Computational and RNA Biology

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  1. Published

    Darwinian and demographic forces affecting human protein coding genes.

    Nielsen, Rasmus, Hubisz, M. J., Hellmann, I., Torgerson, D., Andres, A. M., Albrechtsen, Anders, Gutenkunst, R., Adams, M. D., Cargill, M., Boyko, A., Indap, A., Bustamante, C. D. & Clark, A. G., 2009, In: Genome Research. 19, 5, p. 838-49 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Statistical inferences in phylogeography

    Nielsen, Rasmus & Beaumont, M. A., 2009, In: Molecular Ecology. 18, 6, p. 1034-47 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    SNP calling, genotype calling, and sample allele frequency estimation from new-generation sequencing data

    Nielsen, Rasmus, Korneliussen, Thorfinn Sand, Albrechtsen, Anders, Li, Y. & Wang, J., 2012, In: PLoS ONE. 7, 7, 11 p., e37558.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Protein destabilization and degradation as a mechanism for hereditary disease

    Nielsen, S. V., Schenstrøm, S. M., Christensen, Caspar Elo, Stein, Amelie, Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2020, Protein Homeostasis Diseases: Mechanisms and Novel Therapies. Pey, A. L. (ed.). Elsevier, p. 111-125

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  5. Published

    Multiplexed assays reveal effects of missense variants in MSH2 and cancer predisposition

    Nielsen, S. V., Hartmann-Petersen, Rasmus, Stein, Amelie & Lindorff-Larsen, Kresten, 2021, In: PLOS Genetics. 17, 4, 6 p., e1009496.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Mapping the human genetic architecture of COVID-19

    Niemi, M. E. K., Karjalainen, J., Liao, R. G., Neale, B. M., Daly, M., Ganna, A., Pathak, G. A., Andrews, S. J., Kanai, M., Veerapen, K., Fernandez-Cadenas, I., Schulte, E. C., Striano, P., Marttila, M., Minica, C., Marouli, E., Karim, M. A., Wendt, F. R., Savage, J., Sloofman, L. & 41 others, Butler-Laporte, G., Kim, H., Kanoni, S., Okada, Y., Byun, J., Han, Y., Uddin, M. J., Smith, G. D., Willer, C. J., Buxbaum, J. D., Karjalainen, J., Mehtonen, J., Folkersen, L., Moltke, Ida, Hinney, A., Wang, C., Ellinghaus, D., Brunak, Søren, Castro, P., Guindo Martínez, Marta, Lee, J. Y., Loos, Ruth, Zhao, J. H., Sun, Y. V., Wang, B., Parker, R., Garcia, S. M., Smith, O., Davis, C., COVID-19 Host Genetics Initiative, C. H. G. I., 23andMe COVID-19 Team, 2. C. T., Norwegian SARS-CoV-2 Study Grp, N. S. S. G., Humanitas COVID-19 Task Force, H. C. T. F., Humanitas Gavazzeni COVID-19 Task, H. G. C. T., FHoGID, F., RegCOVID, R., P-PredictUs, P., SeroCOVID, S., CRiPSI, C., Genes & Hlth Res Team, G. &. H. R. T. & UCLA Hlth ATLAS Data Mart Working, U. H. A. D. M. W., 2021, In: Nature. 600, p. 472-477

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Binning microbial genomes using deep learning

    Nissen, J. N., Sønderby, C. K., Armenteros, J. J. A., Grønbech, Christopher Heje, Nielsen, H. B., Petersen, T. N., Winther, Ole & Rasmussen, Simon, 2018, (bioRxiv).

    Research output: Working paper › Preprint

  8. Published

    Improved metagenome binning and assembly using deep variational autoencoders

    Nissen, J. N., Johansen, Joachim, Allesoe, R. L., Sonderby, C. K., Armenteros, J. J. A., Grønbech, Christopher Heje, Jensen, Lars Juhl, Nielsen, H. B., Petersen, T. N., Winther, Ole & Rasmussen, Simon, 2021, In: Nature Biotechnology. 39, p. 555-560

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Effect of supercoiling on the λ switch

    Norregaard, K., Andersson, M., Sneppen, Kim, Nielsen, Peter E., Brown, Stanley & Oddershede, L. B., 1 Jan 2014, In: Bacteriophage. 4, 2, p. 1-5 5 p., e27517.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    DNA supercoiling enhances cooperativity and efficiency of an epigenetic switch

    Norregaard, K., Andersson, M., Sneppen, Kim, Nielsen, Peter E., Brown, Stanley & Oddershede, L. B., 22 Oct 2013, In: Proceedings of the National Academy of Sciences USA (PNAS). 110, 43, p. 17386-91 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The whole-genome landscape of medulloblastoma subtypes

