Rasmus Hartmann-Petersen

Rasmus Hartmann-Petersen

Professor

ORCID: 0000-0002-4155-7791

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  1. Published

    Lynch syndrome, molecular mechanisms and variant classification

    Abildgaard, A. B., Nielsen, S., Bernstein, I., Stein, Amelie, Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2023, In: British Journal of Cancer. 128, 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  2. Published

    Co-Chaperones in Targeting and Delivery of Misfolded Proteins to the 26S Proteasome

    Abildgaard, A. B., Gersing, S. K., Larsen-Ledet, Sven, Nielsen, S. V., Stein, Amelie, Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2020, In: Biomolecules. 10, 8, 24 p., 1141.

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome

    Abildgaard, A. B., Stein, Amelie, Nielsen, S. V., Schultz-Knudsen, Katrine, Papaleo, E., Shrikhande, A., Hoffmann, Eva, Bernstein, I., Gerdes, Anne-Marie Axø, Takahashi, M., Ishioka, C., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2019, In: eLife. 8, 28 p., e49138 .

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    HSP70-binding motifs function as protein quality control degrons

    Abildgaard, A. B., Voutsinos, Vasileios, Petersen, S. D., Larsen, Fia Brunsgaard Valsted, Kampmeyer, Caroline, Johansson, Kristoffer Enøe, Stein, Amelie, Ravid, T., Andréasson, C., Jensen, M. K., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2023, In: Cellular and Molecular Life Sciences. 80, 1, 17 p., 32.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Evolution i overhalingsbanen

    Abildgaard, A. B., Hartmann-Petersen, Rasmus, Lindorff-Larsen, Kresten & Winther, Jakob R., 15 Dec 2017, In: Weekendavisen. 2017, 50, p. Ideer: 13 1 p.

    Research output: Contribution to journal › Contribution to newspaper - Feature article › Communication

  6. Published

    Molekylære stavefejl

    Abildgaard, A. B., Winther, Jakob R., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 28 Jan 2021, In: Weekendavisen, Ideer.

    Research output: Contribution to journal › Contribution to newspaper - Feature article › Communication

  7. Published

    VM i molekylære puslespil

    Abildgaard, A. B., Winther, Jakob R., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 16 Apr 2021, In: Weekendavisen: Ideer. 15, p. 11

    Research output: Contribution to journal › Contribution to newspaper - Feature article › Communication

  8. Published

    Characterisation of the nascent polypeptide-associated complex in fission yeast.

    Andersen, K. M., Semple, C. A. & Hartmann-Petersen, Rasmus, 2007, In: Molecular Biology Reports. 34, 4, p. 275-81 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Thioredoxin Txnl1/TRP32 Is a Redox-active Cofactor of the 26 S Proteasome

    Andersen, K. M., Klausen, L. K., Prag, S., Johnsen, A. H., Semple, C. A., Hendil, K. B. & Hartmann-Petersen, Rasmus, 2009, In: Journal of Biological Chemistry. 284, 22, p. 15246-15254

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Ubiquitin-binding proteins: similar, but different.

    Andersen, K. M., Hofmann, K. & Hartmann-Petersen, Rasmus, 2005, In: Essays in Biochemistry. 41, p. 49-67 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Txl1 and Txc1 are co-factors of the 26S proteasome in fission yeast

    Andersen, K. M., Jensen, C., Kriegenburg, F., Lauridsen, A. B., Gordon, C. & Hartmann-Petersen, Rasmus, 2011, In: Antioxidants & Redox Signaling. 14, 9, p. 1601-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Når proteiner får dødsstødet

    Andersen, K. M., Kristensen, P., Hendil, K. B. & Hartmann-Petersen, Rasmus, 2004, In: Aktuel Naturvidenskab. 5, p. 12-14

    Research output: Contribution to journal › Journal article › Research

  13. Published

    Bioinformatics analysis identifies several intrinsically disordered human E3 ubiquitin-protein ligases

    Boomsma, Wouter, Nielsen, S. V., Lindorff-Larsen, Kresten, Hartmann-Petersen, Rasmus & Ellgaard, Lars, 2016, In: PeerJ. 4, 18 p., e1725.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Proteasome nuclear import mediated by Arc3 can influence efficient DNA damage repair and mitosis in Schizosaccharomyces pombe

