Karsten Kristiansen

Karsten Kristiansen

Professor


  1. 2016
  2. Published

    Human gut microbes impact host serum metabolome and insulin sensitivity

    Pedersen, H. K., Gudmundsdottir, V., Nielsen, H. B., Hyotylainen, T., Nielsen, T., Jensen, B. A. H., Forslund, K., Hildebrand, F., Prifti, E., Falony, G., Le Chatelier, E., Levenez, F., Doré, J., Mattila, I., Plichta, D. R., Pöhö, P., Hellgren, L. I., Arumugam, M., Sunagawa, S., Vieira-Silva, S. & 14 others, Jørgensen, T., Holm, J. B., Trošt, K., Kristiansen, Karsten, Brix, Susanne, Raes, J., Wang, J., Hansen, Torben, Bork, P., Brunak, Søren, Oresic, M., Ehrlich, S. D., Pedersen, Oluf Borbye & MetaHIT Consortium, M. C., 2016, In: Nature. 535, 7612, p. 376-381 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    FFAR4 (GPR120) signaling is not required for anti-inflammatory and insulin-sensitizing effects of omega-3 fatty acids

    Pærregaard, S. I., Andersen, M. A., Serup, A. K. L., Ma, Tao, Kiens, Bente, Madsen, L., Kristiansen, Karsten & Jensen, Benjamin Anderschou Holbech, 2016, In: Mediators of Inflammation. 2016, 12 p., 1536047.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Importance of the fat content within the cheese-matrix for blood lipid profile, faecal fat excretion, and gut microbiome in growing pigs

    Thorning, T. K., Raben, Anne, Bendsen, N. T., Jørgensen, H. J. H., Kiilerich, P., Ardö, Ylva Margareta, Lorenzen, J. K., Kristiansen, Karsten & Astrup, A., 2016, In: International Dairy Journal. 61, p. 67-75 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    A reference gene catalogue of the pig gut microbiome

    Xiao, L., Estellé, J., Kiilerich, P., Ramayo-Caldas, Y., Xia, Z., Feng, Q., Liang, S., Pedersen, A. Ø., Kjeldsen, N. J., Liu, C., Maguin, E., Doré, J., Pons, N., Le Chatelier, E., Prifti, E., Li, J., Jia, H., Liu, X., Xu, X., Ehrlich, S. D. & 4 others, Madsen, L., Kristiansen, Karsten, Rogel-Gaillard, C. & Wang, J., 2016, In: Nature Microbiology. 1, 6 p., 16161.

    Research output: Contribution to journalLetterResearchpeer-review

  6. Published

    Shotgun metagenomics of 250 adult twins reveals genetic and environmental impacts on the gut microbiome

    Xie, H., Guo, R., Zhong, H., Feng, Q., Lan, Z., Qin, B., Ward, K. J., Jackson, M. A., Xia, Y., Chen, X., Chen, B., Xia, H., Xu, C., Li, F., Xu, X., Al-Aama, J. Y., Yang, H., Wang, J., Kristiansen, K., Wang, J. & 5 others, Steves, C. J., Bell, J. T., Li, J., Spector, T. D. & Jia, H., 2016, In: Cell Systems. 3, 6, p. 572-584.e3 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2015
  8. Published

    Global gene expression profiling of brown to white adipose tissue transformation in sheep reveals novel transcriptional components linked to adipose remodeling

    Basse, A. L., Dixen, K., Yadav, R., Tygesen, M. P., Qvortrup, Klaus, Kristiansen, Karsten, Quistorff, B., Gupta, R., Wang, J. & Hansen, Jacob B., 2015, In: BMC Genomics. 16, 19 p., 215.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios

    Besenbacher, S., Liu, S., Gonzalez-Izarzugaza, J. M., Grove, J., Belling, K. G., Bork-Jensen, J., Huang, S., Als, T. D., Li, S., Yadav, R., Rubio García, A., Lescai, F., Demontis, D., Rao, J., Ye, W., Mailund, T., Møllegaard Friborg, R., Pedersen, C. N. S., Xu, R., Sun, J. & 27 others, Liu, H., Wang, O., Cheng, X., Flores, D., Rydza, E. K., Rapacki, K., Sørensen, J. D., Chmura, P. J., Westergaard, David, Dworzynski, P., Sørensen, Thorkild I.A., Lund, O., Hansen, Torben, Xu, X., Li, N., Bolund, L., Pedersen, Oluf Borbye, Eiberg, Hans Rudolf Lytchoff, Krogh, Anders, Børglum, A. D., Brunak, Søren, Kristiansen, Karsten, Schierup, M. H., Wang, J., Gupta, R., Villesen, P. & Rasmussen, Simon, 2015, In: Nature Communications. 6, 9 p., 5969.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Dynamics and stabilization of the human gut microbiome during the first year of life

    Bäckhed, G. F., Roswall, J., Peng, Y., Feng, Q., Jia, H., Kovatcheva-Datchary, P., Li, Y., Xia, Y., Xie, H., Zhong, H., Khan, M. T., Zhang, J., Li, J., Xiao, L., Al-Aama, J., Zhang, D., Lee, Y. S., Kotowska, D. E., Colding, C. S., Tremaroli, V. & 7 others, Yin, Y., Bergman, S., Xu, X., Madsen, L., Kristiansen, Karsten, Dahlgren, J. & Wang, J., 2015, In: Cell Host & Microbe. 17, 5, p. 690-703 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    De novo assembly of a haplotype-resolved human genome

    Cao, H., Wu, H., Luo, R., Huang, S., Sun, Y., Tong, X., Xie, Y., Liu, B., Yang, H., Zheng, H., Li, J., Li, B., Wang, Y., Yang, F., Sun, P., Liu, S., Gao, P., Huang, H., Sun, J., Chen, D. & 21 others, He, G., Huang, W., Huang, Z., Li, Y., Tellier, L. C. A. M., Liu, X., Feng, Q., Xu, X., Zhang, X., Bolund, L., Krogh, Anders, Kristiansen, Karsten, Drmanac, R., Drmanac, S., Nielsen, R., Li, S., Wang, J., Yang, H., Li, Y., Wong, G. K. & Wang, J., 2015, In: Nature Biotechnology. 33, 6, p. 617-626 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Intake of hydrolyzed casein is associated with reduced dody fat accretion and enhanced phase II metabolism in obesity prone C57BL/6J mice

    Clausen, M. R., Zhang, X., Yde, C. C., Ditlev, D. B., Lillefosse, H. H., Madsen, L., Kristiansen, Karsten, Liaset, B. & Bertram, H. C., 2015, In: P L o S One. 10, 3, 18 p., e0118895.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Polyacetylenes from carrots (Daucus carota) improve glucose uptake in vitro in adipocytes and myotubes

    El-Houri, R. B., Kotowska, D. E., Christensen, K. B., Bhattacharya, S., Oksbjerg, N., Wolber, G., Kristiansen, Karsten & Christensen, L. P., 2015, In: Food & Function. 6, 7, p. 2135-2144 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Gut microbiome development along the colorectal adenoma-carcinoma sequence

