Computational and RNA Biology

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  1. Published

    Cross-species ChIP-seq studies provide insights into regulatory strategies of PPAR¿ in adipocytes

    Schmidt, S. F., Jørgensen, M., Sandelin, Albin Gustav & Mandrup, S., 2012, In: Transcription. 3, 1, p. 19-24 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Crosstalk between tumor acidosis, p53 and extracellular matrix regulates pancreatic cancer aggressiveness

    Czaplinska, D., Ialchina, Renata, Andersen, Henriette Berg, Yao, Jiayi, Stigliani, Arnaud, Dannesboe, Johs, Flinck, M., Chen, X., Mitrega, J., Gnosa, S. P., Dmytriyeva, O., Alves, F., Napp, J., Sandelin, Albin Gustav & Pedersen, Stine Helene Falsig, 2023, In: International Journal of Cancer. 152, 6, p. 1210-1225 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Current and emerging approaches to define intestinal epithelium-specific transcriptional networks

    Olsen, A. K., Boyd, M., Danielsen, E. T. & Troelsen, J. T., Feb 2012, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 302, 3, p. G277-86

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Current challenges in understanding the role of enhancers in disease

    Zaugg, J. B., Sahlén, P., Andersson, Robin, Alberich-Jorda, M., de Laat, W., Deplancke, B., Ferrer, J., Mandrup, S., Natoli, G., Plewczynski, D., Rada-Iglesias, A. & Spicuglia, S., 2022, In: Nature Structural and Molecular Biology. 29, 12, p. 1148-1158 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Cytoplasmic mRNPs revisited: Singletons and condensates

    Mateu-Regue, A., Nielsen, Finn Cilius & Christiansen, Jan, 2020, In: BioEssays. 42, 12, 13 p., 2000097.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    DGCR8 HITS-CLIP reveals novel functions for the microprocessor

    Macias, S., Plass, M., Stajuda, A., Michlewski, G., Eyras, E. & Cáceres, J. F., 2012, In: Nature Structural and Molecular Biology. 19, 8

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    DGCR8 acts as an adaptor for the exosome complex to degrade double-stranded structured RNAs

    Macias, S., Cordiner, R. A., Gautier, P., Plass, M. & Caceres, J. F., 2015, In: Molecular Cell. 60, 6, p. 873-885 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    DNA metabarcoding illuminates the contribution of small and very small prey taxa to the diet of lions

    Groen, K., Beekenkamp, S., de Iongh, H. H., Lesilau, F., Chege, M., Narisha, L., Veldhuis, M., Bertola, Laura, van Bodegom, P. M. & Trimbos, K. B., 2023, In: Environmental DNA. 5, 6, p. 1321-1331 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    DNA supercoiling enhances cooperativity and efficiency of an epigenetic switch

    Norregaard, K., Andersson, M., Sneppen, Kim, Nielsen, Peter E., Brown, Stanley & Oddershede, L. B., 22 Oct 2013, In: Proceedings of the National Academy of Sciences USA (PNAS). 110, 43, p. 17386-91 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Daily estimates of clinical severity of symptoms in bipolar disorder from smartphone-based self-assessments

    Busk, J., Faurholt-Jepsen, M., Frost, M., Bardram, J. E., Kessing, Lars Vedel & Winther, Ole, 2020, In: Translational Psychiatry. 10, 12 p., 194.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    DamMet: ancient methylome mapping accounting for errors, true variants, and post-mortem DNA damage

    Hanghøj, Kristian Ebbesen, Renaud, Gabriel, Albrechtsen, Anders & Orlando, L., 2019, In: GigaScience. 8, 4, 6 p., giz025.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Darwinian and demographic forces affecting human protein coding genes.

    Nielsen, Rasmus, Hubisz, M. J., Hellmann, I., Torgerson, D., Andres, A. M., Albrechtsen, Anders, Gutenkunst, R., Adams, M. D., Cargill, M., Boyko, A., Indap, A., Bustamante, C. D. & Clark, A. G., 2009, In: Genome Research. 19, 5, p. 838-49 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    De Novo Assembly of 20 Chicken Genomes Reveals the Undetectable Phenomenon for Thousands of Core Genes on Microchromosomes and Subtelomeric Regions