    Cabrera, R., Sha, Z., Vadakkan, T. J., Otero, J., Kriegenburg, F., Hartmann-Petersen, Rasmus, Dickinson, M. E. & Chang, E. C., 2010, In: Molecular Biology of the Cell. 21, 18, p. 3125-3136 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Understanding the Origins of Loss of Protein Function by Analyzing the Effects of Thousands of Variants on Activity and Abundance

    Cagiada, Matteo, Johansson, Kristoffer Enøe, Valanciute, A., Nielsen, S. V., Hartmann-Petersen, Rasmus, Yang, J. J., Fowler, D. M., Stein, Amelie & Lindorff-Larsen, Kresten, 2021, In: Molecular Biology and Evolution. 38, 8, p. 3235-3246

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Discovering functionally important sites in proteins

    Cagiada, Matteo, Bottaro, S., Lindemose, Søren, Schenstrøm, S. M., Stein, Amelie, Hartmann-Petersen, Rasmus & Lindorff-Larsen, Kresten, 2023, In: Nature Communications. 14, 1, 13 p., 4175.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    PRKN-linked familial Parkinson’s disease: cellular and molecular mechanisms of disease-linked variants

    Clausen, L., Okarmus, J., Voutsinos, Vasileios, Meyer, M., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2024, In: Cellular and Molecular Life Sciences. 81, 1, 17 p., 223.

    Research output: Contribution to journal › Review › Research › peer-review

  18. Published

    A mutational atlas for Parkin proteostasis

    Clausen, L., Voutsinos, Vasileios, Cagiada, Matteo, Johansson, Kristoffer Enøe, Grønbæk-Thygesen, Martin, Nariya, S., Powell, R. L., Have, M. K. N., Østergaard, Vibe Hallundbæk, Stein, Amelie, Fowler, D. M., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2024, In: Nature Communications. 15, 1, 17 p., 1541.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Protein stability and degradation in health and disease

    Bjørnkjær, Lene, Abildgaard, A. B., Gersing, S. K., Stein, Amelie, Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2019, Molecular Chaperones in Human Disorders. Donev, R. (ed.). Academic Press, p. 61-83 (Advances in Protein Chemistry and Structural Biology, Vol. 114).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  20. Published

    Folliculin variants linked to Birt-Hogg-Dubé syndrome are targeted for proteasomal degradation

    Bjørnkjær, Lene, Stein, Amelie, Grønbæk-Thygesen, Martin, Nygaard, L., Søltoft, C. L., Nielsen, S. V., Lisby, Michael, Ravid, T., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2020, In: PLOS Genetics. 16, 11, 28 p., e1009187.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    A context-dependent and disordered ubiquitin-binding motif

    Dreier, Jesper Elmsted, Prestel, Andreas, Martins, J. M., Brøndum, S. S., Nielsen, Olaf, Garbers, Anna Engstrøm, Suga, H., Boomsma, Wouter, Rogers, Joseph Matthew, Hartmann-Petersen, Rasmus & Kragelund, Birthe Brandt, 2022, In: Cellular and molecular life sciences : CMLS. 79, 9, 21 p., 484.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    A comprehensive map of human glucokinase variant activity

    Gersing, S., Cagiada, Matteo, Gebbia, M., Gjesing, A. P., Coté, A. G., Seesankar, G., Li, R., Tabet, D., Weile, J., Stein, Amelie, Gloyn, A. L., Hansen, Torben, Roth, F. P., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2023, In: Genome Biology. 24, 1, 23 p., 97.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Characterizing glucokinase variant mechanisms using a multiplexed abundance assay

    Gersing, S., Schulze, Thea Klarsø, Cagiada, Matteo, Stein, Amelie, Roth, F. P., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2024, In: Genome Biology. 25, 1, 22 p., 98.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Mapping the degradation pathway of a disease-linked aspartoacylase variant