    Feng, Q., Liang, S., Jia, H., Stadlmayr, A., Tang, L., Lan, Z., Zhang, D., Xia, H., Xu, X., Jie, Z., Su, L., Li, X., Li, X., Li, J., Xiao, L., Huber-Schönauer, U., Niederseer, D., Xu, X., Al-Aama, J. Y., Yang, H. & 6 others, Wang, J., Kristiansen, Karsten, Arumugam, Mani, Tilg, H., Datz, C. & Wang, J., 2015, In: Nature Communications. 6, 13 p., 6528.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Tissue inhibitor of matrix metalloproteinase-1 is required for high-fat diet-induced glucose intolerance and hepatic steatosis in mice

    Fjære, E., Andersen, C., Myrmel, L. S., Petersen, R. K., Hansen, J. B., Tastesen, H. S., Mandrup-Poulsen, Thomas, Brünner, N., Kristiansen, Karsten, Madsen, L. & Rømer, M. U. K., 2015, In: PloS one. 10, 7, 19 p., e0132910.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

    Forslund, K., Hildebrand, F., Nielsen, T., Falony, G., Le Chatelier, E., Sunagawa, S., Prifti, E., Vieira-Silva, S., Gudmundsdottir, V., Pedersen, H. K., Arumugam, M., Kristiansen, K., Yvonne Voigt, A., Vestergaard, H., Hercog, R., Igor Costea, P., Roat Kultima, J., Li, J., Jørgensen, T., Levenez, F. & 9 others, Dore, J., Nielsen, H. B., Brunak, Søren, Raes, J., Hansen, Torben, Wang, J., Dusko Ehrlich, S., Bork, P. & Pedersen, Oluf Borbye, 2015, In: Nature. 528, 7581, p. 262-266 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Transcriptome profiling of brown adipose tissue during cold exposure reveals extensive regulation of glucose metabolism

    Hao, Q., Yadav, R., Basse, A. L., Petersen, S., Sonne, Si Brask, Rasmussen, Simon, Zhu, Q., Lu, Z., Wang, J., Audouze, K., Gupta, R., Madsen, L., Kristiansen, Karsten & Hansen, Jacob B., 2015, In: American Journal of Physiology: Endocrinology and Metabolism. 308, 5, p. E380-E392 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Aniline is rapidly converted into Paracetamol impairing male reproductive development

    Holm, J. B., Chalmey, C., Modick, H., Jensen, L. S., Dierkes, G., Weiss, T., Jensen, Benjamin Anderschou Holbech, Nørregard, M. M., Borkowski, K., Styrishave, Bjarne, Koch, H. M., Mazaud-Guittot, S., Jegou, B., Kristiansen, Karsten & Kristensen, D. M., 2015, In: Toxicological Sciences. 148, 1, p. 288-298 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Chronic Trichuris muris infection decreases diversity of the intestinal microbiota and concomitantly increases the abundance of lactobacilli

    Holm, J. B., Sorobetea, D., Kiilerich, P., Ramayo-Caldas, Y., Estellé, J., Ma, Tao, Madsen, L., Kristiansen, Karsten & Svensson-Frej, M., 2015, In: PLOS ONE. 10, 5, 22 p., e0125495.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Dietary n-6 PUFA, carbohydrate: protein ratio and change in body weight and waist circumference: a follow-up study

    Jakobsen, M. U., Madsen, L., Dethlefsen, C., Due, K. M., Halkjaer, J., Sørensen, Thorkild I.A., Kristiansen, Karsten & Overvad, K., 2015, In: Public Health Nutrition. 18, 07, p. 1317-1323 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    In vitro screening of inhibition of PPAR-γ activity as a first step in identification of potential breast carcinogens

    Kopp, T. I., Lundqvist, J., Petersen, R. K., Oskarsson, A., Kristiansen, Karsten, Nellemann, C. & Vogel, U., 2015, In: Human & Experimental Toxicology. 34, 11, p. 1106-1118 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Intake of farmed Atlantic salmon fed soybean oil increases hepatic levels of arachidonic acid-derived oxylipins and ceramides in mice

    Midtbø, L. K., Borkowska, A. G., Bernhard, A., Rønnevik, A. K., Lock, E., Fitzgerald, M. L., Torstensen, B. E., Liaset, B., Brattelid, T., Pedersen, T. L., Newman, J. W., Kristiansen, Karsten & Madsen, L., 2015, In: Journal of Nutritional Biochemistry. 26, 6, p. 585-595 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Medium chain fatty acids from milk induce angiopoietin-like 4 (ANGPTL4) gene expression

    Nielsen, S. D., Amer, B., Young, J. F., Mortensen, G., Petersen, R. K., Kristiansen, Karsten & Dalsgaard, T. K., 2015, In: International Dairy Journal. 42, p. 34-41 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Full-length single-cell RNA-seq applied to a viral human cancer: applications to HPV expression and splicing analysis in HeLa S3 cells

    Wu, L., Zhang, X., Zhao, Z., Wang, L., Li, B., Li, G., Dean, M., Yu, Q., Wang, Y., Lin, X., Rao, W., Mei, Z., Li, Y., Jiang, R., Yang, H., Li, F., Xie, G., Xu, L., Wu, K., Zhang, J. & 9 others, Chen, J., Wang, T., Kristiansen, Karsten, Zhang, X., Li, Y., Yang, H., Wang, J., Hou, Y. & Xu, X., 2015, In: GigaScience. 4, 17 p., 51.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    A catalog of the mouse gut metagenome: [incl. Author Correction]

    Xiao, L., Feng, Q., Liang, S., Sonne, S. B., Xia, Z., Qiu, X., Li, X., Long, H., Zhang, J., Zhang, D., Liu, C., Fang, Z., Chou, J., Glanville, J., Hao, Q., Kotowska, D. E., Colding, C. S., Licht, T. R., Wu, D., Yu, J. & 17 others, Sung, J. J. Y., Liang, Q., Li, J., Jia, H., Lan, Z., Tremaroli, V., Dworzynski, P., Nielsen, H. B., Bäckhed, G. F., Dore, J., Le Chatelier, E., Ehrlich, S. D., Lin, J. C., Arumugam, Mani, Wang, J., Madsen, L. & Kristiansen, Karsten, 2015, In: Nature Biotechnology. 33, 10, p. 1103-1108 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    MicroRNA-455 regulates brown adipogenesis via a novel HIF1an-AMPK-PGC1α signaling network

    Zhang, H., Guan, M., Townsend, K. L., Huang, T. L., An, D., Yan, X., Xue, R., Schulz, T. J., Winnay, J., Mori, M., Hirshman, M. F., Kristiansen, Karsten, Tsang, J. S., White, A. P., Cypess, A. M., Goodyear, L. J. & Tseng, Y., 2015, In: E M B O Reports. 16, 10, p. 1378-1393 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    The oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment

    Zhang, X., Zhang, D., Jia, H., Feng, Q., Wang, D., Liang, D., Wu, X., Li, J., Tang, L., Li, Y., Lan, Z., Chen, B., Li, Y., Zhong, H., Xie, H., Jie, Z., Chen, W., Tang, S., Xu, X., Wang, X. & 28 others, Cai, X., Liu, S., Xia, Y., Li, J., Qiao, X., Al-Aama, J. Y., Chen, H., Wang, L., Wu, Q., Zhang, F., Zheng, W., Li, Y., Zhang, M., Luo, G., Xue, W., Xiao, L., Li, J., Chen, W., Xu, X., Yin, Y., Yang, H., Wang, J., Kristiansen, Karsten, Liu, L., Li, T., Huang, Q., Li, Y. & Wang, J., 2015, In: Nature Medicine. 21, 8, p. 895-905 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2014
  29. Published

