Jakob R. Winther
Professor
Biomolecular Sciences
Ole Maaløes Vej 5
2200 København N.
- 2010
- Published
Kinetic and thermodynamic properties of two barley thioredoxin h isozymes, HvTrxh1 and HvTrxh2
Maeda, K., Hägglund, Per Mårten, Björnberg, O., Winther, Jakob R. & Svensson, B., 2010, In: FEBS Letters. 584, 15, p. 3376-3380 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thiol-Disulfide Exchange between Glutaredoxin and Glutathione
Iversen, R., Andersen, P. A., Jensen, K. S., Winther, Jakob R. & Sigurskjold, B. W., 2010, In: Biochemistry. 49, 4, p. 810-820 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
An introduction to methods for analyzing thiols and disulfides: Reactions, reagents, and practical considerations
Hansen, R. E. & Winther, Jakob R., 2009, In: Analytical Biochemistry. 394, 2, p. 147-58 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinetic and Thermodynamic Aspects of Cellular Thiol-Disulfide Redox Regulation
Jensen, K. S., Hansen, R. E. & Winther, Jakob R., 2009, In: Antioxidants & Redox Signaling. 11, 5, p. 1047-1058Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantifying the global cellular thiol-disulfide status
Hansen, R. E., Roth, D. & Winther, Jakob R., 2009, In: Proceedings of the National Academy of Science of the United States of America. 106, 2, p. 422-427 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
High-resolution imaging of redox signaling in live cells through an oxidation-sensitive yellow fluorescent protein
Maulucci, G., Labate, V., Mele, M., Panieri, E., Arcovito, G., Galeotti, T., Østergaard, H., Winther, Jakob R., De Spirito, M. & Pani, G., 2008, In: Science Signaling. 1, 43, p. pl3 1-15 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutations in the RAM network confer resistance to the thiol oxidant 4,4'-dipyridyl disulfide
López-Mirabal, H. R., Winther, Jakob R., Thorsen, M. & Kielland-Brandt, M. C., 2008, In: Molecular Genetics and Genomics. 279, 6, p. 629-42 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxidant resistance in a yeast mutant deficient in the Sit4 phosphatase
López-Mirabal, H. R., Winther, Jakob R. & Kielland-Brandt, M. C., 2008, In: Current Genetics. 53, 5, p. 275-86 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
Cytoplasmic glutathione redox status determines survival upon exposure to the thiol-oxidant 4,4'-dipyridyl disulfide.
López-Mirabal, H. R., Thorsen, M., Kielland-Brandt, M. C., Toledano, M. B. & Winther, Jakob R., 2007, In: FEMS Yeast Research. 7, 3, p. 391-403 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Erv2p: characterization of the redox behavior of a yeast sulfhydryl oxidase.
Wang, W., Winther, Jakob R. & Thorpe, C., 2007, In: Biochemistry. 46, 11, p. 3246-54 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic interaction between the ero1-1 and leu2 mutations in Saccharomyces cerevisiae.
López-Mirabal, H. R., Winther, Jakob R. & Kielland-Brandt, M. C., 2007, In: Bioscience, Biotechnology, and Biochemistry. 71, 12, p. 2934-42 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantification of protein thiols and dithiols in the picomolar range using sodium borohydride and 4,4'-dithiodipyridine.
Hansen, R. E., Østergaard, H., Nørgaard, P. & Winther, Jakob R., 2007, In: Analytical Biochemistry. 363, 1, p. 77-82 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Redox characteristics of the eukaryotic cytosol.
López-Mirabal, H. R. & Winther, Jakob R., 2007, In: BBA General Subjects.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure of glutaredoxin Grx1p C30S mutant from yeast.
Håkansson, K. O. & Winther, Jakob R., 2007, In: Acta Crystallographica. Section D: Biological Crystallography. 63, Pt 3, p. 288-94 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The thiol oxidant dipyridyl disulfide can supply the PDI-Ero1p pathway with additional oxidative equivalents.
López-Mirabal, H. R. & Winther, Jakob R., 2007, In: Antonie van Leeuwenhoek. International Journal of General and Molecular Microbiology. 92, 4, p. 463-72 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Crystallization of mutant forms of glutaredoxin Grx1p from yeast
Håkansson, K. O., Østergaard, H. & Winther, Jakob R., 2006, In: Acta Crystallographica. Section F : Structural Biology and Crystallization Communications. 62, 9, p. 920-922Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence that translation reinitiation leads to a partially functional Menkes protein containing two copper-binding sites
Paulsen, M., Lund, C., Akram, Z., Winther, Jakob R., Horn, N. & Møller, L. B., 2006, In: American Journal of Human Genetics. 79, 2, p. 214-29 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Measuring intracellular redox conditions using GFP-based sensors
Björnberg, O., Ostergaard, H. & Winther, Jakob R., 2006, In: Antioxidants & Redox Signaling. 8, 3-4, p. 354-61 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanistic insight provided by glutaredoxin within a fusion to redox-sensitive yellow fluorescent protein
Björnberg, O., Østergaard, H. & Winther, Jakob R., 2006, In: Biochemistry. 45, 7, p. 2362-71 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Increasing the reactivity of an artificial dithiol-bisulfide pair through modification of the electrostatic milieu
Hansen, R. E., Østergaard, H. & Winther, Jakob R., 2005, In: Biochemistry.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increasing the reactivity of an artificial dithiol-disulfide pair through modification of the electrostatic milieu
Hansen, R. E., Østergaard, H. & Winther, Jakob R., 2005, In: Biochemistry. 44, 15, p. 5899-906 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
Fluorometric polyethyleneglycol-peptide hybrid substrates for quantitative assay of protein disulfide isomerase
Christiansen, C., Hilaire, P. M. S. & Winther, Jakob R., 2004, In: Analytical Biochemistry. 333, 1, p. 148-155 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Monitoring disulfide bond formation in the eukaryotic cytosol
Østergaard, H., Tachibana, C. & Winther, Jakob R., 2004, In: Journal of Cell Biology. 166, 3, p. 337-345 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Saccharopepsin
Winther, Jakob R., Phylip, L. H. & Kay, J., 2004, Aspartic and Metallo Peptidases. Barrett, A. J., Rawlings, N. D. & Woessner, J. F. (eds.). 2. ed. Elsevier, p. 87-90 4 p. (Handbook of Proteolytic Enzymes, Vol. 1).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
The Contributions of Protein Disulfide Isomerase and Its Homologues to Oxidative Protein Folding in the Yeast Endoplasmic Reticulum
Xiao, R., Wilkinson, B., Solovyov, A., Winther, Jakob R., Holmgren, A., Lundström-Ljung, J. & Gilbert, H. F., 2004, In: Journal of Biological Chemistry. 279, 48, p. 49780-49786 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 5143
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In Silico prediction of mutant HIV-1 proteases cleaving a target sequence
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A soluble, folded protein without charged amino acid residues
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Computational redesign of thioredoxin is hypersensitive towards minor conformational changes in the backbone template
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