Computational and RNA Biology

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  1. Published

    YeastFab: High-Throughput Genetic Parts Construction, Measurement, and Pathway Engineering in Yeast

    Garcia-Ruiz, E., Auxillos, Jamie Yam, Li, T., Dai, J. & Cai, Y., 1 Jan 2018, Methods in Enzymology. Scrutton, N. (ed.). Academic Press, p. 277-306 30 p. (Methods in Enzymology, Vol. 608).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  2. Published

    Langevin diffusions on the torus: estimation and applications

    García-Portugués, E., Sørensen, Michael, Mardia, K. V. & Hamelryck, Thomas Wim, 2019, In: Statistics and Computing. 29, 1, p. 1-22 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Chromosome-scale haplotype-resolved pangenomics

    Garg, S., Balboa, Renzo Fidel Ferdinando & Kuja, J., 2022, In: Trends in Genetics. 38, 11, p. 1103-1107 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Computational methods for chromosome-scale haplotype reconstruction

    Garg, S., 2021, In: Genome Biology. 22, 24 p., 101.

    Research output: Contribution to journal › Review › Research › peer-review

  5. Published

    Towards routine chromosome-scale haplotype-resolved reconstruction in cancer genomics

    Garg, S., 2023, In: Nature Communications. 14, 1, 11 p., 1358.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Chromatin modifier HUSH co-operates with RNA decay factor NEXT to restrict transposable element expression

    Garland, W., Müller, I., Wu, M., Schmid, M., Imamura, K., Rib, Leonor, Sandelin, Albin Gustav, Helin, K. & Jensen, T. H., 2022, In: Molecular Cell. 82, 9, p. 1691-1707.e8

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2

    Garland, W., Comet, I., Wu, M., Radzisheuskaya, A., Rib, Leonor, Vitting-Seerup, K., Lloret-Llinares, M., Sandelin, Albin Gustav, Helin, K. & Jensen, T. H., 2019, In: Cell Reports. 29, 7, p. 1800-1811 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    CRISPR-Cas adaptive immune systems of the sulfolobales: unravelling their complexity and diversity

    Garrett, Roger Antony, Shah, S. A., Erdmann, S., Guannan, L., Mousaei, M., León Sobrino, C., Peng, W., Islin, S. R., Deng, Ling, Vestergaard, G., Peng, Xu & She, Q., 2015, In: Life. 5, 1, p. 783-817 35 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Estimating inbreeding coefficients from NGS data: impact on genotype calling and allele frequency estimation

    Vieira, Filipe Garrett, Fumagalli, M., Albrechtsen, Anders & Nielsen, Rasmus, 2013, In: Genome Research. 23, p. 1852-1861 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Estimating IBD tracts from low coverage NGS data

    Vieira, Filipe Garrett, Albrechtsen, Anders & Nielsen, Rasmus, 2016, In: Bioinformatics. 32, 14, p. 2096-2102 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Ancient genomes revisit the ancestry of domestic and Przewalski's horses

    Gaunitz, C., Fages, A. A., Hanghøj, K. E., Albrechtsen, A., Khan, N., Schubert, M., Seguin-Orlando, A., Owens, I. J., Felkel, S., Bignon-Lau, O., Damgaard, P. D. B., Mittnik, A., Mohaseb, A. F., Davoudi, H., Alquraishi, S., Alfarhan, A. H., Al-Rasheid, K. A. S., Crubézy, E., Benecke, N., Olsen, S. & 27 others, Brown, D., Anthony, D., Massy, K., Pitulko, V., Kasparov, A., Brem, G., Hofreiter, M., Mukhtarova, G., Baimukhanov, N., Lõugas, L., Onar, V., Stockhammer, P. W., Krause, J., Boldgiv, B., Undrakhbold, S., Erdenebaatar, D., Lepetz, S., Mashkour, M., Ludwig, A., Wallner, B., Merz, V., Merz, I., Zaibert, V., Willerslev, Eske, Sanz, P. L., Outram, A. K. & Orlando, L. A. A., 2018, In: Science. 360, 6384, p. 111-114 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Isolation and characterization of the first Xylanolytic hyperthermophilic euryarchaeon Thermococcus sp strain 2319x1 and its unusual multidomain glycosidase

    Gavrilov, S. N., Stracke, C., Jensen, K., Menzel, P., Kallnik, V., Slesarev, A., Sokolova, T., Zayulina, K., Bräsen, C., Bonch-Osmolovskaya, E. A., Peng, Xu, Kublanov, I. V. & Siebers, B., 2016, In: Frontiers in Microbiology. 7, 17 p., 552.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Light-Dependent Translation Change of Arabidopsis psbA Correlates with RNA Structure Alterations at the Translation Initiation Region

    Gawroński, P., Enroth, Christel Hougård, Kindgren, P., Marquardt, Sebastian, Karpiński, S., Leister, D., Jensen, Poul Erik, Vinther, Jeppe & Scharff, L. B., 2021, In: Cells. 10, 2, 22 p., 322.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The Transcriptional Network That Controls Growth Arrest and Macrophage Differentiation in the Human Myeloid Leukemia Cell Line THP-1

