- 2022
- Published
SignalP 6.0 predicts all five types of signal peptides using protein language models
Teufel, Felix Georg, Almagro Armenteros, J. J., Johansen, A. R., Gíslason, M. H., Pihl, S. I., Tsirigos, Konstantinos, Winther, Ole, Brunak, Søren, von Heijne, G. & Nielsen, H., 2022, In: Nature Biotechnology. 40, p. 1023-1025Research output: Contribution to journal › Comment/debate › Research
- Published
PAMP-triggered genetic reprogramming involves widespread alternative transcription initiation and an immediate transcription factor wave
Thieffry, A., López Márquez, Diego, Lange, Jette Bornholdt, Gholami Malekroudi, M., Bressendorff, Simon, Barghetti, A., Sandelin, Albin Gustav & Brodersen, Peter, 2022, In: The Plant Cell. 34, 7, 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DeepLoc 2.0: multi-label subcellular localization prediction using protein language models
Thumuluri, V., Almagro Armenteros, J. J., Johansen, A. R., Nielsen, H. & Winther, Ole, 2022, In: Nucleic Acids Research. 50, W1, p. W228-W234Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nuclear and cytoplasmic RNA exosomes and PELOTA1 prevent miRNA-induced secondary siRNA production in Arabidopsis
Vigh, Maria Louisa, Bressendorff, Simon, Thieffry, A., Arribas Hernandez, Laura & Brodersen, Peter, 2022, In: Nucleic Acids Research. 50, 3, p. 1396-1415 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms Underlying siRNA Amplification in Arabidopsis thaliana
Vigh, Maria Louisa, 2022, Department of Biology, Faculty of Science, University of Copenhagen. 201 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Genetics of early-life head circumference and genetic correlations with neurological, psychiatric and cognitive outcomes
Vogelezang, S., Bradfield, J. P., Early Growth Genetics Consortium, Ahluwalia, T. V. S., Liu, X., Schnurr, T. M., Frithioff-Bøjsøe, C., Bønnelykke, K., Lind, M. V., Lauritzen, L., Michaelsen, K. F., Lund, M. A. V., Melbye, M., Morgen, C. S., Pedersen, O. B., Holm, J-C., Grarup, N., Hansen, T., Nohr, E. A., Bisgaard, H. & 3 others, , 2022, In: BMC Medical Genomics. 15, 16 p., 124.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pseudoreplication in genomics-scale data sets
Waples, R. S., Waples, R. K. & Ward, E. J., 2022, In: Molecular Ecology Resources. 22, 2, p. 503-518 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physiological responses of narwhals to anthropogenic noise: A case study with seismic airguns and vessel traffic in the Arctic
Williams, T. M., Blackwell, S. B., Tervo, O., Garde, E., Sinding, Mikkel Holger Strander, Richter, B. & Heide-Jørgensen, M. P., 2022, In: Functional Ecology. 36, 9, p. 2251-2266 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Computational identification of signals predictive for nuclear RNA exosome degradation pathway targeting
Wu, M., Schmid, M., Jensen, T. H. & Sandelin, Albin Gustav, 2022, In: NAR Genomics and Bioinformatics. 4, 3, 18 p., lqac071.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two novel truncating variants of the ASPM gene identified in a nonconsanguineous Chinese family associated with primary microcephaly
Xu, S., Zhang, W., Zhou, R., Huang, H., Chen, W., Xiang, W., Liu, L. & Song, J., 2022, In: Clinical Dysmorphology. 31, 1, p. 1-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Contrastive learning enables rapid mapping to multimodal single-cell atlas of multimillion scale
YANG, Meng, Yang, Y., Xie, C., Ni, M., Liu, J., Yang, H., Mu, F. & Wang, J., 2022, In: Nature Machine Intelligence. 4, 8, p. 696-709 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrating convolution and self-attention improves language model of human genome for interpreting non-coding regions at base-resolution
YANG, Meng, Huang, L., Huang, H., Tang, H., Zhang, N., Yang, H., Wu, J. & Mu, F., 2022, In: Nucleic Acids Research. 50, 14, 19 p., e81.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TrustGWAS: A full-process workflow for encrypted GWAS using multi-key homomorphic encryption and pseudorandom number perturbation
YANG, Meng, Zhang, C., Wang, X., Liu, X., Li, S., Huang, J., Feng, Z., Sun, X., Chen, F., Yang, S., Ni, M., Li, L., Cao, Y. & Mu, F., 2022, In: Cell Systems. 13, 9, p. 752-767.e6 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single-cell transcriptomic landscape of the sheep rumen provides insights into physiological programming development and adaptation of digestive strategies
