Synthesis of 1,2-phenylenediamine capturing molecule for the detection of diacetyl
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- Synthesis of 1,2-phenylenediamine capturing molecule for the detection of diacetyl
Final published version, 696 KB, PDF document
Here we describe the design of 1,2-phenylenediamine capturing molecule and the synthesis steps necessary for its preparation. The designed 1,2-phenylenediamine derivative is able to capture diacetyl in solution, as shown by ESIMS, forming a chemical adduct, 1-4-quinoxaline. The methyl esters of diacetyl-adduct (DAA) and pentanedione-adduct (PDA) are incorporated to the lysines in BSA and the conjugate used for antibody screening and selection. In the research article is described an enzyme-linked immunosorbent assay developed to detect and quantify diacetyl in complex media.
Original language | English |
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Journal | Data in Brief |
Volume | 15 |
Pages (from-to) | 483-490 |
Number of pages | 8 |
ISSN | 2352-3409 |
DOIs | |
Publication status | Published - 2017 |
Externally published | Yes |
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ID: 200826959