    Northcott, P. A., Buchhalter, I., Morrissy, A. S., Hovestadt, V., Weischenfeldt, J., Ehrenberger, T., Gröbner, S., Segura-Wang, M., Zichner, T., Rudneva, V. A., Warnatz, H. J., Sidiropoulos, N., Phillips, A. H., Schumacher, S., Kleinheinz, K., Waszak, S. M., Erkek, S., Jones, D. T. W., Worst, B. C., Kool, M. & 67 others, Zapatka, M., Jäger, N., Chavez, L., Hutter, B., Bieg, M., Paramasivam, N., Heinold, M., Gu, Z., Ishaque, N., Jäger-Schmidt, C., Imbusch, C. D., Jugold, A., Hübschmann, D., Risch, T., Amstislavskiy, V., Gonzalez, F. G. R., Weber, U. D., Wolf, S., Robinson, G. W., Zhou, X., Wu, G., Finkelstein, D., Liu, Y., Cavalli, F. M. G., Luu, B., Ramaswamy, V., Wu, X., Koster, J., Ryzhova, M., Cho, Y. J., Pomeroy, S. L., Herold-Mende, C., Schuhmann, M., Ebinger, M., Liau, L. M., Mora, J., McLendon, R. E., Jabado, N., Kumabe, T., Chuah, E., Ma, Y., Moore, R. A., Mungall, A. J., Mungall, K. L., Thiessen, N., Tse, K., Wong, T., Jones, S. J. M., Witt, O., Milde, T., Von Deimling, A., Capper, D., Korshunov, A., Yaspo, M. L., Kriwacki, R., Gajjar, A., Zhang, J., Beroukhim, R., Fraenkel, E., Korbel, J. O., Brors, B., Schlesner, M., Eils, R., Marra, M. A., Pfister, S. M., Taylor, M. D. & Lichter, P., 19 Jul 2017, In: Nature. 547, 7663, p. 311-317 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Polyadenylation site-induced decay of upstream transcripts enforces promoter directionality

    Ntini, E., Järvelin, A. I., Lange, Jette Bornholdt, Chen, Y., Boyd, M., Jørgensen, M., Andersson, Robin, Hoof, I., Schein, A., Andersen, P. R., Andersen, P. K., Preker, P., Valen, E., Zhao, X., Pelechano, V., Steinmetz, L. M., Sandelin, Albin Gustav & Jensen, T. H., 2013, In: Nature Structural and Molecular Biology. 20, p. 923-928 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Joint identification of sex and sex-linked scaffolds in non-model organisms using low depth sequencing data

    Nursyifa, Casia, Brüniche-Olsen, Anna, Garcia Erill, Genís, Heller, Rasmus & Albrechtsen, Anders, 2022, In: Molecular Ecology Resources. 22, 2, p. 458-467 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Application of whole genome sequencing data in population genetics: identifying sex-linked scaffolds and inferring admixture in a unique cattle population

    Nursyifa, Casia, 2023, Department of Biology, Faculty of Science, University of Copenhagen. 225 p.

    Research output: Book/Report › Ph.D. thesis › Research

  15. Published

    Long- and short-term selective forces on malaria parasite genomes

    Nygaard, S., Braunstein, A., Malsen, G., Van Dongen, S., Gardner, P. P., Krogh, Anders, Otto, T. D., Pain, A., Berriman, M., McAuliffe, J., Dermitzakis, E. T. & Jeffares, D. C., 1 Sep 2010, In: P L o S Genetics. 6, 9

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The genome of the leaf-cutting ant Acromyrmex echinatior suggests key adaptations to advanced social life and fungus farming

    Nygaard, S., Zhang, G., Schiøtt, M., Li, C., Wurm, Y., Hu, H., Zhou, J., Ji, L., Qiu, F., Rasmussen, M., Pan, H., Hauser, Frank, Krogh, Anders, Grimmelikhuijzen, Cornelis (Cok), Wang, J. & Boomsma, Jacobus J., 2011, In: Genome Research. 21, 8, p. 1339-1348 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    NGSremix: A software tool for estimating pairwise relatedness between admixed individuals from next-generation sequencing data

    Nøhr, A. K., Hanghøj, Kristian Ebbesen, Garcia Erill, Genís, Li, Zilong, Moltke, Ida & Albrechtsen, Anders, 2021, In: G3: Genes, Genomes, Genetics. 11, 8, 8 p., jkab174.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Exploring antidepressant treatment response using biological and clinical measurements

    Nøhr, A. K., 2023, Department of Biology, Faculty of Science, University of Copenhagen. 125 p.

    Research output: Book/Report › Ph.D. thesis › Research

  19. Published

    Polygenic heterogeneity in antidepressant treatment and placebo response

    Nøhr, A. K., Forsingdal, A., Moltke, Ida, Howes, O. D., Vitezic, M., Albrechtsen, Anders & Dalby, M., 2022, In: Translational Psychiatry. 12, 8 p., 456.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Predictors and trajectories of treatment response to SSRIs in patients suffering from PTSD

    Nøhr, A. K., Eriksson, H., Hobart, M., Moltke, Ida, Buller, R., Albrechtsen, Anders & Lindgreen, S., 2021, In: Psychiatry Research. 301, 8 p., 113964.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    A large-scale genome-wide gene expression analysis in peripheral blood identifies very few differentially expressed genes related to antidepressant treatment and response in patients with major depressive disorder

    Nøhr, A. K., Lindow, M., Forsingdal, A., Demharter, S., Nielsen, T., Buller, R., Moltke, Ida, Vitezic, M. & Albrechtsen, Anders, 2021, In: Neuropsychopharmacology. 46, 7, p. 1324-1332 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    E. coli dihydroorotate dehydrogenase reveals structural and functional distinctions between different classes of dihydroorotate dehydrogenases.

