Kaare Teilum
Professor
Biomolecular Sciences
Ole Maaløes Vej 5
2200 København N.
- 2024
- Published
A druggable conformational switch in the c-MYC transactivation domain
Lama, D., Vosselman, T., Sahin, Cagla, Liaño-pons, J., Cerrato, C. P., Nilsson, L., Teilum, Kaare, Lane, D. P., Landreh, M. & Arsenian Henriksson, M., 2024, In: Nature Communications. 15, 1, 14 p., 1865.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular switching in transcription through splicing and proline-isomerization regulates stress responses in plants
Theisen, Frederik Friis, Prestel, Andreas, Elkjær, Steffie Martina H, Leurs, Y. H. A., Morffy, N., Strader, L. C., O'Shea, Charlotte, Teilum, Kaare, Kragelund, Birthe Brandt & Skriver, Karen, 2024, In: Nature Communications. 15, 1, 13 p., 592.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Comment on “Intrinsic protein disorder uncouples affinity from binding specificity”
Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2023, In: Protein Science. 32, 4, 2 p., e4602.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Mass Spectrometry of RNA-Binding Proteins during Liquid-Liquid Phase Separation Reveals Distinct Assembly Mechanisms and Droplet Architectures
Sahin, Cagla, Motso, A., Gu, X., Feyrer, H., Lama, D., Arndt, T., Rising, A., Gese, G. V., Haellberg, B. M., Marklund, E. G., Schafer, N. P., Petzold, K., Teilum, Kaare, Wolynes, P. G. & Landreh, M., 2023, In: Journal of the American Chemical Society. 145, 19, 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Slow conformational changes in the rigid and highly stable chymotrypsin inhibitor 2
Gavrilov, Y., Prestel, Andreas, Lindorff-Larsen, Kresten & Teilum, Kaare, 2023, In: Protein Science. 32, 4, 9 p., 4604.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Bidirectional protein–protein interactions control liquid–liquid phase separation of PSD-95 and its interaction partners
Christensen, N. R., Pedersen, Christian Parsbæk, Sereikaité, Vita, Pedersen, J. N., Vistrup-Parry, M., Sørensen, Andreas Toft, Otzen, D., Teilum, Kaare, Madsen, Kenneth Lindegaard & Strømgaard, Kristian, 2022, In: iScience. 25, 2, 26 p., 103808.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disease-linked mutations cause exposure of a protein quality control degron
Kampmeyer, Caroline, Larsen-Ledet, Sven, Wagnkilde, M. R., Michelsen, M., Iversen, Henriette Kring Mangor, Nielsen, S. V., Lindemose, Søren, Caregnato, A., Ravid, T., Stein, Amelie, Teilum, Kaare, Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2022, In: Structure. 30, 9, p. 1245-1253.e5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Double Mutant of Chymotrypsin Inhibitor 2 Stabilized through Increased Conformational Entropy
Gavrilov, Y., Kümmerer, Felix, Orioli, S., Prestel, Andreas, Lindorff-Larsen, Kresten & Teilum, Kaare, 2022, In: Biochemistry. 61, 3, p. 160-170 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
A dual-reporter system for investigating and optimizing protein translation and folding in E. coli
Zutz, A., Hamborg, L., Pedersen, L. E., Kassem, M. M., Papaleo, E., Koza, A., Herrgård, M. J., Ingemann Jensen, S., Teilum, Kaare, Lindorff-Larsen, Kresten & Nielsen, A. T., 2021, In: Nature Communications. 12, 15 p., 6093.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Binding Revisited - Avidity in Cellular Function and Signaling
qrc243, qrc243 & Teilum, Kaare, 2021, In: Frontiers in Molecular Biosciences. 7, 13 p., 615565.Research output: Contribution to journal › Review › Research › peer-review
- Published
Charge Engineering Reveals the Roles of Ionizable Side Chains in Electrospray Ionization Mass Spectrometry
Abramsson, M. L., Sahin, C., Hopper, J. T. S., Branca, R. M. M., Danielsson, J., Xu, M., Chandler, S. A., Österlund, N., Ilag, L. L., Leppert, A., Costeira-Paulo, J., Lang, L., Teilum, K., Laganowsky, A., Benesch, J. L. P., Oliveberg, M., Robinson, C. V., Marklund, E. G., Allison, T. M., Winther, J. R. & 1 others, , 2021, In: JACS Au. 1, 12, p. 2385-2393 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Charge Interactions in a Highly Charge-Depleted Protein
Hervø-Hansen, S., Højgaard, C., Johansson, Kristoffer Enøe, Wang, Y., Wahni, K., Young, D., Messens, J., Teilum, Kaare, Lindorff-Larsen, Kresten & Winther, Jakob R., 2021, In: Journal of the American Chemical Society. 143, 6, p. 2500-2508 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fitting Side-Chain NMR Relaxation Data Using Molecular Simulations
Kümmerer, Felix, Orioli, S., Harding-Larsen, D., Hoffmann, F., Gavrilov, Y., Teilum, Kaare & Lindorff-Larsen, Kresten, 2021, In: Journal of Chemical Theory and Computation. 17, 8, p. 5262-5275 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Linking thermodynamics and measurements of protein stability
