A- or C-chromosomes, does it matter for the transfer of transgenes from Brassica napus

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Standard

A- or C-chromosomes, does it matter for the transfer of transgenes from Brassica napus. / Tomiuk, J.; Hauser, Thure Pavlo; Jørgensen, R.B.

I: Theoretical and Applied Genetics, Bind 100, Nr. 5, 2000, s. 750-754.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Tomiuk, J, Hauser, TP & Jørgensen, RB 2000, 'A- or C-chromosomes, does it matter for the transfer of transgenes from Brassica napus', Theoretical and Applied Genetics, bind 100, nr. 5, s. 750-754. https://doi.org/10.1007/s001220051348

APA

Tomiuk, J., Hauser, T. P., & Jørgensen, R. B. (2000). A- or C-chromosomes, does it matter for the transfer of transgenes from Brassica napus. Theoretical and Applied Genetics, 100(5), 750-754. https://doi.org/10.1007/s001220051348

Vancouver

Tomiuk J, Hauser TP, Jørgensen RB. A- or C-chromosomes, does it matter for the transfer of transgenes from Brassica napus. Theoretical and Applied Genetics. 2000;100(5):750-754. https://doi.org/10.1007/s001220051348

Author

Tomiuk, J. ; Hauser, Thure Pavlo ; Jørgensen, R.B. / A- or C-chromosomes, does it matter for the transfer of transgenes from Brassica napus. I: Theoretical and Applied Genetics. 2000 ; Bind 100, Nr. 5. s. 750-754.

Bibtex

@article{43b26e9074c811dbbee902004c4f4f50,
title = "A- or C-chromosomes, does it matter for the transfer of transgenes from Brassica napus",
abstract = "Introgression of genes from allotetraploid Brassica napus into its diploid wild relative B. rapa is generally considered to be inevitable. As a means to minimize a potential ecological risk in environments where B. rapa is growing, the insertion of transgenes into chromosome regions of B. napus with a very low probability of transfer to backcross generations with B. rapa has been proposed. Recently, the progeny of four backcross generations between transgenic herbicide-tolerant B. napus and B. rapa was studied in selection experiments (Metz et al. 1997). The rapid decrease in the frequency of herbicide-tolerant plants was explained by selection against the C-chromosomes of B. napus in favor of the homeologous A-chromosomes. Obviously, such C-chromosomes could be potential candidates as safe integration sites for transgenes. We considered these safety aspects using a simple population genetic model. Theory and experiments, however, do not favor the chromosomes of B. napus as safe candidates with respect to the introgression of transgenes into wild populations of B. rapa.",
author = "J. Tomiuk and Hauser, {Thure Pavlo} and R.B. J{\o}rgensen",
note = "Key words Safe integration - Chromosome variation - Oilseed rape - Gene transfer - Risk assessment, Brassica rapa",
year = "2000",
doi = "10.1007/s001220051348",
language = "English",
volume = "100",
pages = "750--754",
journal = "Theoretical And Applied Genetics",
issn = "0040-5752",
publisher = "Springer",
number = "5",

}

RIS

TY - JOUR

T1 - A- or C-chromosomes, does it matter for the transfer of transgenes from Brassica napus

AU - Tomiuk, J.

AU - Hauser, Thure Pavlo

AU - Jørgensen, R.B.

N1 - Key words Safe integration - Chromosome variation - Oilseed rape - Gene transfer - Risk assessment, Brassica rapa

PY - 2000

Y1 - 2000

N2 - Introgression of genes from allotetraploid Brassica napus into its diploid wild relative B. rapa is generally considered to be inevitable. As a means to minimize a potential ecological risk in environments where B. rapa is growing, the insertion of transgenes into chromosome regions of B. napus with a very low probability of transfer to backcross generations with B. rapa has been proposed. Recently, the progeny of four backcross generations between transgenic herbicide-tolerant B. napus and B. rapa was studied in selection experiments (Metz et al. 1997). The rapid decrease in the frequency of herbicide-tolerant plants was explained by selection against the C-chromosomes of B. napus in favor of the homeologous A-chromosomes. Obviously, such C-chromosomes could be potential candidates as safe integration sites for transgenes. We considered these safety aspects using a simple population genetic model. Theory and experiments, however, do not favor the chromosomes of B. napus as safe candidates with respect to the introgression of transgenes into wild populations of B. rapa.

AB - Introgression of genes from allotetraploid Brassica napus into its diploid wild relative B. rapa is generally considered to be inevitable. As a means to minimize a potential ecological risk in environments where B. rapa is growing, the insertion of transgenes into chromosome regions of B. napus with a very low probability of transfer to backcross generations with B. rapa has been proposed. Recently, the progeny of four backcross generations between transgenic herbicide-tolerant B. napus and B. rapa was studied in selection experiments (Metz et al. 1997). The rapid decrease in the frequency of herbicide-tolerant plants was explained by selection against the C-chromosomes of B. napus in favor of the homeologous A-chromosomes. Obviously, such C-chromosomes could be potential candidates as safe integration sites for transgenes. We considered these safety aspects using a simple population genetic model. Theory and experiments, however, do not favor the chromosomes of B. napus as safe candidates with respect to the introgression of transgenes into wild populations of B. rapa.

U2 - 10.1007/s001220051348

DO - 10.1007/s001220051348

M3 - Journal article

VL - 100

SP - 750

EP - 754

JO - Theoretical And Applied Genetics

JF - Theoretical And Applied Genetics

SN - 0040-5752

IS - 5

ER -

ID: 181164