    2-(2-Bromophenyl)-formononetin and 2-heptyl-formononetin are PPARγ partial agonists and reduce lipid accumulation in 3T3-L1 adipocytes

    Andersen, C., Kotowska, D. E., Tortzen, C., Kristiansen, Karsten, Nielsen, J. & Petersen, R. K., 2014, In: Bioorganic and Medicinal Chemistry. 22, 21, p. 6105-6111 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Identification of odorant-receptor interactions by global mapping of the human odorome

    Audouze, K. M. L., Tromelin, A., Le Bon, A. M., Belloir, C., Petersen, R. K., Kristiansen, Karsten, Brunak, Søren & Taboureau, O., 2014, In: PLOS ONE. 9, 4, p. e93037 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Proteomic analysis of cAMP-mediated signaling during differentiation of 3 T3-L1 preadipocytes

    Borkowski, K., Wrzesinski, K., Rogowska-Wrzesinska, A., Audouze, K. M. L., Bakke, J., Petersen, R. K., Haj, F. G., Madsen, L. & Kristiansen, Karsten, 2014, In: B B A - Proteins and Proteomics. 1844, 12, p. 2096-2107 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Weight cycling promotes fat gain and altered clock gene expression in adipose tissue in C57BL/6J mice

    Dankel, S. N., Degerud, E. M., Borkowski, K., Fjære, E., Midtbø, L. K., Haugen, C., Solsvik, M. H., Lavigne, A. M., Liaset, B., Sagen, J. V., Kristiansen, Karsten, Mellgren, G. & Madsen, L., 2014, In: American Journal of Physiology: Endocrinology and Metabolism. 306, 2, p. E210-E224 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Screening for bioactive metabolites in plant extracts modulating glucose uptake and fat accumulation

    El-Houri, R. B., Kotowska, D. E., Olsen, L. C. B., Bhattacharya, S., Christensen, L. P., Grevsen, K., Oksbjerg, N., Færgeman, N. J., Kristiansen, Karsten & Christensen, K. B., 2014, In: Evidence - Based Complementary and Alternative Medicine. 2014, 8 p., 156398.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Indomethacin treatment prevents high fat diet-induced obesity and insulin resistance but not glucose intolerance in C57BL/6J Mice

    Fjære, E., Aune, U. L., Røen, K., Keenan, A. H., Ma, Tao, Borkowski, K., Kristensen, D. M. B., Novotny, G. W., Mandrup-Poulsen, Thomas, Hudson, B. D., Milligan, G., Xi, Y., Newman, J. W., Haj, F. G., Liaset, B., Kristiansen, Karsten & Madsen, L., 2014, In: The Journal of Biological Chemistry. 289, 23, p. 16032-16045 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    PPARγ ligand production is tightly linked to clonal expansion during initiation of adipocyte differentiation

    Hallenborg, P., Petersen, R. K., Feddersen, S., Sundekilde, U. K., Hansen, Jacob B., Blagoev, B., Madsen, L. & Kristiansen, Karsten, 2014, In: Journal of Lipid Research. 55, 12, p. 2491-2500 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    The sheep genome illuminates biology of the rumen and lipid metabolism

    Jiang, Y., Xie, M., Chen, W., Talbot, R., Maddox, J. F., Faraut, T., Wu, C., Muzny, D. M., Li, Y., Zhang, W., Stanton, J-A., Brauning, R., Barris, W. C., Hourlier, T., Aken, B. L., Searle, S. M. J., Adelson, D. L., Bian, C., Cam, G. R., Chen, Y. & 53 others, Cheng, S., DeSilva, U., Dixen, K., Dong, Y., Fan, G., Franklin, I. R., Fu, S., Fuentes-Utrilla, P., Guan, R., Highland, M. A., Holder, M. E., Huang, G., Ingham, A. B., Jhangiani, S. N., Kalra, D., Kovar, C. L., Lee, S. L., Liu, W., Liu, X., Lu, C., Lv, T., Mathew, T., McWilliam, S., Menzies, M., Pan, S., Robelin, D., Servin, B., Townley, D., Wang, W., Wei, B., White, S. N., Yang, X., Ye, C., Yue, Y., Zeng, P., Zhou, Q., Hansen, Jacob B., Kristiansen, Karsten, Gibbs, R. A., Flicek, P., Warkup, C. C., Jones, H. E., Oddy, V. H., Nicholas, F. W., McEwan, J. C., Kijas, J. W., Wang, J., Worley, K. C., Archibald, A. L., Cockett, N., Xu, X., Wang, W. & Dalrymple, B. P., 2014, In: Science. 344, 6188, p. 1168-1173 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Isomeric C-12-Alkamides from the roots of Echinacea purpurea improve basal and insulin-dependent glucose uptake in 3T3-L1 adipocytes

    Kotowska, D. E., El-Houri, R. B., Borkowski, K., Petersen, R. K., Fretté, X., Wolber, G., Grevsen, K., Christensen, K. B., Christensen, L. P. & Kristiansen, Karsten, 2014, In: Planta Medica. 80, 18, p. 1712-1720 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    An integrated catalog of reference genes in the human gut microbiome

    Li, J., Jia, H., Cai, X., Zhong, H., Feng, Q., Sunagawa, S., Arumugam, M., Kultima, J. R., Prifti, E., Nielsen, T., Juncker, A., Manichanh, C., Chen, B., Zhang, W., Levenez, F., Wang, J., Xu, X., Xiao, L., Liang, S., Zhang, D. & 17 others, Zhang, Z., Chen, W., Zhao, H., Al-Aama, J. Y., Edris, S., Yang, H., Wang, J., Hansen, Torben, Nielsen, H. B., Brunak, S., Kristiansen, Karsten, Guarner, F., Pedersen, Oluf Borbye, Doré, J., Ehrlich, S. D., Bork, P. & Wang, J., 2014, In: Nature Biotechnology. 32, 8, p. 834-845 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Variation and association to diabetes in 2000 full mtDNA sequences mined from an exome study in a Danish population

    Li, S., Besenbacher, S., Li, Y., Kristiansen, Karsten, Grarup, Niels, Albrechtsen, Anders, Sparsø, T. H., Korneliussen, Thorfinn Sand, Hansen, Torben, Wang, J., Nielsen, Rasmus, Pedersen, Oluf Borbye, Bolund, L. & Schierup, M. H., 2014, In: European Journal of Human Genetics. 22, p. 1040-1045 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Urinary loss of tricarboxylic acid cycle intermediates as revealed by metabolomics studies: an underlying mechanism to reduce lipid accretion by whey protein ingestion?

