Putting Warburg to work: how imaging of tumour acidosis could help predict metastatic potential in breast cancer
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Putting Warburg to work : how imaging of tumour acidosis could help predict metastatic potential in breast cancer. / Rolver, Michala Gylling; Pedersen, Stine Falsig.
In: British Journal of Cancer, Vol. 124, 2021, p. 1-2.Research output: Contribution to journal › Editorial › Research › peer-review
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TY - JOUR
T1 - Putting Warburg to work
T2 - how imaging of tumour acidosis could help predict metastatic potential in breast cancer
AU - Rolver, Michala Gylling
AU - Pedersen, Stine Falsig
PY - 2021
Y1 - 2021
N2 - Solid tumours are often highly acidic compared to normal tissue, and tumour extracellular acidosis contributes to multiple aspects of cancer progression. Now, Anemone et al. in this issue of the British Journal of Cancer provide in vivo evidence that the degree to which various breast cancer cell lines acidify their environment correlates with their ability to metastasise to the lungs. This indicates that measurements of tumour extracellular acidosis have the potential to become a clinical tool for assessing the risk of metastasis.
AB - Solid tumours are often highly acidic compared to normal tissue, and tumour extracellular acidosis contributes to multiple aspects of cancer progression. Now, Anemone et al. in this issue of the British Journal of Cancer provide in vivo evidence that the degree to which various breast cancer cell lines acidify their environment correlates with their ability to metastasise to the lungs. This indicates that measurements of tumour extracellular acidosis have the potential to become a clinical tool for assessing the risk of metastasis.
KW - PH
KW - MICROENVIRONMENT
KW - GROWTH
U2 - 10.1038/s41416-020-01171-2
DO - 10.1038/s41416-020-01171-2
M3 - Editorial
C2 - 33257840
VL - 124
SP - 1
EP - 2
JO - The British journal of cancer. Supplement
JF - The British journal of cancer. Supplement
SN - 0007-0920
ER -
ID: 254662560