Karsten Kristiansen

Karsten Kristiansen

Professor

Member of:

    ORCID: 0000-0002-6024-0917

    Publication year:
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    201 - 300 out of 475Page size: 100
    1. 2012
    2. Published

      A comparative analysis of the intestinal metagenomes present in guinea pigs (Cavia porcellus) and humans (Homo sapiens)

      Hildebrand, F., Ebersbach, T., Nielsen, H. B., Li, X., Sonne, Si Brask, dos Santos, M. B. Q., Dimitrov, P., Madsen, L., Qin, J., Wang, J., Raes, J., Kristiansen, Karsten & Licht, T. R., 2012, In: B M C Genomics. 13, 514, 22 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      A metagenome-wide association study of gut microbiota in type 2 diabetes

      Qin, J., Li, Y., Cai, Z., Li, S., Zhu, J., Zhang, F., Liang, S., Zhang, W., Guan, Y., Shen, D., Peng, Y., Zhang, D., Jie, Z., Wu, W., Qin, Y., Xue, W., Li, J., Han, L., Lu, D., Wu, P. & 36 others, Dai, Y., Sun, X., Li, Z., Tang, A., Zhong, S., Li, X., Chen, W., Xu, R., Wang, M., Feng, Q., Gong, M., Yu, J., Zhang, Y., Zhang, M., Hansen, Torben, Sanchez, G., Raes, J., Falony, G., Okuda, S., Almeida, M., LeChatelier, E., Renault, P., Pons, N., Batto, J., Zhang, Z., Chen, H., Yang, R., Zheng, W., Li, S., Yang, H., Wang, J., Ehrlich, S. D., Nielsen, R., Pedersen, Oluf Borbye, Kristiansen, Karsten & Wang, J., 2012, In: Nature. 490, 7418, p. 55-60 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Activation of protein kinase A and exchange protein directly activated by cAMP promotes adipocyte differentiation of human mesenchymal stem cells

      Jia, B., Madsen, L., Petersen, R. K., Techer, N., Kopperud, R., Ma, T., Døskeland, S. O., Ailhaud, G., Wang, J., Amri, E. & Kristiansen, Karsten, 2012, In: P L o S One. 7, 3, 11 p., 0034114.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Dietary linoleic acid elevates endogenous 2-AG and anandamide and induces obesity

      Alvheim, A. R., Malde, M. K., Osei-Hyiaman, D., Lin, Y. H., Pawlosky, R. J., Madsen, L., Kristiansen, Karsten, Frøyland, L. & Hibbeln, J. R., 2012, In: Obesity. 20, 10, p. 1984-1994 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma

      Guo, G., Gui, Y., Gao, S., Tang, A., Hu, X., Huang, Y., Jia, W., Li, Z., He, M., Sun, L., Song, P., Sun, X., Zhao, X., Yang, S., Liang, C., Wan, S., Zhou, F., Chen, C., Zhu, J., Li, X. & 35 others, Jian, M., Zhou, L., Ye, R., Huang, P., Chen, J., Jiang, T., Liu, X., Wang, Y., Zou, J., Jiang, Z., Wu, R., Wu, S., Fan, F., Zhang, Z., Liu, L., Yang, R., Liu, X., Wu, H., Yin, W., Zhao, X., Liu, Y., Peng, H., Jiang, B., Feng, Q., Li, C., Xie, J., Lu, J., Kristiansen, Karsten, Li, Y., Zhang, X., Li, S., Wang, J., Yang, H., Cai, Z. & Wang, J., 2012, In: Nature Genetics. 44, 1, p. 17-19 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      High-glycemic index carbohydrates abrogate the antiobesity effect of fish oil in mice

      Hao, Q., Lillefosse, H. H., Fjære, E., Myrmel, L. S., Midtbø, L. K., Jarlsby, R. H., Ma, T., Jia, B., Petersen, R. K., Sonne, Si Brask, Chwalibog, André, Frøyland, L., Liaset, B., Kristiansen, Karsten & Madsen, L., 2012, In: American Journal of Physiology: Endocrinology and Metabolism. 302, 9, p. E1097-E1112 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Mammalian tissues defective in nonsense-mediated mRNA decay display highly aberrant splicing patterns

      Weischenfeldt, Joachim Lütken, Waage, J. E., Tian, G., Zhao, J., Damgaard, I., Jakobsen, J. S., Kristiansen, Karsten, Krogh, Anders, Wang, J. & Porse, Bo Torben, 2012, In: Genome Biology (Online Edition). 13, 5, 19 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Mdm2 controls CREB-dependent transactivation and initiation of adipocyte differentiation

      Hallenborg, P., Feddersen, S., Francoz, S., Murano, I., Sundekilde, U., Petersen, R. K., Akimov, V., Olson, M. V., Lozano, G., Cinti, S., Gjertsen, B. T., Madsen, L., Marine, J., Blagoev, B. & Kristiansen, Karsten, 2012, In: Cell Death and Differentiation. 19, 8, p. 1381-1389 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Of mice and men: factors abrogating the antiobesity effect of omega-3 fatty acids

      Madsen, L. & Kristiansen, Karsten, 2012, In: Adipocytes. 1, 3, p. 173-176 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      PPARgamma-PGC-1alpha activity is determinant of alcohol related breast cancer

      Petersen, R. K., Larsen, Signe Liv Benzon, Jensen, D. M., Christensen, J., Olsen, A., Loft, Steffen, Nellemann, C. L., Overvad, K., Kristiansen, Karsten, Tjønneland, A. & Vogel, U., 2012, In: Cancer Letters. 315, 1, p. 59-68 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Plant extracts of winter savory, purple coneflower, buckwheat and black elder activate PPAR-γ in COS-1 cells but do not lower blood glucose in Db/db Mice In vivo

      Schrader, E., Wein, S., Kristiansen, Karsten, Christensen, L. P., Rimbach, G. & Wolffram, S., 2012, In: Plant Foods for Human Nutrition. 67, 4, p. 377-383 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Resequencing 50 accessions of cultivated and wild rice yields markers for identifying agronomically important genes

      Xu, X., Liu, X., Ge, S., Jensen, J. D., Hu, F., Li, X., Dong, Y., Gutenkunst, R. N., Fang, L., Huang, L., Li, J., He, W., Zhang, G., Zheng, X., Zhang, F., Li, Y., Yu, C., Kristiansen, K., Zhang, X., Wang, J. & 5 others, Wright, M., McCouch, S., Nielsen, Rasmus, Wang, J. & Wang, W., 2012, In: Nature Biotechnology. 30, 1, p. 105-111 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm

      Hou, Y., Song, L., Zhu, P., Zhang, B., Tao, Y., Xu, X., Li, F., Wu, K., Liang, J., Shao, D., Wu, H., Ye, X., Ye, C., Wu, R., Jian, M., Chen, Y., Xie, W., Zhang, R., Chen, L., Liu, X. & 20 others, Yao, X., Zheng, H., Yu, C., Li, Q., Gong, Z., Mao, M., Yang, X., Yang, L., Li, J., Wang, W., Lu, Z., Gu, N., Laurie, G., Bolund, L., Kristiansen, Karsten, Wang, J., Yang, H., Li, Y., Zhang, X. & Wang, J., 2012, In: Cell. 148, 5, p. 873-885 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor: Cell