    Gazova, I., Lefevre, L., Bush, S. J., Clohisey, S., Arner, E., de Hoon, M., Severin, J., van Duin, Lucas, Andersson, Robin, Lengeling, A., Hume, D. A. & Summers, K. M., 2020, In: Frontiers in Cell and Developmental Biology. 8, 21 p., 498.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The splicing factor RBM25 controls MYC activity in acute myeloid leukemia

    Ge, Y., Schuster, Mikkel Bruhn, Pundhir, Sachin, Rapin, N., Bagger, F. O., Sidiropoulos, N., Hashem, N. & Porse, Bo Torben, 2019, In: Nature Communications. 10, 1, p. 1-14 14 p., 172.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The impact of PrsA over-expression on the Bacillus subtilis transcriptome during fed-batch fermentation of alpha-amylase production

    Geissler, Adrian Sven, Poulsen, L. D., Doncheva, Nadezhda Tsankova, Anthon, Christian, Seemann, Ernst Stefan, González-Tortuero, E., Breüner, A., Jensen, Lars Juhl, Hjort, C., Vinther, Jeppe & Gorodkin, Jan, 2022, In: Frontiers in Microbiology. 13, 17 p., 909493.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    CRISPRi screen for enhancing heterologous alpha-amylase yield in Bacillus subtilis

    Geissler, Adrian Sven, Fehler, A. O., Poulsen, L. D., Gonzalez-Tortuero, E., Kallehauge, T. B., Alkan, F., Anthon, Christian, Seemann, Ernst Stefan, Rasmussen, M. D., Breuener, A., Hjort, C., Vinther, Jeppe & Gorodkin, Jan, 2023, In: Journal of Industrial Microbiology and Biotechnology. 50, 1, 16 p., kuac028.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Bsgatlas: A unified bacillus subtilis genome and transcriptome annotation atlas with enhanced information access

    Geissler, Adrian Sven, Anthon, Christian, Alkan, F., González-Tortuero, E., Poulsen, L. D., Kallehauge, T. B., Breüner, A., Seemann, Ernst Stefan, Vinther, Jeppe & Gorodkin, Jan, 2021, In: Microbial Genomics. 7, 2, 17 p., 000524.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Software-supported USER cloning strategies for site-directed mutagenesis and DNA assembly

    Genee, H. J., Bonde, M. T., Bagger, F. O., Jespersen, J. B., Sommer, M. O. A., Wernersson, R. & Olsen, L. R., 2015, In: A C S Synthetic Biology. 4, 3, p. 342-349 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Characterizing glucokinase variant mechanisms using a multiplexed abundance assay

    Gersing, S., Schulze, Thea Klarsø, Cagiada, Matteo, Stein, Amelie, Roth, F. P., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2024, In: Genome Biology. 25, 1, 22 p., 98.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Mapping the degradation pathway of a disease-linked aspartoacylase variant

    Gersing, S. K., Wang, Y., Grønbæk-Thygesen, Martin, Kampmeyer, Caroline, Bjørnkjær, Lene, Willemoës, Martin, Andréasson, C., Stein, Amelie, Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2021, In: PLOS Genetics. 17, 4, 28 p., e1009539.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    SatuRn: Scalable analysis of differential transcript usage for bulk and single-cell RNA-sequencing applications

    Gilis, J., Vitting-Seerup, K., Van den Berge, K. & Clement, L., 2022, In: F1000Research. 10, 43 p., 374.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits

    Gilly, A., Suyeges, D., Kuchenbaecker, K., Pollard, M., Southam, L., Hatzikotoulas, K., Farmaki, A-E., Bjornland, T., Waples, R., Appel, E. V. R., Casalone, E., Melloni, G., Kilian, B., Rayner, N. W., Ntalla, I., Kundu, K., Walter, K., Danesh, J., Butterworth, A., Barroso, I. & 5 others, Tsafantakis, E., Dedoussis, G., Zeggini, E., Moltke, Ida & Zeggini, E., 1 Dec 2018, In: Nature Communications. 9, p. 1-9 4674.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Detection of Active Matriptase using a Biotinylated Chloromethyl Ketone Peptide

    Godiksen, S., Soendergaard, C., Friis, S., Jensen, J. K., Lange, Jette Bornholdt, Sales, K. U., Huang, M., Bugge, T. H. & Vogel, Lotte, 2013, In: P L o S One. 8, 10, 10 p., e77146.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    A Generative Angular Model of Protein Structure Evolution

    Golden, M., Garcia-Portugues, E., Sørensen, Michael, Mardia, K. V., Hamelryck, Thomas Wim & Hein, J., Aug 2017, In: Molecular Biology and Evolution. 34, 8, p. 2085-2100

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Bacteriochlorophyllide c C-82 and C-121 methyltransferases are essential for adaptation to low light in Chlorobaculum tepidum

