- 2019
- Published
More grist for the mill? Species delimitation in the genomic era and its implications for conservation
Stanton, D. W. G., Frandsen, P., Waples, R. K., Heller, Rasmus, Russo, I. M., Orozco-terWengel, P. A., Pedersen, C. T., Siegismund, Hans Redlef & Bruford, M. W., 2019, In: Conservation Genetics. 20, 1, p. 101-113Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML
Jakobsen, J. S., Laursen, L. G., Schuster, Mikkel Bruhn, Pundhir, Sachin, Schoof, E., Ge, Y., d'Altri, T., Vitting-Seerup, K., Rapin, N., Gentil, C., Jendholm, J., Theilgaard-Mønch, Kim, Reckzeh, K., Bullinger, L., Döhner, K., Hokland, P., Fitzgibbon, J. & Porse, Bo Torben, 2019, In: Science Advances. 5, 7, p. 1-16 16 p., eaaw4304.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NetSurfP-2.0: improved prediction of protein structural features by integrated deep learning
Klausen, M. S., Jespersen, M. C., Nielsen, H., Jensen, K. K., Jurtz, V. I., Sønderby, C. K., Sommer, M. O. A., Winther, Ole, Nielsen, M., Petersen, Bent & Marcatili, P., 2019, In: Proteins: Structure, Function and Bioinformatics. 87, 6, p. 520-527Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells
Agrawal-Singh, S., Lerdrup, Mads, Gomes, A. R., van de Werken, H. J. G., Johansen, Jens Vilstrup, Andersson, Robin, Sandelin, Albin Gustav, Helin, K. & Hansen, K., 2019, In: eLife. 8, p. 1-32 32 p., e40364.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Predicted highly derived class 1 CRISPR-Cas system in Haloarchaea containing diverged Cas5 and Cas7 homologs but no CRISPR array
Makarova, K. S., Karamycheva, S., Shah, S. A., Vestergaard, G. A., Garrett, Roger Antony & Koonin, E. V., 2019, In: FEMS Microbiology Letters. 366, 7, 5 p., fnz079.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Probabilistic methods for the analysis of genome-wide data for admixed populations including association studies in Greenlandic Inuit
Jørsboe, E., 2019, Department of Biology, Faculty of Science, University of Copenhagen.Research output: Book/Report › Ph.D. thesis › Research
- Published
Relatedness, admixture and the genetic history of Greenland-European contact
Waples, R., 2019, Department of Biology, Faculty of Science, University of Copenhagen.Research output: Book/Report › Ph.D. thesis › Research
- Published
Sensitive detection of circular DNAs at single-nucleotide resolution using guided realignment of partially aligned reads
Prada Luengo, Inigo, Krogh, Anders, Sørensen, L. M. & Regenberg, Birgitte, 2019, In: BMC Bioinformatics. 20, 9 p., 663.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single mRNP Analysis Reveals that Small Cytoplasmic mRNP Granules Represent mRNA Singletons
Mateu-Regué, À., Christiansen, Jan, Bagger, F. O., Winther, O., Hellriegel, C. & Nielsen, Finn Cilius, 2019, In: Cell Reports. 29, 3, p. 736-748, e1-e4Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Testing for Hardy-Weinberg equilibrium in structured populations using genotype or low-depth next generation sequencing data
Meisner, Jonas & Albrechtsen, Anders, 2019, In: Molecular Ecology Resources. 19, 5, p. 1144-1152 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The epigenetic factor BORIS (CTCFL) controls the androgen receptor regulatory network in ovarian cancer
Salgado-Albarrán, M., González-Barrios, R., Guerra-Calderas, L., Alcaraz, N., Sánchez-Correa, T. E., Castro-Hernández, C., Sánchez-Pérez, Y., Aréchaga-Ocampo, E., García-Carrancá, A., de León, D. C., Herrera, L. A., Baumbach, J. & Soto-Reyes, E., 2019, In: Oncogenesis. 8, 12 p., 41.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The splicing factor RBM25 controls MYC activity in acute myeloid leukemia
Ge, Y., Schuster, Mikkel Bruhn, Pundhir, Sachin, Rapin, N., Bagger, F. O., Sidiropoulos, N., Hashem, N. & Porse, Bo Torben, 2019, In: Nature Communications. 10, 1, p. 1-14 14 p., 172.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The transmembrane autophagy cargo receptors ATI1 and ATI2 interact with ATG8 through intrinsically disordered regions with distinct biophysical properties
Sjøgaard, Ida Marie Zobbe, Bressendorff, Simon, Prestel, Andreas, Kausika, S., Oksbjerg, Emilie Duus, Kragelund, Birthe Brandt & Brodersen, Peter, 2019, In: Biochemical Journal. 476, 3, p. 449-465 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Circular DNA elements of chromosomal origin are common in healthy human somatic tissue
