- 2014
- Published
Genome-wide analysis of noncoding regulatory mutations in cancer
Weinhold, N., Skanderup, A. M. J., Schultz, N., Sander, C. & Lee, W., 2014, In: Nature Genetics. 46, 11, p. 1160-1165 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide nucleosome map and cytosine methylation levels of an ancient human genome
Pedersen, J. S., Valen, E., Velazquez, A. M. V., Parker, B. J., Rasmussen, M., Lindgreen, S., Lilje, B., Tobin, D. J., Kelly, T. K., Vang, S., Andersson, R., Jones, P. A., Hoover, C. A., Tikhonov, A., Prokhortchouk, E., Rubin, E. M., Sandelin, A. G., Gilbert, M. T. P., Krogh, A., Willerslev, E. & 1 others, , 2014, In: Genome Research. 24, 3, p. 454-466 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic structure in Europeans dating back at least 36,200 years
Seguin-Orlando, A., Korneliussen, T. S., Sikora, M., Malaspinas, A. S., Manica, A., Moltke, I., Albrechtsen, A., Ko, A., Margaryan, A., Moiseyev, V., Goebel, T., Westaway, M., Lambert, D., Khartanovich, V., Wall, J. D., Nigst, P. R., Foley, R. A., Lahr, M. M., Nielsen, R., Orlando, L. A. A. & 1 others, , 2014, In: Science. 346, 6213, p. 1113-1118 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-Throughput Sequencing Based Methods of RNA Structure Investigation
Kielpinski, L. J., 2014, Department of Biology, Faculty of Science, University of Copenhagen. 137 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Human nonsense-mediated RNA decay initiates widely by endonucleolysis and targets snoRNA host genes
Lykke-Andersen, S., Chen, Y., Ardal, B., Lilje, B., Waage, J. E., Sandelin, Albin Gustav & Jensen, T. H., 2014, In: Genes & Development. 28, p. 2498-2517 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IMP3 RNP safe houses prevent miRNA-directed HMGA2 mRNA decay in cancer and development
Jønson, L., Christiansen, Jan, Hansen, Thomas van Overeem, Vikeså, J., Yamamoto, Y. & Nielsen, Finn Cilius, 2014, In: Cell Reports. 7, 2, p. 539-551 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2
Boyd, M., Coskun, M., Lilje, B., Andersson, Robin, Hoof, I., Lange, Jette Bornholdt, Dahlgaard, K., Olsen, Jørgen, Vitezic, M., Bjerrum, Jakob Tveiten , Seidelin, Jakob Benedict, Nielsen, Ole Haagen, Troelsen, J. & Sandelin, Albin Gustav, 2014, In: D N A Research. 21, 6, p. 569-583 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrating genetic data and population viability analyses for the identification of harbour seal (Phoca vitulina) populations and management units
Olsen, Morten Tange, Andersen, L. W., Dietz, R., Teilmann, J., Härkönen, T. & Siegismund, Hans Redlef, 2014, In: Molecular Ecology. 23, 4, p. 815-831 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Involvement of CDX2 in the cross talk between TNF-α and Wnt signaling pathway in the colon cancer cell line Caco-2
Coskun, M., Olsen, A. K., Bzorek, M., Holck, S., Engel, U. H., Nielsen, Ole Haagen & Troelsen, J. T., 2014, In: Carcinogenesis. 35, 5, p. 1185-1192 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is diagnosability an indicator of speciation? Response to "Why one century of phenetics is enough"
Heller, Rasmus, Frandsen, P., Lorenzen, Eline & Siegismund, Hans Redlef, 2014, In: Systematic Biology. 63, 5, p. 833-837 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles
Mathelier, A., Zhao, X., Zhang, A. W., Parcy, F., Worsley-Hunt, R., Arenillas, D. J., Buchman, S., Chen, C., Chou, A., Ienasescu, H., Lim, J., Shyr, C., Tan, G., Zhou, M., Lenhard, B., Sandelin, Albin Gustav & Wasserman, W. W., 2014, In: Nucleic Acids Research. 42, p. D142-D147 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Massive parallel-sequencing-based hydroxyl radical probing of RNA accessibility
Kielpinski, L. J. & Vinther, Jeppe, 2014, In: Nucleic Acids Research. 42, 8, 12 p., e70.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MicroRNA expression analysis and Multiplex ligation-dependent probe amplification in metastatic and non-metastatic uveal melanoma
Larsen, A., Holst, L. M., Kaczkowski, B., Andersen, M. T., Manfé, V., Siersma, Volkert Dirk, Kolko, Miriam, Kiilgaard, Jens Folke, Winther, Ole, Prause, J. U., Gniadecki, R. & Heegaard, Steffen, 2014, In: Acta Ophthalmologica. 92, 6, p. 541-549Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modification of T cell responses by stem cell mobilization requires direct signaling of the T cell by G-CSF and IL-10
MacDonald, K. P. A., Le Texier, L., Zhang, P., Morris, H., Kuns, R. D., Lineburg, K. E., Leveque, L., Don, A. L., Markey, K. A., Vuckovic, S., Bagger, F. O., Boyle, G. M., Blazar, B. R. & Hill, G. R., 2014, In: Journal of Immunology. 192, 7, p. 3180-3189 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular architecture of transcription factor hotspots in early adipogenesis