Yuan, Y., Sun, D., Qin, T., Mao, S., Zhu, W., Yin, Y., Huang, J., Heller, Rasmus, Li, Z., Liu, J. & Qiu, Q., 2022, In: Zoological research. 43, 4, p. 634-647 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical application of high-throughput sequencing technology in prenatal screening and diagnosis of birth defects
ZENG, F., 2022, Department of Biology, Faculty of Science, University of Copenhagen. 118 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Current challenges in understanding the role of enhancers in disease
Zaugg, J. B., Sahlén, P., Andersson, Robin, Alberich-Jorda, M., de Laat, W., Deplancke, B., Ferrer, J., Mandrup, S., Natoli, G., Plewczynski, D., Rada-Iglesias, A. & Spicuglia, S., 2022, In: Nature Structural and Molecular Biology. 29, 12, p. 1148-1158 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Performance characterization of PCR-free whole genome sequencing for clinical diagnosis
Zhou, G., Zhou, M., Zeng, F., Zhang, N., Sun, Y., Qiao, Z., Guo, X., Zhou, S., Yun, G., Xie, J., Wang, X., Liu, F., Fan, C., Wang, Y., Fang, Z., Tian, Z., Dai, W., Sun, J., Peng, Z. & Song, L., 2022, In: Medicine. 101, 10, 8 p., e28972.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimation of the covariance structure from SNP allele frequencies
van Waaij, J., Li, Z. & Wiuf, Carsten, 2022, In: Statistical Applications in Genetics and Molecular Biology. 21, 1, 20 p., 20220005.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced chromatin accessibility correlates with resistance to Notch activation
van den Ameele, J., Krautz, Robert, Cheetham, S. W., Donovan, A. P. A., Llorà-Batlle, O., Yakob, R. & Brand, A. H., 2022, In: Nature Communications. 13, 1, 10 p., 2210.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evolutionary consequences of genomic deletions and insertions in the woolly mammoth genome
van der Valk, T., Dehasque, M., Chacón-Duque, J. C., Oskolkov, N., Vartanyan, S., Heintzman, P. D., Chrzanová Pecnerová, Patrícia, Díez-del-Molino, D. & Dalén, L., 2022, In: iScience. 25, 8, 11 p., 104826.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Circulating Free Fatty Acid and Phospholipid Signature Predicts Early Rapid Kidney Function Decline in Patients With Type 1 Diabetes
Afshinnia, F., Rajendiran, T. M., He, C., Byun, J., Montemayor, D., Darshi, M., Tumova, J., Kim, J., Limonte, C. P., Miller, R. G., Costacou, T., Orchard, T. J., Ahluwalia, Tarun Veer Singh, Rossing, Peter, Snell-Bergeon, J. K., de Boer, I. H., Natarajan, L., Michailidis, G., Sharma, K. & Pennathur, S., 2021, In: Diabetes Care. 44, 9, p. 2098-2106 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Principles of mRNA targeting via the Arabidopsis m6A-binding protein ECT2
Arribas Hernandez, Laura, Rennie, Sarah, Köster, T., Porcelli, C., Lewinski, M., Staiger, D., Andersson, Robin & Brodersen, Peter, 2021, In: eLife. 10, 33 p., e72375.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The YTHDF proteins ECT2 and ECT3 bind largely overlapping target sets and influence target mRNA abundance, not alternative polyadenylation
Arribas Hernandez, Laura, Rennie, Sarah, Schon, M., Porcelli, C., Enugutti, B., Andersson, Robin, Nodine, M. D. & Brodersen, Peter, 2021, In: eLife. 10, 27 p., e72377.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bending during seedling emergence: Mechanochemical insight
Bai, B., 2021, In: Trends in Plant Science. 26, 9, p. 879-881 3 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Cardiovascular autonomic neuropathy and the impact on progression of diabetic kidney disease in type 1 diabetes
Bjerre-Christensen, T., Winther, S. A., Tofte, N., Theilade, S., Ahluwalia, Tarun Veer Singh, Lajer, M., Hansen, T. W., Rossing, Peter & Hansen, C. S., 2021, In: B M J Open Diabetes Research & Care. 9, 1, 9 p., e002289.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The endangered White Sands pupfish (Cyprinodon tularosa) genome reveals low diversity and heterogenous patterns of differentiation
Black, A. N., Willoughby, J. R., Brüniche-Olsen, Anna, Pierce, B. L. & DeWoody, J. A., 2021, In: Molecular Ecology Resources. 21, 7, p. 2520-2532 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Life-history traits and habitat availability shape genomic diversity in birds: implications for conservation
Brüniche-Olsen, Anna, Kellner, K. F., Belant, J. L. & DeWoody, J. A., 2021, In: Proceedings of the Royal Society B: Biological Sciences. 288, 1961, 9 p., 21001441.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptome Analysis Identifies GATA3-AS1 as a Long Noncoding RNA Associated with Resistance to Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer Patients
