Computational and RNA Biology

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  1. 2012
  2. Published

    mRNA pseudoknot structures can act as ribosomal roadblocks

    Hansen, J. T., Oddershede, L. B. & Sørensen, Michael Askvad, 2012, In: Nucleic Acids Research. 40, 1, p. 303-313 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    An efficient null model for conformational fluctuations in proteins

    Harder, T. P., Bottaro, S., Boomsma, Wouter, Olsson, S., Ferkinghoff-Borg, J. & Hamelryck, Thomas Wim, 2012, In: Structure. 20, 6, p. 1028-1039 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Fast large-scale clustering of protein structures using Gauss integrals

    Harder, T. P., Borg, M., Boomsma, Wouter, Røgen, P. & Hamelryck, Thomas Wim, 2012, In: Bioinformatics. 28, 4, p. 510-515 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Cape buffalo mitogenomics reveals a holocene shift in the African human-megafauna dynamics

    Heller, Rasmus, Brüniche-Olsen, A. & Siegismund, Hans Redlef, 2012, In: Molecular Ecology. 21, 16, p. 3947-3959 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Predictive active set selection methods for Gaussian processes

    Henao, R. & Winther, Ole, 2012, In: Neurocomputing. 80, p. 10-18 9 p.

    Research output: Contribution to journal › Conference article › Research › peer-review

  7. Published

    Extensive X-linked adaptive evolution in central chimpanzees

    Hvilsom, C., Qian, Y., Bataillon, T., Li, Y., Mailund, T., Sallé, B., Carlsen, F., Li, R., Zheng, H., Jiang, T., Jiang, H., Jin, X., Terkelsen, K. M., Hobolth, A., Siegismund, Hans Redlef, Wang, J. & Schierup, M. H., 2012, In: Proceedings of the National Academy of Sciences USA (PNAS). 109, 6, p. 2054-2059 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    An effort to use human-based exome capture methods to analyze chimpanzee and macaque exomes

    Jin, X., He, M., Ferguson, B., Meng, Y., Ouyang, L., Ren, J., Mailund, T., Sun, F., Sun, L., Shen, J., Zhuo, M., Song, L., Wang, J., Ling, F., Zhu, Y., Hvilsom, C., Siegismund, H. R., Liu, X., Gong, Z., Ji, F. & 15 others, Wang, X., Liu, B., Zhang, Y., Hou, J., Wang, J., Zhao, H., Wang, Y., Fang, X., Zhang, G., Wang, J., Zhang, X., Schierup, M. H., Du, H., Wang, J. & Wang, X., 2012, In: P L o S One. 7, 7, 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Computational cancer biology: from carcinogenesis to metastasis

    Kaczkowski, B., 2012, Department of Biology, Faculty of Science, University of Copenhagen. 125 p.

    Research output: Book/Report › Ph.D. thesis › Research

  10. Published

    Integrative analyses reveal novel strategies in HPV11,-16 and -45 early infection

    Kaczkowski, B., Rossing, M., Andersen, D. K., Dreher, A., Morevati, M., Visser, M. A., Winther, Ole, Nielsen, Finn Cilius & Norrild, B., 2012, In: Scientific Reports. 2, p. 515

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Serotype identification and VP1 coding sequence analysis of foot-and-mouth disease viruses from outbreaks in Eastern and Northern Uganda in 2008/9

    Kasambula, L., Belsham, G., Siegismund, Hans Redlef, Muwanika, V. B., Ademun-Okurut, A. R. & Masembe, C., 2012, In: Transboundary and Emerging Diseases. 59, 4, p. 323-330 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The role of miRNAs in human papilloma virus (HPV)-associated cancers: bridging between HPV-related head and neck cancer and cervical cancer

    Lajer, C. B., Garnæs, E., Friis-Hansen, Lennart Jan, Norrild, B., Therkildsen, M. H., Glud, M., Rossing, M., Lajer, H., Svane, D., Skotte, L., Specht, Lena, von Buchwald, Christian & Nielsen, Finn Cilius, 2012, In: B J C. 106, p. 1526-1534 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Metazoan promoters: emerging characteristics and insights into transcriptional regulation

    Lenhard, B., Sandelin, Albin Gustav & Carninci, P., 2012, In: Nature Reviews. Genetics. 13, 4, p. 233-245 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    AdapterRemoval: easy cleaning of next generation sequencing reads

    Lindgreen, S., 2012, In: BMC Research Notes. 5, 337, 7 p., 337.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Comparative phylogeography of African savannah ungulates

    Lorenzen, Eline, Heller, Rasmus & Siegismund, Hans Redlef, 2012, In: Molecular Ecology. 21, 15, p. 3656-3670 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  16. Published