Siersbæk, R., Baek, S., Rabiee, A., Nielsen, R., Traynor, S., Clarke, N., Sandelin, Albin Gustav, Jensen, O. N., Sung, M., Hager, G. L. & Mandrup, S., 2014, In: Cell Reports. 7, 5, p. 1434-1442 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nuclear stability and transcriptional directionality separate functionally distinct RNA species
Andersson, Robin, Refsing Andersen, P., Valen, E., Core, L. J., Lange, Jette Bornholdt, Boyd, M., Jensen, T. H. & Sandelin, Albin Gustav, 2014, In: Nature Communications. 5, 10 p., 5336.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On detecting incomplete soft or hard selective sweeps using haplotype structure
Ferrer-Admetlla, A., Liang, M., Korneliussen, Thorfinn Sand & Nielsen, Rasmus, 2014, In: Molecular Biology and Evolution. 31, 5, p. 1275-1291 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oncogenic fusion proteins expressed in immature hematopoietic cells fail to recapitulate the transcriptional changes observed in human AML
Rapin, N. & Porse, Bo Torben, 2014, In: Oncogenesis. 3, p. 1-5 5 p., e106.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Pharmaco-miR: linking microRNAs and drug effects
Rukov, J. L., Wilentzik, R., Jaffe, I., Vinther, Jeppe & Shomron, N., 2014, In: Briefings in Bioinformatics. 15, 4, p. 648-659 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Population genomics reveal recent speciation and rapid evolutionary adaptation in polar bears
Liu, S., Lorenzen, E., Fumagalli, M., Li, B., Harris, K., Xiong, Z., Zhou, L., Korneliussen, T. S., Somel, M., Babbitt, C., Wray, G., Li, J., He, W., Wang, Z., Fu, W., Xiang, X., Morgan, C. C., Doherty, A., O'Connell, M. J., McInerney, J. O. & 9 others, , 2014, In: Cell. 157, 4, p. 785-794 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prehistoric genomes reveal the genetic foundation and cost of horse domestication
Schubert, M., Jónsson, H., Chang, D., Der Sarkissian, C., Ermini, L., Ginolhac, A., Albrechtsen, A., Dupanloup, I., Foucal, A., Petersen, B., Fumagalli, M., Raghavan, M., Seguin-Orlando, A., Korneliussen, T. S., Velazquez, A. M. V., Stenderup, J., Hoover, C. A., Rubin, C-J., Alfarhan, A. H., Alquraishi, S. A. & 15 others, , 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 52, p. E5661–E5669 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Probabilistic determination of native state ensembles of proteins
Olsson, S., Vögeli, B. R., Cavalli, A., Boomsma, Wouter, Ferkinghoff-Borg, J., Lindorff-Larsen, Kresten & Hamelryck, Thomas Wim, 2014, In: Journal of Chemical Theory and Computation. 10, 8, p. 3484-3491 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RECLU: a pipeline to discover reproducible transcriptional start sites and their alternative regulation using capped analysis of gene expression (CAGE)
Ohmiya, H., Vitezic, M., Frith, M. C., Itoh, M., Carninci, P., Forrest, A. R. R., Hayashizaki, Y., Lassmann, T. & The FANTOM Consortium, T. F. C., 2014, In: B M C Genomics. 15, 15 p., 269.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rapid detection of structural variation in a human genome using nanochannel-based genome mapping technology
Cao, H., Hastie, A. R., Cao, D., Lam, E. T., Sun, Y., Huang, H., Liu, X., Lin, L., Andrews, W., Chan, S., Huang, S., Tong, X., Requa, M., Anantharaman, T., Krogh, Anders, Yang, H., Cao, H. & Xu, X., 2014, In: GigaScience. 3, 11 p., 34.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RelateAdmix: a software tool for estimating relatedness between admixed individuals
Moltke, Ida & Albrechtsen, Anders, 2014, In: Bioinformatics. 30, 7, p. 1027-1028 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Robust identification of noncoding RNA from transcriptomes requires phylogenetically-informed sampling
Lindgreen, S., Umu, S. U., Lai, A. S., Eldai, H., Liu, W., McGimpsey, S., Wheeler, N. E., Biggs, P. J., Thomson, N. R., Barquist, L., Poole, A. M. & Gardner, P. P., 2014, In: P L o S One. 10, 10, 10 p., e1003907.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SNPest: a probabilistic graphical model for estimating genotypes
Lindgreen, S., Krogh, Anders & Pedersen, J. S., 2014, In: BMC Research Notes. 7, 12 p., 298.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Speciation with gene flow in equids despite extensive chromosomal plasticity