Contreras-Espinosa, L., Alcaraz, N., De La Rosa-Velázquez, I. A., Díaz-Chávez, J., Cabrera-Galeana, P., Rebollar-Vega, R., Reynoso-Noverón, N., Maldonado-Martínez, H. A., González-Barrios, R., Montiel-Manríquez, R., Bautista-Sánchez, D., Castro-Hernández, C., Alvarez-Gomez, R. M., Jiménez-Trejo, F., Tapia-Rodríguez, M., García-Gordillo, J. A., Pérez-Rosas, A., Bargallo-Rocha, E., Arriaga-Canon, C. & Herrera, L. A., 2021, In: Journal of Molecular Diagnostics. 23, 10, p. 1306-1323 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Low-Expression Variant of FABP4 Is Associated With Cardiovascular Disease in Type 1 Diabetes
Dahlström, E. H., Saksi, J., Forsblom, C., Uglebjerg, N., Mars, N., Thorn, L. M., Harjutsalo, V., Rossing, Peter, Ahluwalia, Tarun Veer Singh, Lindsberg, P. J., Sandholm, N., Groop, P. H. & FinnDiane Study Group, F. S. G., 2021, In: Diabetes. 70, 10, p. 2391-2401 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combining Bayesian age models and genetics to investigate population dynamics and extinction of the last mammoths in northern Siberia
Dehasque, M., Chrzanová Pecnerová, Patrícia, Muller, H., Tikhonov, A., Nikolskiy, P., Tsigankova, V. I., Danilov, G. K., Díez-del-Molino, D., Vartanyan, S., Dalén, L. & Lister, A. M., 2021, In: Quaternary Science Reviews. 259, 10 p., 106913.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
AutoCNV: a semiautomatic CNV interpretation system based on the 2019 ACMG/ClinGen Technical Standards for CNVs
Fan, C., Wang, Z., Sun, Y., Sun, J., Liu, X., Kang, L., Xu, Y., Yang, M., Dai, W., Song, L., Wei, X., Xiang, J., Huang, H., Zhou, M., Zeng, F., Huang, L., Xu, Z. & Peng, Z., 2021, In: BMC Genomics. 22, 12 p., 721.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reducing the rate of psychiatric re-admissions in bipolar disorder using smartphones - The RADMIS trial
Faurholt-Jepsen, M., Lindbjerg Tønning, M., Fros, M., Martiny, Klaus, Tuxen, N., Rosenberg, N., Busk, J., Winther, Ole, Thaysen-Petersen, D., Aamund, K. A., Tolderlund, L., Bardram, J. E. & Kessing, Lars Vedel, 2021, In: Acta Psychiatrica Scandinavica. 143, 5, p. 453-465 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptional Profiles Reveal Deregulation of Lipid Metabolism and Inflammatory Pathways in Neurons Exposed to Palmitic Acid
Flores-León, M., Alcaraz, N., Pérez-Domínguez, M., Torres-Arciga, K., Rebollar-Vega, R., De la Rosa-Velázquez, I. A., Arriaga-Canon, C., Herrera, L. A., Arias, C. & González-Barrios, R., 2021, In: Molecular Neurobiology. 58, 9, p. 4639-4651 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The genetic impact of an Ebola outbreak on a wild gorilla population
Fontsere, C., Frandsen, P., Hernandez-Rodriguez, J., Niemann, Jonas, Scharff-Olsen, Camilla Hjorth, Vallet, D., Le Gouar, P., Ménard, N., Navarro, A., Siegismund, Hans Redlef, Hvilsom, C., Gilbert, M Thomas P, Kuhlwilm, M., Hughes, D. & Marques-Bonet, T., 2021, In: BMC Genomics. 22, 12 p., 735.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A comparison of tools for copy-number variation detection in germline whole exome and whole genome sequencing data
Gabrielaite, M., Torp, M., Rasmussen, M., Andreu-Sánchez, S., Vieira, Filipe Garrett, Pedersen, C., Kinalis, S., Madsen, M., Yde, C., Rønn, O. L., Marvig, R., Østrup, O., Rossing, Caroline Maria, Nielsen, Finn Cilius, Winther, Ole & Bagger, F. O., 2021, bioRxiv, 29 p.Research output: Working paper › Preprint › Research
- Published
A comparison of tools for copy-number variation detection in germline whole exome and whole genome sequencing data
Gabrielaite, M., Torp, M. H., Rasmussen, Malthe Sebro, Andreu-Sánchez, S., Vieira, Filipe Garrett, Pedersen, C. B., Kinalis, S., Madsen, M. B., Kodama, M., Demircan, G. S., Simonyan, A., Yde, C. W., Olsen, L. R., Marvig, R. L., Østrup, O., Rossing, Caroline Maria, Nielsen, Finn Cilius, Winther, Ole & Bagger, F. O., 2021, In: Cancers. 13, 24, 6283.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vicariance followed by secondary gene flow in a young gazelle species complex
Garcia Erill, Genís, Kjær, M. M., Albrechtsen, Anders, Siegismund, Hans Redlef & Heller, Rasmus, 2021, In: Molecular Ecology. 30, 2, p. 528-544Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Computational methods for chromosome-scale haplotype reconstruction
Garg, S., 2021, In: Genome Biology. 22, 24 p., 101.Research output: Contribution to journal › Review › Research › peer-review
- Published
Light-Dependent Translation Change of Arabidopsis psbA Correlates with RNA Structure Alterations at the Translation Initiation Region