    DGCR8 HITS-CLIP reveals novel functions for the microprocessor

    Macias, S., Plass, M., Stajuda, A., Michlewski, G., Eyras, E. & Cáceres, J. F., 2012, In: Nature Structural and Molecular Biology. 19, 8

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Mixtures of concentrated multivariate sine distributions with applications to bioinformatics

    Mardia, K. V., Kent, J. T., Zhang, Z., Taylor, C. C. & Hamelryck, Thomas Wim, 2012, In: Journal of Applied Statistics. 39, 11, p. 2475-2492 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Statistics of bivariate von mises distributions

    Mardia, K. V. & Frellsen, J., 2012, Bayesian methods in structural bioinformatics. Hamelryck, T., Mardia, K. & Ferkinghoff-Borg, J. (eds.). Springer, p. 159-178 20 p. (Statistics for Biology and Health).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  19. Published

    RILogo: visualising RNA-RNA interactions

    Menzel, K. P., Seemann, Ernst Stefan & Gorodkin, Jan, 2012, In: Bioinformatics. 28, 19, p. 2523-2526 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Genetic diversity in the desert warthog (Phacochoerus aethiopicus delameri) population of eastern Africa

    Muwanika, V. B., Kock, R., Masembe, C. & Siegismund, Hans Redlef, 2012, In: South African Journal of Wildlife Research. 42, 1, p. 54-59 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    SNP calling, genotype calling, and sample allele frequency estimation from new-generation sequencing data

    Nielsen, Rasmus, Korneliussen, Thorfinn Sand, Albrechtsen, Anders, Li, Y. & Wang, J., 2012, In: PLoS ONE. 7, 7, 11 p., e37558.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Current and emerging approaches to define intestinal epithelium-specific transcriptional networks

    Olsen, A. K., Boyd, M., Danielsen, E. T. & Troelsen, J. T., Feb 2012, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 302, 3, p. G277-86

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Significance of calcium binding, tyrosine phosphorylation, and lysine trimethylation for the essential function of calmodulin in vertebrate cells analyzed in a novel gene replacement system

    Panina, S., Stephan, A., la Cour, J. M., Jacobsen, K., Kallerup, L. K., Bumbuleviciute, R., Knudsen, K. V. K., Sanchez-Gonzalez, P., Villalobo, A., Olesen, U. H. & Berchtold, Martin Werner, 2012, In: Journal of Biological Chemistry. 287, 22, p. 18173-18181 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Systematic identification of long noncoding RNAs expressed during zebrafish embryogenesis

    Pauli, A., Valen, E., Lin, M. F., Garber, M., Vastenhouw, N. L., Levin, J. Z., Fan, L., Sandelin, Albin Gustav, Rinn, J. L., Regev, A. & Schier, A. F., 2012, In: Genome Research. 22, p. 577-591 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Biological systems on a small scale

    Pedersen, L., 2012, Center for Ice & Climate: Faculty of Science, University of Copenhagen. 184 p.

    Research output: Book/Report › Ph.D. thesis › Research

  26. Published

    Prey diversity is affected by climate and differs between age classes in the Red-backed Shrike (Lanius collurio)

    Pedersen, L., Geertsma, M. & Tøttrup, Anders P., 2012, In: Ornis Fennica. 89, 2, p. 99-108 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Down-regulation of microRNAs controlling tumourigenic factors in follicular thyroid carcinoma

    Rossing, M., Helweg-Larsen, R. B., Henao Giraldo, R., Winther, Ole, Vikeså, J., Niazi, O., Godballe, C., Krogdahl, A., Glud, M., Sørensen, C. H., Kiss, K., Bennedbæk, F. N. & Nielsen, Finn Cilius, 2012, In: Journal of Molecular Endocrinology. 48, 1, p. 11-23 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Cross-species ChIP-seq studies provide insights into regulatory strategies of PPAR¿ in adipocytes

    Schmidt, S. F., Jørgensen, M., Sandelin, Albin Gustav & Mandrup, S., 2012, In: Transcription. 3, 1, p. 19-24 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Improving ancient DNA read mapping against modern reference genomes

    Schubert, Mikkel, Ginolhac, A., Lindgreen, S., Thompson, J. F., Al-Rasheid, K. A. S., Willerslev, Eske, Krogh, Anders & Orlando, L. A. A., 2012, In: BMC Genomics. 13, 15 p., 178.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Association testing for next-generation sequencing data using score statistics

    Skotte, L., Korneliussen, Thorfinn Sand & Albrechtsen, Anders, 2012, In: Genetic Epidemiology. 36, 5, p. 430-437 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Interaction of antidepressants with the serotonin and norepinephrine transporters: mutational studies of the S1 substrate binding pocket