Møller, H. D., Mohiyuddin, M., Prada Luengo, Inigo, Sailani, M. R., Halling, Jens Frey, Plomgaard, Peter Stendahl, Maretty, L., Hansen, Anders Johannes, Snyder, M. P., Pilegaard, Henriette, Lam, H. Y. K. & Regenberg, Birgitte, 1 Dec 2018, In: Nature Communications. 9, 12 p., 1069.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits
Gilly, A., Suyeges, D., Kuchenbaecker, K., Pollard, M., Southam, L., Hatzikotoulas, K., Farmaki, A-E., Bjornland, T., Waples, R., Appel, E. V. R., Casalone, E., Melloni, G., Kilian, B., Rayner, N. W., Ntalla, I., Kundu, K., Walter, K., Danesh, J., Butterworth, A., Barroso, I. & 5 others, , 1 Dec 2018, In: Nature Communications. 9, p. 1-9 4674.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FoxA1 in synergy with IFNβ controls PDL1 expression in anti-inflammatory T cells via binding to a 60-nucleotide region in the Pdl1 promoter
Hadi, M., Rasmussen, L. M., Kosicki, M., Carlsson, R. & Issazadeh-Navikas, Shohreh, Oct 2018, p. 596-597.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population
Grarup, Niels, Moltke, Ida, Lepola, Mette Andersen, Bjerregaard, P., Larsen, C. V. L., Dahl-Petersen, I. K., Jørsboe, E., Tiwari, H. K., Hopkins, S. E., Wiener, H. W., Boyer, B. B., Linneberg, Allan René, Pedersen, Oluf Borbye, Jørgensen, M. E., Albrechtsen, Anders & Hansen, Torben, 1 Sep 2018, In: Diabetologia. 61, 9, p. 2005–2015Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome sequence and effectorome of Moniliophthora perniciosa and Moniliophthora roreri subpopulations
Barbosa, C. S., Rodrigues da Fonseca, Rute Andreia, Batista, T. M., Barreto, M. A., Argolo, C. S., de Carvalho, M. R., Jordao do Amaral, D. O., de Andrade Silva, E. M., Arevalo-Gardini, E., Hidalgo, K. S., Franco, G. R., Pirovani, C. P., Micheli, F. & Gramacho, K. P., 3 Jul 2018, In: BMC Genomics. 19, 12 p., 509.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
- Published
YeastFab: High-Throughput Genetic Parts Construction, Measurement, and Pathway Engineering in Yeast
Garcia-Ruiz, E., Auxillos, Jamie Yam, Li, T., Dai, J. & Cai, Y., 1 Jan 2018, Methods in Enzymology. Scrutton, N. (ed.). Academic Press, p. 277-306 30 p. (Methods in Enzymology, Vol. 608).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
"Out of the Can": A Draft Genome Assembly, Liver Transcriptome, and Nutrigenomics of the European Sardine, Sardina pilchardus
Machado, A. M., Tørresen, O. K., Kabeya, N., Couto, A., Petersen, Bent, Felicio, M., Campos, P. F., Fonseca, E., Bandarra, N., Lopes-Marques, M., Ferraz, R., Ruivo, R., Fonseca, M. M., Jentoft, S., Monroig, Ó., Rodrigues da Fonseca, Rute Andreia & Castro, L. F. C., 2018, In: Genes. 9, 10, p. 1-13 485.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A new class of genic nuclear RNA species in Arabidopsis
van Wonterghem, M., Thieffry, A., Boyd, M., Lange, Jette Bornholdt & Brodersen, Peter, 2018, In: FEBS Letters. 592, 4, p. 631-643 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A resource for sustainable management: De novo assembly and annotation of the liver transcriptome of the Atlantic chub mackerel, Scomber colias
Machado, A. M., Felício, M., Fonseca, E., Rodrigues da Fonseca, Rute Andreia & Castro, L. F. C., 2018, In: Data in Brief. 18, p. 276-284 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A southern African origin and cryptic structure in the highly mobile plains zebra
Pedersen, C. T., Albrechtsen, Anders, Etter, P. D., Johnson, E. A., Orlando, L., Chikhi, L., Siegismund, Hans Redlef & Heller, Rasmus, 2018, In: Nature Ecology & Evolution. 2, 3, p. 491-498 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Accurate genotyping across variant classes and lengths using variant graphs
Sibbesen, Jonas Andreas, Maretty, L., Krogh, Anders, Petersen, Bent, Sibbesen, Jonas Andreas, Liu, S., Have, C. T., Bork-Jensen, J., Guo, X., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Wang, J. & Brunak, Søren, 2018, In: Nature Genetics. 50, p. 1054-1059 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An m6A-YTH Module Controls Developmental Timing and Morphogenesis in Arabidopsis
Arribas Hernandez, Laura, Bressendorff, Simon, Hansen, M. H., Poulsen, C., Erdmann, S. & Brodersen, Peter, 2018, In: Plant Cell. 30, 5, p. 952-967 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancient genomes revisit the ancestry of domestic and Przewalski's horses