    Li, M., Sun, C., Xu, N., Bian, P., Tian, X., Wang, X., Wang, Y., Jia, X., Heller, R., Wang, M., Wang, F., Dai, X., Luo, R., Guo, Y., Wang, X., Yang, P., Hu, D., Liu, Z., Fu, W., Zhang, S. & 10 others, Li, X., Wen, C., Lan, F., Siddiki, A. Z., Suwannapoom, C., Zhao, X., Nie, Q., Hu, X., Jiang, Y. & Yang, N., 2022, In: Molecular Biology and Evolution. 39, 4, 16 p., msac066.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    De Novo Pathway Enrichment with KeyPathwayMiner

    Alcaraz, N., Hartebrodt, A. & List, M., 2020, Protein-Protein Interaction Networks: Methods and Protocols. Canzar, S. & Ringeling, F. R. (eds.). Humana Press, p. 181-199 19 p. (Methods in Molecular Biology, Vol. 2074).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  15. Published

    De Novo Pathway-Based Classification of Breast Cancer Subtypes

    List, M., Alcaraz, N. & Batra, R., 2020, Protein-Protein Interaction Networks: Methods and Protocols. Canzar, S. & Ringeling, F. R. (eds.). Humana Press, p. 201-213 13 p. (Methods in Molecular Biology, Vol. 2074).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  16. Published

    Deciphering Transcriptional Regulation: Computational Approaches

    Valen, E., 2010, Museum Tusculanum. 97 p.

    Research output: Book/Report › Ph.D. thesis › Research

  17. Published

    Deciphering regulatory mechanisms underlying gene co-activity

    van Duin, Lucas, 2023, Department of Biology, Faculty of Science, University of Copenhagen. 131 p.

    Research output: Book/Report › Ph.D. thesis › Research

  18. Published

    Deconvolution of autoencoders to learn biological regulatory modules from single cell mRNA sequencing data

    Kinalis, S., Nielsen, Finn Cilius, Winther, Ole & Bagger, F. O., 2019, In: BMC Bioinformatics. 20, 9 p., 379.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Deep Learning for Diagnostic Binary Classification of Multiple-Lesion Skin Diseases

    Thomsen, K., Christensen, A. L., Iversen, L., Lomholt, H. B. & Winther, Ole, 2020, In: Frontiers in Medicine. 7, 7 p., 574329.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Deep Recurrent Conditional Random Field Network for Protein Secondary Prediction

    Johansen, A. R., Sønderby, C. K., Sønderby, S. K. & Winther, O., 2017, ACM-BCB '17: Proceedings of the 8th ACM International Conference on Bioinformatics, Computational Biology, and Health Informatics. p. 73-78 6 p.

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

  21. Published

    Deep integrative models for large-scale human genomics

    Sigurdsson, Arnór Ingi, Louloudis, Ioannis, Banasik, Karina, Westergaard, David, Winther, Ole, Lund, O., Ostrowski, Sisse Rye, Erikstrup, C., Pedersen, Ole Birger Vesterager, Nyegaard, Mette, Brunak, Søren, Vilhjálmsson, B. & Rasmussen, Simon, 2023, In: Nucleic Acids Symposium Series. 51, 12, 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Deep transcriptome profiling of mammalian stem cells supports a regulatory role for retrotransposons in pluripotency maintenance

    Fort, A., Hashimoto, K., Yamada, D., Salimullah, M., Keya, C. A., Saxena, A., Bonetti, A., Voineagu, I., Bertin, N., Kratz, A., Noro, Y., Wong, C-H., de Hoon, M., Andersson, R., Sandelin, A. G., Suzuki, H., Wei, C-L., Koseki, H., Hasegawa, Y., Forrest, A. R. R. & 2 others, Carninci, P. & FANTOM Consortium, F. C., 2014, In: Nature Genetics. 46, 6, p. 558-566 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Deep-sequencing of viral genomes from a large and diverse cohort of treatment-naive HIV-infected persons shows associations between intrahost genetic diversity and viral load

    INSIGHT START Study Group, I. S. S. G., 2023, In: PLOS Computational Biology. 19, 1, 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    DeepLoc: prediction of protein subcellular localization using deep learning

    Almagro Armenteros, J. J., Sønderby, C. K., Sønderby, S. K., Nielsen, H. & Winther, Ole, 1 Nov 2017, In: Bioinformatics. 33, 21, p. 3387-3395 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    DeepLoc 2.0: multi-label subcellular localization prediction using protein language models

    Thumuluri, V., Almagro Armenteros, J. J., Johansen, A. R., Nielsen, H. & Winther, Ole, 2022, In: Nucleic Acids Research. 50, W1, p. W228-W234

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    DeepLocRNA: an interpretable deep learning model for predicting RNA subcellular localization with domain-specific transfer-learning