    Nørager, S., Jensen, K. F., Björnberg, O. & Larsen, Sine, 2002, In: Structure. 10, p. 1211-1223

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    SPT6-driven error-free DNA repair safeguards genomic stability of glioblastoma cancer stem-like cells

    Obara, E. A. A., Aguilar-Morante, D., Rasmussen, R. D., Frias, A., Vitting-Serup, K., Lim, Y. C., Elbæk, K. J., Pedersen, H., Vardouli, L., Jensen, K. E., Skjoth-Rasmussen, J., Brennum, J., Tuckova, L., Strauss, R., Dinant, C., Bartek, J. & Hamerlik, P., 2020, In: Nature Communications. 11, 14 p., 4709.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    The Motion of a Single Molecule, the Lambda-Receptor, in the Bacterial Outer Membrane

    Oddershede, L., Dreyer, J. K., Grego, S., Brown, Stanley & Berg-Sørensen, K., 2002, In: Biophysical Journal. 83, 6, p. 3152-61 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Initiation of MLL-rearranged AML is dependent on C/EBPα

    Ohlsson, E., Hasemann, M. S., Willer, A., Lauridsen, F. K. B., Rapin, N. P. J., Jendholm, L. J. & Porse, Bo Torben, 13 Jan 2014, In: The Journal of Experimental Medicine. 211, 1, p. 5-13 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    RECLU: a pipeline to discover reproducible transcriptional start sites and their alternative regulation using capped analysis of gene expression (CAGE)

    Ohmiya, H., Vitezic, M., Frith, M. C., Itoh, M., Carninci, P., Forrest, A. R. R., Hayashizaki, Y., Lassmann, T. & The FANTOM Consortium, T. F. C., 2014, In: B M C Genomics. 15, 15 p., 269.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Marine genomics: news and views

    Oliveira Ribeiro, Â. M., Foote, A. D., Kupczok, A., Frazão, B., Limborg, Morten Tønsberg, Piñeiro, R., Abalde, S., Rocha, S. & Rodrigues da Fonseca, Rute Andreia, Feb 2017, In: Marine Genomics. 31, p. 1-8 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  28. Published

    Current and emerging approaches to define intestinal epithelium-specific transcriptional networks

    Olsen, A. K., Boyd, M., Danielsen, E. T. & Troelsen, J. T., Feb 2012, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 302, 3, p. G277-86

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Tumor antigens as proteogenomic biomarkers in invasive ductal carcinomas

    Olsen, L. R., Campos, B., Winther, Ole, Sgroi, D. C., Karger, B. L. & Brusic, V., 2014, In: B M C Medical Genomics. 7, 3, p. 1-13 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    BlockLogo: visualization of peptide and sequence motif conservation

    Olsen, L. R., Kudahl, U. J., Simon, C., Sun, J., Schönbach, C., Reinherz, E. L., Zhang, G. L. & Brusic, V., 2013, In: Journal of Immunological Methods. 400-401, p. 37-44 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    The Prognostic, Diagnostic, and Therapeutic Potential of Tumor Antigens

    Olsen, L. R., 2013, Department of Biology, Faculty of Science, University of Copenhagen. 271 p.

    Research output: Book/Report › Ph.D. thesis › Research

  32. Published

    Literature classification for semi-automated updating of biological knowledgebases

    Olsen, L. R., Kudahl, U. J., Winther, Ole & Brusic, V., 2013, In: B M C Genomics. 14(Suppl 5), 10 p., S14.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Bioinformatics for cancer immunotherapy target discovery

    Olsen, L. R., Campos, B., Stein Barnkob, M., Winther, Ole, Brusic, V. & Andersen, M. H., 2014, In: Cancer Immunology, Immunotherapy. 63, 12, p. 1235-1249 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    A computational method for identification of vaccine targets from protein regions of conserved human leukocyte antigen binding

    Olsen, L. R., Simon, C., Kudahl, U. J., Bagger, F. O., Winther, Ole, Reinherz, E. L., Zhang, G. L. & Brusic, V., 2015, In: B M C Medical Genomics. 8, Suppl 4, 6 p., 5.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Integrating genetic data and population viability analyses for the identification of harbour seal (Phoca vitulina) populations and management units

    Olsen, Morten Tange, Andersen, L. W., Dietz, R., Teilmann, J., Härkönen, T. & Siegismund, Hans Redlef, 2014, In: Molecular Ecology. 23, 4, p. 815-831 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Probabilistic determination of native state ensembles of proteins

    Olsson, S., Vögeli, B. R., Cavalli, A., Boomsma, Wouter, Ferkinghoff-Borg, J., Lindorff-Larsen, Kresten & Hamelryck, Thomas Wim, 2014, In: Journal of Chemical Theory and Computation. 10, 8, p. 3484-3491 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Inference of structure ensembles of flexible biomolecules from sparse, averaged data

    Olsson, S., Frellsen, J., Boomsma, Wouter, Mardia, K. V. & Hamelryck, Thomas Wim, 2013, In: PLoS ONE. 8, 11, 7 p., e79439.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Generative probabilistic models extend the scope of inferential structure determination

    Olsson, S., Boomsma, Wouter, Frellsen, J., Bottaro, S., Harder, T. P., Ferkinghoff-Borg, J. & Hamelryck, Thomas Wim, 2011, In: Journal of Magnetic Resonance. 213, 1, p. 182-186 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  39. Published

    Inference problems in structural biology: protein structures and protein structure ensembles

    Olsson, S., 2013, Department of Biology, Faculty of Science, University of Copenhagen. 138 p.

