Self-consuming innate immunity in Arabidopsis

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Standard

Self-consuming innate immunity in Arabidopsis. / Hofius, Daniel; Mundy, John; Petersen, Morten.

In: Autophagy, Vol. 5, No. 8, 2009, p. 1206-7.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Hofius, D, Mundy, J & Petersen, M 2009, 'Self-consuming innate immunity in Arabidopsis', Autophagy, vol. 5, no. 8, pp. 1206-7. https://doi.org/10.4161/auto.5.8.9892

APA

Hofius, D., Mundy, J., & Petersen, M. (2009). Self-consuming innate immunity in Arabidopsis. Autophagy, 5(8), 1206-7. https://doi.org/10.4161/auto.5.8.9892

Vancouver

Hofius D, Mundy J, Petersen M. Self-consuming innate immunity in Arabidopsis. Autophagy. 2009;5(8):1206-7. https://doi.org/10.4161/auto.5.8.9892

Author

Hofius, Daniel ; Mundy, John ; Petersen, Morten. / Self-consuming innate immunity in Arabidopsis. In: Autophagy. 2009 ; Vol. 5, No. 8. pp. 1206-7.

Bibtex

@article{808f319017bd11df8ed1000ea68e967b,
title = "Self-consuming innate immunity in Arabidopsis",
abstract = "Programmed cell death (PCD) associated with the pathogen-induced hypersensitive response (HR) is a hallmark of plant innate immunity. HR PCD is triggered upon recognition of pathogen effector molecules by host immune receptors either directly or indirectly via effector modulation of host targets. However, it has been unclear by which molecular mechanisms plants execute PCD during innate immune responses. We recently examined HR PCD in autophagy-deficient Arabidopsis knockout mutants (atg) and find that PCD conditioned by one class of plant innate immune receptors is suppressed in atg mutants. Intriguingly, HR triggered by another class of immune receptors with different genetic requirements is not compromised, indicating that only a specific subset of immune receptors engage the autophagy pathway for HR execution. Thus, our work provides a primary example of autophagic cell death associated with innate immune responses in eukaryotes as well as of prodeath functions for the autophagy pathway in plants.",
author = "Daniel Hofius and John Mundy and Morten Petersen",
year = "2009",
doi = "10.4161/auto.5.8.9892",
language = "English",
volume = "5",
pages = "1206--7",
journal = "Autophagy",
issn = "1554-8627",
publisher = "Taylor & Francis",
number = "8",

}

RIS

TY - JOUR

T1 - Self-consuming innate immunity in Arabidopsis

AU - Hofius, Daniel

AU - Mundy, John

AU - Petersen, Morten

PY - 2009

Y1 - 2009

N2 - Programmed cell death (PCD) associated with the pathogen-induced hypersensitive response (HR) is a hallmark of plant innate immunity. HR PCD is triggered upon recognition of pathogen effector molecules by host immune receptors either directly or indirectly via effector modulation of host targets. However, it has been unclear by which molecular mechanisms plants execute PCD during innate immune responses. We recently examined HR PCD in autophagy-deficient Arabidopsis knockout mutants (atg) and find that PCD conditioned by one class of plant innate immune receptors is suppressed in atg mutants. Intriguingly, HR triggered by another class of immune receptors with different genetic requirements is not compromised, indicating that only a specific subset of immune receptors engage the autophagy pathway for HR execution. Thus, our work provides a primary example of autophagic cell death associated with innate immune responses in eukaryotes as well as of prodeath functions for the autophagy pathway in plants.

AB - Programmed cell death (PCD) associated with the pathogen-induced hypersensitive response (HR) is a hallmark of plant innate immunity. HR PCD is triggered upon recognition of pathogen effector molecules by host immune receptors either directly or indirectly via effector modulation of host targets. However, it has been unclear by which molecular mechanisms plants execute PCD during innate immune responses. We recently examined HR PCD in autophagy-deficient Arabidopsis knockout mutants (atg) and find that PCD conditioned by one class of plant innate immune receptors is suppressed in atg mutants. Intriguingly, HR triggered by another class of immune receptors with different genetic requirements is not compromised, indicating that only a specific subset of immune receptors engage the autophagy pathway for HR execution. Thus, our work provides a primary example of autophagic cell death associated with innate immune responses in eukaryotes as well as of prodeath functions for the autophagy pathway in plants.

U2 - 10.4161/auto.5.8.9892

DO - 10.4161/auto.5.8.9892

M3 - Journal article

C2 - 19770586

VL - 5

SP - 1206

EP - 1207

JO - Autophagy

JF - Autophagy

SN - 1554-8627

IS - 8

ER -

ID: 17582668