Computational and RNA Biology

  1. Published

    Genomic insights into the origin and diversification of late maritime hunter-gatherers from the Chilean Patagonia

    De la Fuente, C., Avila-Arcos, M. C., Galimany, J., Carpenter, M. L., Homburger, J. R., Blanco, A., Contreras, P., Davalos, D. C., Reyes, O., Roman, M. S., Moreno-Estrada, A., Campos, P., Eng, C., Huntsman, S., Burchard, E. G., Malaspinas, A-S., Bustamante, C. D., Willerslev, E., Llop, E., Verdugo, R. A. & 1 others, Moraga, M., 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 17, p. E4006-E4012 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Co-Chaperones in Targeting and Delivery of Misfolded Proteins to the 26S Proteasome

    Abildgaard, A. B., Andersen, Sarah Gersing, Larsen-Ledet, Sven, Nielsen, S. V., Stein, Amelie, Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2020, In: Biomolecules. 10, 8, 24 p., 1141.

    Research output: Contribution to journalReviewResearchpeer-review

  3. Published

    Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome

    Abildgaard, A. B., Stein, Amelie, Nielsen, S. V., Schultz-Knudsen, Katrine, Papaleo, E., Shrikhande, A., Hoffmann, Eva, Bernstein, I., Gerdes, Anne-Marie Axø, Takahashi, M., Ishioka, C., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2019, In: eLife. 8, 28 p., e49138 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Age-associated DNA methylation changes in immune genes, histone modifiers and chromatin remodeling factors within 5 years after birth in human blood leukocytes

    Acevedo, N., Reinius, L. E., Vitezic, M., Fortino, V., Söderhäll, C., Honkanen, H., Veijola, R., Simell, O., Toppari, J., Ilonen, J., Knip, M., Scheynius, A., Hyöty, H., Greco, D. & Kere, J., 2015, In: Clinical Epigenetics. 7, 20 p., 34.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Fitness consequences of nest infiltration by the mutualist-exploiter Megalomyrmex adamsae

    Adams, R. M. M., Shah, K., Antonov, L. D. & Mueller, U. G., 2012, In: Ecological Entomology. 37, 6, p. 453-462 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    In vivo and in vitro studies of the neuronal RNA-binding protein Drosophila IMP

    Adolph, S. K., 2008, Biologisk Institut: Museum Tusculanum. 144 p.

    Research output: Book/ReportPh.D. thesisResearch

  7. Published

    Embryonic expression of Drosophila IMP in the developing CNS and PNS

    Adolph, S. K., Delotto, R., Nielsen, Finn Cilius & Christiansen, Jan, 2008, In: Gene Expression Patterns. 9, 3, p. 138-143 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2022 update

    Afgan, E., Nekrutenko, A., Grüning, B. A., Blankenberg, D., Goecks, J., Schatz, M. C., Ostrovsky, A. E., Mahmoud, A., Lonie, A. J., Syme, A., Fouilloux, A., Bretaudeau, A., Nekrutenko, A., Kumar, A., Eschenlauer, A. C., Desanto, A. D., Guerler, A., Serrano-Solano, B., Batut, B., Grüning, B. A. & 85 others, Langhorst, B. W., Carr, B., Raubenolt, B. A., Hyde, C. J., Bromhead, C. J., Barnett, C. B., Royaux, C., Gallardo, C., Blankenberg, D., Fornika, D. J., Baker, D., Bouvier, D., Clements, D., De Lima Morais, D. A., Tabernero, D. L., Lariviere, D., Nasr, E., Afgan, E., Zambelli, F., Heyl, F., Psomopoulos, F., Coppens, F., Price, G. R., Cuccuru, G., Corguillé, G. L., Von Kuster, G., Akbulut, G. G., Rasche, H., Hans-Rudolf, H., Eguinoa, I., Makunin, I., Ranawaka, I. J., Taylor, J. P., Joshi, J., Hillman-Jackson, J., Chilton, J. M., Kamali, K., Suderman, K., Poterlowicz, K., Yvan, L. B., Lopez-Delisle, L., Sargent, L., Bassetti, M. E., Tangaro, M. A., Van Den Beek, M., Cech, M., Bernt, M., Fahrner, M., Tekman, M., Föll, M. C., Schatz, M. C., Crusoe, M. R., Roncoroni, M., Kucher, N., Coraor, N., Stoler, N., Rhodes, N., Soranzo, N., Pinter, N., Goonasekera, N. A., Moreno, P. A., Videm, P., Melanie, P., Mandreoli, P., Jagtap, P. D., Gu, Q., Weber, R. J. M., Lazarus, R., Vorderman, R. H. P., Hiltemann, S., Golitsynskiy, S., Garg, S., Bray, S. A., Gladman, S. L., Leo, S., Mehta, S. P., Griffin, T. J., Jalili, V., Yves, V., Wen, V., Nagampalli, V. K., Bacon, W. A., De Koning, W., Maier, W. & Briggs, P. J., 2022, In: Nucleic Acids Research. 50, W1, p. W345-W351 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Circulating Free Fatty Acid and Phospholipid Signature Predicts Early Rapid Kidney Function Decline in Patients With Type 1 Diabetes

