Standard
Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects : validation and extension of genome-wide association studies. / Grarup, Niels; Rose, Chrisian S.; Andersson, Ehm A.; Andersen, Gitte; Nielsen, Arne L.; Albrechtsen, Anders; Clausen, Jesper O.; Rasmussen, Signe S.; Jørgensen, Torben; Sandbæk, Annelli; Lauritzen, Torsten; Schmitz, Ole; Hansen, Torben; Pedersen, Oluf.
In:
Diabetes, Vol. 56, No. 12, 2007, p. 3105-3111.
Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
Grarup, N, Rose, CS, Andersson, EA, Andersen, G, Nielsen, AL
, Albrechtsen, A, Clausen, JO, Rasmussen, SS, Jørgensen, T, Sandbæk, A, Lauritzen, T, Schmitz, O, Hansen, T & Pedersen, O 2007, '
Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies',
Diabetes, vol. 56, no. 12, pp. 3105-3111.
https://doi.org/10.2337/db07-0856
APA
Grarup, N., Rose, C. S., Andersson, E. A., Andersen, G., Nielsen, A. L.
, Albrechtsen, A., Clausen, J. O., Rasmussen, S. S., Jørgensen, T., Sandbæk, A., Lauritzen, T., Schmitz, O., Hansen, T., & Pedersen, O. (2007).
Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies.
Diabetes,
56(12), 3105-3111.
https://doi.org/10.2337/db07-0856
Vancouver
Grarup N, Rose CS, Andersson EA, Andersen G, Nielsen AL
, Albrechtsen A et al.
Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies.
Diabetes. 2007;56(12):3105-3111.
https://doi.org/10.2337/db07-0856
Author
Grarup, Niels ; Rose, Chrisian S. ; Andersson, Ehm A. ; Andersen, Gitte ; Nielsen, Arne L. ; Albrechtsen, Anders ; Clausen, Jesper O. ; Rasmussen, Signe S. ; Jørgensen, Torben ; Sandbæk, Annelli ; Lauritzen, Torsten ; Schmitz, Ole ; Hansen, Torben ; Pedersen, Oluf. / Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects : validation and extension of genome-wide association studies. In: Diabetes. 2007 ; Vol. 56, No. 12. pp. 3105-3111.
Bibtex
@article{557a419250cc4c5b92b7fc28147ebefe,
title = "Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies",
abstract = "In the present study, we aimed to validate the type 2 diabetes susceptibility alleles identified in six recent genome-wide association studies in the HHEX/KIF11/IDE (rs1111875), CDKN2A/B (rs10811661), and IGF2BP2 (rs4402960) loci, as well as the intergenic rs9300039 variant. Furthermore, we aimed to characterize quantitative metabolic risk phenotypes of the four variants.",
keywords = "Adult, Cohort Studies, Cyclin-Dependent Kinase Inhibitor p15, Cyclin-Dependent Kinase Inhibitor p16, Denmark, Diabetes Mellitus, Type 2, European Continental Ancestry Group, Genetic Predisposition to Disease, Genetic Variation, Genome, Human, Glucose Intolerance, Homeodomain Proteins, Humans, Insulin, Insulin-Like Growth Factor Binding Protein 2, Introns, Middle Aged, Reference Values, Reproducibility of Results, Transcription Factors",
author = "Niels Grarup and Rose, {Chrisian S.} and Andersson, {Ehm A.} and Gitte Andersen and Nielsen, {Arne L.} and Anders Albrechtsen and Clausen, {Jesper O.} and Rasmussen, {Signe S.} and Torben J{\o}rgensen and Annelli Sandb{\ae}k and Torsten Lauritzen and Ole Schmitz and Torben Hansen and Oluf Pedersen",
year = "2007",
doi = "10.2337/db07-0856",
language = "English",
volume = "56",
pages = "3105--3111",
journal = "Diabetes",
issn = "0012-1797",
publisher = "American Diabetes Association",
number = "12",
}
RIS
TY - JOUR
T1 - Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects
T2 - validation and extension of genome-wide association studies
AU - Grarup, Niels
AU - Rose, Chrisian S.
AU - Andersson, Ehm A.
AU - Andersen, Gitte
AU - Nielsen, Arne L.
AU - Albrechtsen, Anders
AU - Clausen, Jesper O.
AU - Rasmussen, Signe S.
AU - Jørgensen, Torben
AU - Sandbæk, Annelli
AU - Lauritzen, Torsten
AU - Schmitz, Ole
AU - Hansen, Torben
AU - Pedersen, Oluf
PY - 2007
Y1 - 2007
N2 - In the present study, we aimed to validate the type 2 diabetes susceptibility alleles identified in six recent genome-wide association studies in the HHEX/KIF11/IDE (rs1111875), CDKN2A/B (rs10811661), and IGF2BP2 (rs4402960) loci, as well as the intergenic rs9300039 variant. Furthermore, we aimed to characterize quantitative metabolic risk phenotypes of the four variants.
AB - In the present study, we aimed to validate the type 2 diabetes susceptibility alleles identified in six recent genome-wide association studies in the HHEX/KIF11/IDE (rs1111875), CDKN2A/B (rs10811661), and IGF2BP2 (rs4402960) loci, as well as the intergenic rs9300039 variant. Furthermore, we aimed to characterize quantitative metabolic risk phenotypes of the four variants.
KW - Adult
KW - Cohort Studies
KW - Cyclin-Dependent Kinase Inhibitor p15
KW - Cyclin-Dependent Kinase Inhibitor p16
KW - Denmark
KW - Diabetes Mellitus, Type 2
KW - European Continental Ancestry Group
KW - Genetic Predisposition to Disease
KW - Genetic Variation
KW - Genome, Human
KW - Glucose Intolerance
KW - Homeodomain Proteins
KW - Humans
KW - Insulin
KW - Insulin-Like Growth Factor Binding Protein 2
KW - Introns
KW - Middle Aged
KW - Reference Values
KW - Reproducibility of Results
KW - Transcription Factors
U2 - 10.2337/db07-0856
DO - 10.2337/db07-0856
M3 - Journal article
C2 - 17827400
VL - 56
SP - 3105
EP - 3111
JO - Diabetes
JF - Diabetes
SN - 0012-1797
IS - 12
ER -