Gaunitz, C., Fages, A. A., Hanghøj, K. E., Albrechtsen, A., Khan, N., Schubert, M., Seguin-Orlando, A., Owens, I. J., Felkel, S., Bignon-Lau, O., Damgaard, P. D. B., Mittnik, A., Mohaseb, A. F., Davoudi, H., Alquraishi, S., Alfarhan, A. H., Al-Rasheid, K. A. S., Crubézy, E., Benecke, N., Olsen, S. & 27 others, , 2018, In: Science. 360, 6384, p. 111-114 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Benchmarking the HLA typing performance of Polysolver and Optitype in 50 Danish parental trios
Matey-Hernandez, M. L., Danish Pan Genome Consortium, D. P. G. C., Brunak, Søren, Izarzugaza, J. M. G., Sørensen, L. M., Petersen, Bent, Sibbesen, Jonas Andreas, Liu, S., Belling, K. G., Have, C. T., Bork-Jensen, J., Sun, J., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Wang, J., Eiberg, Hans Rudolf Lytchoff & Kristiansen, Karsten, 2018, In: BMC Bioinformatics. 19, p. 1-12 239.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Binning microbial genomes using deep learning
Nissen, J. N., Sønderby, C. K., Armenteros, J. J. A., Grønbech, Christopher Heje, Nielsen, H. B., Petersen, T. N., Winther, Ole & Rasmussen, Simon, 2018, (bioRxiv).Research output: Working paper › Preprint › Research
- Published
CTCF-KDM4A complex correlates with histone modifications that negatively regulate CHD5 gene expression in cancer cell lines
Guerra-Calderas, L., González-Barrios, R., Patiño, C. C., Alcaraz, N., Salgado-Albarrán, M., de León, D. C., Hernández, C. C., Sánchez-Pérez, Y., Maldonado-Martínez, H. A., De la Rosa-Velazquez, I. A., Vargas-Romero, F., Herrera, L. A., García-Carrancá, A. & Soto-Reyes, E., 2018, In: OncoTarget. 9, 24, p. 17028-17042 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies
Boyd, M., Thodberg, M., Vitezic, M., Lange, J. B., Vitting-Seerup, K., Chen, Y., Coskun, M., Li, Y., Lo, B. Z. S., Klausen, P., Schweiger, P., Pedersen, A. G., Rapin, N. P. J-P., Skovgaard, K., Dahlgaard, K., Andersson, R., Terkelsen, T. B., Lilje, B., Troelsen, J. T., Petersen, A. M. & 7 others, , 2018, In: Nature Communications. 9, 19 p., 1661.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of the human RFX transcription factor family by regulatory and target gene analysis
Sugiaman-Trapman, D., Vitezic, M., Jouhilahti, E., Mathelier, A., Lauter, G., Misra, S., Daub, C. O., Kere, J. & Swoboda, P., 2018, In: BMC Genomics. 19, 15 p., 181.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovering novel hydrolases from hot environments
Wohlgemuth, R., Littlechild, J., Monti, D., Schnorr, K., van Rossum, T., Siebers, B., Menzel, P., Kublanov, I. V., Rike, A. G., Skretas, G., Szabo, Z., Peng, Xu & Young, M. J., 2018, In: Biotechnology Advances. 36, 8, p. 2077-2100Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enhancer and Transcription Factor Dynamics during Myeloid Differentiation Reveal an Early Differentiation Block in Cebpa null Progenitors
Pundhir, Sachin, Bratt Lauridsen, F. K., Schuster, Mikkel Bruhn, Jakobsen, J. S., Ge, Y., Schoof, E. M., Rapin, N. P. J., Waage, J., Hasemann, M. S. & Porse, Bo Torben, 2018, In: Cell Reports. 23, 9, p. 2744-2757 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimating the timing of multiple admixture pulses during local ancestry inference
Medina, P., Thornlow, B., Nielsen, Rasmus & Corbett-Detig, R., 2018, In: Genetics. 210, 3, p. 1089-1107 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploring the central dogma from both ends. Omics integration of Hi-C sequencing and Raman spectroscopic data
Kumar, V., 2018, Department of Biology, Faculty of Science, University of Copenhagen.Research output: Book/Report › Ph.D. thesis › Research
- Published
Farnesylated heat shock protein 40 is a component of membrane-bound RISC in Arabidopsis
Sjögren, L., Floris, M., Barghetti, A., Völlmy, F., Linding, R. & Brodersen, Peter, 2018, In: Journal of Biological Chemistry. 293, 43, p. 16608-16622Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic architecture of obesity and related metabolic traits - recent insights from isolated populations
Lepola, Mette Andersen, Grarup, Niels, Moltke, Ida, Albrechtsen, Anders & Hansen, Torben, 2018, In: Current Opinion in Genetics and Development. 50, p. 74-78 5 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Genetic determinants of glycated hemoglobin levels in the Greenlandic Inuit population