Jónsson, H., Schubert, M., Seguin-Orlando, A., Ginolhac, A., Petersen, L., Fumagalli, M., Albrechtsen, A., Petersen, B., Korneliussen, T. S., Mouatt, J. T. V., Lear, T., Myka, J. L., Lundquist, J., Miller, D. C., Alfarhan, A. H., Alquraishi, S. A., Al-Rasheid, K. A. S., Stagegaard, J., Strauss, G., Bertelsen, M. F. & 6 others, , 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 52, p. 18655–18660 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy
Bruedigam, C., Bagger, F. O., Heidel, F. H., Kuhn, C. P., Guignes, S., Song, A., Austin, R., Vu, T., Lee, E., Riyat, S., Moore, A. S., Lock, R. B., Bullinger, L., Hill, G. R., Armstrong, S. A., Williams, D. A. & Lane, S. W., 2014, In: Cell Stem Cell. 15, 6, p. 775-790 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The genetic prehistory of the New World Arctic
Raghavan, M., DeGiorgio, M., Albrechtsen, A., Moltke, I., Skoglund, P., Korneliussen, T. S., Grønnow, B., Appelt, M., Gulløv, H. C., Friesen, T. M., Fitzhugh, W., Malmström, H. S., Rasmussen, S., Olsen, J., Melchior, L. C., Fuller, B. T., Fahrni, S. M., Stafford jr., T., Grimes, V., Renouf, M. A. P. & 36 others, , 2014, In: Science. 345, 6200, 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The genome of a Late Pleistocene human from a Clovis burial site in western Montana
Rasmussen, M., Anzick, S. L., Waters, M. R., Skoglund, P., DeGiorgio, M., Stafford jr., T., Rasmussen, S., Moltke, I., Albrechtsen, A., Doyle, S. M., Poznik, G. D., Gudmundsdottir, V., Yadav, R., Malaspinas, A. S., White, S. S., Allentoft, M. E., Cornejo, O. E., Tambets, K., Eriksson, A., Heintzman, P. D. & 22 others, , 2014, In: Nature. 506, 7487, p. 225-229 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Toward Larger DNA Origami
Marchi, A. N., Saaem, I., Vogen, B. N., Brown, Stanley & LaBean, T. H., 2014, In: Nano Letters. 14, 10, p. 5740-5747 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptional profiling of the human fibrillin/LTBP gene family, key regulators of mesenchymal cell functions
Davis, M. R., Andersson, Robin, Severin, J., de Hoon, M., Bertin, N., Baillie, J. K., Kawaji, H., Sandelin, Albin Gustav, Forrest, A. R. R. & Summers, K. M., 2014, In: Molecular Genetics and Metabolism. 112, 3, p. 73-83 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tumor antigens as proteogenomic biomarkers in invasive ductal carcinomas
Olsen, L. R., Campos, B., Winther, Ole, Sgroi, D. C., Karger, B. L. & Brusic, V., 2014, In: B M C Medical Genomics. 7, 3, p. 1-13 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two ancient human genomes reveal Polynesian ancestry among the indigenous Botocudos of Brazil
Malaspinas, A. S., Lao, O., Schroeder, H., Rasmussen, M., Raghavan, M., Moltke, I., Campos, P., Sagredo, F. S., Rasmussen, S., Gonçalves, V. F., Albrechtsen, A., Allentoft, M. E., Johnson, P. L. F., Li, M., Reis, S., Bernardo, D. V., DeGiorgio, M., Duggan, A. T., Bastos, M., Wang, Y. & 20 others, , 2014, In: Current biology : CB. 24, 21, p. R1035-R1037 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Upper palaeolithic Siberian genome reveals dual ancestry of Native Americans
Raghavan, M., Skoglund, P., Graf, K. E., Metspalu, M., Albrechtsen, A., Moltke, I., Rasmussen, S., Stafford jr., T., Orlando, L. A. A., Metspalu, E., Karmin, M., Tambets, K., Rootsi, S., Mägi, R., Campos, P., Balanovska, E., Balanovsky, O., Khusnutdinova, E., Litvinov, S., Osipova, L. P. & 11 others, , 2014, In: Nature. 505, 7481, p. 87-91 4 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Variation and association to diabetes in 2000 full mtDNA sequences mined from an exome study in a Danish population
Li, S., Besenbacher, S., Li, Y., Kristiansen, Karsten, Grarup, Niels, Albrechtsen, Anders, Sparsø, T. H., Korneliussen, Thorfinn Sand, Hansen, Torben, Wang, J., Nielsen, Rasmus, Pedersen, Oluf Borbye, Bolund, L. & Schierup, M. H., 2014, In: European Journal of Human Genetics. 22, p. 1040-1045 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole-genome sequencing of cultivated and wild peppers provides insights into Capsicum domestication and specialization
Qin, C., Yu, C., Shen, Y., Fang, X., Chen, L., Min, J., Cheng, J., Zhao, S., Xu, M., Luo, Y., Yang, Y., Wu, Z., Mao, L., Wu, H., Ling-Hu, C., Zhou, H., Lin, H., Gonzalez-Morales, S., Trejo-Saavedra, D. L., Tian, H. & 53 others, , 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 14, p. 5135-5140 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
spliceR: an R package for classification of alternative splicing and prediction of coding potential from RNA-seq data
Vitting-Seerup, K., Porse, Bo Torben, Sandelin, Albin Gustav & Waage, J., 2014, In: B M C Bioinformatics. 15, p. 1-7 7 p., 81.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes
Lohmueller, K. E., Sparsø, T. H., Li, Q., Galijatovic, E. A. A., Korneliussen, T. S., Albrechtsen, A., Banasik, K., Grarup, N., Hallgrimsdottir, I., Kiil, K., Oskari Kilpeläinen, T., Krarup, N. T., Pers, T. H., Sanchez, G., Hu, Y., DeGiorgio, M., Jørgensen, T., Sandbæk, A., Lauritzen, T., Brunak, S. & 6 others, , 5 Dec 2013, In: American Journal of Human Genetics. 93, 6, p. 1072-1086 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bacterial natural transformation by highly fragmented and damaged DNA
Overballe-Petersen, S., Harms, K., Orlando, L. A. A., Moreno Mayar, J. Víctor, Rasmussen, Simon, Dahl, Tais Wittchen, Rosing, Minik Thorleif, Poole, A. M., Sicheritz-Ponten, T., Brunak, S., Inselmann, S., de Vries, J., Wackernagel, W., Pybus, O. G., Nielsen, Rasmus, Johnsen, P. J., Nielsen, K. M. & Willerslev, Eske, 3 Dec 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 49, p. 19860–19865 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimating individual admixture proportions from next generation sequencing data
Skotte, L., Korneliussen, Thorfinn Sand & Albrechtsen, Anders, Nov 2013, In: Genetics. 195, 3, p. 693-702 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantifying population genetic differentiation from next-generation sequencing data
Fumagalli, M., Vieira, Filipe Garrett, Korneliussen, Thorfinn Sand, Linderoth, T., Huerta-Sánchez, E., Albrechtsen, Anders & Nielsen, Rasmus, Nov 2013, In: Genetics. 195, 3, p. 979-992 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA supercoiling enhances cooperativity and efficiency of an epigenetic switch
Norregaard, K., Andersson, M., Sneppen, Kim, Nielsen, Peter E., Brown, Stanley & Oddershede, L. B., 22 Oct 2013, In: Proceedings of the National Academy of Sciences USA (PNAS). 110, 43, p. 17386-91 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lack of the p42 form of C/EBPα leads to spontaneous immortalization and lineage infidelity of committed myeloid progenitors
Schuster, Mikkel Bruhn, Frank, Anne-Katrine, Bagger, F. O., Rapin, N., Vikesaa, J. & Porse, Bo Torben, Oct 2013, In: Experimental Hematology. 41, 10, p. 882-893 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MiR-492 impairs the angiogenic potential of endothelial cells
Patella, F., Leucci, E., Evangelista, M., Parker, B., Wen, J., Mercatanti, A., Rizzo, M., Chiavacci, E., Lund, Anders H. & Rainaldi, G., Aug 2013, In: Journal of Cellular and Molecular Medicine. 17, 8, p. 1006-15 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reconstructing genome evolution in historic samples of the Irish potato famine pathogen
Martin, M. D., Cappellini, Enrico, Samaniego Castruita, J. A., Zepeda Mendoza, M. L., Campos, P., Seguin-Orlando, A., Wales, N., Orlando, L. A. A., Ho, S. Y. W., Dietrich, F. S., Mieczkowski, P. A., Heitman, J., Willerslev, Eske, Krogh, Anders, Ristaino, J. B. & Gilbert, M Thomas P, 18 Jul 2013, In: Nature Communications. 4, 7 p., 2172.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse
Orlando, L. A. A., Ginolhac, A., Zhang, G., Froese, D., Albrechtsen, A., Stiller, M., Schubert, M., Cappellini, E., Petersen, B., Moltke, I., Johnson, P. L. F., Fumagalli, M., Mouatt, J. T. V., Raghavan, M., Korneliussen, T. S., Malaspinas, A. S., Vogt, J., Szklarczyk, D. M., Kelstrup, C., Vinther, J. & 36 others, , 4 Jul 2013, In: Nature. 499, 7456, p. 74-78 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Hepatocyte growth factor activator inhibitor-2 prevents shedding of matriptase
Larsen, B. R., Steffensen, S. D. R., Nielsen, N. V. L., Friis, S., Godiksen, S., Lange, Jette Bornholdt, Soendergaard, C., Nonboe, Annika Weile, Andersen, M. N., Poulsen, Steen Seier, Szabo, R., Bugge, T. H., Lin, C., Skovbjerg, H., Jensen, J. K. & Vogel, Lotte, 1 Apr 2013, In: Experimental Cell Research. 319, 6, p. 918-929 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Temporal mapping of CEBPA and CEBPB binding during liver regeneration reveals dynamic occupancy and specific regulatory codes for homeostatic and cell cycle gene batteries
Jakobsen, J. S., Waage, J., Rapin, N., Bisgaard, Hanne Cathrine, Larsen, F. S. & Porse, Bo Torben, Apr 2013, In: Genome Research. 23, 4, p. 592-603 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fbxl10/Kdm2b recruits polycomb repressive complex 1 to CpG islands and regulates H2A ubiquitylation
Wu, X., Johansen, Jens Vilstrup & Helin, K., 28 Mar 2013, In: Molecular Cell. 49, 6, p. 1134-46 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Are there really twice as many bovid species as we thought?
