Computational and RNA Biology

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  1. Published

    Genomic insights into the conservation status of the world's last remaining Sumatran rhinoceros populations

    von Seth, J., Dussex, N., Diez-del-Molino, D., van der Valk, T., Kutschera, V. E., Kierczak, M., Steiner, C. C., Liu, S., Gilbert, M. T. P., Sinding, M-H. S., Prost, S., Guschanski, K., Nathan, S. K. S. S., Brace, S., Chan, Y. L., Wheat, C. W., Skoglund, P., Ryder, O. A., Goossens, B., Gotherstrom, A. & 1 others, Dalen, L., 2021, In: Nature Communications. 12, 1, 11 p., 2393.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Million-year-old DNA sheds light on the genomic history of mammoths

    van der Valk, T., Pečnerová, P., Díez-del-Molino, D., Bergström, A., Oppenheimer, J., Hartmann, S., Xenikoudakis, G., Thomas, J. A., Dehasque, M., Sağlıcan, E., Fidan, F. R., Barnes, I., Liu, S., Somel, M., Heintzman, P. D., Nikolskiy, P., Shapiro, B., Skoglund, P., Hofreiter, M., Lister, A. M. & 2 others, Götherström, A. & Dalén, L., 2021, In: Nature. 591, 7849, p. 265-269

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Evolutionary consequences of genomic deletions and insertions in the woolly mammoth genome

    van der Valk, T., Dehasque, M., Chacón-Duque, J. C., Oskolkov, N., Vartanyan, S., Heintzman, P. D., Chrzanová Pecnerová, Patrícia, Díez-del-Molino, D. & Dalén, L., 2022, In: iScience. 25, 8, 11 p., 104826.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Reduced chromatin accessibility correlates with resistance to Notch activation

    van den Ameele, J., Krautz, Robert, Cheetham, S. W., Donovan, A. P. A., Llorà-Batlle, O., Yakob, R. & Brand, A. H., 2022, In: Nature Communications. 13, 1, 10 p., 2210.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    A new class of genic nuclear RNA species in Arabidopsis

    van Wonterghem, M., Thieffry, A., Boyd, M., Lange, Jette Bornholdt & Brodersen, Peter, 2018, In: FEBS Letters. 592, 4, p. 631-643 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Non-Coding RNAs in Arabidopsis: Discovery of Nuclear ncRNAs from Body Methylated Genes and of miRNA Pathway Inhibition by Conserved, Bacterial Virulence Factor

    van Wonterghem, M., 2015, Department of Biology, Faculty of Science, University of Copenhagen. 109 p.

    Research output: Book/Report › Ph.D. thesis › Research

  7. Published

    Effect of alkaline treatment on bacteriochlorophyll a, quinones, and energy transfer in chlorosomes from Chlorobium tepidum and Chlorobium phaeobacteroides

    van Walree, C. A., Sakuragi, Y., Steensgaard, D. B., Bösinger, C. S., Frigaard, Niels-Ulrik, Cox, R. P., Holzwarth, A. R. & Miller, M., 1999, In: Photochemistry and Photobiology. 69, p. 322-328 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Estimation of the covariance structure from SNP allele frequencies

    van Waaij, J., Li, Z. & Wiuf, Carsten, 2022, In: Statistical Applications in Genetics and Molecular Biology. 21, 1, 20 p., 20220005.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Transcription factor expression is the main determinant of variability in gene co-activity

    van Duin, Lucas, Krautz, Robert, Rennie, Sarah & Andersson, Robin, 2023, In: Molecular Systems Biology. 19, 7, 17 p., e11392.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Deciphering regulatory mechanisms underlying gene co-activity

    van Duin, Lucas, 2023, Department of Biology, Faculty of Science, University of Copenhagen. 131 p.

    Research output: Book/Report › Ph.D. thesis › Research

  11. Published

    Genomic insights into early maritime adaptations in Western Patagonia

    jxb425, jxb425, Moreno Mayar, J. Víctor, Alfonso-Durruty, M., Morello, F., Vilar, M., Wells, S., Campos, P. & Willerslev, Eske, 2018, p. 64. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research

  12. Published

    An integrated expression atlas of miRNAs and their promoters in human and mouse

    de Rie, D., Abugessaisa, I., Alam, T., Arner, E., Arner, P., Ashoor, H., Åström, G., Babina, M., Bertin, N., Burroughs, A. M., Carlisle, A. J., Daub, C. O., Detmar, M., Deviatiiarov, R., Fort, A., Gebhard, C., Goldowitz, D., Guhl, S., Ha, T. J., Harshbarger, J. & 31 others, Hasegawa, A., Hashimoto, K., Herlyn, M., Heutink, P., Hitchens, K. J., Hon, C. C., Huang, E., Ishizu, Y., Kai, C., Kasukawa, T., Klinken, P., Lassmann, T., Lecellier, C., Lee, W., Lizio, M., Makeev, V., Mathelier, A., Medvedeva, Y. A., Mejhert, N., Mungall, C. J., Noma, S., Ohshima, M., Okada-Hatakeyama, M., Persson, H., Rizzu, P., Roudnicky, F., Sætrom, P., Sato, H., Vitting-Seerup, K., Sandelin, Albin Gustav & FANTOM Consortium, F. C., 21 Aug 2017, In: Nature Biotechnology. 35, 9, p. 872-878 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Chimpanzee genomic diversity reveals ancient admixture with bonobos