    Gomez Maqueo Chew, A., Frigaard, Niels-Ulrik & Bryant, D. A., 2007, In: Journal of Bacteriology. 189, 17, p. 6176-6184 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Mutational analysis of three bchH paralogs in (bacterio-)chlorophyll biosynthesis in Chlorobaculum tepidum

    Gomez Maqueo Chew, A., Frigaard, Niels-Ulrik & Bryant, D. A., 2009, In: Photosynthesis Research. 101, 1, p. 21-34 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Identification of the bchP gene, encoding geranylgeranyl reductase in Chlorobaculum tepidum

    Gomez Maqueo Chew, A., Frigaard, Niels-Ulrik & Bryant, D. A., 2008, In: Journal of Bacteriology. 190, 2, p. 747-749 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    De novo whole-genome assembly and resequencing resources for the roan (Hippotragus equinus), an iconic African antelope

    Gonçalves, M., Siegismund, Hans Redlef, Van Vuuren, B. J., Koepfli, K., Ferrand, N. & Godinho, R., 2021, In: G3: Genes, Genomes, Genetics. 11, 2, 9 p., jkab002.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Evolutionary history of the roan antelope across its African range

    Gonçalves, M., Siegismund, Hans Redlef, van Vuuren, B. J., Ferrand, N. & Godinho, R., 2021, In: Journal of Biogeography. 48, 11, p. 2812-2827 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    The population genomic legacy of the second plague pandemic

    Gopalakrishnan, S., Ebenesersdóttir, S. S., Lundstrøm, I. K. C., Turner-Walker, G., Moore, K. H. S., Luisi, P., Margaryan, A., Martin, M. D., Ellegaard, M. R., Magnússon, Ó., Sigurðsson, Á., Snorradóttir, S., Magnúsdóttir, D. N., Laffoon, J. E., van Dorp, L., Liu, X., Moltke, I., Ávila-Arcos, M. C., Schraiber, J. G., Rasmussen, S. & 40 others, Juan, D., Gelabert, P., de-Dios, T., Fotaki, Anna Katerina, Iraeta Orbegozo, Miren, Vågene, Åshild Joanne, Denham, S. D., Christophersen, A., Stenøien, H. K., Vieira, Filipe Garrett, Liu, Shanlin, Günther, T., Kivisild, T., Moseng, O. G., Skar, B., Cheung, C., Sandoval-Velasco, Marcela, Wales, N., Schroeder, Hannes, Campos, P. F., Guðmundsdóttir, V. B., Sicheritz-Pontén, Thomas, Petersen, Bent, Halgunset, J., Gilbert, E., Cavalleri, G. L., Hovig, E., Kockum, I., Olsson, T., Alfredsson, L., Hansen, Thomas Folkmann, Werge, Thomas, Willerslev, Eske, Balloux, F., Marques-Bonet, T., Lalueza-Fox, C., Nielsen, Rasmus, Stefánsson, K., Helgason, A. & Gilbert, M Thomas P, 2022, In: Current Biology. 32, 21, p. 4743-4751.e6

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Oncogenic p95HER2 regulates Na+-HCO3- cotransporter NBCn1 mRNA stability in breast cancer cells via 3'UTR-dependent processes

    Gorbatenko, A., Olesen, C. W., Loebl, N., Sigurdsson, H. H., Bianchi, C., Pedraz Cuesta, E., Christiansen, Jan & Pedersen, Stine Helene Falsig, 2016, In: Biochemical Journal. 473, 21, p. 4027-4044 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies

    Gorski, M., Rasheed, H., Teumer, A., Thomas, L. F., Graham, S. E., Sveinbjornsson, G., Winkler, T. W., Günther, F., Stark, K. J., Chai, J-F., Tayo, B. O., Wuttke, M., Li, Y., Tin, A., Ahluwalia, T. S., Ärnlöv, J., Åsvold, B. O., Bakker, S. J. L., Banas, B., Bansal, N. & 29 others, Biggs, M. L., Biino, G., Böhnke, M., Boerwinkle, E., Bottinger, E. P., Brenner, H., Brumpton, B., Carroll, R. J., Chaker, L., Chalmers, J., Chee, M., Chee, M., Cheng, C., Chu, A. Y., Ciullo, M., Cocca, M., Cook, J. P., Coresh, J., Cusi, D., de Borst, M. H., Degenhardt, F., Eckardt, K., Endlich, K., Evans, M. K., Feitosa, M. F., Franke, A., Freitag-Wolf, S., Rossing, Peter & LifeLines Cohort Study, L. C. S., 2022, In: Kidney International. 102, 3, p. 624-639 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    A polygenic architecture with habitat-dependent effects underlies ecological differentiation in Silene

    Gramlich, S., Liu, Xiaodong, Favre, A., Buerkle, C. A. & Karrenberg, S., 2022, In: New Phytologist. 235, 4, p. 1641-1652 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