Appel, V. R., Moltke, Ida, Jørgensen, M. E., Bjerregaard, P., Linneberg, Allan René, Pedersen, Oluf Borbye, Albrechtsen, Anders, Hansen, Torben & Grarup, Niels, 2018, In: European Journal of Human Genetics. 26, 6, p. 868-875 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic Analyses from Non-invasive Prenatal Testing Reveal Genetic Associations, Patterns of Viral Infections, and Chinese Population History
Liu, S., Huang, S., Chen, F., Zhao, L., Yuan, Y., Francis, S. S., Fang, L., Li, Z., Lin, L., Liu, R., Zhang, Y., Xu, H., Li, S., Zhou, Y., Davies, R. W., Liu, Q., Walters, R. G., Lin, K., Ju, J., Komeliussen, T. & 18 others, , 2018, In: Cell. 175, 2, p. 347-359, e1-e7Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic insights into early maritime adaptations in Western Patagonia
jxb425, jxb425, Moreno Mayar, J. Víctor, Alfonso-Durruty, M., Morello, F., Vilar, M., Wells, S., Campos, P. & Willerslev, Eske, 2018, p. 64. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Genomic insights into the origin and diversification of late maritime hunter-gatherers from the Chilean Patagonia
De la Fuente, C., Avila-Arcos, M. C., Galimany, J., Carpenter, M. L., Homburger, J. R., Blanco, A., Contreras, P., Davalos, D. C., Reyes, O., Roman, M. S., Moreno-Estrada, A., Campos, P., Eng, C., Huntsman, S., Burchard, E. G., Malaspinas, A-S., Bustamante, C. D., Willerslev, E., Llop, E., Verdugo, R. A. & 1 others, , 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 17, p. E4006-E4012 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic investigations of horse domestication using ancient DNA and a novel statistical method for epigenomic inference from ancient DNA sequencing data
Hanghøj, Kristian Ebbesen, 2018, Department of Biology, Faculty of Science, University of Copenhagen.Research output: Book/Report › Ph.D. thesis › Research
- Published
High definition urban fashion: Proteins reveal preferred resources for medieval leather shoes
Brandt, Luise Ørsted, 2018, Urban Network Evolutions: Towards a high-definition archaeology. Aarhus: Aarhus University Press, p. 241-247 7 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Human adult HSCs can be discriminated from lineage-committed HPCs by the expression of endomucin
Reckzeh, K., Kizilkaya, Hüsün Sheyma, Helbo, A. S., Estruch Alrich, Montserrat, Deslauriers, A. G., Grover, A., Rapin, N., Asmar, F., Grønbæk, Kirsten, Porse, Bo Torben, Borregaard, N., Vestweber, D., Nerlov, C. & Theilgaard-Mønch, Kim, 2018, In: Blood advances. 2, 13, p. 1628-1632 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inference and Learning in Deep Generative Models
Sønderby, C. K., 2018, Department of Biology, Faculty of Science, University of Copenhagen.Research output: Book/Report › Ph.D. thesis › Research
- Published
Inferring Population Structure and Admixture Proportions in Low-Depth NGS Data
Meisner, Jonas & Albrechtsen, Anders, 2018, In: Genetics. 210, 2, p. 719-731Research output: Contribution to journal › Journal article › Research › peer-review
- Published
JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework
Khan, A., Fornes, O., Stigliani, A., Gheorghe, M., Castro-Mondragon, J. A., van der Lee, R., Bessy, A., Chèneby, J., Kulkarni, S. R., Tan, G., Baranasic, D., Arenillas, D. J., Sandelin, Albin Gustav, Vandepoele, K., Lenhard, B., Ballester, B., Wasserman, W. W., Parcy, F. & Mathelier, A., 2018, In: Nucleic Acids Research. 46, D1, p. D260-D266 7 p., gkx1126.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Jagten på antikkens bindemidler
Brandt, Luise Ørsted, 2018, In: Sfinx. 41, 1, p. 26-29 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes
Grarup, Niels, Moltke, Ida, Lepola, Mette Andersen, Dalby, M., Vitting-Seerup, K., Kern, T. S., Mahendran, Y., Jørsboe, E., Larsen, C. V. L., Dahl-Petersen, I. K., Gilly, A., Suveges, D., Dedoussis, G., Zeggini, E., Pedersen, Oluf Borbye, Andersson, Robin, Bjerregaard, P., Jørgensen, M. E., Albrechtsen, Anders & Hansen, Torben, 2018, In: Nature Genetics. 50, 2, p. 172-174 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MCM2 promotes symmetric inheritance of modified histones during DNA replication
