- Published
The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2022 update
Afgan, E., Nekrutenko, A., Grüning, B. A., Blankenberg, D., Goecks, J., Schatz, M. C., Ostrovsky, A. E., Mahmoud, A., Lonie, A. J., Syme, A., Fouilloux, A., Bretaudeau, A., Nekrutenko, A., Kumar, A., Eschenlauer, A. C., Desanto, A. D., Guerler, A., Serrano-Solano, B., Batut, B., Grüning, B. A. & 85 others, , 2022, In: Nucleic Acids Research. 50, W1, p. W345-W351 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes
Sparsø, T., Andersen, G., Nielsen, T., Burgdorf, K. S., Gjesing, A. M. P., Nielsen, A. L., Albrechtsen, Anders, Rasmussen, S. S., Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Madsbad, Sten, Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Diabetologia. 51, 1, p. 70-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The GBAF chromatin remodeling complex binds H3K27ac and mediates enhancer transcription
Jefimov, K., Alcaraz, N., Kloet, S. L., Värv, S., Sakya, S. A., Vaagenso, C., Vermeulen, M., Aasland, R. & Andersson, Robin, 2018, 31 p.Research output: Working paper › Preprint
- Published
The Draft Genome of Red Lechwe, Kobus leche leche
Wang, B., Wang, Z., Zhou, J., Liu, W., Lin, Z., Zhang, C., Liu, G., Zhou, B., Wan, W., Zhao, R., Wang, W., Heller, Rasmus & Chen, L., 2020, In: Frontiers in Genetics. 11, 7 p., 582638.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Block Hidden Markov Model for Biological Sequence Analysis
Won, K. J., Prügel-Bennett, A. & Krogh, Anders, 2004, Knowledge-BasedIntelligent Informationand Engineering Systems: 8th International Conference, KES 2004, Proceedings. Negoita, M. G., Howlett, R. J. & Jain, L. (eds.). Springer, Vol. 1. p. 64-70 7 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), Vol. 3213).Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
- Published
The Bipolar Illness Onset study: research protocol for the BIO cohort study
Kessing, Lars Vedel, Munkholm, K., Faurholt-Jepsen, M., Miskowiak, Kamilla, Nielsen, L. B., Frikke-Schmidt, Ruth, Ekstrøm, Claus Thorn, Winther, Ole, Pedersen, Bente Klarlund, Poulsen, Henrik Enghusen, McIntyre, R. S., Kapczinski, F., Gattaz, W. F., Bardram, J., Frost, M., Mayora, O., Knudsen, Gitte Moos, Phillips, M. & Vinberg, Maj, 2017, In: BMJ Open. 7, 6, 12 p., e015462.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The AIMe registry for artificial intelligence in biomedical research
Matschinske, J., Alcaraz, N., Benis, A., Golebiewski, M., Grimm, D. G., Heumos, L., Kacprowski, T., Lazareva, O., List, M., Louadi, Z., Pauling, J. K., Pfeifer, N., Röttger, R., Schwämmle, V., Sturm, G., Traverso, A., Van Steen, K., de Freitas, M. V., Villalba Silva, G. C., Wee, L. & 5 others, , 2021, In: Nature Methods. 18, 10, p. 1128-1131 4 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
The bchU gene of Chlorobium tepidum encodes the C-20 methyltransferase in bacteriochlorophyll c biosynthesis
Maresca, J. A., Gomez Maqueo Chew, A., Ponsatí, M. R., Frigaard, Niels-Ulrik, Ormerod, J. G. & Bryant, D. A., 2004, In: Journal of Bacteriology. 186, 9, p. 2558-2566 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The 4.5 S RNA gene of Escherichia coli is essential for cell growth
Brown, Stanley & Fournier, M. J., 1984, In: Journal of Molecular Biology. 178, 3, p. 533-50 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The -250G>A promoter variant in hepatic lipase associates with elevated fasting serum high-density lipoprotein cholesterol modulated by interaction with physical activity in a study of 16,156 Danish subjects
Grarup, N., Andreasen, C. H., Lepola, Mette Andersen, Albrechtsen, Anders, Sandbaek, A., Lauritzen, T., Borch-Johnsen, K., Jørgensen, T., Schmitz, O., Hansen, T. & Pedersen, Oluf Borbye, 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 6, p. 2294-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Testing parametric models in linear-directional regression
Garcia Portugues, E., van Keilegom, I., Crujeiras, R. M. & González-Manteiga, W., 2016, In: Scandinavian Journal of Statistics. 43, 4, p. 1178-1191 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Testing for Hardy-Weinberg equilibrium in structured populations using genotype or low-depth next generation sequencing data