    Lillefosse, H. H., Clausen, M. R., Yde, C. C., Ditlev, D. B., Zhang, X., Du, Z., Bertram, H. C. S., Madsen, L., Kristiansen, Karsten & Liaset, B., 2014, In: Journal of Proteome Research. 13, 5, p. 2560-2570 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes

    Nielsen, H. B., Almeida, M., Juncker, A., Rasmussen, S., Li, J., Sunagawa, S., Plichta, D. R., Gautier, L., Pedersen, A. G., Le Chatelier, E., Pelletier, E., Bonde, I., Nielsen, T., Manichanh, C., Arumugam, M., Batto, J-M., dos Santos, M. B. Q., Blom, N., Borruel, N., Burgdorf, K. S. & 31 others, Boumezbeur, F., Casellas, F., Doré, J., Dworzynski, P., Guarner, F., Hansen, Torben, Hildebrand, F., Kaas, R. S., Kennedy, S., Kristiansen, Karsten, Kultima, J. R., Léonard, P., Levenez, F., Lund, O., Moumen, B., Le Paslier, D., Pons, N., Pedersen, Oluf Borbye, Prifti, E., Qin, J., Raes, J., Sørensen, Søren Johannes, Tap, J., Tims, S., Ussery, D., Yamada, T., Renault, P., Sicheritz-Pontén, T., Bork, P., Wang, J. & MetaHIT Consortium, M. C., 2014, In: Nature Biotechnology. 32, 8, p. 822–828 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Activation of the angiopoietin-like 4 (ANGPLT4) gene by milk fat and casein

    Nielsen, S. D., Young, J. F., Mortensen, G., Petersen, R. K., Kristiansen, Karsten & Dalsgaard, T. K., 2014, In: International Dairy Journal. 36, 2, p. 136-142 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Molecular aspects of adipoepithelial transdifferentiation in mouse mammary gland

    Prokesch, A., Smorlesi, A., Perugini, J., Manieri, M., Ciarmela, P., Mondini, E., Trajanoski, Z., Kristiansen, Karsten, Giordano, A., Bogner-Strauss, J. G. & Cinti, S., 2014, In: Stem Cells. 32, 10, p. 2756-2766 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    A Mixture of cod and scallop protein reduces adiposity and improves glucose tolerance in high-fat fed male C57BL/6J mice

    Tastesen, H. S., Rønnevik, A. K., Borkowski, K., Madsen, L., Kristiansen, Karsten & Liaset, B., 2014, In: P L o S One. 9, 11, 12 p., e112859.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Scallop protein with endogenous high taurine and glycine content prevents high-fat, high-sucrose-induced obesity and improves plasma lipid profile in male C57BL/6J mice

    Tastesen, H. S., Keenan, A. H., Madsen, L., Kristiansen, Karsten & Liaset, B., 2014, In: Amino Acids. 46, 7, p. 1659-1671 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Multi-block PCA and multi-compartmental study of the metabolic responses to intake of hydrolysed versus intact casein in C57BL/6J mice by NMR-based metabolomics

    Yde, C. C., Clausen, M. R., Ditlev, D. B., Lillefosse, H., Madsen, L., Kristiansen, Karsten, Liaset, B. & Bertram, H. C. S., 2014, In: Metabolomics. 10, 5, p. 938-949 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. 2013
  48. Published

    Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes

    Albrechtsen, A., Grarup, N., Li, Y., Sparsø, T. H., Tian, G., Cao, H., Jiang, T., Kim, S. Y., Korneliussen, T. S., Li, Q., Nie, C., Wu, R., Skotte, L., Morris, A. P., Ladenvall, C., Cauchi, S., Stancáková, A., Andersen, G., Astrup, A., Banasik, K. & 86 others, Bennett, A. J., Bolund, L., Charpentier, G., Chen, Y., Dekker, J. M., Doney, A. S. F., Dorkhan, M., Forsen, T., Frayling, T. M., Groves, C. J., Gui, Y., Hallmans, G., Hattersley, A. T., He, K., Hitman, G. A., Holmkvist, J., Huang, S., Jiang, H., Jin, X., Justesen, Johanne Marie, Kristiansen, Karsten, Kuusisto, J., Lajer, M., Lantieri, O., Li, W., Liang, H., Liao, Q., Liu, X., Ma, T., Ma, X., Manijak, M. P., Marre, M., Mokrosinski, J., Morris, A. D., Mu, B., Nielsen, A. A., Nijpels, G., Nilsson, P., Palmer, C. N. A., Rayner, N. W., Renström, F., Ribel-Madsen, R., Robertson, N., Rolandsson, O., Rossing, P., Schwartz, Thue W., Slagboom, P. E., Sterner, M., Tang, M., Tarnow, L., Tuomi, T., Van't Riet, E., van Leeuwen, N., V Varga, Tibor, Vestmar, M. A., Walker, M., Wang, B., Wang, Y., Wu, H., Xi, F., Yengo, L., Yu, C., Zhang, X., Zhang, J., Zhang, Q., Zhang, W., Zheng, H., Zhou, Y., Altshuler, D., 't Hart, L. M., Franks, P. W., Balkau, B., Froguel, P., McCarthy, M. I., Laakso, M., Groop, L., Christensen, C., Brandslund, I., Lauritzen, T., Witte, D. R., Linneberg, A., Jørgensen, T., Hansen, Torben, Wang, J., Nielsen, Rasmus & Pedersen, Oluf Borbye, 2013, In: Diabetologia. 56, 2, p. 298-310 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    2-heptyl-formononetin increases cholesterol and induces hepatic steatosis in mice

    Andersen, C., Schjoldager, J. G., Tortzen, C., Vegge, A., Hufeldt, M. R., Skaanild, M. T., Vogensen, Finn Kvist, Kristiansen, Karsten, Hansen, Axel Kornerup & Nielsen, J., 2013, In: Journal of Biomedicine and Biotechnology. 2013, 13 p., 926942.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Bioactive components from flowers of Sambucus nigra L. increase glucose uptake in primary porcine myotube cultures and reduce fat accumulation in Caenorhabditis elegans

    Bhattacharya, S., Christensen, K. B., Olsen, L. C. B., Christensen, L. P., Grevsen, K., Færgeman, N. J., Kristiansen, Karsten, Young, J. F. & Oksbjerg, N., 2013, In: Journal of Agricultural and Food Chemistry. 61, 46, p. 11033-11040 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    A short-read multiplex sequencing method for reliable, cost-effective and high-throughput genotyping in large-scale studies: [plus] Erratum

    Cao, H., Wang, Y., Zhang, W., Chai, X., Zhang, X., Chen, S., Yang, F., Zhang, C., Guo, Y., Liu, Y., Tang, Z., Chen, C., Xue, Y., Zhen, H., Xu, Y., Rao, B., Liu, T., Zhao, M., Zhang, W., Li, Y. & 6 others, Zhang, X., Tellier, L. C. A. M., Krogh, Anders, Kristiansen, Karsten, Wang, J. & Li, J., 2013, In: Human Mutation. 34, 12, p. 1715-1720 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Dietary eicosapentaenoic acid supplementation accentuates hepatic triglyceride accumulation in mice with impaired fatty acid oxidation capacity

    Du, Z., Ma, Tao, Liaset, B., Keenan, A. H., Araujo, P., Lock, E., Demizieux, L., Degrace, P., Frøyland, L., Kristiansen, Karsten & Madsen, L., 2013, In: B B A - Molecular and Cell Biology of Lipids. 1831, 2, p. 291-299 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets

    Grarup, N., Sulem, P., Sandholt, C. H., Thorleifsson, G., Ahluwalia, T. V. S., Steinthorsdottir, V., Bjarnason, H., Gudbjartsson, D. F., Magnusson, O. T., Sparsø, T., Albrechtsen, A., Kong, A., Masson, G., Tian, G., Cao, H., Nie, C., Kristiansen, K., Husemoen, L. L., Thuesen, B., Li, Y. & 10 others, Nielsen, Rasmus, Linneberg, Allan René, Olafsson, I., Eyjolfsson, G. I., Jørgensen, T., Wang, J., Hansen, Torben, Thorsteinsdottir, U., Stefánsson, K. & Pedersen, Oluf Borbye, 2013, In: P L o S Genetics. 9, 6, 12 p., e1003530.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Discovery of a novel selective PPARγ ligand with partial agonist binding properties by integrated in Silico/in Vitro work flow

    Kouskoumvekaki, I., Petersen, R. K., Fratev, F. F., Taboureau, O., Nielsen, T. E., Oprea, T., Sonne, Si Brask, Flindt, E. N., Jonsdottir, S. O. & Kristiansen, Karsten, 2013, In: Journal of Chemical Information and Modeling. 53, 4, p. 923-937 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Richness of human gut microbiome correlates with metabolic markers

    Le Chatelier, E., Nielsen, T., Qin, J., Prifti, E., Hildebrand, F., Falony, G., Almeida, M., Arumugam, M., Batto, J-M., Kennedy, S., Leonard, P., Li, J., Burgdorf, K. S., Grarup, N., Jørgensen, T., Brandslund, I., Nielsen, H. B., Juncker, A., dos Santos, M. B. Q., Levenez, F. & 62 others, Pons, N., Rasmussen, Simon, Sunagawa, S., Tap, J., Tims, S., Zoetendal, E. G., Brunak, S., Clément, K., Doré, J., Kleerebezem, M., Kristiansen, Karsten, Renault, P., Sicheritz-Ponten, T., de Vos, W. M., Zucker, J., Raes, J., Hansen, Torben, Bork, P., Wang, J., Ehrlich, S. D., Pedersen, Oluf Borbye, Guedon, E., Delorme, C., Layec, S., Khaci, G., van de Guchte, M., Vandemeulebrouck, G., Jamet, A., Dervyn, R., Sanchez, N., Maguin, E., Haimet, F., Winogradski, Y., Cultrone, A., Leclerc, M., Juste, C., Blottière, H., Pelletier, E., LePaslier, D., Artiguenave, F., Bruls, T., Weissenbach, J., Turner, K., Parkhill, J., Antolin, M., Manichanh, C., Casellas, F., Boruel, N., Varela, E., Torrejon, A., Guarner, F., Denariaz, G., Derrien, M., van Hylckama Vlieg, J. E. T., Veiga, P., Oozeer, R., Knol, J., Rescigno, M., Brechot, C., Mérieux, A., M'Rini, C. & Yamada, T., 2013, In: Nature. 500, 7464, p. 541-546 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Hydrolyzed Casein Reduces Diet-Induced Obesity in Male C57BL/6J Mice

    Lillefosse, H. H., Tastesen, H. S., Du, Z., Ditlev, D. B., Thorsen, F. A., Madsen, L., Kristiansen, Karsten & Liaset, B., 2013, In: The Journal of Nutrition. 143, 9, p. 1367-1375 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes

    Lohmueller, K. E., Sparsø, T. H., Li, Q., Galijatovic, E. A. A., Korneliussen, T. S., Albrechtsen, A., Banasik, K., Grarup, N., Hallgrimsdottir, I., Kiil, K., Oskari Kilpeläinen, T., Krarup, N. T., Pers, T. H., Sanchez, G., Hu, Y., DeGiorgio, M., Jørgensen, T., Sandbæk, A., Lauritzen, T., Brunak, S. & 6 others, Kristiansen, Karsten, Li, Y., Hansen, Torben, Wang, J., Nielsen, Rasmus & Pedersen, Oluf Borbye, 5 Dec 2013, In: American Journal of Human Genetics. 93, 6, p. 1072-1086 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Intake of farmed Atlantic salmon fed soybean oil increases insulin resistance and hepatic lipid accumulation in mice

    Midtbø, L. K., Ibrahim, M. M., Myrmel, L. S., Aune, U. L., Alvheim, A. R., Liland, N. S., Torstensen, B. E., Rosenlund, G., Liaset, B., Brattelid, T., Kristiansen, Karsten & Madsen, L., 2013, In: P L o S One. 8, 1, 11 p., e53094.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Mælk der slanker? Mælk som regulator af lipidmetabolisme og overvægt. Afdækning af mælks evne til at øge faste-induceret adipose faktor (FIAF)-aktivitet

    Nielsen, S. D., Dalsgaard, T. K., Mortensen, G., Lorenzen, J. K., Astrup, A., Kristiansen, Karsten & Madsen, L., 2013, In: Maelkeritidende. 2, p. 8-9 2 p.

    Research output: Contribution to journalJournal articleCommunication

  60. Published

    Profiling of lipid species by normal-phase liquid chromatography, nanoelectrospray ionization, and ion trap-orbitrap mass spectrometry

    Sokol, E., Almeida, R., Hannibal-Bach, H. K., Kotowska, D. E., Vogt, J., Baumgart, J., Kristiansen, Karsten, Nitsch, R., Knudsen, J. & Ejsing, C. S., 2013, In: Analytical Biochemistry. 443, 1, p. 88-96 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration

    Veland, I. R., Montjean, R., Eley, L., Pedersen, Lotte Bang, Schwab, A., Goodship, J., Kristiansen, Karsten, Pedersen, Stine Helene Falsig, Saunier, S. & Christensen, Søren Tvorup, 2013, In: P L o S One. 8, 4, 15 p., e60193.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Discovery of new PPARγ agonists based on arylopeptoids

    Worm-Leonhard, K., Hjelmgaard, T., Petersen, R. K., Kristiansen, Karsten & Nielsen, J., 2013, In: Bioorganic & Medicinal Chemistry Letters. 23, p. 4162-4165 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Ursolic acid induces cell death and modulates autophagy through JNK pathway in apoptosis-resistant colorectal cancer cells

    Xavier, C. P. R., Lima, C. F., Pedro, D. F. N., Wilson, J. M., Kristiansen, Karsten & Pereira-Wilson, C., 2013, In: Journal of Nutritional Biochemistry. 24, 4, p. 706-712 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. 2012
  65. Published

    Dietary linoleic acid elevates endogenous 2-AG and anandamide and induces obesity

    Alvheim, A. R., Malde, M. K., Osei-Hyiaman, D., Lin, Y. H., Pawlosky, R. J., Madsen, L., Kristiansen, Karsten, Frøyland, L. & Hibbeln, J. R., 2012, In: Obesity. 20, 10, p. 1984-1994 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Transcriptome and network changes in climbers at extreme altitudes

