Competing to destroy: a fight between two RNA-degradation systems
Research output: Contribution to journal › Journal article › Research › peer-review
The Argonaute-1 (Ago1) protein bound to small interfering RNAs (siRNAs) directs heterochromatin formation in fission yeast. A high-throughput sequencing approach reveals that the composition of the Ago1-bound siRNA population is sensitive to the noncanonical poly(A) polymerase Cid14, indicating that the RNA-interference and Cid14-TRAMP RNA-degradation pathways compete for substrates in fission yeast.
| Original language | English |
|---|---|
| Journal | Nature Structural and Molecular Biology |
| Volume | 15 |
| Issue number | 10 |
| Pages (from-to) | 1001-2 |
| Number of pages | 2 |
| ISSN | 1545-9993 |
| DOIs | |
| Publication status | Published - 2008 |
Bibliographical note
KEYWORDS: Protein Binding; RNA Stability; RNA, Small Interfering; Schizosaccharomyces
ID: 9179081