A proximal promoter element required for positive transcriptional control by guanosine tetraphosphate and DKSA protein during the stringent response

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

A proximal promoter element required for positive transcriptional control by guanosine tetraphosphate and DKSA protein during the stringent response. / Gummesson, Bertil; Lovmar, Martin; Nyström, Thomas.

In: Journal of Biological Chemistry, Vol. 288, No. 29, 19.07.2013, p. 21055-21064.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Gummesson, B, Lovmar, M & Nyström, T 2013, 'A proximal promoter element required for positive transcriptional control by guanosine tetraphosphate and DKSA protein during the stringent response', Journal of Biological Chemistry, vol. 288, no. 29, pp. 21055-21064. https://doi.org/10.1074/jbc.M113.479998

APA

Gummesson, B., Lovmar, M., & Nyström, T. (2013). A proximal promoter element required for positive transcriptional control by guanosine tetraphosphate and DKSA protein during the stringent response. Journal of Biological Chemistry, 288(29), 21055-21064. https://doi.org/10.1074/jbc.M113.479998

Vancouver

Gummesson B, Lovmar M, Nyström T. A proximal promoter element required for positive transcriptional control by guanosine tetraphosphate and DKSA protein during the stringent response. Journal of Biological Chemistry. 2013 Jul 19;288(29):21055-21064. https://doi.org/10.1074/jbc.M113.479998

Author

Gummesson, Bertil ; Lovmar, Martin ; Nyström, Thomas. / A proximal promoter element required for positive transcriptional control by guanosine tetraphosphate and DKSA protein during the stringent response. In: Journal of Biological Chemistry. 2013 ; Vol. 288, No. 29. pp. 21055-21064.

Bibtex

@article{bc42a59551e84f6c9adace8a578ce5f4,
title = "A proximal promoter element required for positive transcriptional control by guanosine tetraphosphate and DKSA protein during the stringent response",
abstract = "Background: ppGpp/DksA regulate genes both positively and negatively during stringency. Results: Positive control by ppGpp/DksA is linked to RNA polymerase-promoter saturation kinetics dependent on the promoter's discriminator. Conclusion: Promoters harboring discriminators that make them easily saturated with RNA polymerase are controlled positively by ppGpp/DksA. Significance: The discriminator is a cis-acting element dictating the response of the promoter to alterations in ppGpp/DksA and RNA polymerase availability.",
author = "Bertil Gummesson and Martin Lovmar and Thomas Nystr{\"o}m",
year = "2013",
month = jul,
day = "19",
doi = "10.1074/jbc.M113.479998",
language = "English",
volume = "288",
pages = "21055--21064",
journal = "Journal of Biological Chemistry",
issn = "0021-9258",
publisher = "American Society for Biochemistry and Molecular Biology, Inc.",
number = "29",

}

RIS

TY - JOUR

T1 - A proximal promoter element required for positive transcriptional control by guanosine tetraphosphate and DKSA protein during the stringent response

AU - Gummesson, Bertil

AU - Lovmar, Martin

AU - Nyström, Thomas

PY - 2013/7/19

Y1 - 2013/7/19

N2 - Background: ppGpp/DksA regulate genes both positively and negatively during stringency. Results: Positive control by ppGpp/DksA is linked to RNA polymerase-promoter saturation kinetics dependent on the promoter's discriminator. Conclusion: Promoters harboring discriminators that make them easily saturated with RNA polymerase are controlled positively by ppGpp/DksA. Significance: The discriminator is a cis-acting element dictating the response of the promoter to alterations in ppGpp/DksA and RNA polymerase availability.

AB - Background: ppGpp/DksA regulate genes both positively and negatively during stringency. Results: Positive control by ppGpp/DksA is linked to RNA polymerase-promoter saturation kinetics dependent on the promoter's discriminator. Conclusion: Promoters harboring discriminators that make them easily saturated with RNA polymerase are controlled positively by ppGpp/DksA. Significance: The discriminator is a cis-acting element dictating the response of the promoter to alterations in ppGpp/DksA and RNA polymerase availability.

UR - http://www.scopus.com/inward/record.url?scp=84880550155&partnerID=8YFLogxK

U2 - 10.1074/jbc.M113.479998

DO - 10.1074/jbc.M113.479998

M3 - Journal article

C2 - 23749992

AN - SCOPUS:84880550155

VL - 288

SP - 21055

EP - 21064

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

SN - 0021-9258

IS - 29

ER -

ID: 165881718