    Chen, F., Zhang, W., Liang, Y., Huang, J., Li, K., Green, C. D., Liu, J., Zhang, G., Zhou, B., Yi, X., Wang, W., Liu, H., Xu, X., Shen, F., Qu, N., Wang, Y., Gao, G., San, A., JiangBai, L., Sang, H. & 6 others, Fang, X., Kristiansen, Karsten, Yang, H., Wang, J., Han, J. J. & Wang, J., 2012, In: P L o S One. 7, 2, p. e31645-e31645

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma

    Guo, G., Gui, Y., Gao, S., Tang, A., Hu, X., Huang, Y., Jia, W., Li, Z., He, M., Sun, L., Song, P., Sun, X., Zhao, X., Yang, S., Liang, C., Wan, S., Zhou, F., Chen, C., Zhu, J., Li, X. & 35 others, Jian, M., Zhou, L., Ye, R., Huang, P., Chen, J., Jiang, T., Liu, X., Wang, Y., Zou, J., Jiang, Z., Wu, R., Wu, S., Fan, F., Zhang, Z., Liu, L., Yang, R., Liu, X., Wu, H., Yin, W., Zhao, X., Liu, Y., Peng, H., Jiang, B., Feng, Q., Li, C., Xie, J., Lu, J., Kristiansen, Karsten, Li, Y., Zhang, X., Li, S., Wang, J., Yang, H., Cai, Z. & Wang, J., 2012, In: Nature Genetics. 44, 1, p. 17-19 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Mdm2 controls CREB-dependent transactivation and initiation of adipocyte differentiation

    Hallenborg, P., Feddersen, S., Francoz, S., Murano, I., Sundekilde, U., Petersen, R. K., Akimov, V., Olson, M. V., Lozano, G., Cinti, S., Gjertsen, B. T., Madsen, L., Marine, J., Blagoev, B. & Kristiansen, Karsten, 2012, In: Cell Death and Differentiation. 19, 8, p. 1381-1389 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    High-glycemic index carbohydrates abrogate the antiobesity effect of fish oil in mice

    Hao, Q., Lillefosse, H. H., Fjære, E., Myrmel, L. S., Midtbø, L. K., Jarlsby, R. H., Ma, T., Jia, B., Petersen, R. K., Sonne, Si Brask, Chwalibog, André, Frøyland, L., Liaset, B., Kristiansen, Karsten & Madsen, L., 2012, In: American Journal of Physiology: Endocrinology and Metabolism. 302, 9, p. E1097-E1112 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    A comparative analysis of the intestinal metagenomes present in guinea pigs (Cavia porcellus) and humans (Homo sapiens)

    Hildebrand, F., Ebersbach, T., Nielsen, H. B., Li, X., Sonne, Si Brask, dos Santos, M. B. Q., Dimitrov, P., Madsen, L., Qin, J., Wang, J., Raes, J., Kristiansen, Karsten & Licht, T. R., 2012, In: B M C Genomics. 13, 514, 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm

    Hou, Y., Song, L., Zhu, P., Zhang, B., Tao, Y., Xu, X., Li, F., Wu, K., Liang, J., Shao, D., Wu, H., Ye, X., Ye, C., Wu, R., Jian, M., Chen, Y., Xie, W., Zhang, R., Chen, L., Liu, X. & 20 others, Yao, X., Zheng, H., Yu, C., Li, Q., Gong, Z., Mao, M., Yang, X., Yang, L., Li, J., Wang, W., Lu, Z., Gu, N., Laurie, G., Bolund, L., Kristiansen, Karsten, Wang, J., Yang, H., Li, Y., Zhang, X. & Wang, J., 2012, In: Cell. 148, 5, p. 873-885 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Activation of protein kinase A and exchange protein directly activated by cAMP promotes adipocyte differentiation of human mesenchymal stem cells

    Jia, B., Madsen, L., Petersen, R. K., Techer, N., Kopperud, R., Ma, T., Døskeland, S. O., Ailhaud, G., Wang, J., Amri, E. & Kristiansen, Karsten, 2012, In: P L o S One. 7, 3, 11 p., 0034114.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Single-cell sequencing analysis characterizes common and cell-lineage-specific mutations in a muscle-invasive bladder cancer

    Li, Y., Xu, X., Song, L., Hou, Y., Li, Z., Tsang, S., Li, F., Im, K., Wu, K., Wu, H., Ye, X., Li, G., Wang, L., Zhang, B., Liang, J., Xie, W., Wu, R., Jiang, H., Liu, X., Yu, C. & 20 others, Zheng, H., Jian, M., Nie, L., Wan, L., Shi, M., Sun, X., Tang, A., Guo, G., Gui, Y., Cai, Z., Li, J., Wang, W., Lu, Z., Zhang, X., Bolund, L., Kristiansen, Karsten, Wang, J., Yang, H., Dean, M. & Wang, J., 2012, In: GigaScience. 1, 12, 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Of mice and men: factors abrogating the antiobesity effect of omega-3 fatty acids

    Madsen, L. & Kristiansen, Karsten, 2012, In: Adipocytes. 1, 3, p. 173-176 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    PPARgamma-PGC-1alpha activity is determinant of alcohol related breast cancer

    Petersen, R. K., Larsen, Signe Liv Benzon, Jensen, D. M., Christensen, J., Olsen, A., Loft, Steffen, Nellemann, C. L., Overvad, K., Kristiansen, Karsten, Tjønneland, A. & Vogel, U., 2012, In: Cancer Letters. 315, 1, p. 59-68 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    A metagenome-wide association study of gut microbiota in type 2 diabetes

    Qin, J., Li, Y., Cai, Z., Li, S., Zhu, J., Zhang, F., Liang, S., Zhang, W., Guan, Y., Shen, D., Peng, Y., Zhang, D., Jie, Z., Wu, W., Qin, Y., Xue, W., Li, J., Han, L., Lu, D., Wu, P. & 36 others, Dai, Y., Sun, X., Li, Z., Tang, A., Zhong, S., Li, X., Chen, W., Xu, R., Wang, M., Feng, Q., Gong, M., Yu, J., Zhang, Y., Zhang, M., Hansen, Torben, Sanchez, G., Raes, J., Falony, G., Okuda, S., Almeida, M., LeChatelier, E., Renault, P., Pons, N., Batto, J., Zhang, Z., Chen, H., Yang, R., Zheng, W., Li, S., Yang, H., Wang, J., Ehrlich, S. D., Nielsen, R., Pedersen, Oluf Borbye, Kristiansen, Karsten & Wang, J., 2012, In: Nature. 490, 7418, p. 55-60 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Plant extracts of winter savory, purple coneflower, buckwheat and black elder activate PPAR-γ in COS-1 cells but do not lower blood glucose in Db/db Mice In vivo

    Schrader, E., Wein, S., Kristiansen, Karsten, Christensen, L. P., Rimbach, G. & Wolffram, S., 2012, In: Plant Foods for Human Nutrition. 67, 4, p. 377-383 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Mammalian tissues defective in nonsense-mediated mRNA decay display highly aberrant splicing patterns

    Weischenfeldt, Joachim Lütken, Waage, J. E., Tian, G., Zhao, J., Damgaard, I., Jakobsen, J. S., Kristiansen, Karsten, Krogh, Anders, Wang, J. & Porse, Bo Torben, 2012, In: Genome Biology (Online Edition). 13, 5, 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Resequencing 50 accessions of cultivated and wild rice yields markers for identifying agronomically important genes