    Wang, Jun, Horlacher, M., Cheng, L. & Winther, Ole, 2024, In: Bioinformatics. 40, 2, 10 p., btae065.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    DeepPeptide predicts cleaved peptides in proteins using conditional random fields

    Teufel, Felix Georg, Refsgaard, J. C., Madsen, C. T., Stahlhut, C., Grønborg, M., Winther, Ole & Madsen, D., 2023, In: Bioinformatics (Oxford, England). 39, 10, 6 p., btad616.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Demographic inferences from large-scale NGS data

    Pedersen, C. T., 2017, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  29. Published

    Deorphanizing Peptides Using Structure Prediction

    Teufel, Felix Georg, Refsgaard, J. C., Kasimova, M. A., Deibler, K., Madsen, C. T., Stahlhut, C., Grønborg, M., Winther, Ole & Madsen, D., 2023, In: Journal of Chemical Information and Modeling. 63, 9, 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    DermX: An end-to-end framework for explainable automated dermatological diagnosis

    Jalaboi, R., Faye, F., Orbes-Arteaga, M., Jørgensen, D., Winther, Ole & Galimzianova, A., 2023, In: Medical Image Analysis. 83, 12 p., 102647.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Design of association studies with pooled or un-pooled next-generation sequencing data

    Kim, S. Y., Li, Y., Guo, Y., Li, R., Holmkvist, J., Hansen, Torben, Pedersen, Oluf Borbye, Wang, J. & Nielsen, Rasmus, 2010, In: Genetic Epidemiology. 34, 5, p. 479-491 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Detecting host responses to microbial stimulation using primary epithelial organoids

    Lange, Jette Bornholdt, Müller, C. V., Nielsen, M. J., Strickertsson, J., Rago, D., Chen, Y., Maciag, Grzegorz Jerzy, Skov, Jonathan, Wellejus, A., Schweiger, P. J., Hansen, Stine Lind, Broholm, C., Gögenur, Ismail, Maimets, Martti, Sloth, S., Hendel, J., Baker, A., Sandelin, Albin Gustav & Jensen, Kim Bak, 2023, In: Gut Microbes. 15, 2, 16 p., 2281012.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Detecting selection in low-coverage high-throughput sequencing data using principal component analysis

    Meisner, Jonas, Albrechtsen, Anders & Hanghøj, Kristian Ebbesen, 2021, In: BMC Bioinformatics. 22, 13 p., 470.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Detecting sequence signals in targeting peptides using deep learning

    Almagro Armenteros, J. J., Salvatore, Marco, Emanuelsson, O., Winther, Ole, von Heijne, G., Elofsson, A. & Nielsen, H., 2019, In: Life Science Alliance. 2, 5, 14 p., 201900429.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Detection of Active Matriptase using a Biotinylated Chloromethyl Ketone Peptide

    Godiksen, S., Soendergaard, C., Friis, S., Jensen, J. K., Lange, Jette Bornholdt, Sales, K. U., Huang, M., Bugge, T. H. & Vogel, Lotte, 2013, In: P L o S One. 8, 10, 10 p., e77146.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Detection of Viable and Total Bacterial Community in the Pit Mud of Chinese Strong-Flavor Liquor Using Propidium Monoazide Combined With Quantitative PCR and 16S rRNA Gene Sequencing

    Tan, G., Zhou, R., Zhang, W., Hu, Y., Ruan, Z., Li, J., Zhang, C., Shen, D., Peng, N., Liang, Y. & Zhao, S., 2020, In: Frontiers in Microbiology. 11, 9 p., 896.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Detection of internal N7-methylguanosine (m7G) RNA modifications by mutational profiling sequencing

    Enroth, Christel Hougård, Poulsen, L. D., Iversen, S., Kirpekar, F., Albrechtsen, Anders & Vinther, Jeppe, 2019, In: Nucleic Acids Research. 47, 20, 13 p., e126.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Detection of reverse transcriptase termination sites using cDNA ligation and massive parallel sequencing

    Kielpinski, L. J., Boyd, M., Sandelin, Albin Gustav & Vinther, Jeppe, 2013, In: Methods in molecular biology (Clifton, N.J.). 1038, p. 213-31 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Detection of slicer activity by immunopurified plant ARGONAUTE1

    Arribas Hernandez, Laura, Vigh, Maria Louisa & Brodersen, Peter, 2019, Plant MicroRNAs: Methods and Protocols. Folter, S. D. (ed.). Humana Press, p. 295-316 22 p. (Methods in Molecular Biology, Vol. 1932).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  40. Published

    Determinants of enhancer and promoter activities of regulatory elements

    Andersson, Robin & Sandelin, Albin Gustav, 2020, In: Nature Reviews Genetics. 21, 2, p. 71-87 17 p.