Lindorff-Larsen, Kresten & Teilum, Kaare, 2021, In: Protein engineering, design & selection : PEDS. 34, 13 p., gzab002.Research output: Contribution to journal › Review › Research › peer-review
- Published
On the specificity of protein-protein interactions in the context of disorder
Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2021, In: Biochemical Journal. 478, 11, p. 2035-2050 16 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Software for reconstruction of nonuniformly sampled NMR data
Pedersen, Christian Parsbæk, Prestel, Andreas & Teilum, Kaare, 2021, In: Magnetic Resonance in Chemistry. 59, 3, p. 315-323 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Synergistic stabilization of a double mutant in chymotrypsin inhibitor 2 from a library screen in E. coli
Hamborg, L., Granata, D., Olsen, Johan Gotthardt, Roche, J. V., Pedersen, L. E., Nielsen, A. T., Lindorff-Larsen, Kresten & Teilum, Kaare, 2021, In: Communications Biology . 4, 9 p., 980.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ubiquitin Interacting Motifs: Duality Between Structured and Disordered Motifs
Lambrughi, M., Maiani, E., Fas, B. A., Shaw, G. S., Kragelund, Birthe Brandt, Lindorff-Larsen, Kresten, Teilum, Kaare, Invernizzi, G. & Papaleo, E., 2021, In: Frontiers in Molecular Biosciences. 8, 14 p., 676235.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain
Christensen, N. R., De Luca, M., Lever, M. B., Richner, M., Hansen, A. B., Noes-Holt, G., Jensen, K. L., Rathje, M., Jensen, D. B., Erlendsson, S., Bartling, C. R. O., Ammendrup-Johnsen, I., Pedersen, S. E., Schönauer, M., Nissen, K. B., Midtgaard, S. R., Teilum, K., Arleth, L., Sørensen, A. T., Bach, A. & 5 others, , 2020, In: EMBO Molecular Medicine. 12, 6, 25 p., e11248.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Conformational heterogeneity of Savinase from NMR, HDX-MS and X-ray diffraction analysis
Wu, S., Nguyen, T. T. T. N., Moroz, O. V., Turkenburg, J. P., Nielsen, J. E., Wilson, K. S., Rand, Kasper Dyrberg & Teilum, Kaare, 2020, In: PeerJ. 8, 17 p., e9408.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Global analysis of protein stability by temperature and chemical denaturation
Hamborg, L., Horsted, E. W., Johansson, Kristoffer Enøe, Willemoës, Martin, Lindorff-Larsen, Kresten & Teilum, Kaare, 2020, In: Analytical Biochemistry. 605, 7 p., 113863.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Corrigendum: Relax: The analysis of biomolecular kinetics and thermodynamics using NMR relaxation dispersion data (Bioinformatics (2014) DOI: 10.1093/bioinformatics/btu166)
Morin, S., Linnet, T. E., Lescanne, M., Schanda, P., Thompson, G. S., Tollinger, M., Teilum, Kaare, Gagné, S., Marion, D., Griesinger, C., Blackledge, M. & D'Auvergne, E. J., 15 Oct 2019, In: Bioinformatics. 35, 20, p. 4205 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Mechanisms of PDZ domain scaffold assembly illuminated by use of supported cell membrane sheets
qrc243, qrc243, Thorsen, T. S., Vauquelin, G., Ammendrup-Johnsen, I., Wirth, V., Martinez, Karen Laurence, Teilum, Kaare, Gether, Ulrik & Madsen, Kenneth Lindegaard, 2019, In: eLife. 8, p. 1-27 e39180.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Capsid Domain of Arc Changes Its Oligomerization Propensity through Direct Interaction with the NMDA Receptor
Nielsen, L. D., Pedersen, Christian Parsbæk, qrc243, qrc243 & Teilum, Kaare, 2019, In: Structure. 27, 7, p. 1071-1081, e1-e5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The three-dimensional structure of an H-superfamily conotoxin reveals a granulin fold arising from a common ICK cysteine framework
Nielsen, L. D., Foged, M. M., Albert, A., Bertelsen, A. B., Søltoft, C. L., Robinson, S. D., Petersen, S. V., Purcell, A. W., Olivera, B. M., Norton, R. S., Vasskog, T., Safavi, Helena, Teilum, Kaare & Ellgaard, Lars, 2019, In: The Journal of Biological Chemistry. 294, 22, p. 8745-8759Research output: Contribution to journal › Journal article › Research › peer-review
ID: 985685
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relax: the analysis of biomolecular kinetics and thermodynamics using NMR relaxation dispersion data
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
773
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Off-resonance rotating-frame relaxation dispersion experiment for 13C in aromatic side chains using L-optimized TROSY-selection
Research output: Contribution to journal › Journal article › Research › peer-review
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347
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(S)Pinning down protein interactions by NMR
Research output: Contribution to journal › Review › Research › peer-review
Published