    Research output: Book/Report › Ph.D. thesis › Research

  40. Published

    A community proposal to integrate structural bioinformatics activities in ELIXIR (3D-Bioinfo Community) [version 1; peer review: 1 approved, 3 approved with reservations]

    Orengo, C., Velankar, S., Wodak, S., Zoete, V., Bonvin, A. M. J. J., Elofsson, A., Feenstra, K. A., Gerloff, D. L., Hamelryck, T., Hancock, J. M., Helmer-Citterich, M., Hospital, A., Orozco, M., Perrakis, A., Rarey, M., Soares, C., Sussman, J. L., Thornton, J. M., Tuffery, P., Tusnady, G. & 3 others, Wierenga, R., Salminen, T. & Schneider, B., 2020, In: F1000Research. 9, 27 p., 278.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    True single-molecule DNA sequencing of a pleistocene horse bone

    Orlando, L. A. A., Ginolhac, A., Raghavan, M., Mouatt, J. T. V., Rasmussen, M., Magnussen, K., Steinmann, K. E., Kapranov, P., Thompson, J. F., Zazula, G., Froese, D., Moltke, Ida, Shapiro, B., Hofreiter, M., Al-Rasheid, K. A. S., Gilbert, M Thomas P & Willerslev, Eske, 2011, In: Genome Research. 21, 10, p. 1705-1719 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse

    Orlando, L. A. A., Ginolhac, A., Zhang, G., Froese, D., Albrechtsen, A., Stiller, M., Schubert, M., Cappellini, E., Petersen, B., Moltke, I., Johnson, P. L. F., Fumagalli, M., Mouatt, J. T. V., Raghavan, M., Korneliussen, T. S., Malaspinas, A. S., Vogt, J., Szklarczyk, D. M., Kelstrup, C., Vinther, J. & 36 others, Dolocan, A., Stenderup, Jesper Tandberg, Velazquez, A. M. V., Cahill, J., Rasmussen, M., Wang, X., Min, J., Zazula, G. D., Seguin-Orlando, A., Mortensen, C., Magnussen, K., Thompson, J. F., Weinstock, J., Gregersen, K., Røed, K. H., Eisenmann, V., Rubin, C. J., Miller, D. C., Antczak, D. F., Bertelsen, M. F., Brunak, S., Al-Rasheid, K. A. S., Ryder, O., Andersson, L., Mundy, J., Krogh, Anders, Gilbert, M Thomas P, Kjær, Kurt H., Sicheritz-Pontén, T., Jensen, Lars Juhl, Olsen, Jesper Velgaard, Hofreiter, M., Nielsen, R., Shapiro, B., Wang, J. & Willerslev, Eske, 4 Jul 2013, In: Nature. 499, 7456, p. 74-78 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  43. Published

    Bacterial natural transformation by highly fragmented and damaged DNA

    Overballe-Petersen, S., Harms, K., Orlando, L. A. A., Moreno Mayar, J. Víctor, Rasmussen, Simon, Dahl, Tais Wittchen, Rosing, Minik Thorleif, Poole, A. M., Sicheritz-Ponten, T., Brunak, S., Inselmann, S., de Vries, J., Wackernagel, W., Pybus, O. G., Nielsen, Rasmus, Johnsen, P. J., Nielsen, K. M. & Willerslev, Eske, 3 Dec 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 49, p. 19860–19865 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    The effect of diabetes and the common diabetogenic TBC1D4 p.Arg684Ter variant on cardiovascular risk in Inuit in Greenland

    Overvad, M., Diaz, L. J., Bjerregaard, P., Pedersen, M. L., Larsen, C. V. L., Senftleber, N., Grarup, Niels, Hansen, Torben & Jørgensen, M. E., 2020, In: Scientific Reports. 10, 9 p., 22081.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    netDx: Software for building interpretable patient classifiers by multi-'omic data integration using patient similarity networks [version 2; peer review: 2 approved]

    Pai, S., Weber, P., Isserlin, R., Kaka, H., Hui, S., Shah, M. A., Giudice, L., Giugno, R., Nøhr, A. K., Baumbach, J. & Bader, G. D., 2021, In: F1000Research. 9, 42 p., 1239.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Uncovering commensal bacteria-plant interaction: characterisation of bacterial endophytes and their population structures in the model plant Arabidopsis thaliana

    Paiva, D. S., Klepac-Ceraj, V., Lemon, K., Kolter, R., Frigaard, Niels-Ulrik, Gautier, L. & Sakuragi, Y., 2009.