Meisner, Jonas & Albrechtsen, Anders, 2019, In: Molecular Ecology Resources. 19, 5, p. 1144-1152 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Terminal Pleistocene Alaskan genome reveals first founding population of Native Americans
Moreno Mayar, J. Víctor, Potter, B. A., Vinner, Lasse, Steinrucken, M., Rasmussen, Simon, Terhorst, J., Kamm, J. A., Albrechtsen, Anders, Malaspinas, A., Sikora, Martin, Reuther, J. D., Irish, J. D., Malhi, R. S., Orlando, L. A. A., Song, Y. S., Nielsen, Rasmus, Meltzer, D. J. & Willerslev, Eske, 2018, In: Nature Genetics. 553, 7687, p. 203-207 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Temporal mapping of CEBPA and CEBPB binding during liver regeneration reveals dynamic occupancy and specific regulatory codes for homeostatic and cell cycle gene batteries
Jakobsen, J. S., Waage, J., Rapin, N., Bisgaard, Hanne Cathrine, Larsen, F. S. & Porse, Bo Torben, Apr 2013, In: Genome Research. 23, 4, p. 592-603 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy
Bruedigam, C., Bagger, F. O., Heidel, F. H., Kuhn, C. P., Guignes, S., Song, A., Austin, R., Vu, T., Lee, E., Riyat, S., Moore, A. S., Lock, R. B., Bullinger, L., Hill, G. R., Armstrong, S. A., Williams, D. A. & Lane, S. W., 2014, In: Cell Stem Cell. 15, 6, p. 775-790 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Technical Considerations for Transcatheter Aortic Valve Replacement With the Navitor Transcatheter Heart Valve
Wong, I., Bajoras, V., Wang, X., Bieliauskas, G., De Backer, Ole & Søndergaard, Lars, 2021, In: JACC: Cardiovascular Interventions. 14, 19, p. e259-e261Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Teaching computers to fold proteins
Winther, O. & Krogh, Anders, 2004, In: Physical Review E (Statistical, Nonlinear, and Soft Matter Physics). Vol. 70 (3) pt. 1, p. 030903Research output: Contribution to journal › Journal article › Research
- Published
Targets of balancing selection in the human genome
Andrés, A. M., Hubisz, M. J., Indap, A., Torgerson, D. G., Degenhardt, J. D., Boyko, A. R., Gutenkunst, R. N., White, T. J., Green, E. D., Bustamante, C. D., Clark, A. G. & Nielsen, Rasmus, 2009, In: Molecular Biology and Evolution. 26, 12, p. 2755-64 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeted next-generation sequencing analysis identifies novel mutations in families with severe familial exudative vitreoretinopathy
Huang, X., Zhuang, H., Wu, J., Li, J., Hu, F., Zheng, Y., Tellier, L. C. A. M., Zhang, S., Gao, F., Zhang, J. & Xu, G., 23 Aug 2017, In: Molecular Vision. 23, p. 605-613 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeted conservation genetics of the endangered chimpanzee
Frandsen, P., Fontsere, C., Nielsen, S. V., Hanghøj, Kristian Ebbesen, Castejon-Fernandez, N., Lizano, E., Hughes, D., Hernandez-Rodriguez, J., Korneliussen, Thorfinn Sand, Carlsen, F., Siegismund, Hans Redlef, Mailund, T., Marques-Bonet, T. & Hvilsom, C., 2020, In: Heredity. 125, 1-2, p. 15-27 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tanimoto's Best Barbecue: Discovering Regulatory Modules using Tanimoto Scores
Menzel, K. P., Mosig, A. & Stadler, P. F., 2007, Lecture Notes in Informatics: Proceedings of the German Conference on Bioinformatics 2007. Falter, C., Schliep, A., Selbig, J. & Walther, M. V. A. (eds.). p. 68-77 10 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
TGIF1 is a negative regulator of MLL-rearranged acute myeloid leukemia
Willer, A., Jakobsen, J. S., Ohlsson, E., Rapin, N., Waage, J., Billing, M., Bullinger, L., Karlsson, S. & Porse, Bo Torben, 2015, In: Leukemia. 29, p. 1018-31 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
T2DB: A Web Database for Long Non-Coding RNA Genes in Type II Diabetes
Distefano, R., Ilieva, M., Madsen, J. H., Ishii, H., Aikawa, M., Rennie, Sarah & Uchida, S., 2023, In: Non-coding RNA. 9, 3, 20 p., 30.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systematic review of machine learning for diagnosis and prognosis in dermatology
Thomsen, K., Iversen, L., Titlestad, T. L. & Winther, Ole, 2020, In: Journal of Dermatological Treatment. 31, 5, p. 496-510Research output: Contribution to journal › Review › Research › peer-review
