Molecular Detection and Characterization of Intestinal and Blood Parasites in Wild Chimpanzees (Pan troglodytes verus) in Senegal
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Molecular Detection and Characterization of Intestinal and Blood Parasites in Wild Chimpanzees (Pan troglodytes verus) in Senegal. / Köster, Pamela C.; Renelies‐hamilton, Justinn; Dotras, Laia; Llana, Manuel; Vinagre‐izquierdo, Celia; Prakas, Petras; Sneideris, Donatas; Dashti, Alejandro; Bailo, Begoña; Lanza, Marta; Jiménez‐Mejías, Alejandra; Muñoz‐García, Carlota; Muadica, Aly S.; González‐Barrio, David; Rubio, José M.; Fuentes, Isabel; Ponce‐Gordo, Francisco; Calero‐Bernal, Rafael; Carmena, David.
In: Animals, Vol. 11, No. 11, 3291, 2021.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Molecular Detection and Characterization of Intestinal and Blood Parasites in Wild Chimpanzees (Pan troglodytes verus) in Senegal
AU - Köster, Pamela C.
AU - Renelies‐hamilton, Justinn
AU - Dotras, Laia
AU - Llana, Manuel
AU - Vinagre‐izquierdo, Celia
AU - Prakas, Petras
AU - Sneideris, Donatas
AU - Dashti, Alejandro
AU - Bailo, Begoña
AU - Lanza, Marta
AU - Jiménez‐Mejías, Alejandra
AU - Muñoz‐García, Carlota
AU - Muadica, Aly S.
AU - González‐Barrio, David
AU - Rubio, José M.
AU - Fuentes, Isabel
AU - Ponce‐Gordo, Francisco
AU - Calero‐Bernal, Rafael
AU - Carmena, David
N1 - Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021
Y1 - 2021
N2 - Wild chimpanzee populations in West Africa (Pan troglodytes verus) have dramatically decreased as a direct consequence of anthropogenic activities and infectious diseases. Little information is currently available on the epidemiology, pathogenic significance, and zoonotic potential of protist species in wild chimpanzees. This study investigates the occurrence and genetic diversity of intestinal and blood protists as well as filariae in faecal samples (n = 234) from wild chimpanzees in the Dindefelo Community Nature Reserve, Senegal. PCR‐based results revealed the presence of intestinal potential pathogens (Sarcocystis spp.: 11.5%; Giardia duodenalis: 2.1%; Cryptosporidium hominis: 0.9%), protist of uncertain pathogenicity (Blastocystis sp.: 5.6%), and commensal species (Entamoeba dispar: 18.4%; Troglodytella abrassarti: 5.6%). Entamoeba histolytica, Enterocytozoon bieneusi, and Balantioides coli were undetected. Blood protists including Plasmodium malariae (0.4%), Trypanosoma brucei (1.3%), and Mansonella perstans (9.8%) were also identified. Sanger sequencing analyses revealed host‐adapted genetic variants within Blastocystis, but other parasitic pathogens (C. hominis, P. malariae, T. brucei, M. perstans) have zoonotic potential, suggesting that cross‐species transmission between wild chimpanzees and humans is possible in areas where both species overlap. Additionally, we explored potential interactions between intestinal/blood protist species and seasonality and climate variables. Chimpanzees seem to play a more complex role on the epidemiology of pathogenic and commensal protist and nematode species than initially anticipated.
AB - Wild chimpanzee populations in West Africa (Pan troglodytes verus) have dramatically decreased as a direct consequence of anthropogenic activities and infectious diseases. Little information is currently available on the epidemiology, pathogenic significance, and zoonotic potential of protist species in wild chimpanzees. This study investigates the occurrence and genetic diversity of intestinal and blood protists as well as filariae in faecal samples (n = 234) from wild chimpanzees in the Dindefelo Community Nature Reserve, Senegal. PCR‐based results revealed the presence of intestinal potential pathogens (Sarcocystis spp.: 11.5%; Giardia duodenalis: 2.1%; Cryptosporidium hominis: 0.9%), protist of uncertain pathogenicity (Blastocystis sp.: 5.6%), and commensal species (Entamoeba dispar: 18.4%; Troglodytella abrassarti: 5.6%). Entamoeba histolytica, Enterocytozoon bieneusi, and Balantioides coli were undetected. Blood protists including Plasmodium malariae (0.4%), Trypanosoma brucei (1.3%), and Mansonella perstans (9.8%) were also identified. Sanger sequencing analyses revealed host‐adapted genetic variants within Blastocystis, but other parasitic pathogens (C. hominis, P. malariae, T. brucei, M. perstans) have zoonotic potential, suggesting that cross‐species transmission between wild chimpanzees and humans is possible in areas where both species overlap. Additionally, we explored potential interactions between intestinal/blood protist species and seasonality and climate variables. Chimpanzees seem to play a more complex role on the epidemiology of pathogenic and commensal protist and nematode species than initially anticipated.
KW - Conservation
KW - Endangered
KW - Epidemiology
KW - Genotyping
KW - Non‐human primates
KW - PCR
KW - Protists
KW - Seasonality
KW - Zoonoses
U2 - 10.3390/ani11113291
DO - 10.3390/ani11113291
M3 - Journal article
C2 - 34828022
AN - SCOPUS:85119079924
VL - 11
JO - Animals
JF - Animals
SN - 2076-2615
IS - 11
M1 - 3291
ER -
ID: 287070249