Heller, Rasmus, Frandsen, P., Lorenzen, Eline & Siegismund, Hans Redlef, Mar 2013, In: Systematic Biology. 62, 3, p. 490-493 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SigniSite: identification of residue-level genotype-phenotype correlations in protein multiple sequence alignments
Jessen, L. E., Hoof, I., Lund, O. & Nielsen, M., 2013, In: Nucleic Acids Research. 41, W1, p. W286-W291 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A short-read multiplex sequencing method for reliable, cost-effective and high-throughput genotyping in large-scale studies: [plus] Erratum
Cao, H., Wang, Y., Zhang, W., Chai, X., Zhang, X., Chen, S., Yang, F., Zhang, C., Guo, Y., Liu, Y., Tang, Z., Chen, C., Xue, Y., Zhen, H., Xu, Y., Rao, B., Liu, T., Zhao, M., Zhang, W., Li, Y. & 6 others, , 2013, In: Human Mutation. 34, 12, p. 1715-1720 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A simple probabilistic model of multibody interactions in proteins
Johansson, Kristoffer Enøe & Hamelryck, Thomas Wim, 2013, In: Proteins: Structure, Function, and Bioinformatics. 81, 8, p. 1340-1350 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A study of bacterial gene regulatory mechanisms: Dynamic features of gene regulatory mechanisms in EscherichEia coli and small RNA post-transcriptional regulation in Vibrio cholerae
Hansen, S., 2013, Department of Biology, Faculty of Science, University of Copenhagen. 134 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Acute Genome-wide effects of Rosiglitazone on PPARγ transcriptional networks in Adipocytes
Haakonsson, A. K., Madsen, M. S., Nielsen, R., Sandelin, Albin Gustav & Mandrup, S., 2013, In: Molecular Endocrinology. 27, 9, p. 1536-1549 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Alterations in polyadenylation and its implications for endocrine disease
Rehfeld, Anders Aagaard, Plass, M., Krogh, Anders & Friis-Hansen, Lennart Jan, 2013, In: Frontiers in Endocrinology. 4, 23 p., 53.Research output: Contribution to journal › Review › Research › peer-review
- Published
BlockLogo: visualization of peptide and sequence motif conservation
Olsen, L. R., Kudahl, U. J., Simon, C., Sun, J., Schönbach, C., Reinherz, E. L., Zhang, G. L. & Brusic, V., 2013, In: Journal of Immunological Methods. 400-401, p. 37-44 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Body fluid identification of blood, saliva and semen using second generation sequencing of micro-RNA
Petersen, C. H., Hjort, B. B., Tvedebrink, T., Kielpinski, L. J., Vinther, Jeppe & Morling, Niels, 2013, In: Forensic Science International: Genetics Supplement Series. 4, 1, p. e204-5 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bringing genetic diversity to the forefront of conservation policy and management
Hoban, S. M., Hauffe, H. C., Pérez-Espona, S., Arntzen, J. W., Bertorelle, G., Bryja, J., Frith, K., Gaggiotti, O. E., Galbusera, P., Godoy, J. A., Hoelzel, A. R., Nichols, R. A., Primmer, C. R., Russo, I., Segelbacher, G., Siegismund, Hans Redlef, Sihvonen, M., Vernesi, C., Vilà, C. & Bruford, M. W., 2013, In: Conservation Genetics Resources. 5, 2, p. 593-598 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Calculation of Tajima's D and other neutrality test statistics from low depth next-generation sequencing data
Korneliussen, Thorfinn Sand, Moltke, Ida, Albrechtsen, Anders & Nielsen, Rasmus, 2013, In: B M C Bioinformatics. 14, 14 p., 289.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combining the multicanonical ensemble with generative probabilistic models of local biomolecular structure
Frellsen, J., Hamelryck, Thomas Wim & Ferkinghoff-Borg, J., 2013, Proceedings of the 59th World Statistics Congress of the International Statistical Institute, 2013 . Hague, p. 139-144 6 p.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research
- Published
Conservation genetic resources for effective species survival (ConGRESS): bridging the divide between conservation research and practice
Hoban, S., Arntzen, J. W., Bertorelle, G., Bryja, J., Fernandes, M., Frith, K., Gaggiotti, O., Galbusera, P., Godoy, J. A., Hauffe, H. C., Hoelzel, A. R., Nichols, R. A., Perez-Espona, S., Primmer, C., Russo, I-R. M., Segelbacher, G., Siegismund, H. R., Sihvonen, M., Sjogren-Gulve, P., Vernesi, C. & 2 others, , 2013, In: Journal for Nature Conservation. 21, 6, p. 433-437 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection of Active Matriptase using a Biotinylated Chloromethyl Ketone Peptide