- Published
Systematic identification of long noncoding RNAs expressed during zebrafish embryogenesis
Pauli, A., Valen, E., Lin, M. F., Garber, M., Vastenhouw, N. L., Levin, J. Z., Fan, L., Sandelin, Albin Gustav, Rinn, J. L., Regev, A. & Schier, A. F., 2012, In: Genome Research. 22, p. 577-591 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systematic clustering of transcription start site landscapes
Zhao, X., Valen, E., Parker, B. J. & Sandelin, Albin Gustav, 2011, In: P L o S One. 6, 8, 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systematic Analysis of Long Non-Coding RNAs in Inflammasome Activation in Monocytes/Macrophages
Qian, N., Distefano, R., Ilieva, M., Madsen, J. H., Rennie, Sarah & Uchida, S., 2023, In: Non-coding RNA. 9, 5, 16 p., 50.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Symmetric inheritance of parental histones governs epigenome maintenance and embryonic stem cell identity
Wenger, Alice, Biran, Alva Ada, Alcaraz, N., Redó-Riveiro, A., Sell, Annika Charlotte, Krautz, Robert, Flury, Valentin, Reveron-Gomez, Nazaret, Solis-Mezarino, V., Völker-Albert, M., Imhof, A., Andersson, Robin, Brickman, Joshua Mark & Groth, Anja, 2023, In: Nature Genetics. 55, 9, p. 1567-1578 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Surface exposed amino acid differences between mesophilic and thermophilic phosphoribosyl diphosphate synthase.
Hove-Jensen, B. & McGuire, J. N., 2004, In: European Journal of Biochemistry. 271, 22, p. 4526-33 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sulfur metabolism in phototrophic sulfur bacteria
Frigaard, Niels-Ulrik & Dahl, C., 2008, In: Advances in Microbial Physiology. 54, p. 103-200 97 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sugar metabolism of the first thermophilic Planctomycete Thermogutta terrifontis: comparative genomic and transcriptomic approaches
Elcheninov, A. G., Menzel, P., Gudbergsdottir, S. R., Slesarev, A. I., Kadnikov, V. V., Krogh, Anders, Bonch-Osmolovskaya, E. A., Peng, Xu & Kublanov, I. V., 2 Nov 2017, In: Frontiers in Microbiology. 8, 11 p., 2140.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subtle Monte Carlo updates in dense molecular systems
Bottaro, S., Boomsma, Wouter, Johansson, Kristoffer Enøe, Andreetta, C., Hamelryck, Thomas Wim & Ferkinghoff-Borg, J., 2012, In: Journal of Chemical Theory and Computation. 8, 2, p. 695-702 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subcellular localization of chlorosome proteins in Chlorobium tepidum and characterization of three new chlorosome proteins: CsmF, CsmH, and CsmX
Vassilieva, E. V., Stirewalt, V. L., Jakobs, C. U., Frigaard, Niels-Ulrik, Inoue-Sakamoto, K., Baker, M. A., Sotak, A. & Bryant, D. A., 2002, In: Biochemistry. 41, p. 4358-4370 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of the location and function of isoprenoid quinones in chlorosomes from green sulfur bacteria
Frigaard, Niels-Ulrik, Matsuura, K., Hirota, M., Miller, M. & Cox, R. P., 1998, In: Photosynthesis Research. 58, p. 81-90 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects
Grarup, Niels, Lepola, Mette Andersen, Andreasen, C. H., Albrechtsen, Anders, Borch-Johnsen, K., Jørgensen, T., Auwerx, J., Schmitz, O., Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 1, p. 363-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes
Johansson, E., Fanø, M., Bynck, J. H., Neuhard, J., Larsen, S., Sigurskjold, B. W., Christensen, U. & Willemoës, Martin, 2005, In: Journal of Biological Chemistry. 280, 4, p. 3051-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structures and Interactions of Proteins in the Brain: The Interaction Between LRP1 and Aß & Structure and Self-Assembly of Arc
Nielsen, L. D., 2017, Department of Biology, Faculty of Science, University of Copenhagen.Research output: Book/Report › Ph.D. thesis › Research
- Published
Structure of PhnP: a phosphodiesterase of the carbon-phosphorous lyase pathway for phosphonate degradation
Podzelinska, K., He, S., Wathier, M., Yakunin, A., Proudfoot, M., Hove-Jensen, B., Zechel, D. L. & Jia, Z., 2009, In: Journal of Biological Chemistry. 284, 25, p. 17216-17226Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure of Dihydroorotate Dehydrogenase B: Electron Transfer between Two Flavin Groups Bridged by an Iron-Sulphur Cluster