    Grapotte, M., Saraswat, M., Bessière, C., Menichelli, C., Ramilowski, J. A., Severin, J., Hayashizaki, Y., Itoh, M., Tagami, M., Murata, M., Kojima-Ishiyama, M., Noma, S., Noguchi, S., Kasukawa, T., Hasegawa, A., Suzuki, H., Nishiyori-Sueki, H., Frith, M. C., Abugessaisa, I., Aitken, S. & 31 others, Aken, B. L., Alam, I., Alam, T., Alasiri, R., Alhendi, A. M. N., Alinejad-Rokny, H., Alvarez, M. J., Andersson, Robin, Arakawa, T., Araki, M., Arbel, T., Lange, Jette Bornholdt, Boyd, M., Chen, Y., Coskun, M., Dalby, M., Ienasescu, H., Jørgensen, M., Kaczkowski, B., Kere, J., Li, K., Lilje, B., Nepal, C., Nguyen, Q. H., Nielsen, L. K., Rennie, Sarah, Sandelin, Albin Gustav, Valen, E., Vitezic, M., Vitting-Seerup, K. & FANTOM Consortium, F. C., 2021, In: Nature Communications. 12, 18 p., 3297.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Diabetes in population isolates: lessons from Greenland

    Grarup, Niels, Moltke, Ida, Albrechtsen, Anders & Hansen, Torben, 2015, In: The Review of Diabetic Studies. 12, 3-4, p. 320-329 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  37. Published

    Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets

    Grarup, N., Sulem, P., Sandholt, C. H., Thorleifsson, G., Ahluwalia, T. V. S., Steinthorsdottir, V., Bjarnason, H., Gudbjartsson, D. F., Magnusson, O. T., Sparsø, T., Albrechtsen, A., Kong, A., Masson, G., Tian, G., Cao, H., Nie, C., Kristiansen, K., Husemoen, L. L., Thuesen, B., Li, Y. & 10 others, Nielsen, Rasmus, Linneberg, Allan René, Olafsson, I., Eyjolfsson, G. I., Jørgensen, T., Wang, J., Hansen, Torben, Thorsteinsdottir, U., Stefánsson, K. & Pedersen, Oluf Borbye, 2013, In: P L o S Genetics. 9, 6, 12 p., e1003530.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects

    Grarup, Niels, Lepola, Mette Andersen, Andreasen, C. H., Albrechtsen, Anders, Borch-Johnsen, K., Jørgensen, T., Auwerx, J., Schmitz, O., Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 1, p. 363-6 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes

    Grarup, Niels, Moltke, Ida, Lepola, Mette Andersen, Dalby, M., Vitting-Seerup, K., Kern, T. S., Mahendran, Y., Jørsboe, E., Larsen, C. V. L., Dahl-Petersen, I. K., Gilly, A., Suveges, D., Dedoussis, G., Zeggini, E., Pedersen, Oluf Borbye, Andersson, Robin, Bjerregaard, P., Jørgensen, M. E., Albrechtsen, Anders & Hansen, Torben, 2018, In: Nature Genetics. 50, 2, p. 172-174 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    The -250G>A promoter variant in hepatic lipase associates with elevated fasting serum high-density lipoprotein cholesterol modulated by interaction with physical activity in a study of 16,156 Danish subjects

    Grarup, N., Andreasen, C. H., Lepola, Mette Andersen, Albrechtsen, Anders, Sandbaek, A., Lauritzen, T., Borch-Johnsen, K., Jørgensen, T., Schmitz, O., Hansen, T. & Pedersen, Oluf Borbye, 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 6, p. 2294-9 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population

    Grarup, Niels, Moltke, Ida, Lepola, Mette Andersen, Bjerregaard, P., Larsen, C. V. L., Dahl-Petersen, I. K., Jørsboe, E., Tiwari, H. K., Hopkins, S. E., Wiener, H. W., Boyer, B. B., Linneberg, Allan René, Pedersen, Oluf Borbye, Jørgensen, M. E., Albrechtsen, Anders & Hansen, Torben, 1 Sep 2018, In: Diabetologia. 61, 9, p. 2005–2015

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes.

    Grarup, Niels, Andersen, G., Krarup, N. T., Albrechtsen, Anders, Schmitz, O., Jørgensen, T., Borch-Johnsen, K., Hansen, Torben & Pedersen, Oluf Borbye, 2008, In: Diabetes. 57, 9, p. 2534-40 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Dominance of a clonal green sulfur bacterial population in a stratified lake

    Gregersen, Lea Haarup, Habicht, K. S., Peduzzi, S., Tonolla, M., Canfield, D. E., Miller, M., Cox, R. P. & Frigaard, Niels-Ulrik, 2009, In: FEMS Microbiology Ecology. 70, 1, p. 30-41 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    MicroRNA-145 targets YES and STAT1 in colon cancer cells

    Gregersen, Lea Haarup, Jacobsen, A. B., Frankel, Lisa, Wen, J., Krogh, Anders & Lund, Anders H., 2010, In: PLoS ONE. 5, 1, p. e8836

