Computational and RNA Biology

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  1. 2011
  2. Published

    Upregulation of alpha cell glucagon-like peptide 1 (GLP-1) in Psammomys obesus--an adaptive response to hyperglycaemia?

    Hansen, A. M. K., Bödvarsdottir, T. B., Nordestgaard, D. N. E., Heller, Rasmus, Gotfredsen, C. F., Maedler, K., Fels, J., Holst, Jens Juul & Karlsen, A., 2011, In: Diabetologia. 54, 6, p. 1379-87 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    maxAlike: maximum likelihood-based sequence reconstruction with application to improved primer design for unknown sequences

    Menzel, K. P., Stadler, P. F. & Gorodkin, Jan, 2011, In: Bioinformatics. 27, 3, p. 317-325 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    miR-449 inhibits cell proliferation and is down-regulated in gastric cancer

    Bou Kheir, T., Futoma-Kazmierczak, E., Jacobsen, A., Krogh, Anders, Bardram, L., Hother, C., Grønbæk, Kirsten, Federspiel, B., Lund, Anders H. & Friis-Hansen, Lennart Jan, 2011, In: Molecular Cancer. 10, p. 1-12 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    microRNA-101 is a potent inhibitor of autophagy

    Frankel, Lisa, Wen, J., Lees, M., Høyer-Hansen, M., Farkas, T., Krogh, Anders, Jäättelä, M. & Lund, Anders H., 2011, In: E M B O Journal. 30, p. 4628-4641 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2010
  7. Published

    Differential expression of cellular microRNAs in HPV-11 transfected cells. An analysis by three different array platforms and qRT-PCR

    Dreher, A., Rossing, M., Kaczkowski, B., Nielsen, Finn Cilius & Norrild, B., 17 Dec 2010, In: Biochemical and Biophysical Research Communications. 403, 3-4, p. 357-62 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Evolutionary analysis of foot-and-mouth disease virus serotype SAT 1 isolates from East Africa suggests two independent introductions from southern Africa

    Sangula, A. K., Belsham, G., Muwanika, V. B., Heller, Rasmus, Balinda, S. N., Masembe, C. & Siegismund, Hans Redlef, 30 Nov 2010, In: BMC Evolutionary Biology. 10, 1, p. 371

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Diversity and transboundary mobility of serotype O foot-and-mouth disease virus in East Africa: implications for vaccination policies

    Balinda, S., Sangula, A. K., Heller, Rasmus, Muwanika, V. B., Belsham, G., Masembe, C. & Siegismund, Hans Redlef, 1 Oct 2010, In: Infection, Genetics and Evolution. 10, 7, p. 1058-65 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Long- and short-term selective forces on malaria parasite genomes

    Nygaard, S., Braunstein, A., Malsen, G., Van Dongen, S., Gardner, P. P., Krogh, Anders, Otto, T. D., Pain, A., Berriman, M., McAuliffe, J., Dermitzakis, E. T. & Jeffares, D. C., 1 Sep 2010, In: P L o S Genetics. 6, 9

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Molecular characterization of SAT 2 foot-and-mouth disease virus from post-outbreak slaughtered animals: implications for disease control in Uganda

    Balinda, S., Belsham, G., Masembe, C., Sangula, A. K., Siegismund, Hans Redlef & Muwanika, V. B., 1 Aug 2010, In: Epidemiology and Infection. 138, 8, p. 1204-10 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Signatures of RNA binding proteins globally coupled to effective microRNA target sites

    Jacobsen, A., Wen, J., Marks, D. S. & Krogh, Anders, 1 Aug 2010, In: Genome Research. 20, 8, p. 1010-9 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Sequencing of 50 human exomes reveals adaptation to high altitude