Rowland, P., Nørager, S., Jensen, K. F. & Larsen, Sine, 2000, In: Structure. 8, 12, p. 1227-1238Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural, kinetic, and mutational studies of the zinc ion environment in tetrameric cytidine deaminase
Johansson, E., Neuhard, J., Willemoës, Martin & Larsen, Sine, 2004, In: Biochemistry. 43, 20, p. 6020-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural profiles of human miRNA families from pairwise clustering
Kaczkowski, B., Þórarinsson, E., Reiche, K., Havgaard, Jakob Hull, Stadler, P. F. & Gorodkin, Jan, 2009, In: Bioinformatics. 25, 3, p. 291-294 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural and kinetic studies of the allosteric transition in Sulfolobus solfataricus uracil phosphoribosyltransferase: Permanent activation by engineering of the C-terminus
Christoffersen, S., Kadziola, Anders, Johansson, E., Rasmussen, M., Willemoës, Martin & Jensen, K. F., 2009, In: Journal of Molecular Biology. 393, 2, p. 464-477Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural and enzymatic investigation of the Sulfolobus solfataricus uridylate kinase shows competitive UTP inhibition and the lack of GTP stimulation.
Jensen, K. S., Johansson, E. & Jensen, K. F., 2007, In: Biochemistry. 46, 10, p. 2745-57 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Steady State Kinetic Model for the Binding of Substrates and Allosteric Effectors to Escherichia coli Phosphoribosyl-diphosphate Synthase.
Willemoës, Martin, Hove-Jensen, B. & Larsen, Sine, 2000, In: Journal of Biological Chemistry. 45, p. 35408-35412Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Statistics of bivariate von mises distributions
Mardia, K. V. & Frellsen, J., 2012, Bayesian methods in structural bioinformatics. Hamelryck, T., Mardia, K. & Ferkinghoff-Borg, J. (eds.). Springer, p. 159-178 20 p. (Statistics for Biology and Health).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Statistical inferences in phylogeography
Nielsen, Rasmus & Beaumont, M. A., 2009, In: Molecular Ecology. 18, 6, p. 1034-47 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Statistical inference of Identity-By-Descent sharing in human genomes and its applications in evolutionary and medical genetics
Moltke, Ida, 2011Research output: Book/Report › Ph.D. thesis › Research
- Published
Statistical assignment of DNA sequences using Bayesian phylogenetics
Terkelsen, K. M., Boomsma, Wouter, Huelsenbeck, J. P., Willerslev, Eske & Nielsen, Rasmus, 2008, In: Systematic Biology. 57, 5, p. 750-757 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Statistical Approaches Accomodating Uncertainty in Modern Genomic Data
Skotte, L., 2015, Department of Biology, Faculty of Science, University of Copenhagen.Research output: Book/Report › Ph.D. thesis › Research
- Published
Sphingosine-1-phosphate signaling in inflammatory bowel disease
Nielsen, Ole Haagen, Li, Yuan, Lindbom, B. J. & Coskun, M., Apr 2017, In: Trends in Molecular Medicine. 23, 4, p. 362-374 13 p.Research output: Contribution to journal › Review › Research › peer-review
Most downloads
-
6192
downloads
Reconstructing genome evolution in historic samples of the Irish potato famine pathogen
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
5492
downloads
Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
5254
downloads
True single-molecule DNA sequencing of a pleistocene horse bone
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Latest publications
Characterizing glucokinase variant mechanisms using a multiplexed abundance assay
Research output: Contribution to journal › Journal article › Research › peer-review
Genetic diversity of lion populations in Kenya: Evaluating past management practices and recommendations for future conservation actions
Research output: Contribution to journal › Journal article › Research › peer-review
MYC activity at enhancers drives prognostic transcriptional programs through an epigenetic switch
Research output: Contribution to journal › Journal article › Research › peer-review