    Research output: Contribution to journal › Review › Research › peer-review

  41. Published

    Development and Optimization of a Silica Column-Based Extraction Protocol for Ancient DNA

    Dehasque, M., Chrzanová Pecnerová, Patrícia, Kempe Lagerholm, V., Ersmark, E., Danilov, G. K., Mortensen, P., Vartanyan, S. & Dalén, L., 2022, In: Genes. 13, 4, 16 p., 687.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Diabetes in population isolates: lessons from Greenland

    Grarup, Niels, Moltke, Ida, Albrechtsen, Anders & Hansen, Torben, 2015, In: The Review of Diabetic Studies. 12, 3-4, p. 320-329 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  43. Published

    Differential expression of cellular microRNAs in HPV 11, -16, and -45 transfected cells

    Dreher, A., Rossing, M., Kaczkowski, B., Andersen, D. K., Larsen, T. J., Christophersen, M. K., Nielsen, Finn Cilius & Norrild, B., 2011, In: Biochemical and Biophysical Research Communications. 412, 1, p. 20-5 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Differential expression of cellular microRNAs in HPV-11 transfected cells. An analysis by three different array platforms and qRT-PCR

    Dreher, A., Rossing, M., Kaczkowski, B., Nielsen, Finn Cilius & Norrild, B., 17 Dec 2010, In: Biochemical and Biophysical Research Communications. 403, 3-4, p. 357-62 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Differential gene expression in the otic capsule and the middle ear-an annotation of bone-related signaling genes

    Nielsen, M. C., Martin-Bertelsen, T., Friis, M., Winther, Ole, Friis-Hansen, Lennart Jan, Rye-Jørgensen, N., Bloch, S. & Sørensen, Mads Sølvsten, 2015, In: Otology & Neurotology. 36, 4, p. 727-732 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    DiscoTope-3.0: improved B-cell epitope prediction using inverse folding latent representations

    Høie, M. H., Gade, F. S., Johansen, J., Würtzen, C., Winther, Ole, Nielsen, M. & Marcatili, P., 2024, In: Frontiers in Immunology. 15, 12 p., 1322712.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Discovering novel hydrolases from hot environments

    Wohlgemuth, R., Littlechild, J., Monti, D., Schnorr, K., van Rossum, T., Siebers, B., Menzel, P., Kublanov, I. V., Rike, A. G., Skretas, G., Szabo, Z., Peng, Xu & Young, M. J., 2018, In: Biotechnology Advances. 36, 8, p. 2077-2100

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network

    Grapotte, M., Saraswat, M., Bessière, C., Menichelli, C., Ramilowski, J. A., Severin, J., Hayashizaki, Y., Itoh, M., Tagami, M., Murata, M., Kojima-Ishiyama, M., Noma, S., Noguchi, S., Kasukawa, T., Hasegawa, A., Suzuki, H., Nishiyori-Sueki, H., Frith, M. C., Abugessaisa, I., Aitken, S. & 31 others, Aken, B. L., Alam, I., Alam, T., Alasiri, R., Alhendi, A. M. N., Alinejad-Rokny, H., Alvarez, M. J., Andersson, Robin, Arakawa, T., Araki, M., Arbel, T., Lange, Jette Bornholdt, Boyd, M., Chen, Y., Coskun, M., Dalby, M., Ienasescu, H., Jørgensen, M., Kaczkowski, B., Kere, J., Li, K., Lilje, B., Nepal, C., Nguyen, Q. H., Nielsen, L. K., Rennie, Sarah, Sandelin, Albin Gustav, Valen, E., Vitezic, M., Vitting-Seerup, K. & FANTOM Consortium, F. C., 2021, In: Nature Communications. 12, 18 p., 3297.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Discovery, genotyping and characterization of structural variation and novel sequence at single nucleotide resolution from de novo genome assemblies on a population scale

    Danish Pan Genome Consortium, D. P. G. C., Belling, K. G. & Rasmussen, Simon, 2015, In: GigaScience. 4, 13 p., 64.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Discrete structural dynamics of pseudo-palindromic motifs control DNA binding of bacterial toxin-antitoxin complexes

    Brodersen, D. E., Bendtsen, K. L., Xu, K., Luckmann, M., Winther, K. S., Shah, S. A. & Pedersen, C. N. S., 2017, In: F A S E B Journal. 31, S1, 1 p., 777.2.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  51. Published