Gawroński, P., Enroth, Christel Hougård, Kindgren, P., Marquardt, Sebastian, Karpiński, S., Leister, D., Jensen, Poul Erik, Vinther, Jeppe & Scharff, L. B., 2021, In: Cells. 10, 2, 22 p., 322.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bsgatlas: A unified bacillus subtilis genome and transcriptome annotation atlas with enhanced information access
Geissler, Adrian Sven, Anthon, Christian, Alkan, F., González-Tortuero, E., Poulsen, L. D., Kallehauge, T. B., Breüner, A., Seemann, Ernst Stefan, Vinther, Jeppe & Gorodkin, Jan, 2021, In: Microbial Genomics. 7, 2, 17 p., 000524.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mapping the degradation pathway of a disease-linked aspartoacylase variant
Gersing, S. K., Wang, Y., Grønbæk-Thygesen, Martin, Kampmeyer, Caroline, Bjørnkjær, Lene, Willemoës, Martin, Andréasson, C., Stein, Amelie, Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2021, In: PLOS Genetics. 17, 4, 28 p., e1009539.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
De novo whole-genome assembly and resequencing resources for the roan (Hippotragus equinus), an iconic African antelope
Gonçalves, M., Siegismund, Hans Redlef, Van Vuuren, B. J., Koepfli, K., Ferrand, N. & Godinho, R., 2021, In: G3: Genes, Genomes, Genetics. 11, 2, 9 p., jkab002.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evolutionary history of the roan antelope across its African range
Gonçalves, M., Siegismund, Hans Redlef, van Vuuren, B. J., Ferrand, N. & Godinho, R., 2021, In: Journal of Biogeography. 48, 11, p. 2812-2827 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network
Grapotte, M., Saraswat, M., Bessière, C., Menichelli, C., Ramilowski, J. A., Severin, J., Hayashizaki, Y., Itoh, M., Tagami, M., Murata, M., Kojima-Ishiyama, M., Noma, S., Noguchi, S., Kasukawa, T., Hasegawa, A., Suzuki, H., Nishiyori-Sueki, H., Frith, M. C., Abugessaisa, I., Aitken, S. & 31 others, , 2021, In: Nature Communications. 12, 18 p., 3297.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A reference-free approach to analyse RADseq data using standard next generation sequencing toolkits
Heller, Rasmus, Nursyifa, Casia, Garcia Erill, Genís, Salmona, J., Chikhi, L., Meisner, Jonas, Korneliussen, Thorfinn Sand & Albrechtsen, Anders, 2021, In: Molecular Ecology Resources. 21, 4, p. 1085-1097 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma IL-8 and ICOSLG as prognostic biomarkers in glioblastoma
Holst, Camilla Bjørnbak, Christensen, I. J., Vitting-Seerup, K., Skjøth-Rasmussen, J., Hamerlik, P., Poulsen, H. S. & Johansen, Julia Sidenius, 1 Jan 2021, In: Neuro-Oncology Advances. 3, 1Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TrancriptomeReconstructoR: data-driven annotation of complex transcriptomes
Ivanov, M., Sandelin, Albin Gustav & Marquardt, Sebastian, 2021, In: BMC Bioinformatics. 22, 15 p., 290.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., Adamopoulos, I. E., Adeli, K., Adolph, T. E., Adornetto, A., Aflaki, E., Agam, G., Agarwal, A., Aggarwal, B. B., Agnello, M., Agostinis, P. & 2,908 others, , 2021, In: Autophagy. 17, p. 1-382 382 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Benchmarking blockchain-based gene-drug interaction data sharing methods: A case study from the iDASH 2019 secure genome analysis competition blockchain track
Kuo, T., Bath, T., Ma, S., Pattengale, N., YANG, Meng, Cao, Y., Hudson, C. M., Kim, J., Post, K., Xiong, L. & Ohno-Machado, L., 2021, In: International Journal of Medical Informatics. 154, 8 p., 104559.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The LEAFY floral regulator displays pioneer transcription factor properties
Lai, X., Blanc-Mathieu, R., GrandVuillemin, L., Huang, Y., Stigliani, Arnaud, Lucas, J., Thévenon, E., Loue-Manifel, J., Turchi, L., Daher, H., Brun-Hernandez, E., Vachon, G., Latrasse, D., Benhamed, M., Dumas, R., Zubieta, C. & Parcy, F., 2021, In: Molecular Plant. 14, 5, p. 829-837 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CDX2 regulates interleukin-33 gene expression in intestinal epithelial cells (LS174T)
Larsen, S., Seidelin, Jakob Benedict, Davidsen, J., Dahlgaard, K., Nielsen, Claus Henrik, Bennett, Eric Paul, Pedersen, O. B., Coskun, M. & Troelsen, J. T., 2021, In: FEBS Open Bio. 11, 6, p. 1638-1644Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Opportunities and challenges of macrogenetic studies
Leigh, D. M., van Rees, C. B., Millette, K. L., Breed, M. F., Schmidt, C., Bertola, Laura, Hand, B. K., Hunter, M. E., Jensen, E. L., Kershaw, F., Liggins, L., Luikart, G., Manel, S., Mergeay, J., Miller, J. M., Segelbacher, G., Hoban, S. & Paz-Vinas, I., 2021, In: Nature Reviews Genetics. 22, 12, p. 791-807 17 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Giraffa camelopardalis
