Genevieve Thon
Associate Professor
Functional Genomics
Ole Maaløes Vej 5
2200 København N.
- Published
Mating-type cassettes: structure, switching and silencing
Arcangioli, B. & Thon, Genevieve, 2003, The Molecular Biology of Schizosaccharomyces pombe.. Springer, p. 129-148Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research
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Functional divergence between histone deacetylases in fission yeast by distinct cellular localization and in vivo specificity
Bjerling, P., Silverstein, R., Thon, Genevieve, Caudy, A., Grewal, S. & Ekwall, K., 2002, In: Mol. Cell. Biol.. 22, p. 2170-2181Research output: Contribution to journal › Journal article › Research › peer-review
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A novel type of silencing factor, Clr2, is necessary for transcriptional silencing at various chromosomal locations in the fission yeast Schizosaccharomyces pombe
Bjerling, P., Ekwall, K., Egel, Richard & Thon, Genevieve, 2004, In: Nucleic Acids Research. 32, 15, p. 4421-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic selection and DNA sequences of 4.5S RNA homologs
Brown, Stanley, Thon, Genevieve & Tolentino, E., 1989, In: Journal of Bacteriology. 171, 12, p. 6517-20 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Integrity of a heterochromatic domain ensured by its boundary elements
Charlton, Sebastian Jespersen, Jørgensen, M. M. & Thon, Genevieve, 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 35, p. 21504-21511 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Theoretical analysis of epigenetic cell memory by nucleosome modification
Dodd, I. B., Micheelsen, M. A., Sneppen, Kim & Thon, Genevieve, 2007, In: Cell. 129, 4, p. 813-22 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic analysis of Schizosaccharomyces pombe
Ekwall, K. & Thon, Genevieve, Aug 2017, In: Cold Spring Harbor Protocols. 2017, 8, p. 593-605 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ethyl methanesulfonate mutagenesis in Schizosaccharomyces pombe
Ekwall, K. & Thon, Genevieve, Aug 2017, In: Cold Spring Harbor Protocols. 2017, 8, p. 643-646 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Setting up Schizosaccharomyces pombe crosses/matings
Ekwall, K. & Thon, Genevieve, Jul 2017, In: Cold Spring Harbor Protocols. 2017, 7, p. 533-536 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Spore analysis and tetrad dissection of Schizosaccharomyces pombe
Ekwall, K. & Thon, Genevieve, Jul 2017, In: Cold Spring Harbor Protocols. 2017, 7, p. 541-544 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Selecting Schizosaccharomyces pombe diploids
Ekwall, K. & Thon, Genevieve, Jul 2017, In: Cold Spring Harbor Protocols. 2017, 7, p. 537-540 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mating-type determination in Schizosaccharomyces pombe
Ekwall, K. & Thon, Genevieve, Aug 2017, In: Cold Spring Harbor Protocols. 2017, 8, p. 641-642 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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RNAi and heterochromatin repress centromeric meiotic recombination
Ellermeier, C., Higuchi, E. C., Phadnis, N., Holm, L., Geelhood, J. L., Thon, Genevieve & Smith, G. R., 11 May 2010, In: Proceedings of the National Academy of Sciences USA (PNAS). 107, 19, p. 8701-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Euchromatin factors HULC and Set1C affect heterochromatin organization and mating-type switching in fission yeast Schizosaccharomyces pombe
Esquivel-Chávez, A., Maki, T., Tsubouchi, H., Handa, T., Kimura, H., Haber, J. E., Thon, Genevieve & Iwasaki, H., 2022, In: Genes and Genetic Systems. 97, 3, p. 123-138 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evolutionary-conserved telomere-linked helicase genes of fission yeast are repressed by silencing factors, RNAi components and the telomere-binding protein Taz1
Hansen, K. R., Ibarra, P. T. & Thon, Genevieve, 2006, In: Nucleic Acids Research. 34, 1, p. 78-88Research output: Contribution to journal › Journal article › Research › peer-review
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H3K9me-independent gene silencing in fission yeast heterochromatin by Clr5 and histone deacetylases
Hansen, K. R., Hazan, I., Shanker, S., Watt, S., Hansen, J. V., Bähler, J., Martienssen, R. A., Partridge, J. F., Cohen, A. & Thon, Genevieve, 2011, In: P L o S Genetics. 7, 1, 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Global Effects on Gene Expression in Fission Yeast by Silencing and RNA Interference Machineries
Hansen, K. R., Burns, G., Mata, J., Volpe, T. A., Martienssen, R. A., Bähler, J. & Thon, Genevieve, 2005, In: Molecular and Cellular Biology. 25, 2, p. 590-601Research output: Contribution to journal › Journal article › Research › peer-review
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New romance between RNA degradation pathways: Mmi1 and RNAi meet on heterochromatic islands
Holm, L. R. & Thon, Genevieve, 2012, In: E M B O Journal. 31, p. 2242 - 2243 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dependency of Heterochromatin Domains on Replication Factors