Godiksen, S., Soendergaard, C., Friis, S., Jensen, J. K., Lange, Jette Bornholdt, Sales, K. U., Huang, M., Bugge, T. H. & Vogel, Lotte, 2013, In: P L o S One. 8, 10, 10 p., e77146.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection of reverse transcriptase termination sites using cDNA ligation and massive parallel sequencing
Kielpinski, L. J., Boyd, M., Sandelin, Albin Gustav & Vinther, Jeppe, 2013, In: Methods in molecular biology (Clifton, N.J.). 1038, p. 213-31 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Drosha regulates gene expression independently of RNA cleavage function
Gromak, N., Dienstbier, M., Macias, S., Plass, M., Eyras, E., Cáceres, J. F. & Proudfoot, N. J., 2013, In: Cell Reports. 5, 6, p. 1499-510 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enterococcus faecalis infection causes inflammation, intracellular oxphos-independent ROS production, and DNA damage in human gastric cancer cells
Strickertsson, J. A. B., Desler, Claus, Martin-Bertelsen, T., Machado, A. M. D., Wadstrøm, T., Winther, Ole, Rasmussen, Lene Juel & Friis-Hansen, Lennart Jan, 2013, In: PLOS ONE. 8, 4, p. 1-13 13 p., e63147.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimating inbreeding coefficients from NGS data: impact on genotype calling and allele frequency estimation
Vieira, Filipe Garrett, Fumagalli, M., Albrechtsen, Anders & Nielsen, Rasmus, 2013, In: Genome Research. 23, p. 1852-1861 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes
Albrechtsen, A., Grarup, N., Li, Y., Sparsø, T. H., Tian, G., Cao, H., Jiang, T., Kim, S. Y., Korneliussen, T. S., Li, Q., Nie, C., Wu, R., Skotte, L., Morris, A. P., Ladenvall, C., Cauchi, S., Stancáková, A., Andersen, G., Astrup, A., Banasik, K. & 86 others, , 2013, In: Diabetologia. 56, 2, p. 298-310 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
Grarup, N., Sulem, P., Sandholt, C. H., Thorleifsson, G., Ahluwalia, T. V. S., Steinthorsdottir, V., Bjarnason, H., Gudbjartsson, D. F., Magnusson, O. T., Sparsø, T., Albrechtsen, A., Kong, A., Masson, G., Tian, G., Cao, H., Nie, C., Kristiansen, K., Husemoen, L. L., Thuesen, B., Li, Y. & 10 others, , 2013, In: P L o S Genetics. 9, 6, 12 p., e1003530.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic signatures reveal high-altitude adaptation in a set of Ethiopian populations
Huerta-Sánchez, E., DeGiorgio, M., Pagani, L., Tarekegn, A., Ekong, R., Antao, T., Cardona, A., Montgomery, H. E., Cavalleri, G. L., Robbins, P. A., Weale, M. E., Bradman, N., Bekele, E., Kivisild, T., Tyler-Smith, C. & Nielsen, Rasmus, 2013, In: Molecular Biology and Evolution. 30, 8, p. 1877-1888 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome analysis reveals insights into physiology and longevity of the Brandt's bat Myotis brandtii
Seim, I., Fang, X., Xiong, Z., Lobanov, A. V., Huang, Z., Ma, S., Feng, Y., Turanov, A. A., Zhu, Y., Lenz, T. L., Gerashchenko, M. V., Fan, D., Yim, S. H., Yao, X., Jordan, D., Xiong, Y., Ma, Y., Lyapunov, A. N., Chen, G., Kulakova, O. I. & 9 others, , 2013, In: Nature Communications. 4, 8 p., 2212.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study of genetic variants in LPS-stimulated IL-6, IL-8, IL-10, IL-1ra and TNF-α cytokine response in a Danish Cohort
Larsen, M. H., Albrechtsen, Anders, Thørner, L. W., Werge, T., Hansen, T., Gether, Ulrik, Haastrup, E. & Ullum, H., 2013, In: PLOS ONE. 8, 6, 6 p., e66262.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Great ape genetic diversity and population history
Prado-Martinez, J., Sudmant, P. H., Kidd, J. M., Li, H., Kelley, J. L., Lorente-Galdos, B., Veeramah, K. R., Woerner, A. E., O'Connor, T. D., Santpere, G., Cagan, A., Theunert, C., Casals, F., Laayouni, H., Munch, K., Hobolth, A., Halager, A. E., Malig, M., Hernandez-Rodriguez, J., Hernando-Herraez, I. & 55 others, , 2013, In: Nature. 499, 7459, p. 471-475 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis
Bagger, F. O., Rapin, N. P. J., Theilgaard-Mønch, Kim, Kaczkowski, B., Thorén, L. A. M., Jendholm, L. J., Winther, Ole & Porse, Bo Torben, 2013, In: Nucleic Acids Research. 41, Database issue, p. D1034-D1039 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improving The Analysis Of Gene Expression Profiles By Comparing AML Blasts With Their Nearest Normal Counterparts