Petryk, N., Dalby, M., Wenger, Alice, Stromme, C. B., Strandsby, A., Andersson, Robin & Groth, Anja, 2018, In: Science. 361, 6409, p. 1389-1392 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MyPMFs: a simple tool for creating statistical potentials to assess protein structural models
Postic, G., Hamelryck, Thomas Wim, Chomilier, J. & Stratmann, D., 2018, In: Biochimie. 151, p. 37-41 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oral health status in historic population: Macroscopic and metagenomic evidence
Willmann, C., Mata, X., Hanghøj, Kristian Ebbesen, Tonasso, L., Tisseyre, L., Jeziorski, C., Cabot, E., Chevet, P., Crubézy, E., Orlando, L., Esclassan, R., Thèves, C. & Caramelli, D., 2018, In: PLOS ONE. 13, 5, 18 p., e0196482.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Organism- and disease-specific atlases of transcription start sites using Cap Analysis of Gene Expression (CAGE)
Thodberg, Malte, 2018, Department of Biology, Faculty of Science, University of Copenhagen.Research output: Book/Report › Ph.D. thesis › Research
- Published
Orthologous proteins of experimental de- and remyelination are differentially regulated in the CSF proteome of multiple sclerosis subtypes
Martin, N. A., Nawrocki, A., Molnar, V., Elkjaer, M. L., Thygesen, E. K., Palkovits, M., Acs, P., Sejbaek, T., Nielsen, H. H., Hegedus, Z., Sellebjerg, Finn Thorup, Molnar, T., Barbosa, E. G. V., Alcaraz, N., Gallyas, F. J., Svenningsen, A. F., Baumbach, J., Lassmann, H., Larsen, M. R. & Illes, Z., 2018, In: PLOS ONE. 13, 8, p. 1-26 e0202530.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physiological and Genetic Adaptations to Diving in Sea Nomads
Ilardo, M. A., Moltke, Ida, Korneliussen, Thorfinn Sand, Cheng, J., Stern, A. J., Racimo, Fernando, Damgaard, P. D. B., Sikora, Martin, Seguin-Orlando, A., Rasmussen, Simon, van den Munckhof, I. C. L., ter Horst, R., Joosten, L. A. B., Netea, M. G., Salingkat, S., Nielsen, Rasmus & Willerslev, Eske, 2018, In: Cell. 173, 3, p. 569-580 12 p., e15.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Powerful Inference With the D-Statistic on Low-Coverage Whole-Genome Data
Soraggi, S., Wiuf, Carsten & Albrechtsen, Anders, 2018, In: G3: Genes, Genomes, Genetics (Bethesda). 8, 2, p. 551-566Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Probabilistic Programming for Voucher Information Extraction: Preliminary Practical Experiences
Al-Sibahi, A. S., Hamelryck, Thomas Wim & Henglein, Fritz, 2018.Research output: Contribution to conference › Poster › Research
- Published
RNA-Seq for Bacterial Gene Expression
Poulsen, L. D. & Vinther, Jeppe, 2018, In: Current Protocols in Nucleic Acid Chemistry. 73, 1, p. 1-12 e55.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation and Maintenance of Transcriptional Specificity
Dalby, M., 2018, Department of Biology, Faculty of Science, University of Copenhagen.Research output: Book/Report › Ph.D. thesis › Research
- Published
Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease
Baillie, J. K., Bretherick, A., Haley, C. S., Clohisey, S., Gray, A., Neyton, L. P. A., Barrett, J., Stahl, E. A., Tenesa, A., Andersson, R., Brown, J. B., Faulkner, G. J., Lizio, M., Schaefer, U., Daub, C., Itoh, M., Kondo, N., Lassmann, T., Kawai, J., Mole, D. & 14 others, , 2018, In: PLoS Computational Biology. 14, 3, 24 p., e1005934.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SinaPlot: an enhanced chart for simple and truthful representation of single observations over multiple classes
Sidiropoulos, N., Sohi, S. H., Pedersen, T. L., Porse, Bo Torben, Winther, Ole, Rapin, N. & Bagger, F. O., 2018, In: Journal of Computational and Graphical Statistics. 27, 3, p. 673-676 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Skind og Ben - Forskning med fokus på dyr fra middelalderens Odense
Brandt, Luise Ørsted, Amsgaard Ebsen, J. & Haase, K., 2018Research output: Non-textual form › Interactive production › Communication
- Published
Terminal Pleistocene Alaskan genome reveals first founding population of Native Americans
Moreno Mayar, J. Víctor, Potter, B. A., Vinner, Lasse, Steinrucken, M., Rasmussen, Simon, Terhorst, J., Kamm, J. A., Albrechtsen, Anders, Malaspinas, A., Sikora, Martin, Reuther, J. D., Irish, J. D., Malhi, R. S., Orlando, L. A. A., Song, Y. S., Nielsen, Rasmus, Meltzer, D. J. & Willerslev, Eske, 2018, In: Nature Genetics. 553, 7687, p. 203-207 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
