Competing to destroy: a fight between two RNA-degradation systems
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Competing to destroy: a fight between two RNA-degradation systems. / Thon, Genevieve.
In: Nature Structural and Molecular Biology, Vol. 15, No. 10, 2008, p. 1001-2.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Competing to destroy: a fight between two RNA-degradation systems
AU - Thon, Genevieve
N1 - KEYWORDS: Protein Binding; RNA Stability; RNA, Small Interfering; Schizosaccharomyces
PY - 2008
Y1 - 2008
N2 - The Argonaute-1 (Ago1) protein bound to small interfering RNAs (siRNAs) directs heterochromatin formation in fission yeast. A high-throughput sequencing approach reveals that the composition of the Ago1-bound siRNA population is sensitive to the noncanonical poly(A) polymerase Cid14, indicating that the RNA-interference and Cid14-TRAMP RNA-degradation pathways compete for substrates in fission yeast.
AB - The Argonaute-1 (Ago1) protein bound to small interfering RNAs (siRNAs) directs heterochromatin formation in fission yeast. A high-throughput sequencing approach reveals that the composition of the Ago1-bound siRNA population is sensitive to the noncanonical poly(A) polymerase Cid14, indicating that the RNA-interference and Cid14-TRAMP RNA-degradation pathways compete for substrates in fission yeast.
U2 - 10.1038/nsmb1008-1001
DO - 10.1038/nsmb1008-1001
M3 - Journal article
C2 - 18836493
VL - 15
SP - 1001
EP - 1002
JO - Nature Structural and Molecular Biology
JF - Nature Structural and Molecular Biology
SN - 1545-9993
IS - 10
ER -
ID: 9179081