    de Manuel, M., Kuhlwilm, M., Frandsen, P., Sousa, V. C., Desai, T., Prado-Martinez, J., Hernandez-Rodriguez, J., Dupanloup, I., Lao, O., Hallast, P., Schmidt, J. M., Heredia-Genestar, J. M., Benazzo, A., Barbujani, G., Peter, B. M., Kuderna, L. F. K., Casals, F., Angedakin, S., Arandjelovic, M., Boesch, C. & 17 others, Kühl, H., Vigilant, L., Langergraber, K., Novembre, J., Gut, M., Gut, I., Navarro, A., Carlsen, F., Andrés, A. M., Siegismund, Hans Redlef, Scally, A., Excoffier, L., Tyler-Smith, C., Castellano, S., Xue, Y., Hvilsom, C. & Marques-Bonet, T., 2016, In: Science. 354, 6311, p. 477-481 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Combining methods for non-invasive fecal DNA enables whole genome and metagenomic analyses in wildlife biology

    de Flamingh, A., Ishida, Y., Chrzanová Pecnerová, Patrícia, Vilchis, S., Siegismund, Hans Redlef, van Aarde, R. J., Malhi, R. S. & Roca, A. L., 2023, In: Frontiers in Genetics. 13, 14 p., 1021004.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    A draft genome sequence of the elusive giant squid, Architeuthis dux

    da Fonseca, R. R., Couto, A., Machado, A. M., Brejova, B., Albertin, C. B., Silva, F., Gardner, P., Baril, T., Hayward, A., Campos, A., Ribeiro, Â. M., Barrio-Hernandez, I., Hoving, H-J., Tafur-Jimenez, R., Chu, C., Frazão, B., Petersen, B., Peñaloza, F., Musacchia, F., Alexander, G. C. & 24 others, Osório, H., Winkelmann, I., Simakov, O., Rasmussen, Simon, Rahman, M. Z., Pisani, D., Vinther, J., Jarvis, E., KU, thw266, Strugnell, J. M., Castro, L. F. C., Fedrigo, O., Patricio, M., Li, Q., Rocha, S., Antunes, A., Wu, Y., Ma, B., Sanges, R., Vinar, T., Blagoev, B., Sicheritz-Pontén, Thomas, Nielsen, Rasmus & Gilbert, M Thomas P, 2020, In: GigaScience. 9, 1, 12 p., giz152.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Consequences of breed formation on patterns of genomic diversity and differentiation: the case of highly diverse peripheral Iberian cattle

    Rodrigues da Fonseca, Rute Andreia, Urena, I., Afonso, S., Pires, A. E., Jørsboe, E., Chikhi, L. & Ginja, C., 2019, In: BMC Genomics. 20, p. 1-13 334.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    MicroRNAs and potential target interactions in psoriasis

    Zibert, J. R., Løvendorf, M. B., Litman, Thomas, Olsen, Jørgen, Kaczkowski, B. & Skov, Lone, 2010, In: Journal of Dermatological Science. 58, 3, p. 177-185 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Whole Genome Sequencing in the Evaluation of Fetal Structural Anomalies: A Parallel Test with Chromosomal Microarray Plus Whole Exome Sequencing

    Zhou, J., Yang, Z., Sun, J., Liu, L., Zhou, X., Liu, F., Xing, Y., Cui, S., Xiong, S., Liu, X., Yang, Y., Wei, X., Zou, G., Wang, Z., Wei, X., Wang, Y., Zhang, Y., Yan, S., Wu, F., Zeng, F. & 4 others, Wang, J., Duan, T., Peng, Z. & Sun, L., 2021, In: Genes. 12, 3, 14 p., 376.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Performance characterization of PCR-free whole genome sequencing for clinical diagnosis

    Zhou, G., Zhou, M., Zeng, F., Zhang, N., Sun, Y., Qiao, Z., Guo, X., Zhou, S., Yun, G., Xie, J., Wang, X., Liu, F., Fan, C., Wang, Y., Fang, Z., Tian, Z., Dai, W., Sun, J., Peng, Z. & Song, L., 2022, In: Medicine. 101, 10, 8 p., e28972.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    The origin of domestication genes in goats

    Zheng, Z., Wang, X., Li, M., Li, Y., Yang, Z., Wang, X., Pan, X., Gong, M., Zhang, Y., Guo, Y., Wang, Y., Liu, J., Cai, Y., Chen, Q., Okpeku, M., Colli, L., Cai, D., Wang, K., Huang, S., Sonstegard, T. S. & 16 others, Esmailizadeh, A., Zhang, W., Zhang, T., Xu, Y., Xu, N., Yang, Y., Han, J., Chen, L., Lesur, J., Daly, K. G., Bradley, D. G., Heller, Rasmus, KU, thw266, Wang, W., Chen, Y. & Jiang, Y., 2020, In: Science Advances. 6, 21, eaaz5216.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Comparison of In-Frame Deletion, Homology-Directed Repair, and Prime Editing-Based Correction of Duchenne Muscular Dystrophy Mutations

    Zhao, X., Qu, Kunli, Curci, B., Yang, H., Bolund, L., Lin, L. & Luo, Y., 2023, In: Biomolecules. 13, 5, 15 p., 870.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    GMD: measuring the distance between histograms with applications on high-throughput sequencing reads

    Zhao, X. & Sandelin, Albin Gustav, 2012, In: Bioinformatics. 28, 8, p. 1164-1165 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    On gene regulation in eukaryotes: computational approaches to decipher transcriptional regulation at genetic and epigenetic level

    Zhao, X., 2012, Department of Biology, Faculty of Science, University of Copenhagen. 170 p.

