The MAP kinase substrate MKS1 is a regulator of plant defense responses.

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

The MAP kinase substrate MKS1 is a regulator of plant defense responses. / Andreasson, Erik; Jenkins, Thomas; Brodersen, Peter; Thorgrimsen, Stephan; Petersen, Nikolaj H T; Zhu, Shijiang; Qiu, Jin-Long; Micheelsen, Pernille; Rocher, Anne; Petersen, Morten; Newman, Mari-Anne; Bjørn Nielsen, Henrik; Hirt, Heribert; Somssich, Imre; Mattsson, Ole; Mundy, John.

In: EMBO Journal, Vol. 24, No. 14, 2005, p. 2579-89.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Andreasson, E, Jenkins, T, Brodersen, P, Thorgrimsen, S, Petersen, NHT, Zhu, S, Qiu, J-L, Micheelsen, P, Rocher, A, Petersen, M, Newman, M-A, Bjørn Nielsen, H, Hirt, H, Somssich, I, Mattsson, O & Mundy, J 2005, 'The MAP kinase substrate MKS1 is a regulator of plant defense responses.', EMBO Journal, vol. 24, no. 14, pp. 2579-89. https://doi.org/10.1038/sj.emboj.7600737

APA

Andreasson, E., Jenkins, T., Brodersen, P., Thorgrimsen, S., Petersen, N. H. T., Zhu, S., Qiu, J-L., Micheelsen, P., Rocher, A., Petersen, M., Newman, M-A., Bjørn Nielsen, H., Hirt, H., Somssich, I., Mattsson, O., & Mundy, J. (2005). The MAP kinase substrate MKS1 is a regulator of plant defense responses. EMBO Journal, 24(14), 2579-89. https://doi.org/10.1038/sj.emboj.7600737

Vancouver

Andreasson E, Jenkins T, Brodersen P, Thorgrimsen S, Petersen NHT, Zhu S et al. The MAP kinase substrate MKS1 is a regulator of plant defense responses. EMBO Journal. 2005;24(14):2579-89. https://doi.org/10.1038/sj.emboj.7600737

Author

Andreasson, Erik ; Jenkins, Thomas ; Brodersen, Peter ; Thorgrimsen, Stephan ; Petersen, Nikolaj H T ; Zhu, Shijiang ; Qiu, Jin-Long ; Micheelsen, Pernille ; Rocher, Anne ; Petersen, Morten ; Newman, Mari-Anne ; Bjørn Nielsen, Henrik ; Hirt, Heribert ; Somssich, Imre ; Mattsson, Ole ; Mundy, John. / The MAP kinase substrate MKS1 is a regulator of plant defense responses. In: EMBO Journal. 2005 ; Vol. 24, No. 14. pp. 2579-89.

Bibtex

@article{706adcc0954011dd86a6000ea68e967b,
title = "The MAP kinase substrate MKS1 is a regulator of plant defense responses.",
abstract = "Arabidopsis MAP kinase 4 (MPK4) functions as a regulator of pathogen defense responses, because it is required for both repression of salicylic acid (SA)-dependent resistance and for activation of jasmonate (JA)-dependent defense gene expression. To understand MPK4 signaling mechanisms, we used yeast two-hybrid screening to identify the MPK4 substrate MKS1. Analyses of transgenic plants and genome-wide transcript profiling indicated that MKS1 is required for full SA-dependent resistance in mpk4 mutants, and that overexpression of MKS1 in wild-type plants is sufficient to activate SA-dependent resistance, but does not interfere with induction of a defense gene by JA. Further yeast two-hybrid screening revealed that MKS1 interacts with the WRKY transcription factors WRKY25 and WRKY33. WRKY25 and WRKY33 were shown to be in vitro substrates of MPK4, and a wrky33 knockout mutant was found to exhibit increased expression of the SA-related defense gene PR1. MKS1 may therefore contribute to MPK4-regulated defense activation by coupling the kinase to specific WRKY transcription factors.",
author = "Erik Andreasson and Thomas Jenkins and Peter Brodersen and Stephan Thorgrimsen and Petersen, {Nikolaj H T} and Shijiang Zhu and Jin-Long Qiu and Pernille Micheelsen and Anne Rocher and Morten Petersen and Mari-Anne Newman and {Bj{\o}rn Nielsen}, Henrik and Heribert Hirt and Imre Somssich and Ole Mattsson and John Mundy",
note = "Keywords: Amino Acid Motifs; Amino Acid Sequence; Arabidopsis Proteins; Gene Expression Profiling; Immunity, Natural; Immunohistochemistry; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Plants; Saccharomyces cerevisiae; Substrate Specificity; Two-Hybrid System Techniques",
year = "2005",
doi = "10.1038/sj.emboj.7600737",
language = "English",
volume = "24",
pages = "2579--89",
journal = "E M B O Journal",
issn = "0261-4189",
publisher = "Wiley-Blackwell",
number = "14",