      Xu, X., Hou, Y., Yin, X., Bao, L., Tang, A., Song, L., Li, F., Tsang, S., Wu, K., Wu, H., He, W., Zeng, L., Xing, M., Wu, R., Jiang, H., Liu, X., Cao, D., Guo, G., Hu, X., Gui, Y. & 19 others, Li, Z., Xie, W., Sun, X., Shi, M., Cai, Z., Wang, B., Zhong, M., Li, J., Lu, Z., Gu, N., Zhang, X., Goodman, L., Bolund, L., Wang, J., Yang, H., Kristiansen, Karsten, Dean, M., Li, Y. & Wang, J., 2012, In: Cell. 148, 5, p. 886-895 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Single-cell sequencing analysis characterizes common and cell-lineage-specific mutations in a muscle-invasive bladder cancer

      Li, Y., Xu, X., Song, L., Hou, Y., Li, Z., Tsang, S., Li, F., Im, K., Wu, K., Wu, H., Ye, X., Li, G., Wang, L., Zhang, B., Liang, J., Xie, W., Wu, R., Jiang, H., Liu, X., Yu, C. & 20 others, Zheng, H., Jian, M., Nie, L., Wan, L., Shi, M., Sun, X., Tang, A., Guo, G., Gui, Y., Cai, Z., Li, J., Wang, W., Lu, Z., Zhang, X., Bolund, L., Kristiansen, Karsten, Wang, J., Yang, H., Dean, M. & Wang, J., 2012, In: GigaScience. 1, 12, 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Transcriptome and network changes in climbers at extreme altitudes

      Chen, F., Zhang, W., Liang, Y., Huang, J., Li, K., Green, C. D., Liu, J., Zhang, G., Zhou, B., Yi, X., Wang, W., Liu, H., Xu, X., Shen, F., Qu, N., Wang, Y., Gao, G., San, A., JiangBai, L., Sang, H. & 6 others, Fang, X., Kristiansen, Karsten, Yang, H., Wang, J., Han, J. J. & Wang, J., 2012, In: P L o S One. 7, 2, p. e31645-e31645

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. 2013
    19. Published

      2-heptyl-formononetin increases cholesterol and induces hepatic steatosis in mice

      Andersen, C., Schjoldager, J. G., Tortzen, C., Vegge, A., Hufeldt, M. R., Skaanild, M. T., Vogensen, Finn Kvist, Kristiansen, Karsten, Hansen, Axel Kornerup & Nielsen, J., 2013, In: Journal of Biomedicine and Biotechnology. 2013, 13 p., 926942.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      A short-read multiplex sequencing method for reliable, cost-effective and high-throughput genotyping in large-scale studies: [plus] Erratum

      Cao, H., Wang, Y., Zhang, W., Chai, X., Zhang, X., Chen, S., Yang, F., Zhang, C., Guo, Y., Liu, Y., Tang, Z., Chen, C., Xue, Y., Zhen, H., Xu, Y., Rao, B., Liu, T., Zhao, M., Zhang, W., Li, Y. & 6 others, Zhang, X., Tellier, L. C. A. M., Krogh, Anders, Kristiansen, Karsten, Wang, J. & Li, J., 2013, In: Human Mutation. 34, 12, p. 1715-1720 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Bioactive components from flowers of Sambucus nigra L. increase glucose uptake in primary porcine myotube cultures and reduce fat accumulation in Caenorhabditis elegans

      Bhattacharya, S., Christensen, K. B., Olsen, L. C. B., Christensen, L. P., Grevsen, K., Færgeman, N. J., Kristiansen, Karsten, Young, J. F. & Oksbjerg, N., 2013, In: Journal of Agricultural and Food Chemistry. 61, 46, p. 11033-11040 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Dietary eicosapentaenoic acid supplementation accentuates hepatic triglyceride accumulation in mice with impaired fatty acid oxidation capacity

      Du, Z., Ma, Tao, Liaset, B., Keenan, A. H., Araujo, P., Lock, E., Demizieux, L., Degrace, P., Frøyland, L., Kristiansen, Karsten & Madsen, L., 2013, In: B B A - Molecular and Cell Biology of Lipids. 1831, 2, p. 291-299 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Discovery of a novel selective PPARγ ligand with partial agonist binding properties by integrated in Silico/in Vitro work flow

      Kouskoumvekaki, I., Petersen, R. K., Fratev, F. F., Taboureau, O., Nielsen, T. E., Oprea, T., Sonne, Si Brask, Flindt, E. N., Jonsdottir, S. O. & Kristiansen, Karsten, 2013, In: Journal of Chemical Information and Modeling. 53, 4, p. 923-937 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Discovery of new PPARγ agonists based on arylopeptoids

      Worm-Leonhard, K., Hjelmgaard, T., Petersen, R. K., Kristiansen, Karsten & Nielsen, J., 2013, In: Bioorganic & Medicinal Chemistry Letters. 23, p. 4162-4165 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes

      Albrechtsen, A., Grarup, N., Li, Y., Sparsø, T. H., Tian, G., Cao, H., Jiang, T., Kim, S. Y., Korneliussen, T. S., Li, Q., Nie, C., Wu, R., Skotte, L., Morris, A. P., Ladenvall, C., Cauchi, S., Stancáková, A., Andersen, G., Astrup, A., Banasik, K. & 86 others, Bennett, A. J., Bolund, L., Charpentier, G., Chen, Y., Dekker, J. M., Doney, A. S. F., Dorkhan, M., Forsen, T., Frayling, T. M., Groves, C. J., Gui, Y., Hallmans, G., Hattersley, A. T., He, K., Hitman, G. A., Holmkvist, J., Huang, S., Jiang, H., Jin, X., Justesen, Johanne Marie, Kristiansen, Karsten, Kuusisto, J., Lajer, M., Lantieri, O., Li, W., Liang, H., Liao, Q., Liu, X., Ma, T., Ma, X., Manijak, M. P., Marre, M., Mokrosinski, J., Morris, A. D., Mu, B., Nielsen, A. A., Nijpels, G., Nilsson, P., Palmer, C. N. A., Rayner, N. W., Renström, F., Ribel-Madsen, R., Robertson, N., Rolandsson, O., Rossing, P., Schwartz, Thue W., Slagboom, P. E., Sterner, M., Tang, M., Tarnow, L., Tuomi, T., Van't Riet, E., van Leeuwen, N., V Varga, Tibor, Vestmar, M. A., Walker, M., Wang, B., Wang, Y., Wu, H., Xi, F., Yengo, L., Yu, C., Zhang, X., Zhang, J., Zhang, Q., Zhang, W., Zheng, H., Zhou, Y., Altshuler, D., 't Hart, L. M., Franks, P. W., Balkau, B., Froguel, P., McCarthy, M. I., Laakso, M., Groop, L., Christensen, C., Brandslund, I., Lauritzen, T., Witte, D. R., Linneberg, A., Jørgensen, T., Hansen, Torben, Wang, J., Nielsen, Rasmus & Pedersen, Oluf Borbye, 2013, In: Diabetologia. 56, 2, p. 298-310 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets

      Grarup, N., Sulem, P., Sandholt, C. H., Thorleifsson, G., Ahluwalia, T. V. S., Steinthorsdottir, V., Bjarnason, H., Gudbjartsson, D. F., Magnusson, O. T., Sparsø, T., Albrechtsen, A., Kong, A., Masson, G., Tian, G., Cao, H., Nie, C., Kristiansen, K., Husemoen, L. L., Thuesen, B., Li, Y. & 10 others, Nielsen, Rasmus, Linneberg, Allan René, Olafsson, I., Eyjolfsson, G. I., Jørgensen, T., Wang, J., Hansen, Torben, Thorsteinsdottir, U., Stefánsson, K. & Pedersen, Oluf Borbye, 2013, In: P L o S Genetics. 9, 6, 12 p., e1003530.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Hydrolyzed Casein Reduces Diet-Induced Obesity in Male C57BL/6J Mice

      Lillefosse, H. H., Tastesen, H. S., Du, Z., Ditlev, D. B., Thorsen, F. A., Madsen, L., Kristiansen, Karsten & Liaset, B., 2013, In: The Journal of Nutrition. 143, 9, p. 1367-1375 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Intake of farmed Atlantic salmon fed soybean oil increases insulin resistance and hepatic lipid accumulation in mice

      Midtbø, L. K., Ibrahim, M. M., Myrmel, L. S., Aune, U. L., Alvheim, A. R., Liland, N. S., Torstensen, B. E., Rosenlund, G., Liaset, B., Brattelid, T., Kristiansen, Karsten & Madsen, L., 2013, In: P L o S One. 8, 1, 11 p., e53094.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration

      Veland, I. R., Montjean, R., Eley, L., Pedersen, Lotte Bang, Schwab, A., Goodship, J., Kristiansen, Karsten, Pedersen, Stine Helene Falsig, Saunier, S. & Christensen, Søren Tvorup, 2013, In: P L o S One. 8, 4, 15 p., e60193.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Mælk der slanker? Mælk som regulator af lipidmetabolisme og overvægt. Afdækning af mælks evne til at øge faste-induceret adipose faktor (FIAF)-aktivitet

      Nielsen, S. D., Dalsgaard, T. K., Mortensen, G., Lorenzen, J. K., Astrup, A., Kristiansen, Karsten & Madsen, L., 2013, In: Maelkeritidende. 2, p. 8-9 2 p.

      Research output: Contribution to journal › Journal article › Communication

    31. Published

      Profiling of lipid species by normal-phase liquid chromatography, nanoelectrospray ionization, and ion trap-orbitrap mass spectrometry

      Sokol, E., Almeida, R., Hannibal-Bach, H. K., Kotowska, D. E., Vogt, J., Baumgart, J., Kristiansen, Karsten, Nitsch, R., Knudsen, J. & Ejsing, C. S., 2013, In: Analytical Biochemistry. 443, 1, p. 88-96 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Richness of human gut microbiome correlates with metabolic markers

      Le Chatelier, E., Nielsen, T., Qin, J., Prifti, E., Hildebrand, F., Falony, G., Almeida, M., Arumugam, M., Batto, J-M., Kennedy, S., Leonard, P., Li, J., Burgdorf, K. S., Grarup, N., Jørgensen, T., Brandslund, I., Nielsen, H. B., Juncker, A., dos Santos, M. B. Q., Levenez, F. & 62 others, Pons, N., Rasmussen, Simon, Sunagawa, S., Tap, J., Tims, S., Zoetendal, E. G., Brunak, S., Clément, K., Doré, J., Kleerebezem, M., Kristiansen, Karsten, Renault, P., Sicheritz-Ponten, T., de Vos, W. M., Zucker, J., Raes, J., Hansen, Torben, Bork, P., Wang, J., Ehrlich, S. D., Pedersen, Oluf Borbye, Guedon, E., Delorme, C., Layec, S., Khaci, G., van de Guchte, M., Vandemeulebrouck, G., Jamet, A., Dervyn, R., Sanchez, N., Maguin, E., Haimet, F., Winogradski, Y., Cultrone, A., Leclerc, M., Juste, C., Blottière, H., Pelletier, E., LePaslier, D., Artiguenave, F., Bruls, T., Weissenbach, J., Turner, K., Parkhill, J., Antolin, M., Manichanh, C., Casellas, F., Boruel, N., Varela, E., Torrejon, A., Guarner, F., Denariaz, G., Derrien, M., van Hylckama Vlieg, J. E. T., Veiga, P., Oozeer, R., Knol, J., Rescigno, M., Brechot, C., Mérieux, A., M'Rini, C. & Yamada, T., 2013, In: Nature. 500, 7464, p. 541-546 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Ursolic acid induces cell death and modulates autophagy through JNK pathway in apoptosis-resistant colorectal cancer cells

      Xavier, C. P. R., Lima, C. F., Pedro, D. F. N., Wilson, J. M., Kristiansen, Karsten & Pereira-Wilson, C., 2013, In: Journal of Nutritional Biochemistry. 24, 4, p. 706-712 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes

      Lohmueller, K. E., Sparsø, T. H., Li, Q., Galijatovic, E. A. A., Korneliussen, T. S., Albrechtsen, A., Banasik, K., Grarup, N., Hallgrimsdottir, I., Kiil, K., Oskari Kilpeläinen, T., Krarup, N. T., Pers, T. H., Sanchez, G., Hu, Y., DeGiorgio, M., Jørgensen, T., Sandbæk, A., Lauritzen, T., Brunak, S. & 6 others, Kristiansen, Karsten, Li, Y., Hansen, Torben, Wang, J., Nielsen, Rasmus & Pedersen, Oluf Borbye, 5 Dec 2013, In: American Journal of Human Genetics. 93, 6, p. 1072-1086 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. 2014
    36. Published

      2-(2-Bromophenyl)-formononetin and 2-heptyl-formononetin are PPARγ partial agonists and reduce lipid accumulation in 3T3-L1 adipocytes

      Andersen, C., Kotowska, D. E., Tortzen, C., Kristiansen, Karsten, Nielsen, J. & Petersen, R. K., 2014, In: Bioorganic and Medicinal Chemistry. 22, 21, p. 6105-6111 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      A Mixture of cod and scallop protein reduces adiposity and improves glucose tolerance in high-fat fed male C57BL/6J mice

      Tastesen, H. S., Rønnevik, A. K., Borkowski, K., Madsen, L., Kristiansen, Karsten & Liaset, B., 2014, In: P L o S One. 9, 11, 12 p., e112859.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Activation of the angiopoietin-like 4 (ANGPLT4) gene by milk fat and casein

      Nielsen, S. D., Young, J. F., Mortensen, G., Petersen, R. K., Kristiansen, Karsten & Dalsgaard, T. K., 2014, In: International Dairy Journal. 36, 2, p. 136-142 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      An integrated catalog of reference genes in the human gut microbiome

      Li, J., Jia, H., Cai, X., Zhong, H., Feng, Q., Sunagawa, S., Arumugam, M., Kultima, J. R., Prifti, E., Nielsen, T., Juncker, A., Manichanh, C., Chen, B., Zhang, W., Levenez, F., Wang, J., Xu, X., Xiao, L., Liang, S., Zhang, D. & 17 others, Zhang, Z., Chen, W., Zhao, H., Al-Aama, J. Y., Edris, S., Yang, H., Wang, J., Hansen, Torben, Nielsen, H. B., Brunak, S., Kristiansen, Karsten, Guarner, F., Pedersen, Oluf Borbye, Doré, J., Ehrlich, S. D., Bork, P. & Wang, J., 2014, In: Nature Biotechnology. 32, 8, p. 834-845 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes

      Nielsen, H. B., Almeida, M., Juncker, A., Rasmussen, S., Li, J., Sunagawa, S., Plichta, D. R., Gautier, L., Pedersen, A. G., Le Chatelier, E., Pelletier, E., Bonde, I., Nielsen, T., Manichanh, C., Arumugam, M., Batto, J-M., dos Santos, M. B. Q., Blom, N., Borruel, N., Burgdorf, K. S. & 31 others, Boumezbeur, F., Casellas, F., Doré, J., Dworzynski, P., Guarner, F., Hansen, Torben, Hildebrand, F., Kaas, R. S., Kennedy, S., Kristiansen, Karsten, Kultima, J. R., Léonard, P., Levenez, F., Lund, O., Moumen, B., Le Paslier, D., Pons, N., Pedersen, Oluf Borbye, Prifti, E., Qin, J., Raes, J., Sørensen, Søren Johannes, Tap, J., Tims, S., Ussery, D., Yamada, T., Renault, P., Sicheritz-Pontén, T., Bork, P., Wang, J. & MetaHIT Consortium, M. C., 2014, In: Nature Biotechnology. 32, 8, p. 822–828 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Identification of odorant-receptor interactions by global mapping of the human odorome

      Audouze, K. M. L., Tromelin, A., Le Bon, A. M., Belloir, C., Petersen, R. K., Kristiansen, Karsten, Brunak, Søren & Taboureau, O., 2014, In: PLOS ONE. 9, 4, p. e93037 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Indomethacin treatment prevents high fat diet-induced obesity and insulin resistance but not glucose intolerance in C57BL/6J Mice

      Fjære, E., Aune, U. L., Røen, K., Keenan, A. H., Ma, Tao, Borkowski, K., Kristensen, D. M. B., Novotny, G. W., Mandrup-Poulsen, Thomas, Hudson, B. D., Milligan, G., Xi, Y., Newman, J. W., Haj, F. G., Liaset, B., Kristiansen, Karsten & Madsen, L., 2014, In: The Journal of Biological Chemistry. 289, 23, p. 16032-16045 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Isomeric C-12-Alkamides from the roots of Echinacea purpurea improve basal and insulin-dependent glucose uptake in 3T3-L1 adipocytes

      Kotowska, D. E., El-Houri, R. B., Borkowski, K., Petersen, R. K., Fretté, X., Wolber, G., Grevsen, K., Christensen, K. B., Christensen, L. P. & Kristiansen, Karsten, 2014, In: Planta Medica. 80, 18, p. 1712-1720 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Molecular aspects of adipoepithelial transdifferentiation in mouse mammary gland

      Prokesch, A., Smorlesi, A., Perugini, J., Manieri, M., Ciarmela, P., Mondini, E., Trajanoski, Z., Kristiansen, Karsten, Giordano, A., Bogner-Strauss, J. G. & Cinti, S., 2014, In: Stem Cells. 32, 10, p. 2756-2766 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Multi-block PCA and multi-compartmental study of the metabolic responses to intake of hydrolysed versus intact casein in C57BL/6J mice by NMR-based metabolomics

      Yde, C. C., Clausen, M. R., Ditlev, D. B., Lillefosse, H., Madsen, L., Kristiansen, Karsten, Liaset, B. & Bertram, H. C. S., 2014, In: Metabolomics. 10, 5, p. 938-949 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      PPARγ ligand production is tightly linked to clonal expansion during initiation of adipocyte differentiation

      Hallenborg, P., Petersen, R. K., Feddersen, S., Sundekilde, U. K., Hansen, Jacob B., Blagoev, B., Madsen, L. & Kristiansen, Karsten, 2014, In: Journal of Lipid Research. 55, 12, p. 2491-2500 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Proteomic analysis of cAMP-mediated signaling during differentiation of 3 T3-L1 preadipocytes

      Borkowski, K., Wrzesinski, K., Rogowska-Wrzesinska, A., Audouze, K. M. L., Bakke, J., Petersen, R. K., Haj, F. G., Madsen, L. & Kristiansen, Karsten, 2014, In: B B A - Proteins and Proteomics. 1844, 12, p. 2096-2107 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Scallop protein with endogenous high taurine and glycine content prevents high-fat, high-sucrose-induced obesity and improves plasma lipid profile in male C57BL/6J mice

      Tastesen, H. S., Keenan, A. H., Madsen, L., Kristiansen, Karsten & Liaset, B., 2014, In: Amino Acids. 46, 7, p. 1659-1671 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Screening for bioactive metabolites in plant extracts modulating glucose uptake and fat accumulation

      El-Houri, R. B., Kotowska, D. E., Olsen, L. C. B., Bhattacharya, S., Christensen, L. P., Grevsen, K., Oksbjerg, N., Færgeman, N. J., Kristiansen, Karsten & Christensen, K. B., 2014, In: Evidence - Based Complementary and Alternative Medicine. 2014, 8 p., 156398.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      The sheep genome illuminates biology of the rumen and lipid metabolism

      Jiang, Y., Xie, M., Chen, W., Talbot, R., Maddox, J. F., Faraut, T., Wu, C., Muzny, D. M., Li, Y., Zhang, W., Stanton, J-A., Brauning, R., Barris, W. C., Hourlier, T., Aken, B. L., Searle, S. M. J., Adelson, D. L., Bian, C., Cam, G. R., Chen, Y. & 53 others, Cheng, S., DeSilva, U., Dixen, K., Dong, Y., Fan, G., Franklin, I. R., Fu, S., Fuentes-Utrilla, P., Guan, R., Highland, M. A., Holder, M. E., Huang, G., Ingham, A. B., Jhangiani, S. N., Kalra, D., Kovar, C. L., Lee, S. L., Liu, W., Liu, X., Lu, C., Lv, T., Mathew, T., McWilliam, S., Menzies, M., Pan, S., Robelin, D., Servin, B., Townley, D., Wang, W., Wei, B., White, S. N., Yang, X., Ye, C., Yue, Y., Zeng, P., Zhou, Q., Hansen, Jacob B., Kristiansen, Karsten, Gibbs, R. A., Flicek, P., Warkup, C. C., Jones, H. E., Oddy, V. H., Nicholas, F. W., McEwan, J. C., Kijas, J. W., Wang, J., Worley, K. C., Archibald, A. L., Cockett, N., Xu, X., Wang, W. & Dalrymple, B. P., 2014, In: Science. 344, 6188, p. 1168-1173 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. Published

      Urinary loss of tricarboxylic acid cycle intermediates as revealed by metabolomics studies: an underlying mechanism to reduce lipid accretion by whey protein ingestion?