    Research output: Contribution to conference › Conference abstract for conference › Research

  47. Published

    Mocapy++ - a toolkit for inference and learning in dynamic Bayesian networks

    Paluszewski, M. & Hamelryck, Thomas Wim, 2010, In: BMC Bioinformatics. 11, Suppl 1, 6 p., 126.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Reconstructing protein structure from solvent exposure using tabu search

    Paluszewski, M., Hamelryck, Thomas Wim & Winter, Pawel, 2006, In: Algorithms for Molecular Biology. 1, p. 14

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    A New Paradigm for General Architecture Routing

    Paluszewski, M., Winter, Pawel & Zachariasen, M., 2004, Proceedings of the 14th ACM Great Lakes Symposium on VLSI. New York, NY, USA: Association for Computing Machinery, p. 202-207

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  50. Published

    Protein Decoy Generation Using Branch and Bound with Efficient Bounding

    Paluszewski, M. & Winter, Pawel, 2008, Algorithms in Bioinformatics: 8th International Workshop, WABI 2008, Karlsruhe, Germany, September 15-19, 2008, Proceedings. Crandall, K. A. & Lagergren, J. (eds.). Springer, p. 382-393 12 p. (Lecture Notes in Computer Science : Lecture Notes in Bioinformatics; No. 5251).

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

  51. Published

    Protein structure prediction using tabu search and half-sphere exposure measure

    Paluszewski, M., Hamelryck, Thomas Wim & Winter, Pawel, 2006.

    Research output: Contribution to conference › Poster › Research

  52. Published

    Modes of genetic adaptations underlying functional innovations in the rumen

    Pan, X., Cai, Y., Li, Z., Chen, X., Heller, R., Wang, N., Wang, Y., Zhao, C., Wang, Y., Xu, H., Li, S., Li, M., Li, C., Hu, S., Li, H., Wang, K., Chen, L., Wei, B., Zheng, Z., Fu, W. & 20 others, Yang, Y., Zhang, T., Hou, Z., Yan, Y., Lv, X., Sun, W., Li, X., Huang, S., Liu, L., Mao, S., Liu, W., Hua, J., Li, Z., KU, thw266, Chen, Y., Wang, X., Qiu, Q., Dalrymple, B. P., Wang, W. & Jiang, Y., 2021, In: Science China Life Sciences. 64, 1, p. 1-21 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    CNEReg Interprets Ruminant-specific Conserved Non-coding Elements by Developmental Gene Regulatory Network

    Pan, X., Ma, Z., Sun, X., Li, H., Zhang, T., Zhao, C., Wang, N., Heller, Rasmus, Hung Wong, W., Wang, W., Jiang, Y. & Wang, Y., 2023, In: Genomics, Proteomics and Bioinformatics. 21, 3, p. 632-648 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Massively targeted evaluation of therapeutic CRISPR off-targets in cells

    Pan, X., Qu, K., Yuan, H., Xiang, X., Anthon, C., Pashkova, L., Liang, X., Han, P., Corsi, G. I., Xu, F., Liu, P., Zhong, J., Zhou, Y., Ma, T., Jiang, H., Liu, J., Wang, J., Jessen, N., Bolund, L., Yang, H. & 5 others, Xu, X., Church, G. M., Gorodkin, Jan, Lin, L. & Luo, Y., 2022, In: Nature Communications. 13, 14 p., 4049.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    miR-509-3p is clinically significant and strongly attenuates cellular migration and multi-cellular spheroids in ovarian cancer

    Pan, Y., Robertson, G., Pedersen, L., Lim, E., Hernandez-Herrera, A., Rowat, A. C., Patil, S. L., Chan, C. K., Wen, Y., Zhang, X., Basu-Roy, U., Mansukhani, A., Chu, A., Sipahimalani, P., Bowlby, R., Brooks, D., Thiessen, N., Coarfa, C., Ma, Y., Moore, R. A. & 8 others, Schein, J. E., Mungall, A. J., Liu, J., Pecot, C. V., Sood, A. K., Jones, S. J. M., Marra, M. A. & Gunaratne, P. H., 2016, In: OncoTarget. 7, 18, p. 25930-25948 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Significance of calcium binding, tyrosine phosphorylation, and lysine trimethylation for the essential function of calmodulin in vertebrate cells analyzed in a novel gene replacement system

    Panina, S., Stephan, A., la Cour, J. M., Jacobsen, K., Kallerup, L. K., Bumbuleviciute, R., Knudsen, K. V. K., Sanchez-Gonzalez, P., Villalobo, A., Olesen, U. H. & Berchtold, Martin Werner, 2012, In: Journal of Biological Chemistry. 287, 22, p. 18173-18181 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    3-methylcholanthrene induces differential recruitment of aryl hydrocarbon receptor to human promoters

    Pansoy, A., Ahmed, S., Valen, E., Sandelin, Albin Gustav & Matthews, J., 2010, In: Toxicological Sciences. 117, 1, p. 90-100 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    New families of human regulatory RNA structures identified by comparative analysis of vertebrate genomes.

    Parker, B. J., Moltke, Ida, Roth, A., Washietl, S., Wen, J., Kellis, M., Breaker, R. & Pedersen, Jakob Skou, 2011, In: Genome Research. 21, 11, p. 1929-1943 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    m6A modification of U6 snRNA modulates usage of two major classes of pre-mRNA 5' splice site

    Parker, M. T., Soanes, B. K., Kusakina, J., Larrieu, A., Knop, K., Joy, N., Breidenbach, F., Sherwood, Anna, Barton, G. J., Fica, S. M., Davies, B. H. & Simpson, G. G., 2022, In: eLife. 11, 34 p., 78808.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Radiation and speciation of pelagic organisms during periods of global warming: the case of the common minke whale, Balaenoptera acutorostrata

