Olaf Nielsen
Professor
Functional Genomics
Ole Maaløes Vej 5
2200 København N.
- 2024
- Published
Checkpoint activation by Spd1: a competition-based system relying on tandem disordered PCNA binding motifs
Olsen, Johan Gotthardt, Prestel, Andreas, Kassem, N., Broendum, S. S., Hossain, Mohammad Shamim, Simonsen, Signe, Grysbæk, M., Mortensen, J., Rytkjær, L. L., Haxholm, G. W., Marabini, R., Holmberg, Christian, Carr, A. M., Crehuet, R., Nielsen, Olaf & Kragelund, Birthe Brandt, 2024, In: Nucleic acids symposium series. 52, 4, p. 2030–2044 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Revised fission yeast gene and allele nomenclature guidelines for machine readability
Lera-ramírez, M., Bähler, J., Mata, J., Rutherford, K., Hoffman, C. S., Lambert, S., Oliferenko, S., Martin, S. G., Gould, K. L., Du, L., Sabatinos, S. A., Forsburg, S. L., Nielsen, Olaf, Nurse, P. & Wood, V., 2023, In: Genetics. 225, 3, 10 p., iyad143.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Temporal phosphoproteomics reveals WEE1-dependent control of 53BP1 pathway
Petrosius, V., Benada, Jan, Nielsen, Olaf, Schoof, E. M. & Sørensen, Claus Storgaard, 2023, In: iScience. 26, 1, 24 p., 105806.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
A context-dependent and disordered ubiquitin-binding motif
Dreier, Jesper Elmsted, Prestel, Andreas, Martins, J. M., Brøndum, S. S., Nielsen, Olaf, Garbers, Anna Engstrøm, Suga, H., Boomsma, Wouter, Rogers, Joseph Matthew, Hartmann-Petersen, Rasmus & Kragelund, Birthe Brandt, 2022, In: Cellular and molecular life sciences : CMLS. 79, 9, 21 p., 484.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Comprehensive profiling of the fission yeast transcription start site activity during stress and media response
Thodberg, Malte, Thieffry, A., Lange, Jette Bornholdt, Boyd, M., Holmberg, Christian, Azad, A., Workman, C. T., Chen, Y., Ekwall, K., Nielsen, Olaf & Sandelin, Albin Gustav, 28 Feb 2019, In: Nucleic Acids Research. 47, 4, p. 1671-1691 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The PCNA interaction motifs revisited: thinking outside the PIP-box
Prestel, Andreas, Wichmann, N., Martins, J. M., Marabini, R., Kassem, N., Broendum, S. S., Otterlei, M., Nielsen, Olaf, Willemoës, Martin, Ploug, Michael, Boomsma, Wouter & Kragelund, Birthe Brandt, 2019, In: Cellular and Molecular Life Sciences. 76, 24, p. 4923-4943Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Functional and Expression Analyses of the Pneumocystis MAT Genes Suggest Obligate Sexuality through Primary Homothallism within Host Lungs
Richard, S., Almeida, J. M. G. C. F., Cissé, O. H., Luraschi, A., Nielsen, Olaf, Pagni, M. & Hauser, P. M., 2018, In: mBio. 9, 1, 10 p., e02201-17.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Analysis of RNA metabolism in fission yeast
Wise, J. A. & Nielsen, Olaf, May 2017, In: Cold Spring Harbor Protocols. 2017, 5, p. 365-372 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deoxynucleoside salvage in fission yeast allows rescue of ribonucleotide reductase deficiency but not Spd1-mediated inhibition of replication
Fleck, O., Fahnøe, Ulrik, Løvschal, K. V., Gasasira, M. U., Marinova, I. N., Kragelund, Birthe Brandt, Carr, A. M., Hartsuiker, E., Holmberg, Christian & Nielsen, Olaf, 25 Apr 2017, In: Genes. 8, 5, 14 p., 128.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Regulating retrotransposon activity through the use of alternative transcription start sites
Persson, J., Steglich, B., Smialowska, A., Boyd, M., Lange, Jette Bornholdt, Andersson, Robin, Schurra, C., Arcangioli, B., Sandelin, Albin Gustav, Nielsen, Olaf & Ekwall, K., 2016, In: E M B O Reports. 17, 5, p. 753-768 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synchronization of S phase in Schizosaccharomyces pombe cells by transient exposure to M-factor pheromone
Nielsen, Olaf, 2016, In: Cold Spring Harbor Protocols. 2016, 9, p. 768-772 5 p.Research output: Contribution to journal › Journal article › Research
- 2015
- Published
An IPTG-inducible derivative of the fission yeast nmt promoter
Kjærulff, S. & Nielsen, Olaf, 2015, In: Yeast. 32, p. 469-478 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single site suppressors of a fission yeast temperature-sensitive mutant in cdc48 identified by whole genome sequencing
Marinova, I. N., Engelbrecht, J., Ewald, A., Langholm, L. L., Holmberg, Christian, Kragelund, Birthe Brandt, Gordon, C., Nielsen, Olaf & Hartmann-Petersen, Rasmus, 2015, In: P L o S One. 10, 2, 15 p., e0117779.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