    Disease-linked mutations cause exposure of a protein quality control degron

    Kampmeyer, Caroline, Larsen-Ledet, Sven, Wagnkilde, M. R., Michelsen, M., Iversen, Henriette Kring Mangor, Nielsen, S. V., Lindemose, Søren, Caregnato, A., Ravid, T., Stein, Amelie, Teilum, Kaare, Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2022, In: Structure. 30, 9, p. 1245-1253.e5

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Disorder in a two-domain neuronal Ca2+-binding protein regulates domain stability and dynamics using ligand mimicry

    Staby, L., Kemplen, K. R., Stein, Amelie, Ploug, Michael, Clarke, J., Skriver, Karen, Heidarsson, P. O. & Kragelund, Birthe Brandt, 2021, In: Cellular and molecular life sciences : CMLS. 78, p. 2263-2278 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Dispersal mediated coexistence of mud snails (Hydrobiidae) in an estuary

    Siegismund, Hans Redlef & Hylleberg, J., 1987, In: Marine Biology. 94, p. 395-402

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Dissecting the target specificity of RNase H recruiting oligonucleotides using massively parallel reporter analysis of short RNA motifs

    Rukov, J. L., Hagedorn, P. H., Høy, I. B., Feng, Y., Lindow, M. & Vinther, Jeppe, 2015, In: Nucleic Acids Research. 43, 17, p. 8476-8487 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    DivA: detection of non-homologous and very divergent regions in protein sequence alignments

    Zepeda Mendoza, M. L., Nygaard, S. & Rodrigues da Fonseca, Rute Andreia, 2014, In: BMC Research Notes. 7, 806, 6 p., 806.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Diverse bacterial genomes encode an operon of two genes, one of which is a unusual class-I release factor that potentially recognizes atypical mRNA signals other than normal stop codons

    Baranov, P., Vestergaard, Bente, Hamelryck, Thomas Wim, Gesteland, Nyborg, J. & Atking, J., 2006, In: Biology Direct. 13, p. 1-28 28 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Diversity and transboundary mobility of serotype O foot-and-mouth disease virus in East Africa: implications for vaccination policies

    Balinda, S., Sangula, A. K., Heller, Rasmus, Muwanika, V. B., Belsham, G., Masembe, C. & Siegismund, Hans Redlef, 1 Oct 2010, In: Infection, Genetics and Evolution. 10, 7, p. 1058-65 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Diversity of nature's assembly lines - recent discoveries in non-ribosomal peptide synthesis

    Payne, J. A. E., Schoppet, M., Hansen, M. H. & Cryle, M. J., 2017, In: Molecular BioSystems. 13, 1, p. 9-22 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Dominance of a clonal green sulfur bacterial population in a stratified lake

    Gregersen, Lea Haarup, Habicht, K. S., Peduzzi, S., Tonolla, M., Canfield, D. E., Miller, M., Cox, R. P. & Frigaard, Niels-Ulrik, 2009, In: FEMS Microbiology Ecology. 70, 1, p. 30-41 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Down-regulation of miR-129-5p and the let-7 family in neuroendocrine tumors and metastases leads to up-regulation of their targets Egr1, G3bp1, Hmga2 and Bach1

    Døssing, K. B. V., Binderup, Tina, Kaczkowski, B., Jacobsen, A. M. B., Rossing, M., Winther, O., Federspiel, B., Knigge, Ulrich, Kjær, Andreas & Friis-Hansen, L., 2015, In: Genes. 6, 1, p. 1-21 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Down-regulation of microRNAs controlling tumourigenic factors in follicular thyroid carcinoma

    Rossing, M., Helweg-Larsen, R. B., Henao Giraldo, R., Winther, Ole, Vikeså, J., Niazi, O., Godballe, C., Krogdahl, A., Glud, M., Sørensen, C. H., Kiss, K., Bennedbæk, F. N. & Nielsen, Finn Cilius, 2012, In: Journal of Molecular Endocrinology. 48, 1, p. 11-23 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    DoxoDB: A Database for the Expression Analysis of Doxorubicin-Induced lncRNA Genes

    Distefano, R., Ilieva, M., Madsen, J. H., Rennie, Sarah & Uchida, S., 2023, In: Non-coding RNA. 9, 4, 24 p., 39.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Drosha regulates gene expression independently of RNA cleavage function