Jahn, L. J., Mason, B., Brøgger, Peter, Toteva, T., Nielsen, D. K. & Thon, Genevieve, 2018, In: G3: Genes, Genomes, Genetics (Bethesda). 8, 2, p. 477-489 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Two portable recombination enhancers direct donor choice in fission yeast heterochromatin
Jakociunas, T., Holm, L. R., Hansen, J. V., Trusina, Ala & Thon, Genevieve, 2013, In: P L o S Genetics. 9, 10, 14 p., e1003762.Research output: Contribution to journal › Journal article › Research › peer-review
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Subnuclear relocalization and silencing of a chromosomal region by an ectopic ribosomal DNA repeat
Jakociunas, T., Domange Jordö, M. E., Mebarek, M. A., Bünner, C. M., Hansen, J. V., Oddershede, L. B. & Thon, Genevieve, 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 47, p. E4465-E4473 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure of the replication regulator Sap1 reveals functionally important interfaces
Jørgensen, M. L. M., Ekundayo, B., Zaratiegui, M., Skriver, Karen, Thon, Genevieve & Schalch, T., 2018, In: Scientific Reports. 8, 9 p., 10930.Research output: Contribution to journal › Journal article › Research › peer-review
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Targeting of SUMO substrates to a Cdc48-Ufd1-Npl4 segregase and STUbL pathway in fission yeast
Køhler, J. B., Tammsalu, T., Jørgensen, M. L. M., Steen, N., Hay, R. T. & Thon, Genevieve, 2015, In: Nature Communications. 6, 14 p., 8827.Research output: Contribution to journal › Journal article › Research › peer-review
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Concerted action of the Ubiquitin-Fusion Degradation Protein 1 (Ufd1) and Sumo-Targeted Ubiquitin Ligases (STUbLs) in the DNA-damage response
Køhler, J. B., Jørgensen, M. L. M., Beinoraite, G., Thorsen, M. & Thon, Genevieve, 2013, In: P L o S One. 8, 11, 15 p., e80442.Research output: Contribution to journal › Journal article › Research › peer-review
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Fission yeast Swi2 designates cell-type specific donor and stimulates Rad51-driven strand exchange for mating-type switching
Maki, T., Thon, Genevieve & Iwasaki, H., 2023, In: Nucleic acids symposium series. 51, 8, 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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New insights into donor directionality of mating-type switching in Schizosaccharomyces pombe
Maki, T., Ogura, N., Haber, J. E., Iwasaki, H. & Thon, Genevieve, May 2018, In: PLOS Genetics. 14, 5, p. 1-25 e1007424.Research output: Contribution to journal › Journal article › Research › peer-review
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Establishment of heterochromatin in domain-size-dependent bursts
Nickels, Jan Fabio, Edwards, A. K., Charlton, Sebastian Jespersen, Mortensen, A. M., Hougaard, S. C. L., Trusina, Ala, Sneppen, Kim & Thon, Genevieve, 13 Apr 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 15, 11 p., e2022887118.Research output: Contribution to journal › Journal article › Research › peer-review
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The transcription factor Atf1 lowers the transition barrier for nucleosome-mediated establishment of heterochromatin
Nickels, Jan Fabio, Della-Rosa, M. E., Miguelez Goyeneche, I., Charlton, Sebastian Jespersen, Sneppen, Kim & Thon, Genevieve, 2022, In: Cell Reports. 39, 7, 17 p., 110828.Research output: Contribution to journal › Journal article › Research › peer-review
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The fission yeast ubiquitin-conjugating enzymes UbcP3, Ubc15, and Rhp6 affect transcriptional silencing of the mating-type region
Nielsen, I. S., Nielsen, Olaf, Murray, J. M. & Thon, Genevieve, 1 Aug 2002, In: Eukaryotic Cell (Online Edition). 1, 4, p. 613-25 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nucleation and spreading of a heterochromatic domain in fission yeast
Obersriebnig, M. J., Pallesen, E. M. H., Sneppen, Kim, Trusina, Ala & Thon, Genevieve, 2016, In: Nature Communications. 7, 11 p., 11518.Research output: Contribution to journal › Journal article › Research › peer-review
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The Clr7 and Clr8 Directionality Factors and the Pcu4 Cullin Mediate Heterochromatin Formation in the Fission Yeast Schizosaccharomyces pombe
Thon, Genevieve, Hansen, K. R., Altes, S. P., Sidhu, D., Singh, G., Verhein-Hansen, J., Bonaduce, M. J. & Klar, A. J. S., 2005, In: Genetics. 171, 4, p. 1583-1595Research output: Contribution to journal › Journal article › Research › peer-review
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Localization and properties of a silencing element near the mat3-M mating-type cassette of Schizosaccharomyces pombe
Thon, Genevieve, Bjerling, P. & Nielsen, I. S., 1999, In: Genetics. 151, p. 945-963Research output: Contribution to journal › Journal article › Research › peer-review
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Epigenetic inheritance of transcriptional silencing and switching competence in fission yeast