      Lillefosse, H. H., Clausen, M. R., Yde, C. C., Ditlev, D. B., Zhang, X., Du, Z., Bertram, H. C. S., Madsen, L., Kristiansen, Karsten & Liaset, B., 2014, In: Journal of Proteome Research. 13, 5, p. 2560-2570 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. Published

      Variation and association to diabetes in 2000 full mtDNA sequences mined from an exome study in a Danish population

      Li, S., Besenbacher, S., Li, Y., Kristiansen, Karsten, Grarup, Niels, Albrechtsen, Anders, Sparsø, T. H., Korneliussen, Thorfinn Sand, Hansen, Torben, Wang, J., Nielsen, Rasmus, Pedersen, Oluf Borbye, Bolund, L. & Schierup, M. H., 2014, In: European Journal of Human Genetics. 22, p. 1040-1045 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    53. Published

      Weight cycling promotes fat gain and altered clock gene expression in adipose tissue in C57BL/6J mice

      Dankel, S. N., Degerud, E. M., Borkowski, K., Fjære, E., Midtbø, L. K., Haugen, C., Solsvik, M. H., Lavigne, A. M., Liaset, B., Sagen, J. V., Kristiansen, Karsten, Mellgren, G. & Madsen, L., 2014, In: American Journal of Physiology: Endocrinology and Metabolism. 306, 2, p. E210-E224 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    54. 2015
    55. Published

      De novo assembly of a haplotype-resolved human genome

      Cao, H., Wu, H., Luo, R., Huang, S., Sun, Y., Tong, X., Xie, Y., Liu, B., Yang, H., Zheng, H., Li, J., Li, B., Wang, Y., Yang, F., Sun, P., Liu, S., Gao, P., Huang, H., Sun, J., Chen, D. & 21 others, He, G., Huang, W., Huang, Z., Li, Y., Tellier, L. C. A. M., Liu, X., Feng, Q., Xu, X., Zhang, X., Bolund, L., Krogh, Anders, Kristiansen, Karsten, Drmanac, R., Drmanac, S., Nielsen, R., Li, S., Wang, J., Yang, H., Li, Y., Wong, G. K. & Wang, J., 2015, In: Nature Biotechnology. 33, 6, p. 617-626 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    56. Published

      A catalog of the mouse gut metagenome: [incl. Author Correction]

      Xiao, L., Feng, Q., Liang, S., Sonne, S. B., Xia, Z., Qiu, X., Li, X., Long, H., Zhang, J., Zhang, D., Liu, C., Fang, Z., Chou, J., Glanville, J., Hao, Q., Kotowska, D. E., Colding, C. S., Licht, T. R., Wu, D., Yu, J. & 17 others, Sung, J. J. Y., Liang, Q., Li, J., Jia, H., Lan, Z., Tremaroli, V., Dworzynski, P., Nielsen, H. B., Bäckhed, G. F., Dore, J., Le Chatelier, E., Ehrlich, S. D., Lin, J. C., Arumugam, Mani, Wang, J., Madsen, L. & Kristiansen, Karsten, 2015, In: Nature Biotechnology. 33, 10, p. 1103-1108 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    57. Published

      Aniline is rapidly converted into Paracetamol impairing male reproductive development

      Holm, J. B., Chalmey, C., Modick, H., Jensen, L. S., Dierkes, G., Weiss, T., Jensen, Benjamin Anderschou Holbech, Nørregard, M. M., Borkowski, K., Styrishave, Bjarne, Koch, H. M., Mazaud-Guittot, S., Jegou, B., Kristiansen, Karsten & Kristensen, D. M., 2015, In: Toxicological Sciences. 148, 1, p. 288-298 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    58. Published

      Chronic Trichuris muris infection decreases diversity of the intestinal microbiota and concomitantly increases the abundance of lactobacilli

      Holm, J. B., Sorobetea, D., Kiilerich, P., Ramayo-Caldas, Y., Estellé, J., Ma, Tao, Madsen, L., Kristiansen, Karsten & Svensson-Frej, M., 2015, In: PLOS ONE. 10, 5, 22 p., e0125495.

      Research output: Contribution to journal › Journal article › Research › peer-review

    59. Published

      Dietary n-6 PUFA, carbohydrate: protein ratio and change in body weight and waist circumference: a follow-up study

      Jakobsen, M. U., Madsen, L., Dethlefsen, C., Due, K. M., Halkjaer, J., Sørensen, Thorkild I.A., Kristiansen, Karsten & Overvad, K., 2015, In: Public Health Nutrition. 18, 07, p. 1317-1323 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    60. Published

      Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

      Forslund, K., Hildebrand, F., Nielsen, T., Falony, G., Le Chatelier, E., Sunagawa, S., Prifti, E., Vieira-Silva, S., Gudmundsdottir, V., Pedersen, H. K., Arumugam, M., Kristiansen, K., Yvonne Voigt, A., Vestergaard, H., Hercog, R., Igor Costea, P., Roat Kultima, J., Li, J., Jørgensen, T., Levenez, F. & 9 others, Dore, J., Nielsen, H. B., Brunak, Søren, Raes, J., Hansen, Torben, Wang, J., Dusko Ehrlich, S., Bork, P. & Pedersen, Oluf Borbye, 2015, In: Nature. 528, 7581, p. 262-266 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    61. Published

      Dynamics and stabilization of the human gut microbiome during the first year of life

      Bäckhed, G. F., Roswall, J., Peng, Y., Feng, Q., Jia, H., Kovatcheva-Datchary, P., Li, Y., Xia, Y., Xie, H., Zhong, H., Khan, M. T., Zhang, J., Li, J., Xiao, L., Al-Aama, J., Zhang, D., Lee, Y. S., Kotowska, D. E., Colding, C. S., Tremaroli, V. & 7 others, Yin, Y., Bergman, S., Xu, X., Madsen, L., Kristiansen, Karsten, Dahlgren, J. & Wang, J., 2015, In: Cell Host & Microbe. 17, 5, p. 690-703 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    62. Published

      Full-length single-cell RNA-seq applied to a viral human cancer: applications to HPV expression and splicing analysis in HeLa S3 cells

      Wu, L., Zhang, X., Zhao, Z., Wang, L., Li, B., Li, G., Dean, M., Yu, Q., Wang, Y., Lin, X., Rao, W., Mei, Z., Li, Y., Jiang, R., Yang, H., Li, F., Xie, G., Xu, L., Wu, K., Zhang, J. & 9 others, Chen, J., Wang, T., Kristiansen, Karsten, Zhang, X., Li, Y., Yang, H., Wang, J., Hou, Y. & Xu, X., 2015, In: GigaScience. 4, 17 p., 51.

      Research output: Contribution to journal › Journal article › Research › peer-review

    63. Published

      Global gene expression profiling of brown to white adipose tissue transformation in sheep reveals novel transcriptional components linked to adipose remodeling

      Basse, A. L., Dixen, K., Yadav, R., Tygesen, M. P., Qvortrup, Klaus, Kristiansen, Karsten, Quistorff, B., Gupta, R., Wang, J. & Hansen, Jacob B., 2015, In: BMC Genomics. 16, 19 p., 215.

      Research output: Contribution to journal › Journal article › Research › peer-review

    64. Published

      Gut microbiome development along the colorectal adenoma-carcinoma sequence

      Feng, Q., Liang, S., Jia, H., Stadlmayr, A., Tang, L., Lan, Z., Zhang, D., Xia, H., Xu, X., Jie, Z., Su, L., Li, X., Li, X., Li, J., Xiao, L., Huber-Schönauer, U., Niederseer, D., Xu, X., Al-Aama, J. Y., Yang, H. & 6 others, Wang, J., Kristiansen, Karsten, Arumugam, Mani, Tilg, H., Datz, C. & Wang, J., 2015, In: Nature Communications. 6, 13 p., 6528.