    Gromak, N., Dienstbier, M., Macias, S., Plass, M., Eyras, E., Cáceres, J. F. & Proudfoot, N. J., 2013, In: Cell Reports. 5, 6, p. 1499-510 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Dwarfism and impaired gut development in insulin-like growth factor II mRNA-binding protein 1-deficient mice

    Hansen, Thomas van Overeem, Hammer, N. A., Nielsen, J., Madsen, Mette, Dalbaeck, C., Wewer, Ulla M., Christiansen, Jan & Nielsen, Finn Cilius, 2004, In: Molecular and Cellular Biology. 24, 10, p. 4448-64 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    ERG Controls B Cell Development by Promoting Igh V-to-DJ Recombination

    Søndergaard, E., Rauch, A., Michaut, Magali, Rapin, N., Rehn, M., Wilhelmson, Anna, Camponeschi, A., Hasemann, M. S., Bagger, F. O., Jendholm, J., Knudsen, K. J., Mandrup, S., Mårtensson, I. L. & Porse, Bo Torben, 26 Nov 2019, In: Cell Reports. 29, 9, p. 2756-2769.e6 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    ERG promotes the maintenance of hematopoietic stem cells by restricting their differentiation

    Knudsen, K. J., Rehn, M. C., Hasemann, M. S., Rapin, N. P. J., Bagger, F. O., Ohlsson, E. K., Willer, A., Frank, Anne-Katrine, Søndergaard, E., Jendholm, L. J., Thorén, L. A. M., Lee, J., Rak, J., Theilgaard-Mønch, Kim & Porse, Bo Torben, 2015, In: Genes & Development. 29, p. 1915-1929 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas

    Mohammad, F., Weissmann, S., Leblanc, B. O., Pandey, D. P., Højfeldt, J. W., Comet, I., Zheng, C., Johansen, Jens Vilstrup, Rapin, N. P. J., Porse, Bo Torben, Tvardovskiy, A., Jensen, O. N., Olaciregui, N. G., Lavarino, C., Suñol, M., de Torres, C., Mora, J., Carcaboso, A. M. & Helin, K., Apr 2017, In: Nature Medicine. 23, 4, p. 483-492 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    EasyGene - a prokaryotic gene finder that ranks ORFs by statistical significance

    Larsen, T. S. & Krogh, Anders, 2003, In: BMC Bioinformatics. 4(1), p. 21

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Editorial: Long-read sequencing—Pitfalls, benefits and success stories

    Wohlers, I., Garg, S. & Hehir-Kwa, J. Y., 2023, In: Frontiers in Genetics. 13, 3 p., 1114542.

    Research output: Contribution to journal › Editorial › Research › peer-review

  70. Published

    Effect of alkaline treatment on bacteriochlorophyll a, quinones, and energy transfer in chlorosomes from Chlorobium tepidum and Chlorobium phaeobacteroides

    van Walree, C. A., Sakuragi, Y., Steensgaard, D. B., Bösinger, C. S., Frigaard, Niels-Ulrik, Cox, R. P., Holzwarth, A. R. & Miller, M., 1999, In: Photochemistry and Photobiology. 69, p. 322-328 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Effect of chronic uremia on the transcriptional profile of the calcified aorta analyzed by RNA sequencing

    Rukov, J. L., Gravesen, Eva, Mace, M. L., Hofman-Bang, J., Vinther, Jeppe, Andersen, C. B., Lewin, E. & Ølgaard, Klaus, 2016, In: American Journal of Physiology: Renal Physiology. 310, 6, p. F477-F491 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Effect of ecological and anthropogenic factors on grouping patterns in African lions across Kenya

    Chege, M., Bertola, Laura, De Snoo, G. R., Ngene, S., Otieno, T., Amoke, I., van 't Zelfde, M., Dolrenry, S., Broekhuis, F., Tamis, W., De Iongh, H. H. & Elliot, N. B., 2024, In: Ecology and Evolution. 14, 2, 14 p., e10982.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Effect of energy metabolism on protein motility in the bacterial outer membrane

    Ryder, T. W., Xu, L., Berg-Sørensen, K., Brown, Stanley & Oddershede, L. B., 2009, In: Biophysical Journal. 97, 5, p. 1305-1312 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Effect of supercoiling on the λ switch

    Norregaard, K., Andersson, M., Sneppen, Kim, Nielsen, Peter E., Brown, Stanley & Oddershede, L. B., 1 Jan 2014, In: Bacteriophage. 4, 2, p. 1-5 5 p., e27517.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Effects of Four Different Regulatory Mechanisms on the Dynamics of Gene Regulatory Cascades

    Hansen, S., Krishna, S., Semsey, S. & Svenningsen, Sine Lo, 17 Jul 2015, In: Scientific Reports. 5, 12186.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Efficient Generative Modelling of Protein Structure Fragments using a Deep Markov Model

    Thygesen, Christian Bahne, Al-Sibahi, A. S., Steenmanns, C. S., Sanz Moreta, Lys, Sørensen, A. B. & Hamelryck, Thomas Wim, 2021, International Conference on Machine Learning, 18-24 July 2021, Virtual. PMLR, p. 10258-10267 (Proceedings of Machine Learning Research, Vol. 139).