    Afshinnia, F., Rajendiran, T. M., He, C., Byun, J., Montemayor, D., Darshi, M., Tumova, J., Kim, J., Limonte, C. P., Miller, R. G., Costacou, T., Orchard, T. J., Ahluwalia, Tarun Veer Singh, Rossing, Peter, Snell-Bergeon, J. K., de Boer, I. H., Natarajan, L., Michailidis, G., Sharma, K. & Pennathur, S., 2021, In: Diabetes Care. 44, 9, p. 2098-2106 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells

    Agrawal-Singh, S., Lerdrup, Mads, Gomes, A. R., van de Werken, H. J. G., Johansen, Jens Vilstrup, Andersson, Robin, Sandelin, Albin Gustav, Helin, K. & Hansen, K., 2019, In: eLife. 8, p. 1-32 32 p., e40364.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Genome wide association study of circulating interleukin 6 levels identifies novel loci

    Ahluwalia, T. S., Armstrong, N. J., Aslibekyan, S., Beekman, M., Cheng, Y., deGeus, E., Delgado, G. E., Marek, D., Kanoni, S., Nolte, I. M., Porcu, E., Seppala, I., Standl, M., Teumer, A., Thalamuthu, A., Trompet, S., Benjamin, E. J., Feitosa, M. F., Homuth, G., Lahti, J. & 30 others, Liu, Y., Timpson, N. J., Visvikis-Siest, S., Voelker, U., Baune, B. T., Boomsma, D., Deary, I. J., Evans, D. M., Ferreira, M. A., Gaunt, T., Gudnason, V., Hamsten, A., Humphries, S. E., Koeing, W., Kumari, M., Lawlor, D. A., Nauck, M., Price, J. F., Sørensen, Thorkild I.A., Stacey, D., Stathopoulou, M. G., Tanaka, T., Wannamethee, S. G., Rotter, J. I., Dehghan, A., Boerwinkle, E., Sneider, H., Psaty, B. M., Prins, B. P. & Alizadeh, B. Z., 2020, In: European Journal of Human Genetics. 28, Supplement 1, p. 307-308 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  12. Published

    FUT2–ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses

    Ahluwalia, T. S., Eliasen, A. U., Sevelsted, A., Pedersen, C-E. T., Stokholm, J., Chawes, B., Bork-Jensen, J., Grarup, N., Pedersen, O., Hansen, T., Linneberg, A., Sharma, A., Weiss, S. T., Evans, M. D., Jackson, D. J., Morin, A., Krogfelt, K. A., Schjørring, S., Mortensen, P. B., Hougaard, D. M. & 13 others, Bybjerg-Grauholm, J., Bækvad-Hansen, M., Mors, O., Nordentoft, Merete, Børglum, A. D., Werge, Thomas, Agerbo, E., Gern, J. E., Lemanske, R. F., Ober, C., Pedersen, A. G., Bisgaard, H. & Bønnelykke, Klaus, 2020, In: Nature Communications. 11, 12 p., 6398.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Lack of the Major Multifunctional Catalase KatA in Pseudomonas aeruginosa Accelerates Evolution of Antibiotic Resistance in Ciprofloxacin-Treated Biofilms

    Ahmed, M. N., Porse, A., Abdelsamad, A., Sommer, M., Høiby, Niels & Ciofu, Oana, 2019, In: Antimicrobial Agents and Chemotherapy. 63, 10, 12 p., e00766-19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    A structural biology community assessment of AlphaFold2 applications

    Akdel, M., Pires, D. E., Porta Pardo, E., Jänes, J., Zalevsky, A. O., Meszaros, B., Bryant, P., Good, L. L., Laskowski, R. A., Pozzati, G., Shenoy, A., Zhu, W., Kundrotas, P., Serra, V. R., Rodrigues, C. H. M., Dunham, A. S., Burke, D., Borkakoti, N., Velankar, S., Frost, A. & 14 others, Basquin, J., Lindorff-Larsen, Kresten, Bateman, A., Kajava, A., Valencia, A., Ovchinnikov, S., Durairaj, J., Ascher, D. B., Thornton, J. M., Davey, N. E., Stein, Amelie, Elofsson, A., Croll, T. & Beltrao, P., 2022, In: Nature Structural & Molecular Biology. 29, 11, 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Probabilistic Programming for Voucher Information Extraction: Preliminary Practical Experiences

    Al-Sibahi, A. S., Hamelryck, Thomas Wim & Henglein, Fritz, 2018.