    Research output: Book/Report › Ph.D. thesis › Research

  24. Published

    Systematic clustering of transcription start site landscapes

    Zhao, X., Valen, E., Parker, B. J. & Sandelin, Albin Gustav, 2011, In: P L o S One. 6, 8, 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Two Novel α-Thalassemia Mutations CD 39 -C [Thr > Pro] and CD 109 ACC > CCC [Thr > Pro] Identified in Two Chinese Families: A Case Report

    Zhang, W., Han, X., Deng, J., Zhou, R., Du, X., Wu, C. & Li, M., 2023, In: Hemoglobin. 47, 4, 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    An investigation of the statistical power of neutrality tests based on comparative and population genetic data

    Zhai, W., Nielsen, Rasmus & Slatkin, M., 2009, In: Molecular Biology and Evolution. 26, 2, p. 273-83 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    DivA: detection of non-homologous and very divergent regions in protein sequence alignments

    Zepeda Mendoza, M. L., Nygaard, S. & Rodrigues da Fonseca, Rute Andreia, 2014, In: BMC Research Notes. 7, 806, 6 p., 806.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Current challenges in understanding the role of enhancers in disease

    Zaugg, J. B., Sahlén, P., Andersson, Robin, Alberich-Jorda, M., de Laat, W., Deplancke, B., Ferrer, J., Mandrup, S., Natoli, G., Plewczynski, D., Rada-Iglesias, A. & Spicuglia, S., 2022, In: Nature Structural and Molecular Biology. 29, 12, p. 1148-1158 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Unraveling the genetic basis of neurological diseases and thalassemia: the clinical utility of high throughput sequencing

    ZHANG, W., 2023, Department of Biology, Faculty of Science, University of Copenhagen. 117 p.

    Research output: Book/Report › Ph.D. thesis › Research

  30. Published

    Clinical application of high-throughput sequencing technology in prenatal screening and diagnosis of birth defects

    ZENG, F., 2022, Department of Biology, Faculty of Science, University of Copenhagen. 118 p.

    Research output: Book/Report › Ph.D. thesis › Research

  31. Published

    Single-cell transcriptomic landscape of the sheep rumen provides insights into physiological programming development and adaptation of digestive strategies

    Yuan, Y., Sun, D., Qin, T., Mao, S., Zhu, W., Yin, Y., Huang, J., Heller, Rasmus, Li, Z., Liu, J. & Qiu, Q., 2022, In: Zoological research. 43, 4, p. 634-647 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease

    Young, W. J., Haessler, J., Benjamins, J-W., Repetto, L., Yao, J., Isaacs, A., Harper, A. R., Ramirez, J., Garnier, S., van Duijvenboden, S., Baldassari, A. R., Concas, M. P., Duong, T., Foco, L., Isaksen, J. L., Mei, H., Noordam, R., Nursyifa, C., Richmond, A., Santolalla, M. L. & 74 others, Sitlani, C. M., Soroush, N., Thériault, S., Trompet, S., Aeschbacher, S., Ahmadizar, F., Alonso, A., Brody, J. A., Campbell, A., Correa, A., Darbar, D., De Luca, A., Deleuze, J., Ellervik, Christina, Fuchsberger, C., Goel, A., Grace, C., Guo, X., Hansen, Torben, Heckbert, S. R., Jackson, R. D., Kors, J. A., Lima-Costa, M. F., Linneberg, Allan René, Macfarlane, P. W., Morrison, A. C., Navarro, P., Porteous, D. J., Pramstaller, P. P., Reiner, A. P., Risch, L., Schotten, U., Shen, X., Sinagra, G., Soliman, E. Z., Stoll, M., Tarazona-Santos, E., Tinker, A., Trajanoska, K., Villard, E., Warren, H. R., Whitsel, E. A., Wiggins, K. L., Arking, D. E., Avery, C. L., Conen, D., Girotto, G., Grarup, Niels, Hayward, C., Jukema, J. W., Mook-Kanamori, D. O., Olesen, Morten Steen Salling, Padmanabhan, S., Psaty, B. M., Pattaro, C., Ribeiro, A. L. P., Rotter, J. I., Stricker, B. H., van der Harst, P., van Duijn, C. M., Verweij, N., Wilson, J. G., Orini, M., Charron, P., Watkins, H., Kooperberg, C., Lin, H. J., Wilson, J. F., Kanters, Jørgen K., Sotoodehnia, N., Mifsud, B., Lambiase, P. D., Tereshchenko, L. G. & Munroe, P. B., 14 Mar 2023, In: Nature Communications. 14, 1, 16 p., 1411.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    The frequent evolutionary birth and death of functional promoters in mouse and human

    Young, R. S., Hayashizaki, Y., Andersson, Robin, Sandelin, Albin Gustav, Kawaji, H., Itoh, M., Lassmann, T., Carninci, P., Bickmore, W. A., Forrest, A. R. & Taylor, M. S., 2015, In: Genome Research. 25, p. 1546-1557 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Sequencing of 50 human exomes reveals adaptation to high altitude