Thon, Genevieve & Friis, T., 1997, In: Genetics. 145, p. 685-696Research output: Contribution to journal › Journal article › Research › peer-review
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The clr1 locus regulates the expression of the cryptic mating-type loci of fission yeast
Thon, Genevieve & Klar, A., 1992, In: Genetics. 131, 2, p. 287-296 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Directionality of fission yeast mating-type interconversion is controlled by the location of the donor loci
Thon, Genevieve, 1993, In: Genetics. 134, 4, p. 1045-1054 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Histone modifications: Cycling with chromosomal replication
Thon, Genevieve, 2008, In: Current Biology. 18, 9, p. 380-382 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mating-type switching by homology-directed recombinational repair: a matter of choice
Thon, Genevieve, Maki, T., Haber, J. E. & Iwasaki, H., 2019, In: Current Genetics. 65, 2, p. 351-362Research output: Contribution to journal › Journal article › Research › peer-review
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Antigenic diversity by the recombination of pseudogenes
Thon, Genevieve, Baltz, T. & Eisen, H., 1989, In: Genes & Development. 3, 8, p. 1247-1254 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Three additional linkage groups that repress transcription and meiotic recombination in the mating-type region of Schizosaccharomyces pombe
Thon, Genevieve, Cohen, A. & Klar, A., 1994, In: Genetics. 138, 1, p. 29-38 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Trypanosome variable surface glycoproteins: composite genes and order of expression
Thon, Genevieve, Baltz, T., Giroud, C. & Eisen, H., 1990, In: Genes & Development. 4, 8, p. 1374-1383 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Competing to destroy: a fight between two RNA-degradation systems
Thon, Genevieve, 2008, In: Nature Structural and Molecular Biology. 15, 10, p. 1001-2 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Expression-state boundaries in the mating-type region of fission yeast
Thon, Genevieve, Bjerling, K. P., Bünner, C. M. & Hansen, J. V., 2002, In: Genetics. 161, p. 611-622Research output: Contribution to journal › Journal article › Research › peer-review
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Four chromo-domain proteins of Schizosaccharomyces pombe differentially repress transcription at various chromosomal locations
Thon, Genevieve & Hansen, J. V., 2000, In: Genetics. 155, p. 551-568Research output: Contribution to journal › Journal article › Research › peer-review
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Mediator regulates non-coding RNA transcription at fission yeast centromeres
Thorsen, M., Hansen, H., Venturi, M., Holmberg, Steen & Thon, Genevieve, 2012, In: Epigenetics & Chromatin. 5, p. 1-10 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Anomalous Diffusion in Living Yeast Cells
Tolic-Norrelykke, I. M., Munteanu, E. L., Thon, Genevieve, Oddershede, L. B. & Berg-Sorensen, K., 2004, In: Physical Review Letters. Vol. 93 No. 7, August 13th, p. Artikel No. 078102Research output: Contribution to journal › Journal article › Research › peer-review
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Positioning and elongation of the fission yeast spindle by microtubule-based pushing
Tolic-Norrelykke, I. M., Sacconi, L., Thon, Genevieve & Pavone, F. S., 2004, In: Current Biology. Vol. 14. No. 13., p. 1181-1186Research output: Contribution to journal › Journal article › Research › peer-review
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Establishment of expression-state boundaries by Rif1 and Taz1 in fission yeast
Toteva, T., Mason, B., Kanoh, Y., Brøgger, P., Green, D., Hansen, J. V., Masai, H. & Thon, Genevieve, 31 Jan 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 5, p. 1093-1098 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Role of the fission yeast SUMO E3 ligase Pli1p in centromere and telomere maintenance
Xhemalce, B., Seeler, J. S., Thon, Genevieve, Dejean, A. & Arcangioli, B., 2004, In: EMBO Journal. Vol. 23 No. 19, p. 3844-3853Research output: Contribution to journal › Journal article › Research › peer-review
ID: 13944
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Two portable recombination enhancers direct donor choice in fission yeast heterochromatin
Research output: Contribution to journal › Journal article › Research › peer-review
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1233
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H3K9me-independent gene silencing in fission yeast heterochromatin by Clr5 and histone deacetylases
Research output: Contribution to journal › Journal article › Research › peer-review
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1192
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Mediator regulates non-coding RNA transcription at fission yeast centromeres
Research output: Contribution to journal › Journal article › Research › peer-review
Published