    Pastene, L. A., Goto, M., Kanda, N., Zerbini, A. N., Kerem, D., Watanabe, K., Bessho, Y., Hasegawa, M., Nielsen, Rasmus, Larsen, F. & Palsbøll, P. J., 2007, In: Molecular Ecology. 16, 7, p. 1481-1495 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer

    Pastuzyn, E. D., Day, C. E., Kearns, R. B., Kyrke-Smith, M., Taibi, A. V., McCormick, J., Yoder, N., Belnap, D. M., qrc243, qrc243, Morado, D. R., Briggs, J. A. G., Feschotte, C. & Shepherd, J. D., 2018, In: Cell. 172, 1-2, p. 275-288, E18 33 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    MiR-492 impairs the angiogenic potential of endothelial cells

    Patella, F., Leucci, E., Evangelista, M., Parker, B., Wen, J., Mercatanti, A., Rizzo, M., Chiavacci, E., Lund, Anders H. & Rainaldi, G., Aug 2013, In: Journal of Cellular and Molecular Medicine. 17, 8, p. 1006-15 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Systematic identification of long noncoding RNAs expressed during zebrafish embryogenesis

    Pauli, A., Valen, E., Lin, M. F., Garber, M., Vastenhouw, N. L., Levin, J. Z., Fan, L., Sandelin, Albin Gustav, Rinn, J. L., Regev, A. & Schier, A. F., 2012, In: Genome Research. 22, p. 577-591 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Diversity of nature's assembly lines - recent discoveries in non-ribosomal peptide synthesis

    Payne, J. A. E., Schoppet, M., Hansen, M. H. & Cryle, M. J., 2017, In: Molecular BioSystems. 13, 1, p. 9-22 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Monitoring of species’ genetic diversity in Europe varies greatly and overlooks potential climate change impacts

    Pearman, P. B., Broennimann, O., Aavik, T., Albayrak, T., Alves, P. C., Aravanopoulos, F. A., Bertola, L. D., Biedrzycka, A., Buzan, E., Cubric-Curik, V., Djan, M., Fedorca, A., Fuentes-Pardo, A. P., Fussi, B., Godoy, J. A., Gugerli, F., Hoban, S., Holderegger, R., Hvilsom, C., Iacolina, L. & 32 others, Kalamujic Stroil, B., Klinga, P., Konopiński, M. K., Kopatz, A., Laikre, L., Lopes-Fernandes, M., McMahon, B. J., Mergeay, J., Neophytou, C., Pálsson, S., Paz-Vinas, I., Posledovich, D., Primmer, C. R., Raeymaekers, J. A. M., Rinkevich, B., Rolečková, B., Ruņģis, D., Schuerz, L., Segelbacher, G., Kavčič Sonnenschein, K., Stefanovic, M., Thurfjell, H., Träger, S., Tsvetkov, I. N., Velickovic, N., Vergeer, P., Vernesi, C., Vilà, C., Westergren, M., Zachos, F. E., Guisan, A. & Bruford, M., 2024, In: Nature Ecology and Evolution. 8, p. 267–281 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Mammuthus sp. (Early and Middle Pleistocene Mammoths)

    Chrzanová Pecnerová, Patrícia, Díez-del-Molino, D., van der Valk, T., Dehasque, M., Götherström, A. & Dalén, L., 2021, In: Trends in Genetics. 37, 7, p. 682-683 2 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  67. Published

    A southern African origin and cryptic structure in the highly mobile plains zebra

    Pedersen, C. T., Albrechtsen, Anders, Etter, P. D., Johnson, E. A., Orlando, L., Chikhi, L., Siegismund, Hans Redlef & Heller, Rasmus, 2018, In: Nature Ecology & Evolution. 2, 3, p. 491-498 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Time clustered sampling can inflate the inferred substitution rate in foot-and-mouth disease virus analyses

    Pedersen, C. T., Frandsen, P., Wekesa, S. N., Heller, Rasmus, Sangula, A. K., Wadsworth, J., Knowles, N. J., Muwanika, V. B. & Siegismund, Hans Redlef, 2015, In: PLOS ONE. 10, 12, 13 p., e0143605.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    The effect of an extreme and prolonged population bottleneck on patterns of deleterious variation: insights from the Greenlandic Inuit

    Pedersen, C. T., Lohmueller, K. E., Grarup, Niels, Bjerregaard, P., Hansen, Torben, Siegismund, Hans Redlef, Moltke, Ida & Albrechtsen, Anders, Feb 2017, In: Genetics. 205, 2, p. 787-801 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Demographic inferences from large-scale NGS data

    Pedersen, C. T., 2017, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  71. Published

    Replication Protein A (RPA) Mediates Radio-Resistance of Glioblastoma Cancer Stem-Like Cells

    Pedersen, H., Obara, E. A. A., Elbæk, K. J., Vitting-Serup, K. & Hamerlik, P., 2020, In: International Journal of Molecular Sciences. 21, 5, 13 p., 1588.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Genome-wide nucleosome map and cytosine methylation levels of an ancient human genome

    Pedersen, J. S., Valen, E., Velazquez, A. M. V., Parker, B. J., Rasmussen, M., Lindgreen, S., Lilje, B., Tobin, D. J., Kelly, T. K., Vang, S., Andersson, R., Jones, P. A., Hoover, C. A., Tikhonov, A., Prokhortchouk, E., Rubin, E. M., Sandelin, A. G., Gilbert, M. T. P., Krogh, A., Willerslev, E. & 1 others, Orlando, L. A. A., 2014, In: Genome Research. 24, 3, p. 454-466 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Inflammatory pathways of importance for management of inflammatory bowel disease