    Xu, X., Liu, X., Ge, S., Jensen, J. D., Hu, F., Li, X., Dong, Y., Gutenkunst, R. N., Fang, L., Huang, L., Li, J., He, W., Zhang, G., Zheng, X., Zhang, F., Li, Y., Yu, C., Kristiansen, K., Zhang, X., Wang, J. & 5 others, Wright, M., McCouch, S., Nielsen, Rasmus, Wang, J. & Wang, W., 2012, In: Nature Biotechnology. 30, 1, p. 105-111 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor: Cell

    Xu, X., Hou, Y., Yin, X., Bao, L., Tang, A., Song, L., Li, F., Tsang, S., Wu, K., Wu, H., He, W., Zeng, L., Xing, M., Wu, R., Jiang, H., Liu, X., Cao, D., Guo, G., Hu, X., Gui, Y. & 19 others, Li, Z., Xie, W., Sun, X., Shi, M., Cai, Z., Wang, B., Zhong, M., Li, J., Lu, Z., Gu, N., Zhang, X., Goodman, L., Bolund, L., Wang, J., Yang, H., Kristiansen, Karsten, Dean, M., Li, Y. & Wang, J., 2012, In: Cell. 148, 5, p. 886-895 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. 2011
  82. Published

    Enterotypes of the human gut microbiome: [Plus]Corrigendum [Plus]Addendum

    Arumugam, M., Raes, J., Pelletier, E., Le Paslier, D., Yamada, T., Mende, D. R., Fernandes, G. R., Tap, J., Bruls, T., Batto, J-M., dos Santos, M. B. Q., Borruel, N., Casellas, F., Fernandez, L., Gautier, L., Hansen, T., Hattori, M., Hayashi, T., Kleerebezem, M., Kurokawa, K. & 31 others, Leclerc, M., Levenez, F., Manichanh, C., Nielsen, H. B., Nielsen, T., Pons, N., Poulain, J., Qin, J., Sicheritz-Ponten, T., Tims, S., Torrents, D., Ugarte, E., Zoetendal, E. G., Wang, J., Guarner, F., Pedersen, Oluf Borbye, de Vos, W. M., Brunak, Søren, Doré, J., Antolín, M., Artiguenave, F., Blottiere, H. M., Almeida, M., Brechot, C., Cara, C., Chervaux, C., Cultrone, A., Delorme, C., Denariaz, G., Kristiansen, Karsten & MetaHIT Consortium, M. C., 2011, In: Nature. 473, 7346, p. 174-180 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Insulin/IGF-I regulation of necdin and brown adipocyte differentiation via CREB- and FoxO1-associated pathways

    Cypess, A. M., Zhang, H., Schulz, T. J., Huang, T. L., Espinoza, D. O., Kristiansen, Karsten, Unterman, T. G. & Tseng, Y., 2011, In: Endocrinology. 152, 10, p. 3680-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Depot-dependent effects of adipose tissue explants on co-cultured hepatocytes

    Du, Z., Ma, T., Lock, E., Hao, Q., Kristiansen, Karsten, Frøyland, L. & Madsen, L., 1 Jan 2011, In: P L o S One. 6, 6, 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder

    Gui, Y., Guo, G., Huang, Y., Hu, X., Tang, A., Gao, S., Wu, R., Chen, C., Li, X., Zhou, L., He, M., Li, Z., Sun, X., Jia, W., Chen, J., Yang, S., Zhou, F., Zhao, X., Wan, S., Ye, R. & 33 others, Liang, C., Liu, C., Huang, P., Liu, C., Jiang, H., Wang, Y., Zheng, H., Sun, L., Liu, X., Jiang, Z., Feng, D., Chen, X. J., Wu, S., Zou, J., Zhang, Z., Yang, R., Zhao, J., Xu, C., Yin, W., Guan, Z., Ye, J., Zhang, H., Li, J., Kristiansen, Karsten, Nickerson, M. L., Theodorescu, D., Li, Y., Zhang, X., Li, S., Wang, J., Yang, H., Wang, J. & Cai, Z., 2011, In: Nature Genetics. 43, 9, p. 875-8 4 p.

    Research output: Contribution to journalLetterResearchpeer-review

  86. Published

    Transcriptional regulatory program in wild-type and retinoblastoma gene-deficient mouse embryonic fibroblasts during adipocyte differentiation

    Hakim-Weber, R., Krogsdam, A., Jørgensen, C., Fischer, M., Prokesch, A., Bogner-Strauss, J. G., Bornstein, S. R., Hansen, Jacob B., Madsen, L., Kristiansen, Karsten, Trajanoski, Z. & Hackl, H., 2011, In: BMC Research Notes. 4, p. 1-13 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Corticosteroid regulation of Na+,K+-ATPase α1-isoform expression in Atlantic salmon gill during smolt development

    Kiilerich, P., Pedersen, S. H., Kristiansen, Karsten & Madsen, S. S., 2011, In: General and Comparative Endocrinology. 170, 2, p. 283-289 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Increased levels of PPARbeta/delta and cyclin D1 in flat dysplastic ACF and adenomas in Apc(Min/+) mice

    Knutsen, H. K., Olstørn, H. B., Paulsen, J. E., Husøy, T., Goverud, I. L., Løberg, E. M., Kristiansen, Karsten & Alexander, J., 2011, In: Anticancer Research. 25, 6B, p. 3781-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Structural variation in two human genomes mapped at single-nucleotide resolution by whole genome de novo assembly

    Li, Y., Zheng, H., Luo, R., Wu, H., Zhu, H., Li, R., Cao, H., Wu, B., Huang, S., Shao, H., Ma, H., Zhang, F., Feng, S., Zhang, W., Du, H., Tian, G., Li, J., Zhang, X., Li, S., Bolund, L. & 8 others, Kristiansen, Karsten, de Smith, A. J., Blakemore, A. I. F., Coin, L. J. M., Yang, H., Wang, J., Wang, J. & Wang, J., 2011, In: Nature Biotechnology. 29, 8, p. 723-730 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Nutritional regulation of bile acid metabolism is associated with improved pathological characteristics of the metabolic syndrome

    Liaset, B., Hao, Q., Jørgensen, H. J. H., Hallenborg, P., Du, Z., Ma, T., Marschall, H., Kruhøffer, M., Li, R., Li, Q., Yde, C. C., Criales, G., Bertram, H. C. S., Mellgren, G., Ofjord, E. S., Lock, E., Espe, M., Frøyland, L., Madsen, L. & Kristiansen, Karsten, 2011, In: The Journal of Biological Chemistry. 286, 32, p. 28382-95 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Sucrose counteracts the anti-inflammatory effect of fish oil in adipose tissue and increases obesity development in mice

    Ma, Tao, Liaset, B., Hao, Q., Petersen, R. K., Fjære, E., Ngo, H. T., Lillefosse, H. H., Jørgensen, Stine Ringholm, Sonne, Si Brask, Treebak, Jonas Thue, Pilegaard, Henriette, Frøyland, L., Kristiansen, Karsten & Madsen, L., 2011, In: P L o S One. 6, 6, 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Pharmacophore-driven identification of PPAR¿ agonists from natural sources