The GBAF chromatin remodeling complex binds H3K27ac and mediates enhancer transcription
Jefimov, K., Alcaraz, N., Kloet, S. L., Värv, S., Sakya, S. A., Vaagenso, C., Vermeulen, M., Aasland, R. & Andersson, Robin, 2018, 31 p.Research output: Working paper › Preprint › Research
- Published
The Muskox Lost a Substantial Part of Its Genetic Diversity on Its Long Road to Greenland
Hansen, C. C. R., Hvilsom, C., Schmidt, N. M., Aastrup, P., de Groot, P. J. V. C., Siegismund, Hans Redlef & Heller, Rasmus, 2018, In: Current Biology. 28, 24, p. 4022-4028, e1-e5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer
Pastuzyn, E. D., Day, C. E., Kearns, R. B., Kyrke-Smith, M., Taibi, A. V., McCormick, J., Yoder, N., Belnap, D. M., qrc243, qrc243, Morado, D. R., Briggs, J. A. G., Feschotte, C. & Shepherd, J. D., 2018, In: Cell. 172, 1-2, p. 275-288, E18 33 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The RNA exosome contributes to gene expression regulation during stem cell differentiation
Llinares, M. L., Karadoulama, Evdoxia, Chen, Y., Wojenski, L. A., Villafano, G. J., Lange, Jette Bornholdt, Andersson, Robin, Core, L., Sandelin, Albin Gustav & Jensen, T. H., 2018, In: Nucleic Acids Research. 46, 21, p. 11502-11513Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The genetic history of whaling in the Cantabrian Sea during the 13th-18th centuries: Were North Atlantic right whales (Eubalaena glacialis) the main target species?
Rey-Iglesia, A., Martinez-Cedeira, J., Lopez, A., Fernandez, R. & Campos, P., 2018, In: Journal of Archaeological Science: Reports. 18, p. 393-398 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Toroidal Diffusions and Protein Structure Evolution
Garcia Portugues, E., Golden, M., Sørensen, Michael, Mardia, K. V., Hamelryck, Thomas Wim & Hein, J., 2018, Applied Directional Statistics: Modern Methods and Case Studies. Ley, C. & Verdebout, H. (eds.). CRC Press, 34 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Transcription start site analysis reveals widespread divergent transcription in D. melanogaster and core promoter-encoded enhancer activities
Rennie, Sarah, Dalby, M., Lloret-Llinares, M., Bakoulis, Stylianos, Dalager Vaagensø, C., Jensen, T. H. & Andersson, Robin, 2018, In: Nucleic Acids Research. 46, 11, p. 5455-5469 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactions
Rennie, Sarah, Dalby, M., van Duin, Lucas & Andersson, Robin, 2018, In: Nature Communications. 9, 16 p., 487.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transfer RNA instability as a stress response in Escherichia coli: rapid dynamics of the tRNA pool as a function of demand
Sørensen, Michael Askvad, Fehler, A. O. & Svenningsen, Sine Lo, 2018, In: RNA Biology. 15, 4/5, p. 586-593 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vejledning i forskning
Brandt, Luise Ørsted, 2018Research output: Other contribution › Net publication - Internet publication › Education
- 2017
- Published
RNase H sequence preferences influence antisense oligonucleotide efficiency
Kiełpiński, Ł. J., Hagedorn, P. H., Lindow, M. & Vinther, Jeppe, 15 Dec 2017, In: Nucleic Acids Research. 45, 22, p. 12932-12944 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Founder effect of the RETC611Y mutation in multiple endocrine neoplasia 2A in Denmark: a nationwide Study
Sloth Mathiesen, J., Kroustrup, J. P., Vestergaard, P., Krag, K. S., Poulsen, P. L., Rasmussen, Å. K., Feldt-Rasmussen, Ulla, Gaustadnes, M., Ørntoft, T. F., Rossing, M., Nielsen, Finn Cilius, Albrechtsen, Anders, Brixen, K., Godballe, C. & Frederiksen, A. L., Dec 2017, In: Thyroid. 27, 12, p. 1505-1510 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An introduction to deep learning on biological sequence data: examples and solutions
Jurtz, V. I., Johansen, A. R., Nielsen, M., Almagro Armenteros, J. J., Nielsen, H., Sønderby, C. K., Winther, Ole & Sønderby, S. K., 15 Nov 2017, In: Bioinformatics. 33, 22, p. 3685-3690 6 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Heat-shock protein 40 is the key farnesylation target in meristem size control, abscisic acid signaling, and drought resistance