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    microRNA-143 down-regulates Hexokinase 2 in colon cancer cells

    Gregersen, Lea Haarup, Jacobsen, A., Frankel, Lisa, Wen, J., Krogh, Anders & Lund, Anders H., 2012, In: B M C Cancer. 12, 232, 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    DNA metabarcoding illuminates the contribution of small and very small prey taxa to the diet of lions

    Groen, K., Beekenkamp, S., de Iongh, H. H., Lesilau, F., Chege, M., Narisha, L., Veldhuis, M., Bertola, Laura, van Bodegom, P. M. & Trimbos, K. B., 2023, In: Environmental DNA. 5, 6, p. 1321-1331 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Drosha regulates gene expression independently of RNA cleavage function

    Gromak, N., Dienstbier, M., Macias, S., Plass, M., Eyras, E., Cáceres, J. F. & Proudfoot, N. J., 2013, In: Cell Reports. 5, 6, p. 1499-510 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    scVAE: variational auto-encoders for single-cell gene expression data

    Grønbech, Christopher Heje, Vording, M. F., Timshel, P., Sønderby, C. K., Pers, Tune H & Winther, Ole, 2020, In: Bioinformatics. 36, 16, p. 4415-4422 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Context dependent prediction in DNA sequence using neural networks

    Grønbæk, Christian, Liang, Yuhu, Elliott, Desmond & Krogh, Anders, 2022, In: PeerJ. 10, 22 p., e13666.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    GISA: using Gauss Integrals to identify rare conformations in protein structures

    Grønbæk, Christian, Hamelryck, Thomas Wim & Røgen, P., 2020, In: PeerJ. 8, 16 p., e9159.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    CTCF-KDM4A complex correlates with histone modifications that negatively regulate CHD5 gene expression in cancer cell lines

    Guerra-Calderas, L., González-Barrios, R., Patiño, C. C., Alcaraz, N., Salgado-Albarrán, M., de León, D. C., Hernández, C. C., Sánchez-Pérez, Y., Maldonado-Martínez, H. A., De la Rosa-Velazquez, I. A., Vargas-Romero, F., Herrera, L. A., García-Carrancá, A. & Soto-Reyes, E., 2018, In: OncoTarget. 9, 24, p. 17028-17042 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Population size and social structure of lions in a west African protected area

    Gueye, M., Pellaton, R., Van Cauteren, D., Mengual, L., Van Dongen, S., Leirs, H., Bertola, Laura, Faye, P. M., Diop, B., Diop, M. M., Kanté, A. & de Iongh, H., 2024, In: African Journal of Ecology. 62, 1, 11 p., e13226.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Conflicts between large carnivores and local pastoralists around Niokolo Koba National Park, Senegal

    Gueye, M., Van Cauteren, D., Mengual, L., Pellaton, R., Leirs, H., Bertola, Laura & de Iongh, H., 2022, In: European Journal of Wildlife Research. 68, 1, 11 p., 9.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Identifying the genetic causes of phenotypically diagnosed Pakistani mucopolysaccharidoses patients by whole genome sequencing

    Gul, Rutaba, Firasat, S., Schubert, Mikkel, Ullah, A., Peña, E., Thuesen, Anne Cathrine Baun, Hussain, M., Stæger, Frederik Filip Vinggaard, Gjesing, A. P., Albrechtsen, Anders & Hansen, Torben, 2023, In: Frontiers in Genetics. 14, 13 p., 1128850.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Requirement of a deeply conserved ARGONAUTE phospho-cluster for target- mediated microRNA degradation in plants

    Guo, F., 2022, Department of Biology, Faculty of Science, University of Copenhagen. 118 p.

    Research output: Book/Report › Ph.D. thesis › Research

  56. Published

    YeastFab: The design and construction of standard biological parts for metabolic engineering in Saccharomyces cerevisiae

    Guo, Y., Dong, J., Zhou, T., Auxillos, Jamie Yam, Li, T., Zhang, W., Wang, L., Shen, Y., Luo, Y., Zheng, Y., Lin, J., Chen, G. Q., Wu, Q., Cai, Y. & Dai, J., 27 Apr 2015, In: Nucleic Acids Research. 43, 13, p. e88

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    BloodSpot 3.0: a database of gene and protein expression data in normal and malignant haematopoiesis

    Gíslason, M. H., Demircan, G. S., Prachar, Marek, Furtwängler, Benjamin, Schwaller, J., Schoof, E., Porse, Bo Torben, Rapin, N. & Bagger, F., 2024, In: Nucleic acids symposium series. 52, D1, p. D1138–D1142 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Acute Genome-wide effects of Rosiglitazone on PPARγ transcriptional networks in Adipocytes

    Haakonsson, A. K., Madsen, M. S., Nielsen, R., Sandelin, Albin Gustav & Mandrup, S., 2013, In: Molecular Endocrinology. 27, 9, p. 1536-1549 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Interactions between Barley a-Amylases, Substrates, Inhibitors and Regulatory Proteins