    Petersen, R. K., Christensen, K. B., Assimopoulou, A. N., Fretté, X., Papageorgiou, V. P., Kristiansen, Karsten & Kouskoumvekaki, I., 2011, In: Journal of Computer - Aided Molecular Design. 25, 2, p. 107-16 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    An Aboriginal Australian genome reveals separate human dispersals into Asia

    Rasmussen, M., Guo, X., Wang, Y., Lohmueller, K. E., Rasmussen, S., Albrechtsen, A., Skotte, L., Lindgreen, S., Metspalu, M., Jombart, T., Kivisild, T., Zhai, W., Eriksson, A., Manica, A., Orlando, L., De La Vega, F. M., Tridico, S., Metspalu, E., Nielsen, K., Avila Arcos, M. D. C. & 38 others, Moreno Mayar, J. Víctor, Muller, C., Dortch, J., Gilbert, M Thomas P, Lund, O., Wesolowska, A., Karmin, M., Weinert, L. A., Wang, B., Li, J., Tai, S., Xiao, F., Hanihara, T., van Driem, G., Jha, A. R., Ricaut, F., de Knijff, P., Migliano, A. B., Gallego Romero, I., Kristiansen, Karsten, Lambert, D. M., Brunak, Søren, Forster, P., Brinkmann, B., Nehlich, O., Bunce, M., Richards, M., Gupta, R., Bustamante, C. D., Krogh, Anders, Foley, R. A., Lahr, M. M., Balloux, F., Sicheritz-Pontén, T., Villems, R., Nielsen, Rasmus, Wang, J. & Willerslev, Eske, 2011, In: Science. 334, 6052, p. 94-98 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Fatty acid composition in organs.

    Sonne, Si Brask, Treebak, Jonas Thue, Pilegaard, Henriette, Fjare, E., Froyland, L., Kristiansen, Karsten, Hao, Q., Madsen, L., Petersen, R. K., Ngo, H. T., Lillefosse, H. H., Liaset, B., Ringholm, S. & Ma, Tao, 2011

    Research output: Other contributionResearch

  95. Published

    Fatty acid composition in red blood cells.

    Sonne, Si Brask, Treebak, Jonas Thue, Pilegaard, Henriette, Fjare, E., Froyland, L., Kristiansen, Karsten, Hao, Q., Madsen, L., Petersen, R. K., Ngo, H. T., Lillefosse, H. H., Liaset, B., Ringholm, S. & Ma, Tao, 2011

    Research output: Other contributionResearch

  96. Published

    Fatty acid composition in the diets.

    Sonne, Si Brask, Treebak, Jonas Thue, Pilegaard, Henriette, Fjare, E., Froyland, L., Kristiansen, Karsten, Hao, Q., Madsen, L., Petersen, R. K., Ngo, H. T., Lillefosse, H. H., Liaset, B., Ringholm, S. & Ma, Tao, 2011

    Research output: Other contributionResearch

  97. Published

    Macronutrient composition in the diets.

    Sonne, Si Brask, Treebak, Jonas Thue, Pilegaard, Henriette, Fjare, E., Froyland, L., Kristiansen, Karsten, Hao, Q., Madsen, L., Petersen, R. K., Ngo, H. T., Lillefosse, H. H., Liaset, B., Ringholm, S. & Ma, Tao, 2011

    Research output: Other contributionResearch

  98. Published

    A Sleeping Beauty DNA transposon-based genetic sensor for functional screening of vitamin D3 analogues

    Staunstrup, N. H., Sharma, N., Bak, R. O., Svensson, L., Petersen, T. K., Aarenstrup, L., Kristiansen, Karsten, Bolund, L. & Mikkelsen, J. G., 2011, In: B M C Biotechnology. 11, 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. 2010
  100. Published

    The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation

    Barbatelli, G., Murano, I., Madsen, L., Hao, Q., Jimenez, M., Kristiansen, Karsten, Giacobino, J. P., Matteis, R. D. & Cinti, S., 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 298, 6, p. E1244-E1253

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Identification of bioactive compounds from flowers of black elder (Sambucus nigra L.) that activate the human peroxisome proliferator-activated receptor (PPAR) gamma

    Christensen, K. B., Petersen, R. K., Kristiansen, Karsten & Christensen, L. P., 2010, In: Phytotherapy Research. 24, Suppl 2, p. 129-32

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. Published

    Structure-activity study of dihydrocinnamic acids and discovery of the potent FFA1 (GPR40) agonist TUG-469

    Ulven, Elisabeth Rexen, Due-Hansen, M. E., Urban, C., Merten, N., Pfleiderer, M., Karlsen, K. K., Rasmussen, S. S., Steensgaard, M., Hamacher, A., Schmidt, J., Drewke, C., Petersen, R. K., Kristiansen, Karsten, Ullrich, S., Kostenis, E., Kassack, M. U. & Ulven, Trond, 2010, In: ACS Medicinal Chemistry Letters. 1, 7, p. 345-349 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  103. Published

    beta-oxidation modulates metabolic competition between eicosapentaenoic acid and arachidonic acid regulating prostaglandin E(2) synthesis in rat hepatocytes-Kupffer cells

    Du, Z., Ma, T., Winterthun, S., Kristiansen, Karsten, Frøyland, L. & Madsen, L., 2010, In: BBA General Subjects. 1801, 4, p. 526-36 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. Published

    Epidermis-type lipoxygenase 3 regulates adipocyte differentiation and peroxisome proliferator-activated receptor gamma activity

    Hallenborg, P., Jørgensen, C., Petersen, R. K., Feddersen, S., Araujo, P., Markt, P., Langer, T., Furstenberger, G., Krieg, P., Koppen, A., Kalkhoven, E., Madsen, L. & Kristiansen, Karsten, 2010, In: Molecular and Cellular Biology. 30, 16, p. 4077-91 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  105. Published

    ADD1/SREBP1c activates the PGC1-alpha promoter in brown adipocytes

    Hao, Q., Hansen, Jacob B., Petersen, R. K., Hallenborg, P., Jørgensen, C., Cinti, S., Larsen, P. J., Steffensen, K. R., Wang, H., Collins, S., Wang, J., Gustafsson, J., Madsen, L. & Kristiansen, Karsten, 2010, In: BBA General Subjects. 1801, 4, p. 421-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  106. Published

    The MAPK-dependent regulation of the Jagged/Notch gene expression by VEGF, bFGF or PPAR gamma mediated angiogenesis in HUVEC

    Kiec-Wilk, B., Grzybowska-Galuszka, J., Polus, A., Pryjma, J., Knapp, A. & Kristiansen, Karsten, 2010, In: Journal of Physiology and Pharmacology. 61, 2, p. 217-25 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  107. Published

    Building the sequence map of the human pan-genome

    Li, R., Li, Y., Zheng, H., Luo, R., Zhu, H., Li, Q., Qian, W., Ren, Y., Tian, G., Li, J., Zhou, G., Zhu, X., Wu, H., Qin, J., Jin, X., Li, D., Cao, H., Hu, X., Blanche, H., Cann, H. & 7 others, Zhang, X., Li, S., Bolund, L., Kristiansen, Karsten, Yang, H., Wang, J. & Wang, J., 2010, In: Nature Biotechnology. 28, 1, p. 57-63 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 6489714