J., Tinline-Purvis, H., Walker, C. A., Folkes, L. K., Stratford, M. R., Hayles, J., Hoe, K., Kim, D., Park, H., Kearsey, S. E., Fleck, O., Holmberg, Christian, Nielsen, Olaf & Humphrey, T. C., 1 Dec 2010, In: Genes & Development. 24, 23, p. 2705-16 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 2011
  19. Published

    Schizosaccharomyces pombe Mms1 channels repair of perturbed replication into Rhp51 independent homologous recombination

    Vejrup-Hansen, R., Mizuno, K., Miyabe, I., Fleck, O., Holmberg, Christian, Murray, J. M., Carr, A. M. & Nielsen, Olaf, 2011, In: DNA Repair. 10, 3, p. 283-95 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2012
  21. Published

    Cyclin-dependent kinase suppression by WEE1 kinase protects the genome through control of replication initiation and nucleotide consumption

    Beck, H., Nähse-Kumpf, V., Larsen, Marie Sofie Yoo, O'Hanlon, K. A., Patzke, S., Holmberg, Christian, Mejlvang, J., Groth, Anja, Nielsen, Olaf, Syljuåsen, R. G. & Sørensen, Claus Storgaard, 2012, In: Molecular and Cellular Biology. 32, 20, p. 4226-4236 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Replication: DNA Building Block Synthesis On Demand

    Holmberg, Christian & Nielsen, Olaf, 2012, In: Current Biology. 22, 8, p. R271-R272 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. 2013
  24. Published

    Spd1 accumulation causes genome instability independently of ribonucleotide reductase activity but functions to protect the genome when deoxynucleotide pools are elevated

    Fleck, O., Vejrup-Hansen, R., Watson, A., Carr, A. M., Nielsen, Olaf & Holmberg, Christian, 2013, In: Journal of Cell Science. 126, p. 4985-4994 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2014
  26. Published

    Spd2 assists Spd1 in the modulation of ribonucleotide reductase architecture but does not regulate deoxynucleotide pools

    Vejrup-Hansen, R., Fleck, O., Landvad, K., Fahnøe, Ulrik, Broendum, S. S., Schreurs, A., Kragelund, Birthe Brandt, Carr, A. M., Holmberg, Christian & Nielsen, Olaf, 2014, In: Journal of Cell Science. 127, p. 2460-2470 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2015
  28. Published

    Single site suppressors of a fission yeast temperature-sensitive mutant in cdc48 identified by whole genome sequencing

    Marinova, I. N., Engelbrecht, J., Ewald, A., Langholm, L. L., Holmberg, Christian, Kragelund, Birthe Brandt, Gordon, C., Nielsen, Olaf & Hartmann-Petersen, Rasmus, 2015, In: P L o S One. 10, 2, 15 p., e0117779.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 2017
  30. Published

    UBL/BAG-domain co-chaperones cause cellular stress upon overexpression through constitutive activation of Hsf1

    Poulsen, E. G., Kampmeyer, Caroline, Kriegenburg, F., Johansen, Jens Vilstrup, Hofmann, K., Holmberg, Christian & Hartmann-Petersen, Rasmus, Jan 2017, In: Cell Stress & Chaperones. 22, 1, p. 143-154 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Deoxynucleoside salvage in fission yeast allows rescue of ribonucleotide reductase deficiency but not Spd1-mediated inhibition of replication

    Fleck, O., Fahnøe, Ulrik, Løvschal, K. V., Gasasira, M. U., Marinova, I. N., Kragelund, Birthe Brandt, Carr, A. M., Hartsuiker, E., Holmberg, Christian & Nielsen, Olaf, 25 Apr 2017, In: Genes. 8, 5, 14 p., 128.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2019
  33. Published

    Comprehensive profiling of the fission yeast transcription start site activity during stress and media response

    Thodberg, Malte, Thieffry, A., Lange, Jette Bornholdt, Boyd, M., Holmberg, Christian, Azad, A., Workman, C. T., Chen, Y., Ekwall, K., Nielsen, Olaf & Sandelin, Albin Gustav, 28 Feb 2019, In: Nucleic Acids Research. 47, 4, p. 1671-1691 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. 2020
  35. Published

    Mutations in a Single Signaling Pathway Allow Cell Growth in Heavy Water

    Kampmeyer, Caroline, Johansen, Jens Vilstrup, Holmberg, Christian, Karlson, M., Gersing, S. K., Nunes Bordallo, Heloisa, Kragelund, Birthe Brandt, Lerche, M. H., Jourdain, I., Winther, Jakob R. & Hartmann-Petersen, Rasmus, 2020, In: A C S Synthetic Biology. 9, 4, p. 733-748 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. 2024
  37. Published

    Checkpoint activation by Spd1: a competition-based system relying on tandem disordered PCNA binding motifs

    Olsen, Johan Gotthardt, Prestel, Andreas, Kassem, N., Broendum, S. S., Hossain, Mohammad Shamim, Simonsen, Signe, Grysbæk, M., Mortensen, J., Rytkjær, L. L., Haxholm, G. W., Marabini, R., Holmberg, Christian, Carr, A. M., Crehuet, R., Nielsen, Olaf & Kragelund, Birthe Brandt, 2024, In: Nucleic acids symposium series. 52, 4, p. 2030–2044 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 13485