    Yi, X., Liang, Y., Huerta-Sanchez, E., Jin, X., Cuo, Z. X. P., Pool, J. E., Xu, X., Jiang, H., Vinckenbosch, N., Korneliussen, T. S., Zheng, H., Liu, T., He, W., Li, K., Luo, R., Nie, X., Wu, H., Zhao, M., Cao, H., Zou, J. & 50 others, Shan, Y., Li, S., Yang, Q., Asan, G., Ni, P., Tian, G., Xu, J., Liu, X., Jiang, T., Wu, R., Zhou, G., Tang, M., Qin, J., Wang, T., Feng, S., Li, G., Huasang, G., Luosang, J., Wang, W., Chen, F., Wang, Y., Zheng, X., Li, Z., Bianba, Z., Yang, G., Wang, X., Tang, S., Gao, G., Yong, C., Luo, Z., Gusang, L., Cao, Z., Zhang, Q., Ouyang, W., Ren, X., Liang, H., Zheng, H., Huang, Y., Li, J., Bolund, L., Kristiansen, Karsten, Li, Y., Zhang, Y., Zhang, X., Li, R., Li, S., Yang, H., Nielsen, Rasmus, Wang, J. & Wang, J., 2 Jul 2010, In: Science. 329, 5987, p. 75-8 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Cancer Cell Acid Adaptation Gene Expression Response is Correlated to Tumor-Specific Tissue Expression Profiles and Patient Survival

    Yao, Jiayi, Czaplinska, D., Ialchina, Renata, Schnipper, J., Liu, B., Sandelin, Albin Gustav & Pedersen, Stine Helene Falsig, 2020, In: Cancers. 12, 8, 27 p., 2183.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    In defense of statistical methods for detecting positive selection

    Yang, Z., Nielsen, Rasmus & Goldman, N., 2009, In: Proceedings of the National Academy of Science of the United States of America. 106, 36, p. E95

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Intact RNA structurome reveals mRNA structure-mediated regulation of miRNA cleavage in vivo

    Yang, M., Woolfenden, H. C., Zhang, Y., Fang, X., Liu, Q., Vigh, Maria Louisa, Cheema, J., Yang, X., Norris, M., Yu, S., Carbonell, A., Brodersen, Peter, Wang, J. & Ding, Y., 2020, In: Nucleic Acids Research. 48, 15, p. 8767-8781 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Integrating convolution and self-attention improves language model of human genome for interpreting non-coding regions at base-resolution

    YANG, Meng, Huang, L., Huang, H., Tang, H., Zhang, N., Yang, H., Wu, J. & Mu, F., 2022, In: Nucleic Acids Research. 50, 14, 19 p., e81.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    TrustGWAS: A full-process workflow for encrypted GWAS using multi-key homomorphic encryption and pseudorandom number perturbation

    YANG, Meng, Zhang, C., Wang, X., Liu, X., Li, S., Huang, J., Feng, Z., Sun, X., Chen, F., Yang, S., Ni, M., Li, L., Cao, Y. & Mu, F., 2022, In: Cell Systems. 13, 9, p. 752-767.e6 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Contrastive learning enables rapid mapping to multimodal single-cell atlas of multimillion scale

    YANG, Meng, Yang, Y., Xie, C., Ni, M., Liu, J., Yang, H., Mu, F. & Wang, J., 2022, In: Nature Machine Intelligence. 4, 8, p. 696-709 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques

    Yan, G., Zhang, G., Fang, X., Zhang, Y., Li, C., Ling, F., Cooper, D. N., Li, Q., Li, Y., van Gool, A. J., Du, H., Chen, J., Chen, R., Zhang, P., Huang, Z., Thompson, J. R., Meng, Y., Bai, Y., Wang, J., Zhuo, M. & 26 others, Wang, T., Huang, Y., Wei, L., Li, J., Wang, Z., Hu, H., Yang, P., Le, L., Stenson, P. D., Li, B., Liu, X., Ball, E. V., An, N., Huang, Q., Zhang, Y., Fan, W., Zhang, X., Li, Y., Wang, W., Katze, M. G., Su, B., Nielsen, Rasmus, Yang, H., Wang, J., Wang, X. & Wang, J., 2011, In: Nature Biotechnology. 29, 11, p. 1019-1023 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  42. Published

    Mountain gorilla genomes reveal the impact of long-term population decline and inbreeding

    Xue, Y., Prado-Martinez, J., Sudmant, P. H., Narasimhan, V., Ayub, Q., Szpak, M., Frandsen, P., Chen, Y., Yngvadottir, B., Cooper, D. N., de Manuel, M., Hernandez-Rodriguez, J., Lobon, I., Siegismund, H. R., Pagani, L., Quail, M. A., Hvilsom, C., Mudakikwa, A., Eichler, E. E., Cranfield, M. R. & 3 others, Marques-Bonet, T., Tyler-Smith, C. & Scally, A., 2015, In: Science (New York, N.Y.). 348, 6231, p. 242-245 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Resequencing 50 accessions of cultivated and wild rice yields markers for identifying agronomically important genes

    Xu, X., Liu, X., Ge, S., Jensen, J. D., Hu, F., Li, X., Dong, Y., Gutenkunst, R. N., Fang, L., Huang, L., Li, J., He, W., Zhang, G., Zheng, X., Zhang, F., Li, Y., Yu, C., Kristiansen, K., Zhang, X., Wang, J. & 5 others, Wright, M., McCouch, S., Nielsen, Rasmus, Wang, J. & Wang, W., 2012, In: Nature Biotechnology. 30, 1, p. 105-111 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Two novel truncating variants of the ASPM gene identified in a nonconsanguineous Chinese family associated with primary microcephaly