C/EBPα is dispensable for the ontogeny of PD-1+ CD4+ memory T cells but restricts their expansion in an age-dependent manner
Norrie, I. C., Ohlsson, E., Nielsen, Olaf, Hasemann, M. S. & Porse, Bo Torben, 2014, In: P L o S One. 9, 1, p. 1-9 9 p., e84728.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spd2 assists Spd1 in the modulation of ribonucleotide reductase architecture but does not regulate deoxynucleotide pools
Vejrup-Hansen, R., Fleck, O., Landvad, K., Fahnøe, Ulrik, Broendum, S. S., Schreurs, A., Kragelund, Birthe Brandt, Carr, A. M., Holmberg, Christian & Nielsen, Olaf, 2014, In: Journal of Cell Science. 127, p. 2460-2470 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Spd1 accumulation causes genome instability independently of ribonucleotide reductase activity but functions to protect the genome when deoxynucleotide pools are elevated
Fleck, O., Vejrup-Hansen, R., Watson, A., Carr, A. M., Nielsen, Olaf & Holmberg, Christian, 2013, In: Journal of Cell Science. 126, p. 4985-4994 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Cyclin-dependent kinase suppression by WEE1 kinase protects the genome through control of replication initiation and nucleotide consumption
Beck, H., Nähse-Kumpf, V., Larsen, Marie Sofie Yoo, O'Hanlon, K. A., Patzke, S., Holmberg, Christian, Mejlvang, J., Groth, Anja, Nielsen, Olaf, Syljuåsen, R. G. & Sørensen, Claus Storgaard, 2012, In: Molecular and Cellular Biology. 32, 20, p. 4226-4236 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Replication: DNA Building Block Synthesis On Demand
Holmberg, Christian & Nielsen, Olaf, 2012, In: Current Biology. 22, 8, p. R271-R272 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Schizosaccharomyces pombe Mms1 channels repair of perturbed replication into Rhp51 independent homologous recombination
Vejrup-Hansen, R., Mizuno, K., Miyabe, I., Fleck, O., Holmberg, Christian, Murray, J. M., Carr, A. M. & Nielsen, Olaf, 2011, In: DNA Repair. 10, 3, p. 283-95 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Break-induced ATR and Ddb1-Cul4(Cdt)² ubiquitin ligase-dependent nucleotide synthesis promotes homologous recombination repair in fission yeast
Moss, J., Tinline-Purvis, H., Walker, C. A., Folkes, L. K., Stratford, M. R., Hayles, J., Hoe, K., Kim, D., Park, H., Kearsey, S. E., Fleck, O., Holmberg, Christian, Nielsen, Olaf & Humphrey, T. C., 1 Dec 2010, In: Genes & Development. 24, 23, p. 2705-16 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of ribonucleotide reductase by Spd1 involves multiple mechanisms
Nestoras, K., Mohammed, A. H., Schreurs, A., Fleck, O., Watson, A. T., Poitelea, M., O'Shea, Charlotte, Chahwan, C., Holmberg, Christian, Kragelund, Birthe Brandt, Nielsen, Olaf, Osborne, M., Carr, A. M. & Liu, C., 1 Jun 2010, In: Genes & Development. 24, 11, p. 1145-1159 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Once in a lifetime: strategies for preventing re-replication in prokaryotic and eukaryotic cells.
Nielsen, Olaf & Løbner-Olesen, Anders, 2008, In: EMBO Reports. 9, 2, p. 151-156 5 p.Research output: Contribution to journal › Review › Research › peer-review
- 2007
- Published
Cdk phosphorylation of the Ste11 transcription factor constrains differentiation-specific transcription to G1.
Kjaerulff, S., Andersen, N. R., Borup, M. T. & Nielsen, Olaf, 2007, In: Genes & Development. 21, 3, p. 347-59 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fission yeast goes synthetic.
Nielsen, Olaf, 2007, In: Nature Methods. 4, 10, p. 777-8 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Genome-wide identification of pheromone-targeted transcrption in fission yeast
Xue-Franzen, Y., Kjærulff, S., Holmberg, Christian, Wright, A. & Nielsen, Olaf, 2006, In: BMC Genomics. 7, p. 303Research output: Contribution to journal › Journal article › Research › peer-review
ID: 3496
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2349
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Once in a lifetime: strategies for preventing re-replication in prokaryotic and eukaryotic cells.
Research output: Contribution to journal › Review › Research › peer-review
Published -
1832
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Mik1 levels accumulate in S phase and may mediate an intrinsic link between S phase and mitosis
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
1549
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C/EBPα is dispensable for the ontogeny of PD-1+ CD4+ memory T cells but restricts their expansion in an age-dependent manner
Research output: Contribution to journal › Journal article › Research › peer-review
Published