Rapin, N., Bagger, F. O., Jendholm, J., Mora-Jensen, H. I., Krogh, Anders, Kohlmann, A., Thiede, C., Borregaard, N., Bullinger, L., Winther, Ole, Theilgaard-Mønch, Kim & Porse, Bo Torben, 2013, In: Blood. 122, 21Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Inference of structure ensembles of flexible biomolecules from sparse, averaged data
Olsson, S., Frellsen, J., Boomsma, Wouter, Mardia, K. V. & Hamelryck, Thomas Wim, 2013, In: PLoS ONE. 8, 11, 7 p., e79439.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inference problems in structural biology: protein structures and protein structure ensembles
Olsson, S., 2013, Department of Biology, Faculty of Science, University of Copenhagen. 138 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Inferring demographic history from a spectrum of shared haplotype lengths
Harris, K. & Nielsen, Rasmus, 2013, In: P L o S Genetics. 9, 6, 20 p., e1003521.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Laboratory capacity for diagnosis of foot-and-mouth disease in Eastern Africa: implications for the progressive control pathway
Namatovu, A., Wekesa, S. N., Tjørnehøj, K., Dhikusooka, M. T., Muwanika, V. B., Siegismund, Hans Redlef & Ayebazibwe, C., 2013, In: B M C Veterinary Research. 9, 19, 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lessons on RNA silencing mechanisms in plants from Eukaryotic Argonaute structures
Poulsen, C., Vaucheret, H. & Brodersen, Peter, 2013, In: Plant Cell. 25, 1, p. 22-37 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Literature classification for semi-automated updating of biological knowledgebases
Olsen, L. R., Kudahl, U. J., Winther, Ole & Brusic, V., 2013, In: B M C Genomics. 14(Suppl 5), 10 p., S14.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss of miR-10a activates Lpo and collaborates with activated Wnt signaling in inducing intestinal Neoplasia in female mice
Stadthagen Gomez, G., Tehler, D. E., Høyland-Kroghsbo, Nina Molin, Wen, J., Krogh, Anders, Jensen, K. T., Santoni Rugiu, Eric, Engelholm, Lars Henning & Lund, Anders H., 2013, In: P L o S Genetics. 9, 10, 12 p., e1003913.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular footprints of domestication and improvement in soybean revealed by whole genome re-sequencing
Li, Y., Zhao, S., Ma, J., Li, D., Yan, L., Li, J., Qi, X., Guo, X., Zhang, L., He, W., Chang, R., Liang, Q., Guo, Y., Ye, C., Wang, X., Tao, Y., Guan, R., Wang, J., Liu, Y., Jin, L. & 15 others, , 2013, In: BMC Genomics. 14, 12 p., 579.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nanger (granti) Grant's Gazelle Species Group
Siegismund, Hans Redlef, Lorenzen, Eline & Arctander, P., 2013, Mammals of Africa: Pigs, Hippopotamuses, Chevrotain, Giraffes, Deer and Bovids. Kingdon, J. & Hoffmann, M. (eds.). London: Bloomsbury Academic, Vol. VI. p. 373–379 7 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
On the accuracy of short read mapping
Menzel, K. P., Frellsen, J., Plass, M., Rasmussen, S. H. & Krogh, Anders, 2013, Deep Sequencing Data Analysis. Shomron, N. (ed.). Springer Science+Business Media, p. 39-59 21 p. (Methods in Molecular Biology, Vol. 1038).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
PHAISTOS: a framework for Markov chain Monte Carlo simulation and inference of protein structure
Boomsma, Wouter, Frellsen, J., Harder, T. P., Bottaro, S., Johansson, Kristoffer Enøe, Tian, P., Stovgaard, K., Andreetta, C., Olsson, S., Valentin, J., Antonov, L. D., Christensen, A. S., Borg, M., Jensen, Jan Halborg, Lindorff-Larsen, Kresten, Ferkinghoff-Borg, J. & Hamelryck, Thomas Wim, 2013, In: Journal of Computational Chemistry. 34, 19, p. 1697-1705 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pan-African Genetic Structure in the African Buffalo (Syncerus caffer): Investigating Intraspecific Divergence
Smitz, N., Berthouly, C., Cornélis, D., Heller, Rasmus, Hooft, P. V., Chardonnet, P., Caron, A., Prins, H., Vuuren, B. J. V., Iongh, H. D. & Michaux, J., 2013, In: P L o S One. 8, 2, p. 1-17 17 p., e56235.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Parallel GPGPU Evaluation of Small Angle X-ray Scattering Profiles in a Markov Chain Monte Carlo Framework