    Sørensen, L., Andersen, J., Thomsen, M., Hansen, S. M. R., Zhao, X., Sandelin, Albin Gustav, Strømgaard, Kristian & Kristensen, Anders Skov, 2012, In: The Journal of Biological Chemistry. 287, 52, p. 43694-43707 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Interaction of antidepressants with the serotonin and norepinephrine transporters: mutational studies of the S1 substrate binding pocket

    Sørensen, L., Andersen, J., Thomsen, M., Hansen, S. M. R., Zhao, X., Sandelin, Albin Gustav, Strømgaard, Kristian & Kristensen, Anders Skov, 2012, In: Journal of Biological Chemistry. 287, p. 43694-43707 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Mediator regulates non-coding RNA transcription at fission yeast centromeres

    Thorsen, M., Hansen, H., Venturi, M., Holmberg, Steen & Thon, Genevieve, 2012, In: Epigenetics & Chromatin. 5, p. 1-10 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    MicroRNAs and Their Antagonists as Novel Therapeutics

    Vinther, Jeppe, Rukov, J. & Shomron, N., 2012, From Nucleic Acids Sequences to Molecular Medicine. Erdmann, V. A. & Barciszewski, J. (eds.). Springer Publishing Company, p. 503-523 21 p. (RNA Technologies).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  35. Published

    Mammalian tissues defective in nonsense-mediated mRNA decay display highly aberrant splicing patterns

    Weischenfeldt, Joachim Lütken, Waage, J. E., Tian, G., Zhao, J., Damgaard, I., Jakobsen, J. S., Kristiansen, Karsten, Krogh, Anders, Wang, J. & Porse, Bo Torben, 2012, In: Genome Biology (Online Edition). 13, 5, 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Resequencing 50 accessions of cultivated and wild rice yields markers for identifying agronomically important genes

    Xu, X., Liu, X., Ge, S., Jensen, J. D., Hu, F., Li, X., Dong, Y., Gutenkunst, R. N., Fang, L., Huang, L., Li, J., He, W., Zhang, G., Zheng, X., Zhang, F., Li, Y., Yu, C., Kristiansen, K., Zhang, X., Wang, J. & 5 others, Wright, M., McCouch, S., Nielsen, Rasmus, Wang, J. & Wang, W., 2012, In: Nature Biotechnology. 30, 1, p. 105-111 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    GMD: measuring the distance between histograms with applications on high-throughput sequencing reads

    Zhao, X. & Sandelin, Albin Gustav, 2012, In: Bioinformatics. 28, 8, p. 1164-1165 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    On gene regulation in eukaryotes: computational approaches to decipher transcriptional regulation at genetic and epigenetic level

    Zhao, X., 2012, Department of Biology, Faculty of Science, University of Copenhagen. 170 p.

    Research output: Book/Report › Ph.D. thesis › Research

  39. 2013
  40. Published

    Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes

    Albrechtsen, A., Grarup, N., Li, Y., Sparsø, T. H., Tian, G., Cao, H., Jiang, T., Kim, S. Y., Korneliussen, T. S., Li, Q., Nie, C., Wu, R., Skotte, L., Morris, A. P., Ladenvall, C., Cauchi, S., Stancáková, A., Andersen, G., Astrup, A., Banasik, K. & 86 others, Bennett, A. J., Bolund, L., Charpentier, G., Chen, Y., Dekker, J. M., Doney, A. S. F., Dorkhan, M., Forsen, T., Frayling, T. M., Groves, C. J., Gui, Y., Hallmans, G., Hattersley, A. T., He, K., Hitman, G. A., Holmkvist, J., Huang, S., Jiang, H., Jin, X., Justesen, Johanne Marie, Kristiansen, Karsten, Kuusisto, J., Lajer, M., Lantieri, O., Li, W., Liang, H., Liao, Q., Liu, X., Ma, T., Ma, X., Manijak, M. P., Marre, M., Mokrosinski, J., Morris, A. D., Mu, B., Nielsen, A. A., Nijpels, G., Nilsson, P., Palmer, C. N. A., Rayner, N. W., Renström, F., Ribel-Madsen, R., Robertson, N., Rolandsson, O., Rossing, P., Schwartz, Thue W., Slagboom, P. E., Sterner, M., Tang, M., Tarnow, L., Tuomi, T., Van't Riet, E., van Leeuwen, N., V Varga, Tibor, Vestmar, M. A., Walker, M., Wang, B., Wang, Y., Wu, H., Xi, F., Yengo, L., Yu, C., Zhang, X., Zhang, J., Zhang, Q., Zhang, W., Zheng, H., Zhou, Y., Altshuler, D., 't Hart, L. M., Franks, P. W., Balkau, B., Froguel, P., McCarthy, M. I., Laakso, M., Groop, L., Christensen, C., Brandslund, I., Lauritzen, T., Witte, D. R., Linneberg, A., Jørgensen, T., Hansen, Torben, Wang, J., Nielsen, Rasmus & Pedersen, Oluf Borbye, 2013, In: Diabetologia. 56, 2, p. 298-310 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Probabilistic Equilibrium Sampling of Protein Structures from SAXS Data and a Coarse Grained Debye Formula