Liu, C., Gao, J., Huang, J., Wang, W., Heller, Rasmus & Qiu, Q., 2021, In: Trends in Genetics. 37, 9, p. 860-861 2 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
A towering genome: Experimentally validated adaptations to high blood pressure and extreme stature in the giraffe
Liu, C., Gao, J., Cui, X., Li, Z., Chen, L., Yuan, Y., Zhang, Y., Mei, L., Zhao, L., Cai, D., Hu, M., Zhou, B., Li, Z., Qin, T., Si, H., Li, G., Lin, Z., Xu, Y., Zhu, C., Yin, Y. & 9 others, , 2021, In: Science Advances. 7, 12, 13 p., eabe9459.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Three de novo variants in KMT2A (MLL) identified by whole exome sequencing in patients with Wiedemann–Steiner syndrome
Luo, S., Bi, B., Zhang, W., Zhou, R., Chen, W., Zhao, P., Huang, Y., Yuan, L. & He, X., 2021, In: Molecular Genetics & Genomic Medicine. 9, 10, 11 p., e1798.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unveiling mRNP composition by fluorescence correlation and cross-correlation spectroscopy using cell lysates
Mateu-Regué, À., Christiansen, Jan, Bagger, F. O., Hellriegel, C. & Nielsen, Finn Cilius, 2021, In: Nucleic Acids Research. 49, 20, 15 p., e119.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The AIMe registry for artificial intelligence in biomedical research
Matschinske, J., Alcaraz, N., Benis, A., Golebiewski, M., Grimm, D. G., Heumos, L., Kacprowski, T., Lazareva, O., List, M., Louadi, Z., Pauling, J. K., Pfeifer, N., Röttger, R., Schwämmle, V., Sturm, G., Traverso, A., Van Steen, K., de Freitas, M. V., Villalba Silva, G. C., Wee, L. & 5 others, , 2021, In: Nature Methods. 18, 10, p. 1128-1131 4 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Detecting selection in low-coverage high-throughput sequencing data using principal component analysis
Meisner, Jonas, Albrechtsen, Anders & Hanghøj, Kristian Ebbesen, 2021, In: BMC Bioinformatics. 22, 13 p., 470.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large-scale inference of population structure in presence of missingness using PCA
Meisner, Jonas, Liu, S., Huang, M. & Albrechtsen, Anders, 2021, In: Bioinformatics. 37, 13, p. 1868-1875 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identifying a living great-grandson of the Lakota Sioux leader Tatanka Iyotake (Sitting Bull)
Moltke, Ida, Korneliussen, Thorfinn Sand, Seguin-Orlando, A., Moreno Mayar, J. Víctor, LaPointe, E., Billeck, W. & Willerslev, Eske, 2021, In: Science Advances. 7, 44, 7 p., eabh2013.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NetTCR-2.0 enables accurate prediction of TCR-peptide binding by using paired TCRα and β sequence data
Montemurro, A., Schuster, Viktoria, Povlsen, H. R., Bentzen, A. K., Jurtz, V., Chronister, W. D., Crinklaw, A., Hadrup, S. R., Winther, Ole, Peters, B., Jessen, L. E. & Nielsen, M., 2021, In: Communications Biology . 4, 13 p., 1060.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of a traditional and western diet on glucose homeostasis in Greenlandic Inuit carriers and non-carriers of type 2 diabetes variant in the TBC1D4 gene: A protocol for a randomized clinical trial
Møller, G., Lind, M. V., Hauptmann, A. L., Senftleber, N., Hansen, C. B., Hansen, Torben, Jørgensen, M. E. & Lauritzen, Lotte, 2021, In: Contemporary Clinical Trials Communications. 21, 6 p., 100734.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multiplexed assays reveal effects of missense variants in MSH2 and cancer predisposition
Nielsen, S. V., Hartmann-Petersen, Rasmus, Stein, Amelie & Lindorff-Larsen, Kresten, 2021, In: PLOS Genetics. 17, 4, 6 p., e1009496.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mapping the human genetic architecture of COVID-19
Niemi, M. E. K., Karjalainen, J., Liao, R. G., Neale, B. M., Daly, M., Ganna, A., Pathak, G. A., Andrews, S. J., Kanai, M., Veerapen, K., Fernandez-Cadenas, I., Schulte, E. C., Striano, P., Marttila, M., Minica, C., Marouli, E., Karim, M. A., Wendt, F. R., Savage, J., Sloofman, L. & 41 others, , 2021, In: Nature. 600, p. 472-477Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improved metagenome binning and assembly using deep variational autoencoders
Nissen, J. N., Johansen, Joachim, Allesoe, R. L., Sonderby, C. K., Armenteros, J. J. A., Grønbech, Christopher Heje, Jensen, Lars Juhl, Nielsen, H. B., Petersen, T. N., Winther, Ole & Rasmussen, Simon, 2021, In: Nature Biotechnology. 39, p. 555-560Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A large-scale genome-wide gene expression analysis in peripheral blood identifies very few differentially expressed genes related to antidepressant treatment and response in patients with major depressive disorder