    Hachem, M. A., Bozonnet, S., Willemoës, Martin, Bønsager, B. C., Nielsen, M. M., Fukuda, K., Kramhøft, B., Maeda, K., Sigurskjold, B. W., Hägglund, P., Finnie, C., Mori, H., Robert, X., Jensen, M. H., Tranier, S., Aghajari, N., Haser, R. & Svensson, B., 2006, In: Journal of Applied Glycoscience. 53, 2, p. 163-169

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    FoxA1 in synergy with IFNβ controls PDL1 expression in anti-inflammatory T cells via binding to a 60-nucleotide region in the Pdl1 promoter

    Hadi, M., Rasmussen, L. M., Kosicki, M., Carlsson, R. & Issazadeh-Navikas, Shohreh, Oct 2018, p. 596-597.

    Research output: Contribution to conference › Conference abstract for conference › Research

  61. Published

    Ancient DNA reveals late survival of mammoth and horse in interior Alaska

    Haile, James Seymour, Froese, D. G., Macphee, R. D. E., Roberts, R. G., Arnold, L. J., Reyes, A. V., Rasmussen, M., Nielsen, Rasmus, Brook, B. W., Robinson, S., Demuro, M., Gilbert, M Thomas P, Munch, K., Austin, J. J., Cooper, A., Barnes, I., Möller, P. & Willerslev, Eske, 2009, In: Proceedings of the National Academy of Science of the United States of America. 106, 52, p. 22352-7 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    An Overview of Bayesian Inference and Graphical Models

    Hamelryck, Thomas Wim, 2012, Bayesian Methods in Structural Bioinformatics. Hamelryck, T., Mardia, K. & Ferkinghoff-Borg, J. (eds.). Springer, p. 3-48 46 p. (Statistics for Biology and Health, Springer).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  63. Published

    Probabilistic models and machine learning in structural bioinformatics

    Hamelryck, Thomas Wim, 2009, In: Statistical Methods in Medical Research. 18, 5, p. 505-26 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Potentials of mean force for protein structure prediction vindicated, formalized and generalized

    Hamelryck, Thomas Wim, Borg, M., Paluszewski, M., Paulsen, J., Frellsen, J., Andreetta, C., Boomsma, Wouter, Bottaro, S. & Ferkinghoff-Borg, J., 2010, In: PLoS ONE. 5, 11, 11 p., e13714.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Proteins, physics and probability kinematics: a Bayesian formulation of the protein folding problem

    Hamelryck, Thomas Wim, Boomsma, Wouter, Ferkinghoff-Borg, J., Foldager, J. I., Frellsen, J., Haslett, J. & Theobald, D., 2015, Geometry driven statistics. Dryden, I. L. & Kent, J. T. (eds.). Wiley, p. 356-376 21 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  66. Published

    Bayesian methods in structural bioinformatics

    Hamelryck, Thomas Wim (ed.), Mardia, K. (ed.) & Ferkinghoff-Borg, J. (ed.), 2012, Springer. 377 p. (Statistics for Biology and Health).

    Research output: Book/Report › Book › Research › peer-review

  67. Published

    Persistent Topology of Protein Space

    Hamilton, W., Borgert, J. E., Hamelryck, Thomas Wim & Marron, J. S., 2022, Research in Computational Topology 2. Springer, p. 223-244 (Association for Women in Mathematics Series, Vol. 30).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  68. Published

    Expression of IGF-II mRNA-binding proteins (IMPs) in gonads and testicular cancer

    Hammer, N. A., Hansen, Thomas van Overeem, Byskov, A. G., Rajpert-De Meyts, E., Grøndahl, M. L., Bredkjaer, H. E., Wewer, Ulla M., Christiansen, Jan & Nielsen, Finn Cilius, 2005, In: Reproduction. 130, 2, p. 203-12 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Investigating the possible function of DCL2 as a viral RNA sensor in Arabidopsis

    Han, L., 2019, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  70. Published

    DamMet: ancient methylome mapping accounting for errors, true variants, and post-mortem DNA damage

    Hanghøj, Kristian Ebbesen, Renaud, Gabriel, Albrechtsen, Anders & Orlando, L., 2019, In: GigaScience. 8, 4, 6 p., giz025.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Fast and accurate relatedness estimation from high-throughput sequencing data in the presence of inbreeding

    Hanghøj, Kristian Ebbesen, Moltke, Ida, Andersen, P. A., Manica, A. & Korneliussen, Thorfinn Sand, May 2019, In: GigaScience. 8, 5, 9 p., giz034.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Genomic investigations of horse domestication using ancient DNA and a novel statistical method for epigenomic inference from ancient DNA sequencing data

    Hanghøj, Kristian Ebbesen, 2018, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  73. Published

    Upregulation of alpha cell glucagon-like peptide 1 (GLP-1) in Psammomys obesus--an adaptive response to hyperglycaemia?