    Gersing, S. K., Wang, Y., Grønbæk-Thygesen, Martin, Kampmeyer, Caroline, Bjørnkjær, Lene, Willemoës, Martin, Andréasson, C., Stein, Amelie, Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2021, In: PLOS Genetics. 17, 4, 28 p., e1009539.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    14-fold increased prevalence of rare glucokinase gene variant carriers in unselected Danish patients with newly diagnosed type 2 diabetes

    Gjesing, A. P., Engelbrechtsen, L., Cathrine B. Thuesen, A., Have, C. T., Hollensted, M., Grarup, N., Linneberg, A., Steen Nielsen, J., Christensen, L. B., Thomsen, R. W., Johansson, K. E., Cagiada, M., Gersing, S., Hartmann-Petersen, R., Lindorff-Larsen, K., Vaag, A., Sørensen, H. T., Brandslund, I., Beck-Nielsen, H., Pedersen, O. & 2 others, Rungby, Jørgen & Hansen, Torben, 2022, In: Diabetes Research and Clinical Practice. 194, 9 p., 110159.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. E-pub ahead of print

    Destabilization and Degradation of a Disease-Linked PGM1 Protein Variant

    Gouliaev, F., Jonsson, Nicolas, Gersing, S., Lisby, Michael, Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2024, (E-pub ahead of print) In: Biochemistry.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Cellular and molecular mechanisms of aspartoacylase and its role in Canavan disease

    Grønbæk-Thygesen, Martin & Hartmann-Petersen, Rasmus, 2024, In: Cell and Bioscience. 14, 1, 33 p., 45.

    Research output: Contribution to journal › Review › Research › peer-review

  28. Published

    Deep mutational scanning reveals a correlation between degradation and toxicity of thousands of aspartoacylase variants

    Grønbæk-Thygesen, Martin, Voutsinos, Vasileios, Johansson, Kristoffer Enøe, Schulze, Thea Klarsø, Cagiada, Matteo, Pedersen, Line, Clausen, L., Nariya, S., Powell, R. L., Stein, Amelie, Fowler, D. M., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2024, In: Nature Communications. 15, 1, 18 p., 4026.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    The moonlighting of RAD23 in DNA repair and protein degradation

    Grønbæk-Thygesen, Martin, Kampmeyer, Caroline, Hofmann, K. & Hartmann-Petersen, Rasmus, 2023, In: Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1866, 2, 16 p., 194925.

    Research output: Contribution to journal › Review › Research › peer-review

  30. Published

    Encyclopaedia of Science and Technology

    Hartmann-Petersen, P., Gerrans, G. C. & Hartmann-Petersen, Rasmus, 2004, 2 ed. NAE Publishers. 301 p.

    Research output: Book/Report › Book › Communication

  31. Published

    Quaternary structure of the ATPase complex of human 26S proteasomes determined by chemical cross-linking.

    Hartmann-Petersen, Rasmus, Tanaka, K. & Hendil, K. B., 2001, In: Archives of Biochemistry and Biophysics. 386, 1, p. 89-94 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Proteins interacting with the 26S proteasome.

    Hartmann-Petersen, Rasmus & Gordon, C., 2004, In: Cellular and molecular life sciences : CMLS. 61, 13, p. 1589-95 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Individual cell motility studied by time-lapse video recording: influence of experimental conditions.

    Hartmann-Petersen, Rasmus, Walmod, P. S., Berezin, A., Berezin, V. & Bock, E., 2000, In: Cytometry. Part B: Clinical Cytometry. 40, 4, p. 260-70 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Ubiquitin binding proteins protect ubiquitin conjugates from disassembly.

    Hartmann-Petersen, Rasmus, Hendil, K. B. & Gordon, C., 2003, In: FEBS Letters. 535, 1-3, p. 77-81 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Transferring substrates to the 26S proteasome.

    Hartmann-Petersen, Rasmus, Seeger, M. & Gordon, C., 2003, In: TIBS -Trends in Biochemical Sciences. Regular ed.. 28, 1, p. 26-31 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    The Ubx2 and Ubx3 cofactors direct Cdc48 activity to proteolytic and nonproteolytic ubiquitin-dependent processes.