    Pedersen, J., Coskun, M., Soendergaard, C., Salem, M. & Nielsen, Ole Haagen, 7 Jan 2014, In: World Journal of Gastroenterology. 20, 1, p. 64-77 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Inhibitors of apoptosis (IAPs) regulate intestinal immunity and inflammatory bowel disease (IBD) inflammation

    Pedersen, J., LaCasse, E. C., Seidelin, Jakob Benedict, Coskun, M. & Nielsen, Ole Haagen, Nov 2014, In: Trends in Molecular Medicine. 20, 11, p. 652-65 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Prey diversity is affected by climate and differs between age classes in the Red-backed Shrike (Lanius collurio)

    Pedersen, L., Geertsma, M. & Tøttrup, Anders P., 2012, In: Ornis Fennica. 89, 2, p. 99-108 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Biological systems on a small scale

    Pedersen, L., 2012, Center for Ice & Climate: Faculty of Science, University of Copenhagen. 184 p.

    Research output: Book/Report › Ph.D. thesis › Research

  77. Published

    A kinetic model explains why shorter and less affine enzyme-recruiting oligonucleotides can be more potent

    Pedersen, L., Hagedorn, P. H., Lindholm, M. W. & Lindow, M., 2014, In: Molecular Therapy - Nucleic Acids. 3, 8 p., e149.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Postglacial viability and colonization in North America’s ice-free corridor

    Pedersen, Mikkel Winther, Ruter, Anthony Henry, Schweger, C., Friebe, H., Staff, R. A., Kjeldsen, Kristian Kjellerup, Zepeda Mendoza, M. L., Beaudoin, A. B., Zutter, C., Larsen, Nicolaj Krog, Potter, B. A., Nielsen, Rasmus, Rainville, R. A., Orlando, L. A. A., Meltzer, D. J., Kjær, Kurt H. & Willerslev, Eske, 2016, In: Nature. 537, 7618, p. 45–49 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    RNA sequencing of trigeminal ganglia in Rattus Norvegicus after glyceryl trinitrate infusion with relevance to migraine

    Pedersen, S. H., Sørensen, L. M., Ramachandran, R., Sibbesen, Jonas Andreas, Yakimov, V., Christensen, R. E., Hansen, Thomas Folkmann, Krogh, Anders, Olesen, Jes & Olesen, I. J., 2016, In: P L o S One. 11, 5, 13 p., e0155039.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Thermodynamics of heat-shock response. Bourke Arnvig K, Pedersen S, Sneppen K

    Pedersen, Steen, 2000, In: Physical Review Letters. p. Phys Rev Lett; 84: 3005-8. 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Fast Translation within the First 45 Codons Decreases mRNA Stability and Increases Premature Transcription Termination in E. coli

    Pedersen, Steen, Terkelsen, Thilde Bagger, Eriksen, M., Hauge, M. K., Lund, C. C., Sneppen, Kim & Mitarai, Namiko, 2019, In: Journal of Molecular Biology. 431, 6, p. 1088-1097 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Regulating retrotransposon activity through the use of alternative transcription start sites

    Persson, J., Steglich, B., Smialowska, A., Boyd, M., Lange, Jette Bornholdt, Andersson, Robin, Schurra, C., Arcangioli, B., Sandelin, Albin Gustav, Nielsen, Olaf & Ekwall, K., 2016, In: E M B O Reports. 17, 5, p. 753-768 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Pigments and proteins in green bacterial chlorosomes studied by matrix-assisted laser desorption ionization mass spectrometry

    Persson, S., Sönksen, C. P., Frigaard, Niels-Ulrik, Cox, R. P., Roepstorff, P. & Miller, M., 2000, In: European Journal of Biochemistry. 267, 2, p. 450-456 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Body fluid identification of blood, saliva and semen using second generation sequencing of micro-RNA

    Petersen, C. H., Hjort, B. B., Tvedebrink, T., Kielpinski, L. J., Vinther, Jeppe & Morling, Niels, 2013, In: Forensic Science International: Genetics Supplement Series. 4, 1, p. e204-5 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    RpoD promoters in Campylobacter jejuni exhibit a strong periodic signal instead of a -35 box

    Petersen, L., Larsen, T. S., Ussery, D. W., On, S. L. W. & Krogh, Anders, 2003, In: Journal of Molecular Biology. 326(5), p. 1361-1372

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Genome-wide and sister chromatid-resolved profiling of protein occupancy in replicated chromatin with ChOR-seq and SCAR-seq

    Petryk, N., Reveron-Gomez, Nazaret, González-Aguilera, C., Dalby, M., Andersson, Robin & Groth, Anja, 2021, In: Nature Protocols. 16, p. 4446-4493

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    MCM2 promotes symmetric inheritance of modified histones during DNA replication

    Petryk, N., Dalby, M., Wenger, Alice, Stromme, C. B., Strandsby, A., Andersson, Robin & Groth, Anja, 2018, In: Science. 361, 6409, p. 1389-1392 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    High genetic diversity and low differentiation reflect the ecological versatility of the African leopard