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

  77. Published

    Efficient approaches for large-scale GWAS with genotype uncertainty

    Jørsboe, E. & Albrechtsen, Anders, 2022, In: G3: Genes, Genomes, Genetics (Bethesda). 12, 1, 9 p., jkab385.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Efficient statistical and computational methods for large scale sequencing data

    Li, Zilong, 2024, Department of Biology, Faculty of Science, University of Copenhagen. 149 p.

    Research output: Book/Report › Doctoral thesis › Research

  79. Published

    Efficient, non-disruptive local moves for Monte Carlo sampling of proteins

    Bottaro, S., Boomsma, Wouter, Johansson, Kristoffer Enøe, Andreetta, C., Hamelryck, Thomas Wim & Ferkinghoff-Borg, J., 2011, Next Generation Statistics in Biosciences: Proceedings of the 30th Leeds Annual Statistical Research (LASR) Workshop. Mardia, K. V., Gusnanto, A., Riley, A. D. & Voss, J. (eds.). University of Leeds, p. 127 1 p.

    Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Research

  80. Published

    Eight millennia of matrilineal genetic continuity in the South Caucasus

    Margaryan, Ashot, Derenko, M., Hovhannisyan, H., Malyarchuk, B., Heller, Rasmus, Khachatryan, Z., Avetisyan, P., Badalyan, R., Bobokhyan, A., Melikyan, V., Sargsyan, G., Piliposyan, A., Simonyan, H., Mkrtchyan, R., Denisova, G., Yepiskoposyan, L., Willerslev, Eske & Allentoft, Morten Erik, 10 Jul 2017, In: Current Biology. 27, 13, p. 2023-2028 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Electronic energy transfer involving carotenoid pigments in chlorosomes of two green bacteria: Chlorobium tepidum and Chloroflexus aurantiacus

    Melø, T. B., Frigaard, Niels-Ulrik, Matsuura, K. & Razi Naqvi, K., 2000, In: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 56, 10, p. 2001-2010 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Embryonic expression of Drosophila IMP in the developing CNS and PNS

    Adolph, S. K., Delotto, R., Nielsen, Finn Cilius & Christiansen, Jan, 2008, In: Gene Expression Patterns. 9, 3, p. 138-143 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Emergence and radiation of distemper viruses in terrestrial and marine mammals

    Stokholm, Iben, Puryear, W., Sawatzki, K., Knudsen, Steen Wilhelm, Terkelsen, Thilde Bagger, Becher, P., Siebert, U. & Olsen, Morten Tange, 2021, In: Proceedings of the Royal Society B: Biological Sciences. 288, 1961, 9 p., 20211969.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Endogenous retroviruses co-opted as divergently transcribed regulatory elements shape the regulatory landscape of embryonic stem cells

    Bakoulis, Stylianos, Krautz, Robert, Alcaraz, N., Salvatore, Marco & Andersson, Robin, 2022, In: Nucleic acids symposium series. 50, 4, p. 2111-2127 17 p., 088.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Engineered iron oxide adhesion mutants of the lambda-receptor

    Brown, Stanley, 1992, In: Proceedings of the National Academy of Science of the United States of America. 89, p. 8651-8655

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Enhancer and Transcription Factor Dynamics during Myeloid Differentiation Reveal an Early Differentiation Block in Cebpa null Progenitors

    Pundhir, Sachin, Bratt Lauridsen, F. K., Schuster, Mikkel Bruhn, Jakobsen, J. S., Ge, Y., Schoof, E. M., Rapin, N. P. J., Waage, J., Hasemann, M. S. & Porse, Bo Torben, 2018, In: Cell Reports. 23, 9, p. 2744-2757 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Enhancing CRISPR-Cas9 gRNA efficiency prediction by data integration and deep learning