    Yi, X., Liang, Y., Huerta-Sanchez, E., Jin, X., Cuo, Z. X. P., Pool, J. E., Xu, X., Jiang, H., Vinckenbosch, N., Korneliussen, T. S., Zheng, H., Liu, T., He, W., Li, K., Luo, R., Nie, X., Wu, H., Zhao, M., Cao, H., Zou, J. & 50 others, Shan, Y., Li, S., Yang, Q., Asan, G., Ni, P., Tian, G., Xu, J., Liu, X., Jiang, T., Wu, R., Zhou, G., Tang, M., Qin, J., Wang, T., Feng, S., Li, G., Huasang, G., Luosang, J., Wang, W., Chen, F., Wang, Y., Zheng, X., Li, Z., Bianba, Z., Yang, G., Wang, X., Tang, S., Gao, G., Yong, C., Luo, Z., Gusang, L., Cao, Z., Zhang, Q., Ouyang, W., Ren, X., Liang, H., Zheng, H., Huang, Y., Li, J., Bolund, L., Kristiansen, Karsten, Li, Y., Zhang, Y., Zhang, X., Li, R., Li, S., Yang, H., Nielsen, Rasmus, Wang, J. & Wang, J., 2 Jul 2010, In: Science. 329, 5987, p. 75-8 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    A conceptual framework for the identification of candidate drugs and drug targets in acute promyelocytic leukemia

    Marstrand, T. T., Borup, R., Willer, A., Borregaard, N., Sandelin, Albin Gustav, Porse, Bo Torben & Theilgaard-Mønch, Kim, Jul 2010, In: Leukemia. 24, 7, p. 1265-75 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Ancient human genome sequence of an extinct Palaeo-Eskimo

    Rasmussen, M., Li, Y., Lindgreen, S., Pedersen, J. S., Albrechtsen, A., Moltke, I., Metspalu, M., Metspalu, E., Kivisild, T., Gupta, R., Bertalan, M., Nielsen, K., Gilbert, T., Wang, Y., Raghavan, M., Campos, P., Kamp, H. L. M., Wilson, A. S., Gledhill, A., Tridico, S. & 32 others, Bunce, M., Lorenzen, Eline, Binladen, J. K. M. A., Guo, X., Zhao, J., Zhang, X., Zhang, H., Li, Z., Chen, M., Orlando, L. A. A., Kristiansen, Karsten, Bak, M., Tommerup, Niels, Bendixen, C., Pierre, T. L., Grønnow, B., Meldgaard, Morten, Andreasen, C., Fedorova, S. A., Osipova, L. P., Higham, T. F. G., Ramsey, C. B., Hansen, Thomas van Overeem, Nielsen, Finn Cilius, Crawford, M. H., Brunak, Søren, Sicheritz-Pontén, T., Villems, R., Nielsen, Rasmus, Krogh, Anders, Wang, J. & Willerslev, Eske, 11 Feb 2010, In: Nature. 463, 7282, p. 757-762 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Beyond rotamers: a generative, probabilistic model of side chains in proteins

    Harder, T., Boomsma, Wouter, Paluszewski, M., Frellsen, J., Johansson, Kristoffer Enøe & Hamelryck, Thomas Wim, 1 Jan 2010, In: B M C Bioinformatics. 11, p. 306

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Calculation of accurate small angle X-ray scattering curves from coarse-grained protein models

    Stovgaard, K., Andreetta, C., Ferkinghoff-Borg, J. & Hamelryck, Thomas Wim, 1 Jan 2010, In: B M C Bioinformatics. 11, p. 429

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    3-methylcholanthrene induces differential recruitment of aryl hydrocarbon receptor to human promoters

    Pansoy, A., Ahmed, S., Valen, E., Sandelin, Albin Gustav & Matthews, J., 2010, In: Toxicological Sciences. 117, 1, p. 90-100 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    A long-standing Pleistocene refugium in southern Africa and a mosaic of refugia in East Africa: insights from mtDNA and the common eland antelope