Barghetti, A., Sjögren, L. L. E., Floris, M. H. J., Botterweg Paredes, E., Wenkel, Stephan & Brodersen, Peter, 15 Nov 2017, In: Genes & Development. 31, 22, p. 2282-2295 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancient genomes show social and reproductive behavior of early Upper Paleolithic foragers
Sikora, M., Seguin-Orlando, A., Sousa, V. C., Albrechtsen, A., Korneliussen, T. S., Ko, A., Rasmussen, S., Dupanloup, I., Nigst, P. R., Bosch, M. D., Renaud, G., Allentoft, M. E., Margaryan, A., Vasilyev, S. V., Veselovskaya, E. V., Borutskaya, S. B., Deviese, T., Comeskey, D., Higham, T., Manica, A. & 7 others, , 3 Nov 2017, In: Science. 358, 6363, p. 659-662 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sugar metabolism of the first thermophilic Planctomycete Thermogutta terrifontis: comparative genomic and transcriptomic approaches
Elcheninov, A. G., Menzel, P., Gudbergsdottir, S. R., Slesarev, A. I., Kadnikov, V. V., Krogh, Anders, Bonch-Osmolovskaya, E. A., Peng, Xu & Kublanov, I. V., 2 Nov 2017, In: Frontiers in Microbiology. 8, 11 p., 2140.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DeepLoc: prediction of protein subcellular localization using deep learning
Almagro Armenteros, J. J., Sønderby, C. K., Sønderby, S. K., Nielsen, H. & Winther, Ole, 1 Nov 2017, In: Bioinformatics. 33, 21, p. 3387-3395 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
fastNGSadmix: admixture proportions and principal component analysis of a single NGS sample
Jørsboe, E., Hanghøj, Kristian Ebbesen & Albrechtsen, Anders, 1 Oct 2017, In: Bioinformatics. 33, 19, p. 3148-3150 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Climate change and human colonization triggered habitat loss and fragmentation in Madagascar
Salmona, J., Heller, Rasmus, Quéméré, E. & Chikhi, L., Oct 2017, In: Molecular Ecology. 26, 19, p. 5203-5222 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
De novo pathway-based biomarker identification
Alcaraz, N., List, M., Batra, R., Vandin, F., Ditzel, H. J. & Baumbach, J., 19 Sep 2017, In: Nucleic Acids Research. 45, 16, 11 p., e151.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assembly and analysis of 100 full MHC haplotypes from the Danish population
Jensen, J. M., Villesen, P., Friborg, R. M., Mailund, T., Besenbacher, S., Sørensen, L. M., Petersen, B., Sibbesen, J. A., Liu, S., Skov, L., Belling, K. G., Have, C. T., Izarzugaza, J. M. G., Grosjean, M., Bork-Jensen, J., Grove, J., Als, T. D., Huang, S., Chang, Y., Xu, R. & 39 others, , Sep 2017, In: Genome Research. 27, 9, p. 1597-1607 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The landscape of isoform switches in human cancers
Vitting-Seerup, K. & Sandelin, Albin Gustav, Sep 2017, In: Molecular Cancer Research. 15, 9, p. 1206-1220 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeted next-generation sequencing analysis identifies novel mutations in families with severe familial exudative vitreoretinopathy
Huang, X., Zhuang, H., Wu, J., Li, J., Hu, F., Zheng, Y., Tellier, L. C. A. M., Zhang, S., Gao, F., Zhang, J. & Xu, G., 23 Aug 2017, In: Molecular Vision. 23, p. 605-613 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An integrated expression atlas of miRNAs and their promoters in human and mouse
de Rie, D., Abugessaisa, I., Alam, T., Arner, E., Arner, P., Ashoor, H., Åström, G., Babina, M., Bertin, N., Burroughs, A. M., Carlisle, A. J., Daub, C. O., Detmar, M., Deviatiiarov, R., Fort, A., Gebhard, C., Goldowitz, D., Guhl, S., Ha, T. J., Harshbarger, J. & 31 others, , 21 Aug 2017, In: Nature Biotechnology. 35, 9, p. 872-878 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Generative Angular Model of Protein Structure Evolution
Golden, M., Garcia-Portugues, E., Sørensen, Michael, Mardia, K. V., Hamelryck, Thomas Wim & Hein, J., Aug 2017, In: Molecular Biology and Evolution. 34, 8, p. 2085-2100Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Applying targeted next generation sequencing to dried blood spot specimens from suspicious cases identified by tandem mass spectrometry-based newborn screening
Qian, J., Wang, X., Liu, J., Zhong, J., Le, Y., Tellier, L. C. A. M., Liu, C., Jiang, P., Gao, R. & Wang, Y., Aug 2017, In: Journal of Pediatric Endocrinology and Metabolism. 30, 9, p. 979-988 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The whole-genome landscape of medulloblastoma subtypes