      Research output: Contribution to journal › Journal article › Research › peer-review

    65. Published

      In vitro screening of inhibition of PPAR-γ activity as a first step in identification of potential breast carcinogens

      Kopp, T. I., Lundqvist, J., Petersen, R. K., Oskarsson, A., Kristiansen, Karsten, Nellemann, C. & Vogel, U., 2015, In: Human & Experimental Toxicology. 34, 11, p. 1106-1118 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    66. Published

      Intake of farmed Atlantic salmon fed soybean oil increases hepatic levels of arachidonic acid-derived oxylipins and ceramides in mice

      Midtbø, L. K., Borkowska, A. G., Bernhard, A., Rønnevik, A. K., Lock, E., Fitzgerald, M. L., Torstensen, B. E., Liaset, B., Brattelid, T., Pedersen, T. L., Newman, J. W., Kristiansen, Karsten & Madsen, L., 2015, In: Journal of Nutritional Biochemistry. 26, 6, p. 585-595 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    67. Published

      Intake of hydrolyzed casein is associated with reduced dody fat accretion and enhanced phase II metabolism in obesity prone C57BL/6J mice

      Clausen, M. R., Zhang, X., Yde, C. C., Ditlev, D. B., Lillefosse, H. H., Madsen, L., Kristiansen, Karsten, Liaset, B. & Bertram, H. C., 2015, In: P L o S One. 10, 3, 18 p., e0118895.

      Research output: Contribution to journal › Journal article › Research › peer-review

    68. Published

      Medium chain fatty acids from milk induce angiopoietin-like 4 (ANGPTL4) gene expression

      Nielsen, S. D., Amer, B., Young, J. F., Mortensen, G., Petersen, R. K., Kristiansen, Karsten & Dalsgaard, T. K., 2015, In: International Dairy Journal. 42, p. 34-41 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    69. Published

      MicroRNA-455 regulates brown adipogenesis via a novel HIF1an-AMPK-PGC1α signaling network

      Zhang, H., Guan, M., Townsend, K. L., Huang, T. L., An, D., Yan, X., Xue, R., Schulz, T. J., Winnay, J., Mori, M., Hirshman, M. F., Kristiansen, Karsten, Tsang, J. S., White, A. P., Cypess, A. M., Goodyear, L. J. & Tseng, Y., 2015, In: E M B O Reports. 16, 10, p. 1378-1393 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    70. Published

      Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios

      Besenbacher, S., Liu, S., Gonzalez-Izarzugaza, J. M., Grove, J., Belling, K. G., Bork-Jensen, J., Huang, S., Als, T. D., Li, S., Yadav, R., Rubio García, A., Lescai, F., Demontis, D., Rao, J., Ye, W., Mailund, T., Møllegaard Friborg, R., Pedersen, C. N. S., Xu, R., Sun, J. & 27 others, Liu, H., Wang, O., Cheng, X., Flores, D., Rydza, E. K., Rapacki, K., Sørensen, J. D., Chmura, P. J., Westergaard, David, Dworzynski, P., Sørensen, Thorkild I.A., Lund, O., Hansen, Torben, Xu, X., Li, N., Bolund, L., Pedersen, Oluf Borbye, Eiberg, Hans Rudolf Lytchoff, Krogh, Anders, Børglum, A. D., Brunak, Søren, Kristiansen, Karsten, Schierup, M. H., Wang, J., Gupta, R., Villesen, P. & Rasmussen, Simon, 2015, In: Nature Communications. 6, 9 p., 5969.

      Research output: Contribution to journal › Journal article › Research › peer-review

    71. Published

      Polyacetylenes from carrots (Daucus carota) improve glucose uptake in vitro in adipocytes and myotubes

      El-Houri, R. B., Kotowska, D. E., Christensen, K. B., Bhattacharya, S., Oksbjerg, N., Wolber, G., Kristiansen, Karsten & Christensen, L. P., 2015, In: Food & Function. 6, 7, p. 2135-2144 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    72. Published

      The oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment

      Zhang, X., Zhang, D., Jia, H., Feng, Q., Wang, D., Liang, D., Wu, X., Li, J., Tang, L., Li, Y., Lan, Z., Chen, B., Li, Y., Zhong, H., Xie, H., Jie, Z., Chen, W., Tang, S., Xu, X., Wang, X. & 28 others, Cai, X., Liu, S., Xia, Y., Li, J., Qiao, X., Al-Aama, J. Y., Chen, H., Wang, L., Wu, Q., Zhang, F., Zheng, W., Li, Y., Zhang, M., Luo, G., Xue, W., Xiao, L., Li, J., Chen, W., Xu, X., Yin, Y., Yang, H., Wang, J., Kristiansen, Karsten, Liu, L., Li, T., Huang, Q., Li, Y. & Wang, J., 2015, In: Nature Medicine. 21, 8, p. 895-905 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    73. Published

      Tissue inhibitor of matrix metalloproteinase-1 is required for high-fat diet-induced glucose intolerance and hepatic steatosis in mice

      Fjære, E., Andersen, C., Myrmel, L. S., Petersen, R. K., Hansen, J. B., Tastesen, H. S., Mandrup-Poulsen, Thomas, Brünner, N., Kristiansen, Karsten, Madsen, L. & Rømer, M. U. K., 2015, In: PloS one. 10, 7, 19 p., e0132910.

      Research output: Contribution to journal › Journal article › Research › peer-review

    74. Published

      Transcriptome profiling of brown adipose tissue during cold exposure reveals extensive regulation of glucose metabolism

      Hao, Q., Yadav, R., Basse, A. L., Petersen, S., Sonne, Si Brask, Rasmussen, Simon, Zhu, Q., Lu, Z., Wang, J., Audouze, K., Gupta, R., Madsen, L., Kristiansen, Karsten & Hansen, Jacob B., 2015, In: American Journal of Physiology: Endocrinology and Metabolism. 308, 5, p. E380-E392 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    75. 2016
    76. Published

      A randomised, controlled, crossover study of the effect of diet on angiopoietin-like protein 4 (ANGPTL4) through modification of the gut microbiome

      Blædel, T., Holm, J. B., Sundekilde, U. K., Schmedes, M. S., Hess, A. L., Lorenzen, J. K., Kristiansen, Karsten, Dalsgaard, T. K., Astrup, A. & Larsen, L. H., 2016, In: Journal of Nutritional Science. 5, 10 p., e45.

      Research output: Contribution to journal › Journal article › Research › peer-review

    77. Published

      A reference gene catalogue of the pig gut microbiome

      Xiao, L., Estellé, J., Kiilerich, P., Ramayo-Caldas, Y., Xia, Z., Feng, Q., Liang, S., Pedersen, A. Ø., Kjeldsen, N. J., Liu, C., Maguin, E., Doré, J., Pons, N., Le Chatelier, E., Prifti, E., Li, J., Jia, H., Liu, X., Xu, X., Ehrlich, S. D. & 4 others, Madsen, L., Kristiansen, Karsten, Rogel-Gaillard, C. & Wang, J., 2016, In: Nature Microbiology. 1, 6 p., 16161.

