Kaare Teilum

Kaare Teilum

Professor


  1. 2024
  2. Published

    A druggable conformational switch in the c-MYC transactivation domain

    Lama, D., Vosselman, T., Sahin, Cagla, Liaño-pons, J., Cerrato, C. P., Nilsson, L., Teilum, Kaare, Lane, D. P., Landreh, M. & Arsenian Henriksson, M., 2024, In: Nature Communications. 15, 1, 14 p., 1865.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Molecular switching in transcription through splicing and proline-isomerization regulates stress responses in plants

    Theisen, Frederik Friis, Prestel, Andreas, Elkjær, Steffie Martina H, Leurs, Y. H. A., Morffy, N., Strader, L. C., O'Shea, Charlotte, Teilum, Kaare, Kragelund, Birthe Brandt & Skriver, Karen, 2024, In: Nature Communications. 15, 1, 13 p., 592.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2023
  5. Published

    Comment on “Intrinsic protein disorder uncouples affinity from binding specificity

    Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2023, In: Protein Science. 32, 4, 2 p., e4602.

    Research output: Contribution to journalComment/debateResearchpeer-review

  6. Published

    Mass Spectrometry of RNA-Binding Proteins during Liquid-Liquid Phase Separation Reveals Distinct Assembly Mechanisms and Droplet Architectures

    Sahin, Cagla, Motso, A., Gu, X., Feyrer, H., Lama, D., Arndt, T., Rising, A., Gese, G. V., Haellberg, B. M., Marklund, E. G., Schafer, N. P., Petzold, K., Teilum, Kaare, Wolynes, P. G. & Landreh, M., 2023, In: Journal of the American Chemical Society. 145, 19, 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Slow conformational changes in the rigid and highly stable chymotrypsin inhibitor 2

    Gavrilov, Y., Prestel, Andreas, Lindorff-Larsen, Kresten & Teilum, Kaare, 2023, In: Protein Science. 32, 4, 9 p., 4604.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2022
  9. Published

    Bidirectional protein–protein interactions control liquid–liquid phase separation of PSD-95 and its interaction partners

    Christensen, N. R., Pedersen, Christian Parsbæk, Sereikaité, Vita, Pedersen, J. N., Vistrup-Parry, M., Sørensen, Andreas Toft, Otzen, D., Teilum, Kaare, Madsen, Kenneth Lindegaard & Strømgaard, Kristian, 2022, In: iScience. 25, 2, 26 p., 103808.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Disease-linked mutations cause exposure of a protein quality control degron

    Kampmeyer, Caroline, Larsen-Ledet, Sven, Wagnkilde, M. R., Michelsen, M., Iversen, Henriette Kring Mangor, Nielsen, S. V., Lindemose, Søren, Caregnato, A., Ravid, T., Stein, Amelie, Teilum, Kaare, Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2022, In: Structure. 30, 9, p. 1245-1253.e5

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Double Mutant of Chymotrypsin Inhibitor 2 Stabilized through Increased Conformational Entropy

    Gavrilov, Y., Kümmerer, Felix, Orioli, S., Prestel, Andreas, Lindorff-Larsen, Kresten & Teilum, Kaare, 2022, In: Biochemistry. 61, 3, p. 160-170 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2021
  13. Published

    A dual-reporter system for investigating and optimizing protein translation and folding in E. coli

    Zutz, A., Hamborg, L., Pedersen, L. E., Kassem, M. M., Papaleo, E., Koza, A., Herrgård, M. J., Ingemann Jensen, S., Teilum, Kaare, Lindorff-Larsen, Kresten & Nielsen, A. T., 2021, In: Nature Communications. 12, 15 p., 6093.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Binding Revisited - Avidity in Cellular Function and Signaling

    qrc243, qrc243 & Teilum, Kaare, 2021, In: Frontiers in Molecular Biosciences. 7, 13 p., 615565.

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    Charge Engineering Reveals the Roles of Ionizable Side Chains in Electrospray Ionization Mass Spectrometry

    Abramsson, M. L., Sahin, C., Hopper, J. T. S., Branca, R. M. M., Danielsson, J., Xu, M., Chandler, S. A., Österlund, N., Ilag, L. L., Leppert, A., Costeira-Paulo, J., Lang, L., Teilum, K., Laganowsky, A., Benesch, J. L. P., Oliveberg, M., Robinson, C. V., Marklund, E. G., Allison, T. M., Winther, J. R. & 1 others, Landreh, M., 2021, In: JACS Au. 1, 12, p. 2385-2393 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Charge Interactions in a Highly Charge-Depleted Protein

    Hervø-Hansen, S., Højgaard, C., Johansson, Kristoffer Enøe, Wang, Y., Wahni, K., Young, D., Messens, J., Teilum, Kaare, Lindorff-Larsen, Kresten & Winther, Jakob R., 2021, In: Journal of the American Chemical Society. 143, 6, p. 2500-2508 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Fitting Side-Chain NMR Relaxation Data Using Molecular Simulations

    Kümmerer, Felix, Orioli, S., Harding-Larsen, D., Hoffmann, F., Gavrilov, Y., Teilum, Kaare & Lindorff-Larsen, Kresten, 2021, In: Journal of Chemical Theory and Computation. 17, 8, p. 5262-5275 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Linking thermodynamics and measurements of protein stability

    Lindorff-Larsen, Kresten & Teilum, Kaare, 2021, In: Protein engineering, design & selection : PEDS. 34, 13 p., gzab002.