Nøhr, A. K., Lindow, M., Forsingdal, A., Demharter, S., Nielsen, T., Buller, R., Moltke, Ida, Vitezic, M. & Albrechtsen, Anders, 2021, In: Neuropsychopharmacology. 46, 7, p. 1324-1332 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NGSremix: A software tool for estimating pairwise relatedness between admixed individuals from next-generation sequencing data
Nøhr, A. K., Hanghøj, Kristian Ebbesen, Garcia Erill, Genís, Li, Zilong, Moltke, Ida & Albrechtsen, Anders, 2021, In: G3: Genes, Genomes, Genetics. 11, 8, 8 p., jkab174.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Predictors and trajectories of treatment response to SSRIs in patients suffering from PTSD
Nøhr, A. K., Eriksson, H., Hobart, M., Moltke, Ida, Buller, R., Albrechtsen, Anders & Lindgreen, S., 2021, In: Psychiatry Research. 301, 8 p., 113964.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
netDx: Software for building interpretable patient classifiers by multi-'omic data integration using patient similarity networks [version 2; peer review: 2 approved]
Pai, S., Weber, P., Isserlin, R., Kaka, H., Hui, S., Shah, M. A., Giudice, L., Giugno, R., Nøhr, A. K., Baumbach, J. & Bader, G. D., 2021, In: F1000Research. 9, 42 p., 1239.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modes of genetic adaptations underlying functional innovations in the rumen
Pan, X., Cai, Y., Li, Z., Chen, X., Heller, R., Wang, N., Wang, Y., Zhao, C., Wang, Y., Xu, H., Li, S., Li, M., Li, C., Hu, S., Li, H., Wang, K., Chen, L., Wei, B., Zheng, Z., Fu, W. & 20 others, , 2021, In: Science China Life Sciences. 64, 1, p. 1-21 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mammuthus sp. (Early and Middle Pleistocene Mammoths)
Chrzanová Pecnerová, Patrícia, Díez-del-Molino, D., van der Valk, T., Dehasque, M., Götherström, A. & Dalén, L., 2021, In: Trends in Genetics. 37, 7, p. 682-683 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Genome-wide and sister chromatid-resolved profiling of protein occupancy in replicated chromatin with ChOR-seq and SCAR-seq
Petryk, N., Reveron-Gomez, Nazaret, González-Aguilera, C., Dalby, M., Andersson, Robin & Groth, Anja, 2021, In: Nature Protocols. 16, p. 4446-4493Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High genetic diversity and low differentiation reflect the ecological versatility of the African leopard
Chrzanová Pecnerová, Patrícia, Garcia Erill, Genís, Liu, Xiaodong, Nursyifa, Casia, Waples, R. K., Santander, Cindy, Quinn, Liam James Elgaard, Frandsen, P., Meisner, Jonas, Stæger, Frederik Filip Vinggaard, Rasmussen, Malthe Sebro, Brüniche-Olsen, Anna, Jørgensen, C. H. F., Rodrigues da Fonseca, Rute Andreia, Siegismund, Hans Redlef, Albrechtsen, Anders, Heller, Rasmus, Moltke, Ida & Hanghøj, Kristian Ebbesen, 2021, In: Current Biology. 31, 9, p. 1862-1871, e1-e5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
How robust are cross-population signatures of polygenic adaptation in humans?
Refoyo Martínez, Alba, Liu, S., Jørgensen, A. M., Jin, X., Albrechtsen, Anders, Martin, A. R. & Racimo, Fernando, 2021, In: Peer Community Journal. 1, 54 p., e22.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
hyperTRIBER: a flexible R package for the analysis of differential RNA editing
Rennie, Sarah, Magnusson, D. H. & Andersson, Robin, 2021, 12 p.Research output: Working paper › Preprint › Research
- Published
Time-efficient Bayesian Inference for a (Skewed) von Mises Distribution on the Torus in a Deep Probabilistic Programming Language
Rønning, Ola, Ley, C., Mardia, K. V. & Hamelryck, Thomas Wim, 2021, 2021 IEEE International Conference on Multisensor Fusion and Integration for Intelligent Systems (MFI). IEEE, p. 1-8Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
- Published
Pleistocene origins, western ghost lineages, and the emerging phylogeographic history of the red wolf and coyote
Sacks, B. N., Mitchell, K. J., Quinn, C. B., Hennelly, L. M., Sinding, Mikkel Holger Strander, Statham, M. J., Preckler-Quisquater, S., Fain, S. R., Kistler, L., Vanderzwan, S. L., Meachen, J. A., Ostrander, E. A. & Frantz, L. A. F., 2021, In: Molecular Ecology. 30, 17, p. 4292-4304 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative transcriptome analysis reveals key epigenetic targets in SARS-CoV-2 infection