      Research output: Contribution to journal › Letter › Research › peer-review

    78. Published

      Depletion of regulatory T cells leads to an exacerbation of delayedtype hypersensitivity arthritis in C57BL/6 mice that can be counteracted by IL-17 blockade

      Atkinson, S. M., Hoffmann, U., Bach, E., Danneskiold-Samsøe, Niels Banhos, Kristiansen, Karsten, Serikawa, K., Fox, B., Kruse, K., Haase, C., Skov, Søren & Nansen, A., 2016, In: Disease Models & Mechanisms. 9, p. 427-440 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    79. Published

      Design and synthesis of novel Y-shaped barbituric acid derivatives as PPARγ activators

      Dixit, V. A., Rathi, P. C., Bhagat, S., Gohlke, H., Petersen, R. K., Kristiansen, Karsten, Chakraborti, A. K. & Bharatam, P. V., 2016, In: European Journal of Medicinal Chemistry. 108, p. 423-435 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    80. Published

      Dietary fat drives whole-body insulin resistance and promotes intestinal inflammation independent of body weight gain

      Jensen, Benjamin Anderschou Holbech, Nielsen, Thomas Svava, Fritzen, Andreas Mæchel, Holm, J. B., Fjære, E., Serup, A. K. L., Borkowski, K., Risis, S., Pærregaard, S. I., Søgaard, I., Poupeau, A. A. G., Poulsen, M., Ma, Tao, Sina, C., Kiens, Bente, Madsen, L., Kristiansen, Karsten & Treebak, Jonas Thue, 2016, In: Metabolism. 65, 12, p. 1706-1719 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    81. Published

      Effect of a long-term high-protein diet on survival, obesity development, and gut microbiota in mice

      Kiilerich, P., Myrmel, L. S., Fjære, E., Hao, Q., Hugenholtz, F., Sonne, S. B., Derrien, M., Pedersen, L. M., Petersen, R. K., Mortensen, A., Licht, T. R., Rømer, M. U. K., Vogel, U. B., Waagbo, L. J., Giallourou, N., Feng, Q., Xiao, L., Liu, C., Liaset, B., Kleerebezem, M. & 3 others, Wang, J., Madsen, L. & Kristiansen, Karsten, 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 310, 11, p. E886-E899 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    82. Published

      FFAR4 (GPR120) signaling is not required for anti-inflammatory and insulin-sensitizing effects of omega-3 fatty acids

      Pærregaard, S. I., Andersen, M. A., Serup, A. K. L., Ma, Tao, Kiens, Bente, Madsen, L., Kristiansen, Karsten & Jensen, Benjamin Anderschou Holbech, 2016, In: Mediators of Inflammation. 2016, 12 p., 1536047.

      Research output: Contribution to journal › Journal article › Research › peer-review

    83. Published

      Human gut microbes impact host serum metabolome and insulin sensitivity

      Pedersen, H. K., Gudmundsdottir, V., Nielsen, H. B., Hyotylainen, T., Nielsen, T., Jensen, B. A. H., Forslund, K., Hildebrand, F., Prifti, E., Falony, G., Le Chatelier, E., Levenez, F., Doré, J., Mattila, I., Plichta, D. R., Pöhö, P., Hellgren, L. I., Arumugam, M., Sunagawa, S., Vieira-Silva, S. & 14 others, Jørgensen, T., Holm, J. B., Trošt, K., Kristiansen, Karsten, Brix, Susanne, Raes, J., Wang, J., Hansen, Torben, Bork, P., Brunak, Søren, Oresic, M., Ehrlich, S. D., Pedersen, Oluf Borbye & MetaHIT Consortium, M. C., 2016, In: Nature. 535, 7612, p. 376-381 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    84. Published

      IRF8 transcription-factor-dependent classical dendritic cells are essential for intestinal T cell homeostasis

      Luda, K. M., Joeris, T., Persson, E. K., Rivollier, A. M. C., Demiri, M., Sitnik, K. M., Pool, L., Holm, J. B., Melo-Gonzalez, F., Richter, L., Lambrecht, B. N., Kristiansen, Karsten, Travis, M. A., Svensson-Frej, M., Kotarsky, K. & Agace, W. W., 2016, In: Immunity. 44, 4, p. 860-874 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    85. Published

      Importance of the fat content within the cheese-matrix for blood lipid profile, faecal fat excretion, and gut microbiome in growing pigs

      Thorning, T. K., Raben, Anne, Bendsen, N. T., Jørgensen, H. J. H., Kiilerich, P., Ardö, Ylva Margareta, Lorenzen, J. K., Kristiansen, Karsten & Astrup, A., 2016, In: International Dairy Journal. 61, p. 67-75 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    86. Published

      Integrated metabolomics and metagenomics analysis of plasma and urine identified microbial metabolites associated with coronary heart disease

      Feng, Q., Liu, Z., Zhong, S., Li, R., Xia, H., Jie, Z., Wen, B., Chen, X., Yan, W., Fan, Y., Guo, Z., Meng, N., Chen, J., Yu, X., Zhang, Z., Kristiansen, Karsten, Wang, J., Xu, X., He, K. & Li, G., 2016, In: Scientific Reports. 6, 14 p., 22525 .

      Research output: Contribution to journal › Journal article › Research › peer-review

    87. Published

      Intrauterine exposure to paracetamol and aniline impairs female reproductive development by reducing follicle reserves and fertility

      Holm, J. B., Mazaud-Guittot, S., Danneskiold-Samsøe, Niels Banhos, Chalmey, C., Jensen, Benjamin Anderschou Holbech, Nørregård, M. M., Hansen, C. H., Styrishave, Bjarne, Svingen, T., Vinggaard, A. M., Koch, H. M., Bowles, J., Koopman, P., Jégou, B., Kristiansen, Karsten & Kristensen, D. M., 2016, In: Toxicological Sciences. 150, 1, p. 178-189 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    88. Published

      Long-term consumption of an obesogenic high fat diet prior to ischemia-reperfusion mediates cardioprotection via Epac1-dependent signaling

      Edland, F., Wergeland, A., Kopperud, R., Åsrud, K. S., Hoivik, E. A., Witsø, S. L., Æsøy, R., Madsen, L., Kristiansen, Karsten, Bakke, M., Døskeland, S. O. & Jonassen, A. K., 2016, In: Nutrition & Metabolism. 13, 11 p., 87.

      Research output: Contribution to journal › Journal article › Research › peer-review

    89. Published

      MDM2 facilitates adipocyte differentiation through CRTC-mediated activation of STAT3

      Hallenborg, P., Siersbæk, M., Barrio-Hernandez, I., Nielsen, R., Kristiansen, Karsten, Mandrup, S., Grøntved, L. & Blagoev, B., 2016, In: Cell Death & Disease. 7, 12 p., e2289.

      Research output: Contribution to journal › Journal article › Research › peer-review

    90. Published

      Macronutrient composition determines accumulation of persistent organic pollutants from dietary exposure in adipose tissue of mice

      Myrmel, L. S., Fjære, E., Midtbø, L. K., Bernhard, A., Petersen, R. K., Sonne, Si Brask, Mortensen, A., Hao, Q., Brattelid, T., Liaset, B., Kristiansen, Karsten & Madsen, L., 2016, In: Journal of Nutritional Biochemistry. 27, p. 307-316 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    91. Published

      Marine fatty acids aggravate hepatotoxicity of α-HBCD in juvenile female BALB/c mice

      Bernhard, A., Berntssen, M. H. G., Lundebye, A., Alvheim, A. R., Myrmel, L. S., Fjære, E., Torstensen, B. E., Kristiansen, Karsten, Madsen, L., Brattelid, T. & Rasinger, J. D., 2016, In: Food and Chemical Toxicology. 97, p. 411-423 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    92. Published

      Novel Y-chromosomal microdeletions associated with non-obstructive azoospermia uncovered by high throughput sequencing of sequence-tagged sites (STSs)

      Liu, X., Li, Z., Su, Z., Zhang, J., Li, H., Xie, J., Xu, H., Jiang, T., Luo, L., Zhang, R., Zeng, X., Xu, H., Huang, Y., Mou, L., Hu, J., Qian, W., Zeng, Y., Zhang, X., Xiong, C., Yang, H. & 4 others, Kristiansen, Karsten, Cai, Z., Wang, J. & Gui, Y., 2016, In: Scientific Reports. 6, 12 p., 21831 .