    Lorenzen, Eline, Masembe, C., Arctander, P. & Siegismund, Hans Redlef, 2010, In: Journal of Biogeography. 37, 3, p. 571-581 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    A simple procedure for routine RNA extraction and miRNA array analyses from a single thyroid in vivo fine needle aspirate

    Rossing, M., Kaczkowski, B., Futoma-Kazmierczak, E., Glud, M., Klausen, M., Faber, Jens, Nygaard, Birte, Kiss, K., Sørensen, C. H., Nielsen, Finn Cilius, Bennedbæk, F. N. & Friis-Hansen, Lennart Jan, 2010, In: Scandinavian Journal of Clinical & Laboratory Investigation. 70, 8, p. 529-534 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Accumulation of intermediates of the carbon-phosphorus lyase pathway for phosphonate degradation in phn mutants of Escherichia coli

    Hove-Jensen, B., Rosenkrantz, T. J., Zechel, D. L. & Willemoës, Martin, 2010, In: Journal of Bacteriology. 192, 1, p. 370-374

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Antibodies against foot-and-mouth disease (FMD) virus in African buffalos (Syncerus caffer) in selected National Parks in Uganda (2001-2003)

    Ayebazibwe, C., Mwiine, F. N., Balinda, S. N., Tjørnehøj, K., Masembe, C., Muwanika, V. B., Okurut, A. R. A., Siegismund, Hans Redlef & Alexandersen, S., 2010, In: Transboundary and Emerging Diseases. 57, 4, p. 286-92 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Bioinformatical approaches to RNA structure prediction & Sequencing of an ancient human genome

    Lindgreen, S., 2010, Biologisk Institut: Museum Tusculanum. 111 p.

    Research output: Book/Report › Ph.D. thesis › Research

  24. Published

    Can small wildlife conservancies maintain genetically stable populations of large mammals? Evidence for increased genetic drift in geographically restricted populations of Cape buffalo in East Africa

    Heller, Rasmus, Okello, J. B. A. & Siegismund, Hans Redlef, 2010, In: Molecular Ecology. 19, 7, p. 1324-34 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Co-circulation of two extremely divergent serotype SAT 2 lineages in Kenya highlights challenges to foot-and-mouth disease control

    Sangula, A. K., Belsham, G. J., Muwanika, V. B., Heller, Rasmus, Balinda, S. N. & Siegismund, Hans Redlef, 2010, In: Archives of Virology. 155, 10, p. 1625-1630

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Computational immunology meets bioinformatics: the use of prediction tools for molecular binding in the simulation of the immune system

    Rapin, N. P. J., Lund, O., Bernaschi, M. & Castiglione, F., 2010, In: PloS one. 5, 4, p. e9862

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Deciphering Transcriptional Regulation: Computational Approaches

    Valen, E., 2010, Museum Tusculanum. 97 p.

    Research output: Book/Report › Ph.D. thesis › Research

  28. Published

    Design of association studies with pooled or un-pooled next-generation sequencing data

    Kim, S. Y., Li, Y., Guo, Y., Li, R., Holmkvist, J., Hansen, Torben, Pedersen, Oluf Borbye, Wang, J. & Nielsen, Rasmus, 2010, In: Genetic Epidemiology. 34, 5, p. 479-491 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Gene expression analysis of the emergence of epileptiform activity after focal injection of kainic acid into mouse hippocampus

    Motti, D., Le Duigou, C., Eugène, E., Chemaly, N., Wittner, L., Lazarevic, D., Krmac, H., Marstrand, T., Valen, E., Sanges, R., Stupka, E., Sandelin, Albin Gustav, Cherubini, E., Gustincich, S. & Miles, R., 2010, In: European Journal of Neuroscience. 32, 8, p. 1364-79 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Genetic diversity among ancient Nordic populations

    Melchior, L. C., Lynnerup, Niels, Siegismund, Hans Redlef, Kivisild, T. & Dissing, J., 2010, In: PLOS ONE. 5, 7, 9 p., e11898.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Genetic variation of inbreeding depression among floral and fitness traits in Silene nutans