    Xu, S., Zhang, W., Zhou, R., Huang, H., Chen, W., Xiang, W., Liu, L. & Song, J., 2022, In: Clinical Dysmorphology. 31, 1, p. 1-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    An integrated gene catalog and over 10,000 metagenome-assembled genomes from the gastrointestinal microbiome of ruminants

    Xie, F., Jin, W., Si, H., Yuan, Y., Tao, Y., Liu, J., Wang, X., Yang, C., Li, Q., Yan, X., Lin, L., Jiang, Q., Zhang, L., Guo, C., Greening, C., Heller, R., Guan, L. L., Pope, P. B., Tan, Z., Zhu, W. & 4 others, Wang, M., Qiu, Q., Li, Z. & Mao, S., 2021, In: Microbiome. 9, 20 p., 137.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Enhancing CRISPR-Cas9 gRNA efficiency prediction by data integration and deep learning

    Xiang, X., Corsi, G. I., Anthon, C., Qu, K., Pan, X., Liang, X., Han, P., Dong, Z., Liu, L., Zhong, J., Ma, T., Wang, J., Zhang, X., Jiang, H., Xu, F., Liu, X., Xu, X., Wang, J., Yang, H., Bolund, L. & 4 others, Church, G. M., Lin, L., Gorodkin, Jan & Luo, Y., 2021, In: Nature Communications. 12, 1, 9 p., 3238.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Global dispersal and adaptive evolution of domestic cattle: a genomic perspective

    Xia, X., Qu, K., Wang, Y., Sinding, Mikkel Holger Strander, Wang, F., Hanif, Q., Ahmed, Z., Lenstra, J. A., Han, J., Lei, C. & Chen, N., 2023, In: Stress Biology. 3, 1, 13 p., 8.

    Research output: Contribution to journal › Review › Research › peer-review

  48. Published

    Complete resequencing of 40 genomes reveals domestication events and genes in silkworm (Bombyx)

    Xia, Q., Guo, Y., Zhang, Z., Li, D., Xuan, Z., Li, Z., Dai, F., Li, Y., Cheng, D., Li, R., Cheng, T., Jiang, T., Becquet, C., Xu, X., Liu, C., Zha, X., Fan, W., Lin, Y., Shen, Y., Jiang, L. & 38 others, Jensen, J., Hellmann, I., Tang, S., Zhao, P., Xu, H., Yu, C., Zhang, G., Li, J., Cao, J., Liu, S., He, N., Zhou, Y., Liu, H., Zhao, J., Ye, C., Du, Z., Pan, G., Zhao, A., Shao, H., Zeng, W., Wu, P., Li, C., Pan, M., Li, J., Yin, X., Li, D., Wang, J., Zheng, H., Wang, W., Zhang, X., Li, S., Yang, H., Lu, C., Nielsen, Rasmus, Zhou, Z., Wang, J., Xiang, Z. & Wang, J., 2009, In: Science. 326, 5951, p. 433-6 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Tumor suppressor ASXL1 is essential for the activation of INK4B expression in response to oncogene activity and anti-proliferative signals

    Wu, X., Bekker-Jensen, I. H., Christensen, J., Rasmussen, K. D., Sidoli, S., Qi, Y., Kong, Y., Wang, X., Cui, Y., Xiao, Z., Xu, G., Williams, K., Rappsilber, J., Sønderby, C. K., Winther, Ole, Jensen, O. N. & Helin, K., 2015, In: Cell Research. 25, p. 1205-1218 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Fbxl10/Kdm2b recruits polycomb repressive complex 1 to CpG islands and regulates H2A ubiquitylation

    Wu, X., Johansen, Jens Vilstrup & Helin, K., 28 Mar 2013, In: Molecular Cell. 49, 6, p. 1134-46 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    The RNA exosome shapes the expression of key protein-coding genes

    Wu, M., Karadoulama, Evdoxia, Lloret-llinares, M., Rouviere, J. O., Vaagensø, C. S., Moravec, M., Li, B., Wang, J., Wu, G., Gockert, M. A. M., Pelechano, V., Jensen, T. H. & Sandelin, Albin Gustav, 2020, In: Nucleic Acids Research. 48, 15, p. 8509-8528

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Investigation of the Impact of the RNA Exosome on Cellular Transcriptome and Function

    Wu, M., 2021, Department of Biology, Faculty of Science, University of Copenhagen. 154 p.

    Research output: Book/Report › Ph.D. thesis › Research

  53. Published

    Computational identification of signals predictive for nuclear RNA exosome degradation pathway targeting

    Wu, M., Schmid, M., Jensen, T. H. & Sandelin, Albin Gustav, 2022, In: NAR Genomics and Bioinformatics. 4, 3, 18 p., lqac071.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    A Two-Layered Targeting Mechanism Underlies Nuclear RNA Sorting by the Human Exosome

    Wu, G., Schmid, M., Rib, Leonor, Polak, P., Meola, N., Sandelin, Albin Gustav & Jensen, T. H., 2020, In: Cell Reports. 30, 7, p. 2387-2401, e1-e5

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Identification of physicochemical selective pressure on protein encoding nucleotide sequences

    Wong, W. S. W., Sainudiin, R. & Nielsen, Rasmus, 2006, In: BMC Bioinformatics. 7, 10 p., 148.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Technical Considerations for Transcatheter Aortic Valve Replacement With the Navitor Transcatheter Heart Valve

    Wong, I., Bajoras, V., Wang, X., Bieliauskas, G., De Backer, Ole & Søndergaard, Lars, 2021, In: JACC: Cardiovascular Interventions. 14, 19, p. e259-e261

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    An evolutionary method for learning HMM structure: prediction of protein secondary structure.