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published

    On the specificity of protein-protein interactions in the context of disorder

    Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2021, In: Biochemical Journal. 478, 11, p. 2035-2050 16 p.

    Research output: Contribution to journalReviewResearchpeer-review

  20. Published

    Software for reconstruction of nonuniformly sampled NMR data

    Pedersen, Christian Parsbæk, Prestel, Andreas & Teilum, Kaare, 2021, In: Magnetic Resonance in Chemistry. 59, 3, p. 315-323 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    Synergistic stabilization of a double mutant in chymotrypsin inhibitor 2 from a library screen in E. coli

    Hamborg, L., Granata, D., Olsen, Johan Gotthardt, Roche, J. V., Pedersen, L. E., Nielsen, A. T., Lindorff-Larsen, Kresten & Teilum, Kaare, 2021, In: Communications Biology . 4, 9 p., 980.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Ubiquitin Interacting Motifs: Duality Between Structured and Disordered Motifs

    Lambrughi, M., Maiani, E., Fas, B. A., Shaw, G. S., Kragelund, Birthe Brandt, Lindorff-Larsen, Kresten, Teilum, Kaare, Invernizzi, G. & Papaleo, E., 2021, In: Frontiers in Molecular Biosciences. 8, 14 p., 676235.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. 2020
  24. Published

    A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain

    Christensen, N. R., De Luca, M., Lever, M. B., Richner, M., Hansen, A. B., Noes-Holt, G., Jensen, K. L., Rathje, M., Jensen, D. B., Erlendsson, S., Bartling, C. R. O., Ammendrup-Johnsen, I., Pedersen, S. E., Schönauer, M., Nissen, K. B., Midtgaard, S. R., Teilum, K., Arleth, L., Sørensen, A. T., Bach, A. & 5 others, Strømgaard, Kristian, Meehan, Claire Francesca, Vægter, C. B., Gether, Ulrik & Madsen, Kenneth Lindegaard, 2020, In: EMBO Molecular Medicine. 12, 6, 25 p., e11248.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Conformational heterogeneity of Savinase from NMR, HDX-MS and X-ray diffraction analysis

    Wu, S., Nguyen, T. T. T. N., Moroz, O. V., Turkenburg, J. P., Nielsen, J. E., Wilson, K. S., Rand, Kasper Dyrberg & Teilum, Kaare, 2020, In: PeerJ. 8, 17 p., e9408.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Global analysis of protein stability by temperature and chemical denaturation

    Hamborg, L., Horsted, E. W., Johansson, Kristoffer Enøe, Willemoës, Martin, Lindorff-Larsen, Kresten & Teilum, Kaare, 2020, In: Analytical Biochemistry. 605, 7 p., 113863.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2019
  28. Published

    Corrigendum: Relax: The analysis of biomolecular kinetics and thermodynamics using NMR relaxation dispersion data (Bioinformatics (2014) DOI: 10.1093/bioinformatics/btu166)

    Morin, S., Linnet, T. E., Lescanne, M., Schanda, P., Thompson, G. S., Tollinger, M., Teilum, Kaare, Gagné, S., Marion, D., Griesinger, C., Blackledge, M. & D'Auvergne, E. J., 15 Oct 2019, In: Bioinformatics. 35, 20, p. 4205 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  29. Published

    Mechanisms of PDZ domain scaffold assembly illuminated by use of supported cell membrane sheets

    qrc243, qrc243, Thorsen, T. S., Vauquelin, G., Ammendrup-Johnsen, I., Wirth, V., Martinez, Karen Laurence, Teilum, Kaare, Gether, Ulrik & Madsen, Kenneth Lindegaard, 2019, In: eLife. 8, p. 1-27 e39180.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    The Capsid Domain of Arc Changes Its Oligomerization Propensity through Direct Interaction with the NMDA Receptor

    Nielsen, L. D., Pedersen, Christian Parsbæk, qrc243, qrc243 & Teilum, Kaare, 2019, In: Structure. 27, 7, p. 1071-1081, e1-e5

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    The three-dimensional structure of an H-superfamily conotoxin reveals a granulin fold arising from a common ICK cysteine framework

    Nielsen, L. D., Foged, M. M., Albert, A., Bertelsen, A. B., Søltoft, C. L., Robinson, S. D., Petersen, S. V., Purcell, A. W., Olivera, B. M., Norton, R. S., Vasskog, T., Safavi, Helena, Teilum, Kaare & Ellgaard, Lars, 2019, In: The Journal of Biological Chemistry. 294, 22, p. 8745-8759

    Research output: Contribution to journalJournal articleResearchpeer-review

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