Northcott, P. A., Buchhalter, I., Morrissy, A. S., Hovestadt, V., Weischenfeldt, J., Ehrenberger, T., Gröbner, S., Segura-Wang, M., Zichner, T., Rudneva, V. A., Warnatz, H. J., Sidiropoulos, N., Phillips, A. H., Schumacher, S., Kleinheinz, K., Waszak, S. M., Erkek, S., Jones, D. T. W., Worst, B. C., Kool, M. & 67 others, , 19 Jul 2017, In: Nature. 547, 7663, p. 311-317 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Eight millennia of matrilineal genetic continuity in the South Caucasus
Margaryan, Ashot, Derenko, M., Hovhannisyan, H., Malyarchuk, B., Heller, Rasmus, Khachatryan, Z., Avetisyan, P., Badalyan, R., Bobokhyan, A., Melikyan, V., Sargsyan, G., Piliposyan, A., Simonyan, H., Mkrtchyan, R., Denisova, G., Yepiskoposyan, L., Willerslev, Eske & Allentoft, Morten Erik, 10 Jul 2017, In: Current Biology. 27, 13, p. 2023-2028 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancient genomic changes associated with domestication of the horse
Sanz, P. L., Gamba, C., Gaunitz, C., Der Sarkissian, C., Pruvost, M., Albrechtsen, A., Fages, A. A., Khan, N., Schubert, M., Jagannathan, V., Serres-Armero, A., Kuderna, L. F. K., Povolotskaya, I. S., Seguin-Orlando, A., Lepetz, S., Neuditschko, M., Thèves, C., Alquraishi, S., Alfarhan, A. H., AL-Rasheid, K. & 13 others, , 28 Apr 2017, In: Science. 356, 6336, p. 442-445 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptional changes induced by bevacizumab combination therapy in responding and non-responding recurrent glioblastoma patients
Urup, T., Staunstrup, L. M., Michaelsen, Signe Regner, Vitting-Seerup, K., Bennedbæk, M., Toft, A., Olsen, L. R., Jønson, L., Issazadeh-Navikas, Shohreh, Broholm, H., Hamerlik, P., Poulsen, H. S. & Lassen, Ulrik Niels, 18 Apr 2017, In: BMC Cancer. 17, 10 p., 278.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chirality in microbial biofilms is mediated by close interactions between the cell surface and the substratum
Jauffred, Liselotte, Vejborg, R. M., Korolev, K. S., Brown, Stanley & Oddershede, L. B., 14 Apr 2017, In: I S M E Journal. 11, 7, p. 1688-1701Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Highly accessible AU-rich regions in 3' untranslated regions are hotspots for binding of regulatory factors
Plass, M., Rasmussen, S. H. & Krogh, Anders, 14 Apr 2017, In: PLoS Computational Biology. 13, 4, 26 p., e1005460.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas
Mohammad, F., Weissmann, S., Leblanc, B. O., Pandey, D. P., Højfeldt, J. W., Comet, I., Zheng, C., Johansen, Jens Vilstrup, Rapin, N. P. J., Porse, Bo Torben, Tvardovskiy, A., Jensen, O. N., Olaciregui, N. G., Lavarino, C., Suñol, M., de Torres, C., Mora, J., Carcaboso, A. M. & Helin, K., Apr 2017, In: Nature Medicine. 23, 4, p. 483-492 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sphingosine-1-phosphate signaling in inflammatory bowel disease
Nielsen, Ole Haagen, Li, Yuan, Lindbom, B. J. & Coskun, M., Apr 2017, In: Trends in Molecular Medicine. 23, 4, p. 362-374 13 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Molecular clocks indicate turnover and diversification of modern coleoid cephalopods during the Mesozoic Marine Revolution
Tanner, A. R., Fuchs, D., Winkelmann, I. E. H., Gilbert, M Thomas P, Pankey, M. S., Oliveira Ribeiro, Â. M., Kocot, K. M., Halanych, K. M., Oakley, T. H., Rodrigues da Fonseca, Rute Andreia, Pisani, D. & Vinther, J., 15 Mar 2017, In: Proceedings of the Royal Society B: Biological Sciences. 284, 1850, 7 p., 20162818.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extinctions, genetic erosion and conservation options for the black rhinoceros (Diceros bicornis)
Moodley, Y., Russo, I. M., Dalton, D. L., Kotzé, A., Muya, S., Haubensak, P., Bálint, B., Munimanda, G. K., Deimel, C., Setzer, A., Dicks, K., Herzig-Straschil, B., Kalthoff, D. C., Siegismund, Hans Redlef, Robovský, J., O'Donoghue, P. & Bruford, M. W., 8 Feb 2017, In: Scientific Reports. 7, 16 p., 41417.Research output: Contribution to journal › Journal article › Research › peer-review
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Reconstructing genome evolution in historic samples of the Irish potato famine pathogen
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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True single-molecule DNA sequencing of a pleistocene horse bone
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