    Research output: Contribution to conferencePosterResearch

  16. Published

    Comparative transcriptomics of primary cells in vertebrates

    Alam, T., Agrawal, S., Severin, J., Young, R. S., Andersson, R., Arner, E., Hasegawa, A., Lizio, M., Ramilowski, J. A., Abugessaisa, I., Ishizu, Y., Noma, S., Tarui, H., Taylor, M. S., Lassmann, T., Itoh, M., Kasukawa, T., Kawaji, H., Marchionni, L., Sheng, G. & 5 others, Forrest, A. R. R., Khachigian, L. M., Hayashizaki, Y., Carninci, P. & de Hoon, M. J. L., 2020, In: Genome Research. 30, 7, p. 951-961 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Natural selection and the distribution of identity-by-descent in the human genome

    Albrechtsen, Anders, Moltke, Ida & Nielsen, Rasmus, 2010, In: Genetics. 186, 1, p. 295-308 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes

    Albrechtsen, A., Grarup, N., Li, Y., Sparsø, T. H., Tian, G., Cao, H., Jiang, T., Kim, S. Y., Korneliussen, T. S., Li, Q., Nie, C., Wu, R., Skotte, L., Morris, A. P., Ladenvall, C., Cauchi, S., Stancáková, A., Andersen, G., Astrup, A., Banasik, K. & 86 others, Bennett, A. J., Bolund, L., Charpentier, G., Chen, Y., Dekker, J. M., Doney, A. S. F., Dorkhan, M., Forsen, T., Frayling, T. M., Groves, C. J., Gui, Y., Hallmans, G., Hattersley, A. T., He, K., Hitman, G. A., Holmkvist, J., Huang, S., Jiang, H., Jin, X., Justesen, Johanne Marie, Kristiansen, Karsten, Kuusisto, J., Lajer, M., Lantieri, O., Li, W., Liang, H., Liao, Q., Liu, X., Ma, T., Ma, X., Manijak, M. P., Marre, M., Mokrosinski, J., Morris, A. D., Mu, B., Nielsen, A. A., Nijpels, G., Nilsson, P., Palmer, C. N. A., Rayner, N. W., Renström, F., Ribel-Madsen, R., Robertson, N., Rolandsson, O., Rossing, P., Schwartz, Thue W., Slagboom, P. E., Sterner, M., Tang, M., Tarnow, L., Tuomi, T., Van't Riet, E., van Leeuwen, N., V Varga, Tibor, Vestmar, M. A., Walker, M., Wang, B., Wang, Y., Wu, H., Xi, F., Yengo, L., Yu, C., Zhang, X., Zhang, J., Zhang, Q., Zhang, W., Zheng, H., Zhou, Y., Altshuler, D., 't Hart, L. M., Franks, P. W., Balkau, B., Froguel, P., McCarthy, M. I., Laakso, M., Groop, L., Christensen, C., Brandslund, I., Lauritzen, T., Witte, D. R., Linneberg, A., Jørgensen, T., Hansen, Torben, Wang, J., Nielsen, Rasmus & Pedersen, Oluf Borbye, 2013, In: Diabetologia. 56, 2, p. 298-310 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Relatedness mapping and tracts of relatedness for genome-wide data in the presence of linkage disequilibrium

    Albrechtsen, Anders, Korneliussen, Thorfinn Sand, Moltke, Ida, van Overseem Hansen, T., Nielsen, Finn Cilius & Nielsen, Rasmus, 2009, In: Genetic Epidemiology. 33, 3, p. 266-274

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Methods for fighting emerging pathogens

    Alcantara, L. C. J., Amenga-Etego, L., Andersson, Robin, Bhaumik, M., Choi, Y. K., Decaluwe, H., Geoghegan, J., Haagmans, B. L., López, S., Mukhtar, M. M., Nelwan, E., Rahal, E. A., Sato, K., Sklan, E. H. & Fang, Y. S. C., 2022, In: Nature Methods. 19, 4, p. 395-397 3 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  21. Published

    De novo pathway-based biomarker identification

    Alcaraz, N., List, M., Batra, R., Vandin, F., Ditzel, H. J. & Baumbach, J., 19 Sep 2017, In: Nucleic Acids Research. 45, 16, 11 p., e151.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    De Novo Pathway Enrichment with KeyPathwayMiner

    Alcaraz, N., Hartebrodt, A. & List, M., 2020, Protein-Protein Interaction Networks: Methods and Protocols. Canzar, S. & Ringeling, F. R. (eds.). Humana Press, p. 181-199 19 p. (Methods in Molecular Biology, Vol. 2074).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  23. Published

    Characterizing leader sequences of CRISPR loci

    Alkhnbashi, O., Shah, S. A., Garrett, Roger Antony, Saunders, S. J., Costa, F. & Backofen, R., 2016, In: Bioinformatics. 32, 17, p. i576-i585 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Extinct New Zealand megafauna were not in decline before human colonization

    Allentoft, Morten Erik, Heller, Rasmus, Oskam, C. L., Lorenzen, Eline, Hale, M. L., Gilbert, M Thomas P, Jacomb, C., Holdaway, R. N. & Bunce, M., 2014, In: Proceedings of the National Academy of Sciences USA (PNAS). 111, 13, p. 4922-4927 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Ancient DNA microsatellite analyses of the extinct New Zealand giant moa (Dinornis robustus) identify relatives within a single fossil site

    Allentoft, Morten Erik, Heller, Rasmus, Holdaway, R. N. & Bunce, M., 2015, In: Heredity. 115, p. 481-487 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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