    Hansen, A. M. K., Bödvarsdottir, T. B., Nordestgaard, D. N. E., Heller, Rasmus, Gotfredsen, C. F., Maedler, K., Fels, J., Holst, Jens Juul & Karlsen, A., 2011, In: Diabetologia. 54, 6, p. 1379-87 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    H3K9 dimethylation safeguards cancer cells against activation of the interferon pathway

    Hansen, A. M., Ge, Y., Schuster, Mikkel Bruhn, Pundhir, Sachin, Jakobsen, J. S., Kalvisa, A., Tapia, Marta Cecylia, Gordon, Sandra, Ambri, F., Bagger, F. O., Pandey, D., Helin, K. & Porse, Bo Torben, 2022, In: Science Advances. 8, 11, eabf8627.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    The Muskox Lost a Substantial Part of Its Genetic Diversity on Its Long Road to Greenland

    Hansen, C. C. R., Hvilsom, C., Schmidt, N. M., Aastrup, P., de Groot, P. J. V. C., Siegismund, Hans Redlef & Heller, Rasmus, 2018, In: Current Biology. 28, 24, p. 4022-4028, e1-e5

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Genomic diversity and differentiation between island and mainland populations of white-tailed eagles (Haliaeetus albicilla)

    Hansen, C. C. R., Láruson, Á. J., Rasmussen, Jacob Agerbo, Ballesteros, J. A. C., Sinding, Mikkel Holger Strander, Hallgrimsson, G. T., von Schmalensee, M., Stefansson, R. A., Skarphédinsson, K. H., Labansen, A. L., Leivits, M., Sonne, C., Dietz, R., Skelmose, K., Boertmann, D., Eulaers, I., Martin, M. D., Helgason, A. S., Gilbert, M Thomas P & Pálsson, S., 2023, In: Molecular Ecology. 32, 8, p. 1925-1942 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Cardiovascular Autonomic Neuropathy in Type 1 Diabetes Is Associated With Disturbances in TCA, Lipid, and Glucose Metabolism

    Hansen, C. S., Suvitaival, T., Theilade, Karen Simone, Mattila, I., Lajer, M., Trošt, K., Ahonen, L., Hansen, T. W., Legido-Quigley, C., Rossing, Peter & Ahluwalia, Tarun Veer Singh, 2022, In: Frontiers in Endocrinology. 13, 831793.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Drosophila Imp iCLIP identifies an RNA assemblage coordinating F-actin formation

    Hansen, H. T., Rasmussen, S. H., Adolph, S. K., Plass, M., Krogh, Anders, Sanford, J., Nielsen, Finn Cilius & Christiansen, Jan, 2015, In: Genome Biology (Online Edition). 16, 16 p., 123.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    mRNA pseudoknot structures can act as ribosomal roadblocks

    Hansen, J. T., Oddershede, L. B. & Sørensen, Michael Askvad, 2012, In: Nucleic Acids Research. 40, 1, p. 303-313 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Effects of Four Different Regulatory Mechanisms on the Dynamics of Gene Regulatory Cascades

    Hansen, S., Krishna, S., Semsey, S. & Svenningsen, Sine Lo, 17 Jul 2015, In: Scientific Reports. 5, 12186.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    A study of bacterial gene regulatory mechanisms: Dynamic features of gene regulatory mechanisms in EscherichEia coli and small RNA post-transcriptional regulation in Vibrio cholerae

    Hansen, S., 2013, Department of Biology, Faculty of Science, University of Copenhagen. 134 p.

    Research output: Book/Report › Ph.D. thesis › Research

  82. Published

    Between inflammation, homeostasis and adaptation: Systemic and tissue-specific responses to maternal immune activation

    Hansen, Signe Schmidt Kjølner, 2023, Department of Biology, Faculty of Science, University of Copenhagen. 177 p.

    Research output: Book/Report › Ph.D. thesis › Research

  83. Published

    A common Greenlandic Inuit BRCA1 RING domain founder mutation

    Hansen, T. V. O., Ejlertsen, Bent Laursen, Albrechtsen, Anders, Bergsten, E., Bjerregaard, P., Hansen, T., Myrhoj, T., Nielsen, P. B., Timmermans-Wielenga, V., Andersen, M. K., Jonson, L. & Nielsen, F. C., 2009, In: Breast Cancer Research and Treatment. 115, 1, p. 69-76 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Correlation between mechanical strength of messenger RNA pseudoknots and ribosomal frameshifting.