Salgado-Albarrán, M., Navarro-Delgado, E. I., Del Moral-Morales, A., Alcaraz, N., Baumbach, J., González-Barrios, R. & Soto-Reyes, E., 2021, In: n p j Systems Biology and Applications. 7, 14 p., 21.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physical activity attenuates postprandial hyperglycaemia in homozygous TBC1D4 loss-of-function mutation carriers
Schnurr, T. M., Jørsboe, E., Chadt, A., Dahl-Petersen, I. K., Kristensen, Jonas Møller, Wojtaszewski, Jørgen F P, Springer, C., Bjerregaard, P., Brage, S., Pedersen, Oluf Borbye, Moltke, Ida, Grarup, Niels, Al-Hasani, H., Albrechtsen, Anders, Jørgensen, M. E. & Hansen, Torben, 2021, In: Diabetologia. 64, p. 1795-1804Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative single-cell proteomics as a tool to characterize cellular hierarchies
Schoof, E. M., Furtwängler, Benjamin, Üresin, Nil, Rapin, N., Savickas, S., Gentil, C., Lechman, E., Keller, U. A. D., Dick, J. E. & Porse, Bo Torben, 7 Jun 2021, In: Nature Communications. 12, 1, p. 3341Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disorder in a two-domain neuronal Ca2+-binding protein regulates domain stability and dynamics using ligand mimicry
Staby, L., Kemplen, K. R., Stein, Amelie, Ploug, Michael, Clarke, J., Skriver, Karen, Heidarsson, P. O. & Kragelund, Birthe Brandt, 2021, In: Cellular and molecular life sciences : CMLS. 78, p. 2263-2278 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Emergence and radiation of distemper viruses in terrestrial and marine mammals
Stokholm, Iben, Puryear, W., Sawatzki, K., Knudsen, Steen Wilhelm, Terkelsen, Thilde Bagger, Becher, P., Siebert, U. & Olsen, Morten Tange, 2021, In: Proceedings of the Royal Society B: Biological Sciences. 288, 1961, 9 p., 20211969.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic Stability and Phenotypic Characteristics of Industrially Produced Lacticaseibacillus rhamnosus GG in a Yogurt Matrix
Strickertsson, Marianne Stage, Hui, Y., Nielsen, Dennis Sandris, Vera-Jimenéz, N. I., Olsen, J., Sandelin, Albin Gustav & Wichmann, A., 2021, In: Applied and Environmental Microbiology. 87, 24, 18 p., e01575-21.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-throughput proteomics of breast cancer interstitial fluid: identification of tumor subtype-specific serologically relevant biomarkers
Terkelsen, T., Pernemalm, M., Gromov, P., Borresen-Dale, A., Krogh, Anders, Haakensen, V. D., Lethio, J., Papaleo, E. & Gromova, I., 2021, In: Molecular Oncology. 15, 2, p. 429-461 33 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficient Generative Modelling of Protein Structure Fragments using a Deep Markov Model
Thygesen, Christian Bahne, Al-Sibahi, A. S., Steenmanns, C. S., Sanz Moreta, Lys, Sørensen, A. B. & Hamelryck, Thomas Wim, 2021, International Conference on Machine Learning, 18-24 July 2021, Virtual. PMLR, p. 10258-10267 (Proceedings of Machine Learning Research, Vol. 139).Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
- Published
The effect of smartphone-based monitoring and treatment on the rate and duration of psychiatric readmission in patients with unipolar depressive disorder: The RADMIS randomized controlled trial
Tønning, M. L., Faurholt-Jepsen, Maria , Frost, M., Martiny, Klaus, Tuxen, N., Rosenberg, N., Busk, J., Winther, Ole, Melbye, S. A., Thaysen-Petersen, D., Aamund, K. A., Tolderlundh, L., Bardram, J. E. & Kessing, Lars Vedel, 2021, In: Journal of Affective Disorders. 282, p. 354-363 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The genetic history of Greenlandic-European contact
Waples, R. K., Hauptmann, A. L., Seiding, I. H., Jørsboe, E., Jørgensen, M. E., Grarup, Niels, Andersen, M. K., Larsen, C. V. L., Bjerregaard, P., Hellenthal, G., Hansen, Torben, Albrechtsen, Anders & Moltke, Ida, 2021, In: Current Biology. 31, 10, p. 2214-2219.e4Research output: Contribution to journal › Journal article › Research › peer-review
- Published
VeTra: a tool for trajectory inference based on RNA velocity
Weng, Guangzheng, Kim, Junil & Won, K. J., 2021, In: Bioinformatics. 37, 20, p. 3509-3513 btab364.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Technical Considerations for Transcatheter Aortic Valve Replacement With the Navitor Transcatheter Heart Valve
Wong, I., Bajoras, V., Wang, X., Bieliauskas, G., De Backer, Ole & Søndergaard, Lars, 2021, In: JACC: Cardiovascular Interventions. 14, 19, p. e259-e261Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigation of the Impact of the RNA Exosome on Cellular Transcriptome and Function
Wu, M., 2021, Department of Biology, Faculty of Science, University of Copenhagen. 154 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Enhancing CRISPR-Cas9 gRNA efficiency prediction by data integration and deep learning