    Xiang, X., Corsi, G. I., Anthon, C., Qu, K., Pan, X., Liang, X., Han, P., Dong, Z., Liu, L., Zhong, J., Ma, T., Wang, J., Zhang, X., Jiang, H., Xu, F., Liu, X., Xu, X., Wang, J., Yang, H., Bolund, L. & 4 others, Church, G. M., Lin, L., Gorodkin, Jan & Luo, Y., 2021, In: Nature Communications. 12, 1, 9 p., 3238.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Enterococcus faecalis infection causes inflammation, intracellular oxphos-independent ROS production, and DNA damage in human gastric cancer cells

    Strickertsson, J. A. B., Desler, Claus, Martin-Bertelsen, T., Machado, A. M. D., Wadstrøm, T., Winther, Ole, Rasmussen, Lene Juel & Friis-Hansen, Lennart Jan, 2013, In: PLOS ONE. 8, 4, p. 1-13 13 p., e63147.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Equilibrium simulations of proteins using molecular fragment replacement and NMR chemical shifts

    Boomsma, Wouter, Tian, P., Frellsen, J., Ferkinghoff-Borg, J., Hamelryck, Thomas Wim, Lindorff-Larsen, Kresten & Vendruscolo, M., 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 38, p. 13852-13857 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Error-prone polymerase activity causes multinucleotide mutations in humans

    Harris, K. & Nielsen, Rasmus, 1 Sep 2014, In: Genome Research. 24, 9, p. 1445-1454 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Escherichia coli phnN, encoding ribose 1,5-bisphosphokinase activity (phosphoribosyl diphosphate forming): dual role in phosphonate degradation and NAD biosynthesis pathways.

    Hove-Jensen, B., Rosenkrantz, T. J., Haldimann, A. & Wanner, B. L., 2003, In: Journal of Bacteriology. 185, 9, p. 2793-801 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Estimating IBD tracts from low coverage NGS data

    Vieira, Filipe Garrett, Albrechtsen, Anders & Nielsen, Rasmus, 2016, In: Bioinformatics. 32, 14, p. 2096-2102 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Estimating admixture pedigrees of recent hybrids without a contiguous reference genome

    Garcia Erill, Genís, Hanghøj, Kristian Ebbesen, Heller, Rasmus, Wiuf, Carsten & Albrechtsen, Anders, 2023, In: Molecular Ecology Resources. 23, 7, p. 1604-1619 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Estimating inbreeding coefficients from NGS data: impact on genotype calling and allele frequency estimation

    Vieira, Filipe Garrett, Fumagalli, M., Albrechtsen, Anders & Nielsen, Rasmus, 2013, In: Genome Research. 23, p. 1852-1861 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Estimating individual admixture proportions from next generation sequencing data

    Skotte, L., Korneliussen, Thorfinn Sand & Albrechtsen, Anders, Nov 2013, In: Genetics. 195, 3, p. 693-702 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Estimating narrow-sense heritability using family data from admixed populations

    Athanasiadis, G., Speed, D., Lepola, Mette Andersen, Appel, E. V. R., Grarup, Niels, Brandslund, I., Jørgensen, M. E., Larsen, C. V. L., Bjerregaard, P., Hansen, Torben & Albrechtsen, Anders, 2020, In: Heredity. 124, 6, p. 751-762 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Estimating the timing of multiple admixture pulses during local ancestry inference

    Medina, P., Thornlow, B., Nielsen, Rasmus & Corbett-Detig, R., 2018, In: Genetics. 210, 3, p. 1089-1107 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Estimation of allele frequency and association mapping using next-generation sequencing data

    Kim, S. Y., Lohmueller, K. E., Albrechtsen, Anders, Li, Y., Korneliussen, Thorfinn Sand, Tian, G., Grarup, Niels, Jiang, T., Andersen, G., Witte, D., Jorgensen, T., Hansen, Torben, Pedersen, Oluf Borbye, Wang, J. & Nielsen, Rasmus, 2011, In: B M C Bioinformatics. 12, p. 231 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Estimation of site frequency spectra from low-coverage sequencing data using stochastic EM reduces overfitting, runtime, and memory usage

    Rasmussen, Malthe Sebro, Garcia Erill, Genís, Korneliussen, Thorfinn Sand, Wiuf, Carsten & Albrechtsen, Anders, 2022, In: Genetics. 222, 4, 15 p., iyac148.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Estimation of the covariance structure from SNP allele frequencies

    van Waaij, J., Li, Z. & Wiuf, Carsten, 2022, In: Statistical Applications in Genetics and Molecular Biology. 21, 1, 20 p., 20220005.

    Research output: Contribution to journal › Journal article › Research › peer-review

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