    Won, K., Hamelryck, Thomas Wim, Prügel-Bennett, A. & Krogh, Anders, 2007, In: BMC Bioinformatics. 8, p. 357

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Evolving hidden Markov models for protein secondary structure prediction

    Won, K. J., Hamelryck, Thomas Wim, Prügel-Bennett, A. & Krogh, Anders, 2005, The 2005 IEEE Congress on Evolutionary Computation, IEEE CEC 2005: Proceedings. IEEE, Vol. 3. p. 33-40 8 p.

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

  59. Published

    The Block Hidden Markov Model for Biological Sequence Analysis

    Won, K. J., Prügel-Bennett, A. & Krogh, Anders, 2004, Knowledge-BasedIntelligent Informationand Engineering Systems: 8th International Conference, KES 2004, Proceedings. Negoita, M. G., Howlett, R. J. & Jain, L. (eds.). Springer, Vol. 1. p. 64-70 7 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), Vol. 3213).

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

  60. Published

    Training HMM structure with genetic algorithm for biological sequence analysis

    Won, K. J. & Krogh, Anders, 2004, In: Bioinformatics. Vol. 20 (18), p. 3613-9

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Discovering novel hydrolases from hot environments

    Wohlgemuth, R., Littlechild, J., Monti, D., Schnorr, K., van Rossum, T., Siebers, B., Menzel, P., Kublanov, I. V., Rike, A. G., Skretas, G., Szabo, Z., Peng, Xu & Young, M. J., 2018, In: Biotechnology Advances. 36, 8, p. 2077-2100

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Editorial: Long-read sequencing—Pitfalls, benefits and success stories

    Wohlers, I., Garg, S. & Hehir-Kwa, J. Y., 2023, In: Frontiers in Genetics. 13, 3 p., 1114542.

    Research output: Contribution to journal › Editorial › Research › peer-review

  63. Published

    Teaching computers to fold proteins

    Winther, O. & Krogh, Anders, 2004, In: Physical Review E (Statistical, Nonlinear, and Soft Matter Physics). Vol. 70 (3) pt. 1, p. 030903

    Research output: Contribution to journal › Journal article › Research

  64. Published

    Oral health status in historic population: Macroscopic and metagenomic evidence

    Willmann, C., Mata, X., Hanghøj, Kristian Ebbesen, Tonasso, L., Tisseyre, L., Jeziorski, C., Cabot, E., Chevet, P., Crubézy, E., Orlando, L., Esclassan, R., Thèves, C. & Caramelli, D., 2018, In: PLOS ONE. 13, 5, 18 p., e0196482.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Physiological responses of narwhals to anthropogenic noise: A case study with seismic airguns and vessel traffic in the Arctic

    Williams, T. M., Blackwell, S. B., Tervo, O., Garde, E., Sinding, Mikkel Holger Strander, Richter, B. & Heide-Jørgensen, M. P., 2022, In: Functional Ecology. 36, 9, p. 2251-2266 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    TGIF1 is a negative regulator of MLL-rearranged acute myeloid leukemia

    Willer, A., Jakobsen, J. S., Ohlsson, E., Rapin, N., Waage, J., Billing, M., Bullinger, L., Karlsson, S. & Porse, Bo Torben, 2015, In: Leukemia. 29, p. 1018-31 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Om kvalitet i forskningen.

    Willemoës, Martin, 1999, In: Biozoom. 3

    Research output: Contribution to journal › Comment/debate › Research

  68. Published

    Forskningsbaseret undervisning- og hva' så!

    Willemoës, Martin & Vogel, U. B., 2007, In: Biozoom. 3

    Research output: Contribution to journal › Comment/debate › Research

  69. Published

    Steady State Kinetic Model for the Binding of Substrates and Allosteric Effectors to Escherichia coli Phosphoribosyl-diphosphate Synthase.

    Willemoës, Martin, Hove-Jensen, B. & Larsen, Sine, 2000, In: Journal of Biological Chemistry. 45, p. 35408-35412

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Combined transcriptomic and proteomic analysis of the posterior salivary gland from the southern blue-ringed octopus and the southern sand octopus

    Whitelaw, B. L., Strugnell, J. M., Faou, P., Rodrigues da Fonseca, Rute Andreia, Hall, N. E., Norman, M., Finn, J. & Cooke, I. R., 2016, In: Journal of Proteome Research. 15, 9, p. 3284-3297 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Hyena paleogenomes reveal a complex evolutionary history of cross-continental gene flow between spotted and cave hyena

    Westbury, Michael Vincent, Hartmann, S., Barlow, A., Preick, M., Ridush, B., Nagel, D., Rathgeber, T., Ziegler, R., Baryshnikov, G., Sheng, G., Ludwig, A., Wiesel, I., Dalen, L., Bibi, F., Werdelin, L., Heller, Rasmus & Hofreiter, M., 2020, In: Science Advances. 6, 11, 11 p., eaay0456.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Symmetric inheritance of parental histones governs epigenome maintenance and embryonic stem cell identity

