Pseudoxylallemycins A-F, cyclic tetrapeptides with rare allenyl modifications isolated from Pseudoxylaria sp. X802: a competitor of fungus-growing termite cultivars

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Standard

Pseudoxylallemycins A-F, cyclic tetrapeptides with rare allenyl modifications isolated from Pseudoxylaria sp. X802 : a competitor of fungus-growing termite cultivars. / Guo, Huijuan; Kreuzenbeck, Nina B.; Otani, Saria; Garcia-Altares, Maria; Dahse, Hans-Martin; Weigel, Christiane; Aanen, Duur K.; Hertweck, Christian; Thomas-Poulsen, Michael; Beemelmanns, Christine.

In: Organic Letters, Vol. 18, No. 14, 2016, p. 3338-3341.

Research output: Contribution to journal › Letter › Research › peer-review

Harvard

Guo, H, Kreuzenbeck, NB, Otani, S, Garcia-Altares, M, Dahse, H-M, Weigel, C, Aanen, DK, Hertweck, C, Thomas-Poulsen, M & Beemelmanns, C 2016, 'Pseudoxylallemycins A-F, cyclic tetrapeptides with rare allenyl modifications isolated from Pseudoxylaria sp. X802: a competitor of fungus-growing termite cultivars', Organic Letters, vol. 18, no. 14, pp. 3338-3341. https://doi.org/10.1021/acs.orglett.6b01437

APA

Guo, H., Kreuzenbeck, N. B., Otani, S., Garcia-Altares, M., Dahse, H-M., Weigel, C., Aanen, D. K., Hertweck, C., Thomas-Poulsen, M., & Beemelmanns, C. (2016). Pseudoxylallemycins A-F, cyclic tetrapeptides with rare allenyl modifications isolated from Pseudoxylaria sp. X802: a competitor of fungus-growing termite cultivars. Organic Letters, 18(14), 3338-3341. https://doi.org/10.1021/acs.orglett.6b01437

Vancouver

Guo H, Kreuzenbeck NB, Otani S, Garcia-Altares M, Dahse H-M, Weigel C et al. Pseudoxylallemycins A-F, cyclic tetrapeptides with rare allenyl modifications isolated from Pseudoxylaria sp. X802: a competitor of fungus-growing termite cultivars. Organic Letters. 2016;18(14):3338-3341. https://doi.org/10.1021/acs.orglett.6b01437

Author

Guo, Huijuan ; Kreuzenbeck, Nina B. ; Otani, Saria ; Garcia-Altares, Maria ; Dahse, Hans-Martin ; Weigel, Christiane ; Aanen, Duur K. ; Hertweck, Christian ; Thomas-Poulsen, Michael ; Beemelmanns, Christine. / Pseudoxylallemycins A-F, cyclic tetrapeptides with rare allenyl modifications isolated from Pseudoxylaria sp. X802 : a competitor of fungus-growing termite cultivars. In: Organic Letters. 2016 ; Vol. 18, No. 14. pp. 3338-3341.

Bibtex

@article{5163669f17fe4749af70da8fa4448a44,
title = "Pseudoxylallemycins A-F, cyclic tetrapeptides with rare allenyl modifications isolated from Pseudoxylaria sp. X802: a competitor of fungus-growing termite cultivars",
abstract = "Based on fungus-fungus pairing assays and HRMS-based dereplication strategy, six new cyclic tetrapeptides, pseudoxylallemycins A-F (1-6), were isolated from the termite-associated fungus Pseudoxylaria sp. X802. Structures were characterized using NMR spectroscopy, HRMS, and Marfey's reaction. Pseudoxylallemycins B-D (2-4) possess a rare and chemically accessible allene moiety amenable for synthetic modifications, and derivatives A-D showed antimicrobial activity against Gram-negative human-pathogenic Pseudomonas aeruginosa and antiproliferative activity against human umbilical vein endothelial cells and K-562 cell lines.",
keywords = "Journal Article",
author = "Huijuan Guo and Kreuzenbeck, {Nina B.} and Saria Otani and Maria Garcia-Altares and Hans-Martin Dahse and Christiane Weigel and Aanen, {Duur K.} and Christian Hertweck and Michael Thomas-Poulsen and Christine Beemelmanns",
year = "2016",
doi = "10.1021/acs.orglett.6b01437",
language = "English",
volume = "18",
pages = "3338--3341",
journal = "Organic Letters",
issn = "1523-7060",
publisher = "American Chemical Society",
number = "14",

}

RIS

TY - JOUR

T1 - Pseudoxylallemycins A-F, cyclic tetrapeptides with rare allenyl modifications isolated from Pseudoxylaria sp. X802

T2 - a competitor of fungus-growing termite cultivars

AU - Guo, Huijuan

AU - Kreuzenbeck, Nina B.

AU - Otani, Saria

AU - Garcia-Altares, Maria

AU - Dahse, Hans-Martin

AU - Weigel, Christiane

AU - Aanen, Duur K.

AU - Hertweck, Christian

AU - Thomas-Poulsen, Michael

AU - Beemelmanns, Christine

PY - 2016

Y1 - 2016

N2 - Based on fungus-fungus pairing assays and HRMS-based dereplication strategy, six new cyclic tetrapeptides, pseudoxylallemycins A-F (1-6), were isolated from the termite-associated fungus Pseudoxylaria sp. X802. Structures were characterized using NMR spectroscopy, HRMS, and Marfey's reaction. Pseudoxylallemycins B-D (2-4) possess a rare and chemically accessible allene moiety amenable for synthetic modifications, and derivatives A-D showed antimicrobial activity against Gram-negative human-pathogenic Pseudomonas aeruginosa and antiproliferative activity against human umbilical vein endothelial cells and K-562 cell lines.

AB - Based on fungus-fungus pairing assays and HRMS-based dereplication strategy, six new cyclic tetrapeptides, pseudoxylallemycins A-F (1-6), were isolated from the termite-associated fungus Pseudoxylaria sp. X802. Structures were characterized using NMR spectroscopy, HRMS, and Marfey's reaction. Pseudoxylallemycins B-D (2-4) possess a rare and chemically accessible allene moiety amenable for synthetic modifications, and derivatives A-D showed antimicrobial activity against Gram-negative human-pathogenic Pseudomonas aeruginosa and antiproliferative activity against human umbilical vein endothelial cells and K-562 cell lines.

KW - Journal Article

U2 - 10.1021/acs.orglett.6b01437

DO - 10.1021/acs.orglett.6b01437

M3 - Letter

C2 - 27341414

VL - 18

SP - 3338

EP - 3341

JO - Organic Letters

JF - Organic Letters

SN - 1523-7060

IS - 14

ER -

ID: 169945955