Antonov, L. D., Andreetta, C. & Hamelryck, Thomas Wim, 2013, Biomedical Engineering Systems and Technologies. Gabriel, J., Schier, J. & Huffel, S. V. (eds.). Springer Science+Business Media, Vol. 357. p. 222-235 14 p. (Communications in Computer and Information Science).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Phaistos user manual
Boomsma, Wouter, Bottaro, S., Hamelryck, Thomas Wim, Frellsen, J., Andreetta, C., Borg, M., Harder, T., Johansson, Kristoffer Enøe, Stovgaard, K. & Tian, P., 2013, 90 p.Research output: Book/Report › Book › Education
- Published
Polyadenylation site-induced decay of upstream transcripts enforces promoter directionality
Ntini, E., Järvelin, A. I., Lange, Jette Bornholdt, Chen, Y., Boyd, M., Jørgensen, M., Andersson, Robin, Hoof, I., Schein, A., Andersen, P. R., Andersen, P. K., Preker, P., Valen, E., Zhao, X., Pelechano, V., Steinmetz, L. M., Sandelin, Albin Gustav & Jensen, T. H., 2013, In: Nature Structural and Molecular Biology. 20, p. 923-928 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Probabilistic Equilibrium Sampling of Protein Structures from SAXS Data and a Coarse Grained Debye Formula
Andreetta, C., 2013, Department of Biology, Faculty of Science, University of Copenhagen.Research output: Book/Report › Ph.D. thesis › Research
- Published
Protein structure validation and refinement using amide proton chemical shifts derived from quantum mechanics
Christensen, A. S., Linnet, T. E., Borg, M., Boomsma, Wouter, Lindorff-Larsen, Kresten, Hamelryck, Thomas Wim & Jensen, Jan Halborg, 2013, In: PLoS ONE. 8, 12, 10 p., e84123.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sample planning optimization tool for conservation and population genetics (SPOTG): a software for choosing the appropriate number of markers and samples
Hoban, S., Arntzen, P., Gaggiotti, O., Bertorelle, G., Bryja, J., Fernandes, M., Frith, K., Galbusera, P., Godoy, J. A., Hauffe, H. C., Hoelzel, R., Nichols, R., Perez-Espona, S., Primmer, C., Russo, I-R. M., Segelbacher, G., Siegismund, H. R., Sihvonen, M., Sjoegren-Gulve, P., Vernesi, C. & 2 others, , 2013, In: Methods in Ecology and Evolution. 4, 3, p. 299-303 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Social insect genomes exhibit dramatic evolution in gene composition and regulation while preserving regulatory features linked to sociality
Simola, D. F., Wissler, L., Donahue, G., Waterhouse, R. M., Helmkampf, M., Roux, J., Nygaard, S., Glastad, K. M., Hagen, D. E., Viljakainen, L., Reese, J. T., Hunt, B. G., Graur, D., Elhaik, E., Kriventseva, E. V., Wen, J., Parker, B. J., Cash, E., Privman, E., Childers, C. P. & 18 others, , 2013, In: Genome Research. 23, 8, p. 1235-1247 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Microprocessor controls the activity of mammalian retrotransposons
Heras, S. R., Macias, S., Plass, M., Fernandez, N., Cano, D., Eyras, E., Garcia-Perez, J. L. & Cáceres, J. F., 2013, In: Nature Structural and Molecular Biology. 20, 10, p. 1173-1181 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Prognostic, Diagnostic, and Therapeutic Potential of Tumor Antigens
Olsen, L. R., 2013, Department of Biology, Faculty of Science, University of Copenhagen. 271 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
The confounding effect of population structure on bayesian skyline plot inferences of demographic history
Heller, Rasmus, Chikhi, L. & Siegismund, Hans Redlef, 2013, In: P L o S One. 8, 5, p. 1-10 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Understanding geographic origins and history of admixture among chimpanzees in European zoos, with implications for future breeding programmes
Hvilsom, C., Frandsen, P., Børsting, Claus, Carlsen, F., Sallé, B., Simonsen, Bo Thisted & Siegismund, Hans Redlef, 2013, In: Heredity. 110, 6, p. 586-593 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reconstructing genome evolution in historic samples of the Irish potato famine pathogen
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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True single-molecule DNA sequencing of a pleistocene horse bone
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Characterizing glucokinase variant mechanisms using a multiplexed abundance assay
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Genetic diversity of lion populations in Kenya: Evaluating past management practices and recommendations for future conservation actions
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