    Wenger, Alice, Biran, Alva Ada, Alcaraz, N., Redó-Riveiro, A., Sell, Annika Charlotte, Krautz, Robert, Flury, Valentin, Reveron-Gomez, Nazaret, Solis-Mezarino, V., Völker-Albert, M., Imhof, A., Andersson, Robin, Brickman, Joshua Mark & Groth, Anja, 2023, In: Nature Genetics. 55, 9, p. 1567-1578 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    VeTra: a tool for trajectory inference based on RNA velocity

    Weng, Guangzheng, Kim, Junil & Won, K. J., 2021, In: Bioinformatics. 37, 20, p. 3509-3513 btab364.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Transcriptome dynamics of the microRNA inhibition response

    Wen, J., Leucci, E., Vendramin, R., Kauppinen, S., Lund, Anders H., Krogh, Anders & Parker, B. J., 2015, In: Nucleic Acids Research. 43, 13, p. 6207-6221 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    MicroRNA transfection and AGO-bound CLIP-seq data sets reveal distinct determinants of miRNA action

    Wen, J., Parker, B. J., Jacobsen, A. & Krogh, Anders, 2011, In: R N A. 17, 5, p. 820-34 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Genetic diversity of serotype A foot-and-mouth disease viruses in Kenya from 1964 to 2013; implications for control strategies in eastern Africa

    Wekesa, S. N., Sangula, A. K., Belsham, G., Muwanika, V. B., Heller, Rasmus, Balinda, S. N., Masembe, C. & Siegismund, Hans Redlef, 2014, In: Infection, Genetics and Evolution. 21, p. 408-417 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Characterisation of recent foot-and-mouth disease viruses from African buffalo ( Syncerus caffer ) and cattle in Kenya is consistent with independent virus populations

    Wekesa, S., Sangula, A., Belsham, G. J., Tjornehoj, K., Muwanika, V. B., Gakuya, F., Mijele, D. & Siegismund, Hans Redlef, 2015, In: B M C Veterinary Research. 11, 17.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Analysis of recent serotype O foot-and-mouth disease viruses from Livestock in Kenya: evidence of four independently evolving lineages

    Wekesa, S. N., Muwanika, V. B., Siegismund, Hans Redlef, Sangula, A. K., Namatovu, A., Dhikusooka, M. T., Tjørnehøj, K., Balinda, S. N., Wadsworth, J., Knowles, N. J. & Belsham, G. J., 2015, In: Transboundary and Emerging Diseases. 62, 3, p. 305-314 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Mammalian tissues defective in nonsense-mediated mRNA decay display highly aberrant splicing patterns

    Weischenfeldt, Joachim Lütken, Waage, J. E., Tian, G., Zhao, J., Damgaard, I., Jakobsen, J. S., Kristiansen, Karsten, Krogh, Anders, Wang, J. & Porse, Bo Torben, 2012, In: Genome Biology (Online Edition). 13, 5, 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Genome-wide analysis of noncoding regulatory mutations in cancer

    Weinhold, N., Skanderup, A. M. J., Schultz, N., Sander, C. & Lee, W., 2014, In: Nature Genetics. 46, 11, p. 1160-1165 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Limited genetic variations of the Rh5-CyRPA-Ripr invasion complex in Plasmodium falciparum parasite population in selected malaria-endemic regions, Kenya

    Waweru, H., Kanoi, B. N., Kuja, J. O., Maranga, M., Kongere, J., Maina, M., Kinyua, J. & Gitaka, J., 2023, In: Frontiers in Tropical Diseases. 4, 9 p., 1102265.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Allele frequency-free inference of close familial relationships from genotypes or low-depth sequencing data

    Waples, R. K., Albrechtsen, Anders & Moltke, Ida, 2019, In: Molecular Ecology. 28, 1, p. 35-48 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    The genetic history of Greenlandic-European contact

    Waples, R. K., Hauptmann, A. L., Seiding, I. H., Jørsboe, E., Jørgensen, M. E., Grarup, Niels, Andersen, M. K., Larsen, C. V. L., Bjerregaard, P., Hellenthal, G., Hansen, Torben, Albrechtsen, Anders & Moltke, Ida, 2021, In: Current Biology. 31, 10, p. 2214-2219.e4

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Relatedness, admixture and the genetic history of Greenland-European contact

    Waples, R., 2019, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  85. Published

    Pseudoreplication in genomics-scale data sets

    Waples, R. S., Waples, R. K. & Ward, E. J., 2022, In: Molecular Ecology Resources. 22, 2, p. 503-518 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Genetic basis of ruminant headgear and rapid antler regeneration

    Wang, Y., Zhang, C., Wang, N., Li, Z., Heller, R., Liu, R., Zhao, Y., Han, J., Pan, X., Zheng, Z., Dai, X., Chen, C., Dou, M., Peng, S., Chen, X., Liu, J., Li, M., Wang, K., Liu, C., Lin, Z. & 18 others, Chen, L., Hao, F., Zhu, W., Song, C., Zhao, C., Zheng, C., Wang, J., Hu, S., Li, C., Yang, H., Jiang, L., Li, G., Liu, M., Sonstegard, T. S., KU, thw266, Jiang, Y., Wang, W. & Qiu, Q., 2019, In: Science. 364, 6446, p. 1153-+ eaav6335.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    DeepLocRNA: an interpretable deep learning model for predicting RNA subcellular localization with domain-specific transfer-learning