}

RIS

TY - JOUR

T1 - The MAP kinase substrate MKS1 is a regulator of plant defense responses.

AU - Andreasson, Erik

AU - Jenkins, Thomas

AU - Brodersen, Peter

AU - Thorgrimsen, Stephan

AU - Petersen, Nikolaj H T

AU - Zhu, Shijiang

AU - Qiu, Jin-Long

AU - Micheelsen, Pernille

AU - Rocher, Anne

AU - Petersen, Morten

AU - Newman, Mari-Anne

AU - Bjørn Nielsen, Henrik

AU - Hirt, Heribert

AU - Somssich, Imre

AU - Mattsson, Ole

AU - Mundy, John

N1 - Keywords: Amino Acid Motifs; Amino Acid Sequence; Arabidopsis Proteins; Gene Expression Profiling; Immunity, Natural; Immunohistochemistry; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Plants; Saccharomyces cerevisiae; Substrate Specificity; Two-Hybrid System Techniques

PY - 2005

Y1 - 2005

N2 - Arabidopsis MAP kinase 4 (MPK4) functions as a regulator of pathogen defense responses, because it is required for both repression of salicylic acid (SA)-dependent resistance and for activation of jasmonate (JA)-dependent defense gene expression. To understand MPK4 signaling mechanisms, we used yeast two-hybrid screening to identify the MPK4 substrate MKS1. Analyses of transgenic plants and genome-wide transcript profiling indicated that MKS1 is required for full SA-dependent resistance in mpk4 mutants, and that overexpression of MKS1 in wild-type plants is sufficient to activate SA-dependent resistance, but does not interfere with induction of a defense gene by JA. Further yeast two-hybrid screening revealed that MKS1 interacts with the WRKY transcription factors WRKY25 and WRKY33. WRKY25 and WRKY33 were shown to be in vitro substrates of MPK4, and a wrky33 knockout mutant was found to exhibit increased expression of the SA-related defense gene PR1. MKS1 may therefore contribute to MPK4-regulated defense activation by coupling the kinase to specific WRKY transcription factors.

AB - Arabidopsis MAP kinase 4 (MPK4) functions as a regulator of pathogen defense responses, because it is required for both repression of salicylic acid (SA)-dependent resistance and for activation of jasmonate (JA)-dependent defense gene expression. To understand MPK4 signaling mechanisms, we used yeast two-hybrid screening to identify the MPK4 substrate MKS1. Analyses of transgenic plants and genome-wide transcript profiling indicated that MKS1 is required for full SA-dependent resistance in mpk4 mutants, and that overexpression of MKS1 in wild-type plants is sufficient to activate SA-dependent resistance, but does not interfere with induction of a defense gene by JA. Further yeast two-hybrid screening revealed that MKS1 interacts with the WRKY transcription factors WRKY25 and WRKY33. WRKY25 and WRKY33 were shown to be in vitro substrates of MPK4, and a wrky33 knockout mutant was found to exhibit increased expression of the SA-related defense gene PR1. MKS1 may therefore contribute to MPK4-regulated defense activation by coupling the kinase to specific WRKY transcription factors.

U2 - 10.1038/sj.emboj.7600737

DO - 10.1038/sj.emboj.7600737

M3 - Journal article

C2 - 15990873

VL - 24

SP - 2579

EP - 2589

JO - E M B O Journal

JF - E M B O Journal

SN - 0261-4189

IS - 14

ER -

ID: 6474536