      Research output: Contribution to journal › Journal article › Research › peer-review

    93. Published

      Shotgun metagenomics of 250 adult twins reveals genetic and environmental impacts on the gut microbiome

      Xie, H., Guo, R., Zhong, H., Feng, Q., Lan, Z., Qin, B., Ward, K. J., Jackson, M. A., Xia, Y., Chen, X., Chen, B., Xia, H., Xu, C., Li, F., Xu, X., Al-Aama, J. Y., Yang, H., Wang, J., Kristiansen, K., Wang, J. & 5 others, Steves, C. J., Bell, J. T., Li, J., Spector, T. D. & Jia, H., 2016, In: Cell Systems. 3, 6, p. 572-584.e3 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    94. Published

      Systematic comparative evaluation of methods for investigating the TCRβ repertoire

      Liu, X., Zhang, W., Zeng, X., Zhang, R., Du, Y., Hong, X., Cao, H., Su, Z., Wang, C., Wu, J., Nie, C., Xu, X. & Kristiansen, Karsten, 2016, In: P L o S One. 11, 3, 18 p., e0152464.

      Research output: Contribution to journal › Journal article › Research › peer-review

    95. Published

      The Mouse Intestinal Bacterial Collection (miBC) provides host-specific insight into cultured diversity and functional potential of the gut microbiota

      Lagkouvardos, I., Pukall, R., Abt, B., Foesel, B. U., Meier-Kolthoff, J. P., Kumar, N., Bresciani, A., Martínez, I., Just, S., Ziegler, C., Brugiroux, S., Garzetti, D., Wenning, M., Bui, T. P. N., Wang, J., Hugenholtz, F., Plugge, C. M., Peterson, D. A., Hornef, M. W., Baines, J. F. & 8 others, Smidt, H., Walter, J., Kristiansen, Karsten, Nielsen, H. B., Haller, D., Overmann, J., Stecher, B. & Clavel, T., 2016, In: Nature Microbiology. 1, 15 p., 16131.

      Research output: Contribution to journal › Journal article › Research › peer-review

    96. Published

      The elusive endogenous adipogenic PPARγ agonists: lining up the suspects

      Hallenborg, P., Petersen, R. K., Kouskoumvekaki, I., Newman, J. W., Madsen, L. & Kristiansen, Karsten, 2016, In: Progress in Lipid Research. 61, p. 149-162 14 p.

      Research output: Contribution to journal › Review › Research › peer-review

    97. Published

      The protein source determines the potential of high protein diets to attenuate obesity development in C57BL/6J mice

      Aune, U. L., Myrmel, L. S., Fjære, E., Rønnevik, A. K., Bjelland, S., Fauske, K. R., Holm, J. B., Basse, A. L., Hansen, Jacob B., Liaset, B., Kristiansen, Karsten & Madsen, L., 2016, In: Adipocytes. 5, 2, p. 196-211 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    98. Published

      p53 regulates expression of uncoupling protein 1 through binding and repression of PPARγ coactivator-1α

      Hallenborg, P., Fjære, E., Liaset, B., Petersen, R. K., Murano, I., Sonne, Si Brask, Falkerslev, M., Winther, Sally, Jensen, Benjamin Anderschou Holbech, Ma, Tao, Hansen, Jacob B., Cinti, S., Blagoev, B., Madsen, L. & Kristiansen, Karsten, 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 310, 2, p. E116-128 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    99. Published

      Diet-induced obesity, energy metabolism and gut microbiota in C57BL/6J mice fed Western diets based on lean seafood or lean meat mixtures

      Holm, J. B., Rønnevik, A. K., Tastesen, H. S., Fjære, E., Fauske, K. R., Aune, U. L., Madsen, L., Kristiansen, Karsten & Liaset, B., May 2016, In: The Journal of Nutritional Biochemistry. 31, p. 127-136 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    100. Published

      Intake of a Western diet containing cod instead of pork alters fatty acid composition in tissue phospholipids and attenuates obesity and hepatic lipid accumulation in mice

      Aune, U. L., Fauske, K. R., Kuda, O., Fjære, E., Myrmel, L. S., Norberg, N., Frøyland, L., Graff, I. E., Liaset, B., Kristiansen, Karsten, Kopecky, J. & Madsen, L., Jul 2016, In: Journal of Nutritional Biochemistry. 33, p. 119-127 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    101. 2017
    102. Published

      Analysis of 62 hybrid assembled human Y chromosomes exposes rapid structural changes and high rates of gene conversion

      Skov, L., Schierup, M. H., Danish Pan Genome Consortium, D. P. G. C., Sørensen, L. M., Petersen, Bent, Sibbesen, Jonas Andreas, Liu, S., Belling, K. G., Have, C. T., Bork-Jensen, J., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Rasmussen, Simon, Kristiansen, Karsten & Brunak, Søren, 2017, In: PLOS Genetics. 13, 8, p. e1006834

      Research output: Contribution to journal › Journal article › Research › peer-review

    103. Published

      Assessment of the cPAS-based BGISEQ-500 platform for metagenomic sequencing

      Fang, Chao, Zhong, H., Lin, Y., Chen, B., Han, Mo, Ren, H., Lu, H., Luber, J. M., Xia, M., Li, W., Stein, S., Xu, X., Zhang, W., Drmanac, R., Wang, J., Yang, H., Hammarström, L., Kostic, A. D., Kristiansen, Karsten & Li, J., 2017, In: GigaScience. 7, 3, p. 1-8 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    104. Published

      Mammary alveolar epithelial cells convert to brown adipocytes in post-lactating mice

      Giordano, A., Perugini, J., Kristensen, D. M., Sartini, L., Frontini, A., Kajimura, S., Kristiansen, Karsten & Cinti, S., 2017, In: Journal of Cellular Physiology. 232, 11, p. 2923-2928 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    105. Published

      Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer

      Yu, J., Feng, Q., Wong, S. H., Zhang, D., Liang, Q. Y., Qin, Y., Tang, L., Zhao, H., Stenvang, J., Li, Y., Wang, X., Xu, X., Chen, N., Wu, W. K. K., Al-Aama, J., Nielsen, H. J., Kiilerich, P., Jensen, B. A. H., Yau, T. O., Lan, Z. & 19 others, Jia, H., Li, J., Xiao, L., Lam, T. Y. T., Ng, S. C., Cheng, A. S., Wong, V. W., Chan, F. K. L., Xu, X., Yang, H., Madsen, L., Datz, C., Tilg, H., Wang, J., Brünner, N., Kristiansen, Karsten, Arumugam, Mani, Sung, J. J. & Wang, J., 2017, In: Gut. 66, p. 70-78 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    106. Published

      Obesity is associated with depot-specific alterations in adipocyte DNA methylation and gene expression

      Sonne, Si Brask, Yadav, R., Yin, G., Dalgaard, M. D., Myrmel, L. S., Gupta, R., Wang, J., Madsen, L., Kajimura, S. & Kristiansen, Karsten, 2017, In: Adipocyte. 6, 2, p. 124-133 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 6489714