    Wang, Jun, Horlacher, M., Cheng, L. & Winther, Ole, 2024, In: Bioinformatics. 40, 2, 10 p., btae065.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    The diploid genome sequence of an Asian individual

    Wang, J., Wang, W., Li, R., Li, Y., Tian, G., Goodman, L., Fan, W., Zhang, J., Li, J., Zhang, J., Guo, Y., Feng, B., Li, H., Lu, Y., Fang, X., Liang, H., Du, Z., Li, D., Zhao, Y., Hu, Y. & 57 others, Yang, Z., Zheng, H., Hellmann, I., Inouye, M., Pool, J., Yi, X., Zhao, J., Duan, J., Zhou, Y., Qin, J., Ma, L., Li, G., Yang, Z., Zhang, G., Yang, B., Yu, C., Liang, F., Li, W., Li, S., Li, D., Ni, P., Ruan, J., Li, Q., Zhu, H., Liu, D., Lu, Z., Li, N., Guo, G., Zhang, J., Ye, J., Fang, L., Hao, Q., Chen, Q., Liang, Y., Su, Y., San, A., Ping, C., Yang, S., Chen, F., Li, L., Zhou, K., Zheng, H., Ren, Y., Yang, L., Gao, Y., Yang, G., Li, Z., Feng, X., Kristiansen, Karsten, Wong, G. K., Nielsen, Rasmus, Durbin, R., Bolund, L., Zhang, X., Li, S., Yang, H. & Wang, J., 2008, In: Nature. 456, 7218, p. 60-65 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    RNA trafficking and subcellular localization—a review of mechanisms, experimental and predictive methodologies

    Wang, Jun, Horlacher, M., Cheng, L. & Winther, Ole, 2023, In: Briefings in Bioinformatics. 24, 5, 14 p., bbad249.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    The Draft Genome of Red Lechwe, Kobus leche leche

    Wang, B., Wang, Z., Zhou, J., Liu, W., Lin, Z., Zhang, C., Liu, G., Zhou, B., Wan, W., Zhao, R., Wang, W., Heller, Rasmus & Chen, L., 2020, In: Frontiers in Genetics. 11, 7 p., 582638.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Genetics of early-life head circumference and genetic correlations with neurological, psychiatric and cognitive outcomes

    Vogelezang, S., Bradfield, J. P., Early Growth Genetics Consortium, Ahluwalia, T. V. S., Liu, X., Schnurr, T. M., Frithioff-Bøjsøe, C., Bønnelykke, K., Lind, M. V., Lauritzen, L., Michaelsen, K. F., Lund, M. A. V., Melbye, M., Morgen, C. S., Pedersen, O. B., Holm, J-C., Grarup, N., Hansen, T., Nohr, E. A., Bisgaard, H. & 3 others, Grant, S. F. A., Felix, J. F. & Jaddoe, V. W. V., 2022, In: BMC Medical Genomics. 15, 16 p., 124.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Niels Bohr – er det ikke noget med nogen antomer? Personer og kanoner i naturvidenskaben.

    Vogel, U. B. & Willemoës, Martin, 2006, In: Biozoom. 1

    Research output: Contribution to journal › Comment/debate › Research

  93. Published

    Transcriptional diversity and regulation across time and states

    Vitting-Seerup, K., 2016, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  94. Published

    spliceR: an R package for classification of alternative splicing and prediction of coding potential from RNA-seq data

    Vitting-Seerup, K., Porse, Bo Torben, Sandelin, Albin Gustav & Waage, J., 2014, In: B M C Bioinformatics. 15, p. 1-7 7 p., 81.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    The landscape of isoform switches in human cancers

    Vitting-Seerup, K. & Sandelin, Albin Gustav, Sep 2017, In: Molecular Cancer Research. 15, 9, p. 1206-1220 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    IsoformSwitchAnalyzeR: analysis of changes in genome-wide patterns of alternative splicing and its functional consequences

    Vitting-Seerup, K. & Sandelin, Albin Gustav, 2019, In: Bioinformatics. 35, 21, p. 4469-4471

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    CAGE-defined promoter regions of the genes implicated in Rett Syndrome

    Vitezic, M., Bertin, N., Andersson, Robin, Lipovich, L., Kawaji, H., Lassmann, T., Sandelin, Albin Gustav, Heutink, P., Goldowitz, D., Ha, T., Zhang, P., Patrizi, A., Fagiolini, M., Forrest, A. R., Carninci, P. & Saxena, A., 2014, In: BMC Genomics. 15, 16 p., 1177.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    No Evidence for N7-Methylation of Guanosine (m7G) in Human let-7e

    Vinther, Jeppe, 2020, In: Molecular Cell. 79, 2, p. 199-200 2 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  99. Published

    Comment on “DpCoA tagSeq: Barcoding dpCoA-Capped RNA for Direct Nanopore Sequencing via Maleimide-Thiol Reaction”

    Vinther, Jeppe, 2024, In: Analytical Chemistry. 96, 1, p. 606-609 4 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  100. Published

    MicroRNAs and Their Antagonists as Novel Therapeutics

    Vinther, Jeppe, Rukov, J. & Shomron, N., 2012, From Nucleic Acids Sequences to Molecular Medicine. Erdmann, V. A. & Barciszewski, J. (eds.). Springer Publishing Company, p. 503-523 21 p. (RNA Technologies).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

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