    Hansen, T. M., Reihani, S. N. S., Oddershede, L. B. & Sørensen, Michael Askvad, 2007, In: Proceedings of the National Academy of Science of the United States of America. 104, 14, p. 5830-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Dwarfism and impaired gut development in insulin-like growth factor II mRNA-binding protein 1-deficient mice

    Hansen, Thomas van Overeem, Hammer, N. A., Nielsen, J., Madsen, Mette, Dalbaeck, C., Wewer, Ulla M., Christiansen, Jan & Nielsen, Finn Cilius, 2004, In: Molecular and Cellular Biology. 24, 10, p. 4448-64 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Large BRCA1 and BRCA2 genomic rearrangements in Danish high risk breast-ovarian cancer families

    Hansen, Thomas van Overeem, Jønson, L., Albrechtsen, Anders, Andersen, M. K., Ejlertsen, Bent Laursen & Nielsen, Finn Cilius, May 2009, In: Breast Cancer Research and Treatment. 115, 2, p. 315-323 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. E-pub ahead of print

    High N6-methyladenosine-activated TCEAL8 mRNA is a novel pancreatic cancer marker

    Hara, T., Meng, S., Sato, H., Tatekawa, S., Sasaki, K., Takeda, Y., Tsuji, Y., Arao, Y., Ofusa, K., Kitagawa, T., Yamada, D., Takahashi, H., Kobayashi, S., Motooka, D., Suzuki, Y., Rennie, S., Uchida, S., Mori, M., Ogawa, K., Doki, Y. & 2 others, Eguchi, H. & Ishii, H., 2024, (E-pub ahead of print) In: Cancer Science.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Beyond rotamers: a generative, probabilistic model of side chains in proteins

    Harder, T., Boomsma, Wouter, Paluszewski, M., Frellsen, J., Johansson, Kristoffer Enøe & Hamelryck, Thomas Wim, 1 Jan 2010, In: B M C Bioinformatics. 11, p. 306

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    An efficient null model for conformational fluctuations in proteins

    Harder, T. P., Bottaro, S., Boomsma, Wouter, Olsson, S., Ferkinghoff-Borg, J. & Hamelryck, Thomas Wim, 2012, In: Structure. 20, 6, p. 1028-1039 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Exploring the conformational space of proteins using probabilistic models

    Harder, T. P., 2011

    Research output: Book/Report › Ph.D. thesis › Research

  91. Published

    Fast large-scale clustering of protein structures using Gauss integrals

    Harder, T. P., Borg, M., Boomsma, Wouter, Røgen, P. & Hamelryck, Thomas Wim, 2012, In: Bioinformatics. 28, 4, p. 510-515 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Inferring demographic history from a spectrum of shared haplotype lengths

    Harris, K. & Nielsen, Rasmus, 2013, In: P L o S Genetics. 9, 6, 20 p., e1003521.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Error-prone polymerase activity causes multinucleotide mutations in humans

    Harris, K. & Nielsen, Rasmus, 1 Sep 2014, In: Genome Research. 24, 9, p. 1445-1454 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    C/EBPα Is Required for Long-Term Self-Renewal and Lineage Priming of Hematopoietic Stem Cells and for the Maintenance of Epigenetic Configurations in Multipotent Progenitors

    Hasemann, M. S., Lauridsen, F. K. B., Waage, J., Jakobsen, J. S., Frank, Anne-Katrine, Schuster, Mikkel Bruhn, Rapin, N. P. J., Bagger, F. O., Hoppe, P. S., Schroeder, T. & Porse, Bo Torben, Jan 2014, In: P L o S Genetics (Online). 10, 1, p. 1-10 10 p., e1004079.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Inbreeding and outbreeding effects on pollen fitness and zygote survival in Silene nutans (Caryophyllaceae)

    Hauser, T. P. & Siegismund, Hans Redlef, 2000, In: Journal of Evolutionary Biology. 13, p. 446-454 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    A fluorescent substrate for carbon-phosphorus lyase: towards the pathway for organophosphonate metabolism in bacteria

    He, S., Lou, Y., Hove-Jensen, B. & Zechel, D. L., 2009, In: Bioorganic & Medicinal Chemistry Letters. 19, 20, p. 5954-5957

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Quantitative Evaluation of Stem-like Markers of Human Glioblastoma Using Single-Cell RNA Sequencing Datasets

    He, Yue, Døssing, Kristina Benedikte V, Sloth, Ane Beth, He, Xuening, Rossing, M. & Kjær, Andreas, 2023, In: Cancers. 15, 5, 16 p., 1557.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Can small wildlife conservancies maintain genetically stable populations of large mammals? Evidence for increased genetic drift in geographically restricted populations of Cape buffalo in East Africa

    Heller, Rasmus, Okello, J. B. A. & Siegismund, Hans Redlef, 2010, In: Molecular Ecology. 19, 7, p. 1324-34 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Are East African conservancies too small and isolated to maintain migratory bovid populations?

    Heller, Rasmus, Okello, J. B. A. & Siegismund, Hans Redlef, 2011, In: Gnusletter. 29, 2, p. 20-21

    Research output: Contribution to journal › Journal article › Research

  100. Published

    Cape buffalo mitogenomics reveals a holocene shift in the African human-megafauna dynamics

    Heller, Rasmus, Brüniche-Olsen, A. & Siegismund, Hans Redlef, 2012, In: Molecular Ecology. 21, 16, p. 3947-3959 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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