Sceliphrolactam, a polyene macrocyclic lactam from a wasp-associated Streptomyces sp
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Sceliphrolactam, a polyene macrocyclic lactam from a wasp-associated Streptomyces sp. / Oh, Dong-Chan; Poulsen, Michael; Currie, Cameron R; Clardy, Jon.
In: Organic Letters, Vol. 13, No. 4, 2011, p. 752-755.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Sceliphrolactam, a polyene macrocyclic lactam from a wasp-associated Streptomyces sp
AU - Oh, Dong-Chan
AU - Poulsen, Michael
AU - Currie, Cameron R
AU - Clardy, Jon
PY - 2011
Y1 - 2011
N2 - A previously unreported 26-membered polyene macrocyclic lactam, sceliphrolactam, was isolated from an actinomycete, Streptomyces sp., associated with the mud dauber, Sceliphron caementarium. Sceliphrolactam's structure was determined by 1D- and 2D-NMR, MS, UV, and IR spectral analysis. Sceliphrolactam displays antifungal activity against amphotericin B-resistant Candida albicans (MIC = 4 µg/mL, 8.3 µM).
AB - A previously unreported 26-membered polyene macrocyclic lactam, sceliphrolactam, was isolated from an actinomycete, Streptomyces sp., associated with the mud dauber, Sceliphron caementarium. Sceliphrolactam's structure was determined by 1D- and 2D-NMR, MS, UV, and IR spectral analysis. Sceliphrolactam displays antifungal activity against amphotericin B-resistant Candida albicans (MIC = 4 µg/mL, 8.3 µM).
U2 - 10.1021/ol102991d
DO - 10.1021/ol102991d
M3 - Journal article
C2 - 21247188
VL - 13
SP - 752
EP - 755
JO - Organic Letters
JF - Organic Letters
SN - 1523-7060
IS - 4
ER -
ID: 33075263