Xiang, X., Corsi, G. I., Anthon, C., Qu, K., Pan, X., Liang, X., Han, P., Dong, Z., Liu, L., Zhong, J., Ma, T., Wang, J., Zhang, X., Jiang, H., Xu, F., Liu, X., Xu, X., Wang, J., Yang, H., Bolund, L. & 4 others, , 2021, In: Nature Communications. 12, 1, 9 p., 3238.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An integrated gene catalog and over 10,000 metagenome-assembled genomes from the gastrointestinal microbiome of ruminants
Xie, F., Jin, W., Si, H., Yuan, Y., Tao, Y., Liu, J., Wang, X., Yang, C., Li, Q., Yan, X., Lin, L., Jiang, Q., Zhang, L., Guo, C., Greening, C., Heller, R., Guan, L. L., Pope, P. B., Tan, Z., Zhu, W. & 4 others, , 2021, In: Microbiome. 9, 20 p., 137.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole Genome Sequencing in the Evaluation of Fetal Structural Anomalies: A Parallel Test with Chromosomal Microarray Plus Whole Exome Sequencing
Zhou, J., Yang, Z., Sun, J., Liu, L., Zhou, X., Liu, F., Xing, Y., Cui, S., Xiong, S., Liu, X., Yang, Y., Wei, X., Zou, G., Wang, Z., Wei, X., Wang, Y., Zhang, Y., Yan, S., Wu, F., Zeng, F. & 4 others, , 2021, In: Genes. 12, 3, 14 p., 376.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Million-year-old DNA sheds light on the genomic history of mammoths
van der Valk, T., Pečnerová, P., Díez-del-Molino, D., Bergström, A., Oppenheimer, J., Hartmann, S., Xenikoudakis, G., Thomas, J. A., Dehasque, M., Sağlıcan, E., Fidan, F. R., Barnes, I., Liu, S., Somel, M., Heintzman, P. D., Nikolskiy, P., Shapiro, B., Skoglund, P., Hofreiter, M., Lister, A. M. & 2 others, , 2021, In: Nature. 591, 7849, p. 265-269Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic insights into the conservation status of the world's last remaining Sumatran rhinoceros populations
von Seth, J., Dussex, N., Diez-del-Molino, D., van der Valk, T., Kutschera, V. E., Kierczak, M., Steiner, C. C., Liu, S., Gilbert, M. T. P., Sinding, M-H. S., Prost, S., Guschanski, K., Nathan, S. K. S. S., Brace, S., Chan, Y. L., Wheat, C. W., Skoglund, P., Ryder, O. A., Goossens, B., Gotherstrom, A. & 1 others, , 2021, In: Nature Communications. 12, 1, 11 p., 2393.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Co-Chaperones in Targeting and Delivery of Misfolded Proteins to the 26S Proteasome
Abildgaard, A. B., Gersing, S. K., Larsen-Ledet, Sven, Nielsen, S. V., Stein, Amelie, Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2020, In: Biomolecules. 10, 8, 24 p., 1141.Research output: Contribution to journal › Review › Research › peer-review
- Published
Genome wide association study of circulating interleukin 6 levels identifies novel loci
Ahluwalia, T. S., Armstrong, N. J., Aslibekyan, S., Beekman, M., Cheng, Y., deGeus, E., Delgado, G. E., Marek, D., Kanoni, S., Nolte, I. M., Porcu, E., Seppala, I., Standl, M., Teumer, A., Thalamuthu, A., Trompet, S., Benjamin, E. J., Feitosa, M. F., Homuth, G., Lahti, J. & 30 others, , 2020, In: European Journal of Human Genetics. 28, Supplement 1, p. 307-308 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
FUT2–ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses
Ahluwalia, T. S., Eliasen, A. U., Sevelsted, A., Pedersen, C-E. T., Stokholm, J., Chawes, B., Bork-Jensen, J., Grarup, N., Pedersen, O., Hansen, T., Linneberg, A., Sharma, A., Weiss, S. T., Evans, M. D., Jackson, D. J., Morin, A., Krogfelt, K. A., Schjørring, S., Mortensen, P. B., Hougaard, D. M. & 13 others, , 2020, In: Nature Communications. 11, 12 p., 6398.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative transcriptomics of primary cells in vertebrates
Alam, T., Agrawal, S., Severin, J., Young, R. S., Andersson, R., Arner, E., Hasegawa, A., Lizio, M., Ramilowski, J. A., Abugessaisa, I., Ishizu, Y., Noma, S., Tarui, H., Taylor, M. S., Lassmann, T., Itoh, M., Kasukawa, T., Kawaji, H., Marchionni, L., Sheng, G. & 5 others, , 2020, In: Genome Research. 30, 7, p. 951-961 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
De Novo Pathway Enrichment with KeyPathwayMiner
Alcaraz, N., Hartebrodt, A. & List, M., 2020, Protein-Protein Interaction Networks: Methods and Protocols. Canzar, S. & Ringeling, F. R. (eds.). Humana Press, p. 181-199 19 p. (Methods in Molecular Biology, Vol. 2074).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Reconstructing genome evolution in historic samples of the Irish potato famine pathogen
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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True single-molecule DNA sequencing of a pleistocene horse bone
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