    Hartmann-Petersen, Rasmus, Wallace, M., Hofmann, K., Koch, G., Johnsen, A. H., Hendil, K. B. & Gordon, C., 2004, In: Current Biology. 14, 9, p. 824-8 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Meeting report: The ubiqitin family gathers

    Hartmann-Petersen, Rasmus, 2004, In: The Biochemist. 26, p. 34-36

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    UBA domain containing proteins in fission yeast.

    Hartmann-Petersen, Rasmus, Semple, C. A. M., Ponting, C. P., Hendil, K. B. & Gordon, C., 2003, In: International Journal of Biochemistry & Cell Biology. 35, 5, p. 629-36 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Ubiquitin-proteasome system. Proteins interacting with the 26S proteasome

    Hartmann-Petersen, Rasmus & Gordon, C., 2004, In: Cellular and Molecular Life Sciences. 61, p. 1589-1595

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Integral UBL domain proteins: a family of proteasome interacting proteins.

    Hartmann-Petersen, Rasmus & Gordon, C., 2004, In: Seminars in Cell and Developmental Biology. 15, 2, p. 247-59 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Quantifying protein-protein interactions in the ubiquitin pathway by surface plasmon resonance.

    Hartmann-Petersen, Rasmus & Gordon, C., 2005, In: Methods in Enzymology. 399, p. 164-77 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Protein degradation: recognition of ubiquitinylated substrates.

    Hartmann-Petersen, Rasmus & Gordon, C., 2004, In: Current Biology. 14, 18, p. R754-6

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    The 20S proteasome as an assembly platform for the 19S regulatory complex

    Hendil, K. A. B., Kriegenburg, F., Tanaka, K., Murata, S., Lauridsen, A. B., Johnsen, A. H. & Hartmann-Petersen, Rasmus, 2009, In: Journal of Molecular Biology. 394, 2, p. 320-328 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    26 S proteasomes function as stable entities.

    Hendil, K. B., Hartmann-Petersen, Rasmus & Tanaka, K., 2002, In: Journal of Molecular Biology. 315, 4, p. 627-36 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Proteasomes: a complex story.

    Hendil, K. B. & Hartmann-Petersen, Rasmus, 2004, In: Current Protein and Peptide Science. 5, 3, p. 135-51 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Phosphorylation of Schizosaccharomyces pombe Dss1 mediates direct binding to the ubiquitin-ligase Dma1 in vitro

    Jacobsen, Nina Louise, Bloch, Magnus Borup, Millard, P. S., Ruidiaz, Sarah Frederiksen, Elsborg, Jonas Damgaard, Boomsma, Wouter, Hendus-Altenburger, R., Hartmann-Petersen, Rasmus & Kragelund, Birthe Brandt, 2023, In: Protein Science. 32, 9, 16 p., e4733.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Classifying disease-associated variants using measures of protein activity and stability

    Jepsen, M. M., Fowler, D. M., Hartmann-Petersen, Rasmus, Stein, Amelie & Lindorff-Larsen, Kresten, 2020, Protein Homeostasis Diseases: Mechanisms and Novel Therapies. Pey, A. L. (ed.). Elsevier, p. 91-107

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  48. Published

    Prediction of Quality-control Degradation Signals in Yeast Proteins

    Johansson, Kristoffer Enøe, Mashahreh, B., Hartmann-Petersen, Rasmus, Ravid, T. & Lindorff-Larsen, Kresten, 2023, In: Journal of Molecular Biology. 435, 2, 9 p., 167915.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Adrm1, a putative cell adhesion regulating protein, is a novel proteasome-associated factor.

    Jørgensen, J. P., Lauridsen, A., Kristensen, P., Dissing, K., Johnsen, A. H., Hendil, K. B. & Hartmann-Petersen, Rasmus, 2006, In: Journal of Molecular Biology. 360, 5, p. 1043-52 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Lysine deserts prevent adventitious ubiquitylation of ubiquitin-proteasome components

    Kampmeyer, Caroline, Grønbæk-Thygesen, Martin, Oelerich, N., Tatham, M. H., Cagiada, Matteo, Lindorff-Larsen, K., Boomsma, Wouter, Hofmann, K. & Hartmann-Petersen, Rasmus, 2023, In: Cellular and Molecular Life Sciences. 80, 6, 18 p., 143.

    Research output: Contribution to journal › Journal article › Research › peer-review

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