    Andreetta, C., 2013, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  42. Published

    Parallel GPGPU Evaluation of Small Angle X-ray Scattering Profiles in a Markov Chain Monte Carlo Framework

    Antonov, L. D., Andreetta, C. & Hamelryck, Thomas Wim, 2013, Biomedical Engineering Systems and Technologies. Gabriel, J., Schier, J. & Huffel, S. V. (eds.). Springer Science+Business Media, Vol. 357. p. 222-235 14 p. (Communications in Computer and Information Science).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  43. Published

    HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis

    Bagger, F. O., Rapin, N. P. J., Theilgaard-Mønch, Kim, Kaczkowski, B., Thorén, L. A. M., Jendholm, L. J., Winther, Ole & Porse, Bo Torben, 2013, In: Nucleic Acids Research. 41, Database issue, p. D1034-D1039 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Phaistos user manual

    Boomsma, Wouter, Bottaro, S., Hamelryck, Thomas Wim, Frellsen, J., Andreetta, C., Borg, M., Harder, T., Johansson, Kristoffer Enøe, Stovgaard, K. & Tian, P., 2013, 90 p.

    Research output: Book/Report › Book › Education

  45. Published

    PHAISTOS: a framework for Markov chain Monte Carlo simulation and inference of protein structure

    Boomsma, Wouter, Frellsen, J., Harder, T. P., Bottaro, S., Johansson, Kristoffer Enøe, Tian, P., Stovgaard, K., Andreetta, C., Olsson, S., Valentin, J., Antonov, L. D., Christensen, A. S., Borg, M., Jensen, Jan Halborg, Lindorff-Larsen, Kresten, Ferkinghoff-Borg, J. & Hamelryck, Thomas Wim, 2013, In: Journal of Computational Chemistry. 34, 19, p. 1697-1705 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    A short-read multiplex sequencing method for reliable, cost-effective and high-throughput genotyping in large-scale studies: [plus] Erratum

    Cao, H., Wang, Y., Zhang, W., Chai, X., Zhang, X., Chen, S., Yang, F., Zhang, C., Guo, Y., Liu, Y., Tang, Z., Chen, C., Xue, Y., Zhen, H., Xu, Y., Rao, B., Liu, T., Zhao, M., Zhang, W., Li, Y. & 6 others, Zhang, X., Tellier, L. C. A. M., Krogh, Anders, Kristiansen, Karsten, Wang, J. & Li, J., 2013, In: Human Mutation. 34, 12, p. 1715-1720 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Protein structure validation and refinement using amide proton chemical shifts derived from quantum mechanics

    Christensen, A. S., Linnet, T. E., Borg, M., Boomsma, Wouter, Lindorff-Larsen, Kresten, Hamelryck, Thomas Wim & Jensen, Jan Halborg, 2013, In: PLoS ONE. 8, 12, 10 p., e84123.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    mTOR complex 2 phosphorylates IMP1 cotranslationally to promote IGF2 production and the proliferation of mouse embryonic fibroblasts.

    Dai, N., Christiansen, Jan, Nielsen, F. & Avruch, J., 2013, In: Genes & Development. 27, 3, p. 301-312 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Combining the multicanonical ensemble with generative probabilistic models of local biomolecular structure

    Frellsen, J., Hamelryck, Thomas Wim & Ferkinghoff-Borg, J., 2013, Proceedings of the 59th World Statistics Congress of the International Statistical Institute, 2013 . Hague, p. 139-144 6 p.

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research

  50. Published

    Quantifying population genetic differentiation from next-generation sequencing data

    Fumagalli, M., Vieira, Filipe Garrett, Korneliussen, Thorfinn Sand, Linderoth, T., Huerta-Sánchez, E., Albrechtsen, Anders & Nielsen, Rasmus, Nov 2013, In: Genetics. 195, 3, p. 979-992 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Estimating inbreeding coefficients from NGS data: impact on genotype calling and allele frequency estimation

    Vieira, Filipe Garrett, Fumagalli, M., Albrechtsen, Anders & Nielsen, Rasmus, 2013, In: Genome Research. 23, p. 1852-1861 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Detection of Active Matriptase using a Biotinylated Chloromethyl Ketone Peptide

    Godiksen, S., Soendergaard, C., Friis, S., Jensen, J. K., Lange, Jette Bornholdt, Sales, K. U., Huang, M., Bugge, T. H. & Vogel, Lotte, 2013, In: P L o S One. 8, 10, 10 p., e77146.

    Research output: Contribution to journal › Journal article › Research › peer-review

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