    Chrzanová Pecnerová, Patrícia, Garcia Erill, Genís, Liu, Xiaodong, Nursyifa, Casia, Waples, R. K., Santander, Cindy, Quinn, Liam James Elgaard, Frandsen, P., Meisner, Jonas, Stæger, Frederik Filip Vinggaard, Rasmussen, Malthe Sebro, Brüniche-Olsen, Anna, Jørgensen, C. H. F., Rodrigues da Fonseca, Rute Andreia, Siegismund, Hans Redlef, Albrechtsen, Anders, Heller, Rasmus, Moltke, Ida & Hanghøj, Kristian Ebbesen, 2021, In: Current Biology. 31, 9, p. 1862-1871, e1-e5

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Population genomics of the muskox' resilience in the near absence of genetic variation

    Pečnerová, P., Lord, E., Garcia-Erill, G., Hanghøj, K., Rasmussen, M. S., Meisner, J., Liu, X., van der Valk, T., Santander, C. G., Quinn, L., Lin, L., Liu, S., Carøe, C., Dalerum, F., Götherström, A., Måsviken, J., Vartanyan, S., Raundrup, K., Al-Chaer, A., Rasmussen, L. & 11 others, Hvilsom, C., Heide-Jørgensen, M. P., Sinding, Mikkel Holger Strander, Aastrup, P., Van Coeverden de Groot, P. J., Schmidt, N. M., Albrechtsen, Anders, Dalén, L., Heller, Rasmus, Moltke, Ida & Siegismund, Hans Redlef, 2024, In: Molecular Ecology. 33, 2, 25 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Transcriptional and epigenomic profiling identifies YAP signaling as a key regulator of intestinal epithelium maturation

    Pikkupeura, Laura Maarit, Bardini Bressan, Raul, Guiu, J., Chen, Y., Maimets, Martti, Mayer, Daniela, Schweiger, P. J., Hansen, Stine Lind, Maciag, Grzegorz Jerzy, Larsen, Hjalte List, Lõhmussaar, Kadi, Pedersen, M. T., Teves, Joji Marie Yap, Lange, Jette Bornholdt, Benes, V., Sandelin, Albin Gustav & Jensen, Kim Bak, 2023, In: Science Advances. 9, 28, 16 p., eadf9460.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    First estimates of genetic diversity for the highly endangered giant sable antelope using a set of 57 microsatellites

    Pinto, P. V., Lopes, S., Mourao, S., Baptista, S., Siegismund, Hans Redlef, Van Vuuren, B. J., Beja, P., Ferrand, N. & Godinho, R., 2015, In: European Journal of Wildlife Research. 61, 2, p. 313-317 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Precise integration of inducible transcriptional elements (PrIITE) enables absolute control of gene expression

    Pinto, R., Hansen, Lars, Hintze, John, Almeida, R., Larsen, S., Coskun, M., Davidsen, J., Mitchelmore, C., David, L., Troelsen, J. T. & Bennett, Eric Paul, 2017, In: Nucleic Acids Research. 45, 13, 15 p., e123.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Highly accessible AU-rich regions in 3' untranslated regions are hotspots for binding of regulatory factors

    Plass, M., Rasmussen, S. H. & Krogh, Anders, 14 Apr 2017, In: PLoS Computational Biology. 13, 4, 26 p., e1005460.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Approaches to link RNA secondary structures with splicing regulation

    Plass, M. & Eyras, E., 2014, Spliceosomal Pre-mRNA Splicing. Hertel, K. J. (ed.). Springer Science+Business Media, Vol. 1126. p. 341-356 16 p. (Methods in Molecular Biology, Vol. 1126).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  95. Published

    MicroRNA expression profiling of the porcine developing brain

    Podolska, A., Kaczkowski, B., Busk, P. K., Søkilde, R., Litman, T., Fredholm, Merete & Cirera, Susanna, 2011, In: P L o S One. 6, p. e14494 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    How the RNA isolation method can affect microRNA microarray results

    Podolska, A., Kaczkowski, B., Litman, Thomas, Fredholm, Merete & Cirera, Susanna, 2011, In: Acta Biochimica Polonica. 58, 4, p. 535-540 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Expression, purification and preliminary diffraction studies of PhnP

    Podzelinska, K., He, S., Soares, A., Zechel, D., Hove-Jensen, B. & Jia, Z., 2008, In: Acta Crystallographica. Section F : Structural Biology and Crystallization Communications. 64, Pt 6, p. 554-7 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Structure of PhnP: a phosphodiesterase of the carbon-phosphorous lyase pathway for phosphonate degradation

    Podzelinska, K., He, S., Wathier, M., Yakunin, A., Proudfoot, M., Hove-Jensen, B., Zechel, D. L. & Jia, Z., 2009, In: Journal of Biological Chemistry. 284, 25, p. 17216-17226

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Inference of historical changes in migration rate from the lengths of migrant tracts

    Pool, J. E. & Nielsen, Rasmus, 2009, In: Genetics. 181, 2, p. 711-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Functions of m6A-YTH modules in plants: Lessons from high-throughput sequencing analyses

    Porcelli, C., 2023, Department of Biology, Faculty of Science, University of Copenhagen. 178 p.

    Research output: Book/Report › Ph.D. thesis › Research

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