    Thiele, J., Hansen, T. M., Siegismund, Hans Redlef & Hauser, T. P., 2010, In: Heredity. 104, 1, p. 52-60 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Identification of a novel locus for a USH3 like syndrome combined with congenital cataract

    Dad, S., Østergaard, Elsebet, Thykjær, T., Albrechtsen, Anders, Ravn, K. J. T., Rosenberg, T. & Møller, L. B., 2010, In: Clinical Genetics. 78, 4, p. 388-397 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    MicroRNA-145 targets YES and STAT1 in colon cancer cells

    Gregersen, Lea Haarup, Jacobsen, A. B., Frankel, Lisa, Wen, J., Krogh, Anders & Lund, Anders H., 2010, In: PLoS ONE. 5, 1, p. e8836

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    MicroRNAs and potential target interactions in psoriasis

    Zibert, J. R., Løvendorf, M. B., Litman, Thomas, Olsen, Jørgen, Kaczkowski, B. & Skov, Lone, 2010, In: Journal of Dermatological Science. 58, 3, p. 177-185 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Mocapy++ - a toolkit for inference and learning in dynamic Bayesian networks

    Paluszewski, M. & Hamelryck, Thomas Wim, 2010, In: BMC Bioinformatics. 11, Suppl 1, 6 p., 126.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Molecular signatures of thyroid follicular neoplasia

    Helweg-Larsen, R. B., Rossing, M., Henao Giraldo, R., Yamamoto, Y., Krogdahl, A., Godballe, C., Winther, Ole, Kiss, K., Christensen, L. H., Høgdall, Estrid Vilma Solyom, Bennedbæk, F. N. & Nielsen, Finn Cilius, 2010, In: Endocrine - Related Cancer. 17, 3, p. 691-708 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Multivariate Hawkes process models of the occurrence of regulatory elements

    Carstensen, L., Sandelin, Albin Gustav, Winther, Ole & Hansen, Niels Richard, 2010, In: BMC Bioinformatics. 11, p. 456

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Natural selection and the distribution of identity-by-descent in the human genome

    Albrechtsen, Anders, Moltke, Ida & Nielsen, Rasmus, 2010, In: Genetics. 186, 1, p. 295-308 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Patterns, risk factors and characteristics of reported and perceived foot-and-mouth disease (FMD) in Uganda

    Ayebazibwe, C., Tjørnehøj, K., Mwiine, F. N., Muwanika, V. B., Ademun Okurut, A. R., Siegismund, Hans Redlef & Alexandersen, S., 2010, In: Tropical Animal Health and Production. 42, 7, p. 1547-59 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Phylogenetic analyses of the polyprotein coding sequences of serotype O foot-and-mouth disease viruses in East Africa: evidence for interserotypic recombination

    Balinda, S. N., Siegismund, Hans Redlef, Muwanika, V. B., Sangula, A. K., Masembe, C., Ayebazibwe, C., Normann, P. & Belsham, G. J., 2010, In: Virology Journal. 7, p. 199

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Positive selection on apoptosis related genes

    Rodrigues da Fonseca, Rute Andreia, Kosiol, C., Vinař, T., Siepel, A. & Nielsen, Rasmus, 2010, In: FEBS Letters. 584, 3, p. 469-476 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  42. Published

    Potentials of mean force for protein structure prediction vindicated, formalized and generalized

    Hamelryck, Thomas Wim, Borg, M., Paluszewski, M., Paulsen, J., Frellsen, J., Andreetta, C., Boomsma, Wouter, Bottaro, S. & Ferkinghoff-Borg, J., 2010, In: PLoS ONE. 5, 11, 11 p., e13714.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Protein structure prediction using bee colony optimization metaheuristic

    Fonseca, R., Paluszewski, M. & Winter, Pawel, 2010, In: Journal of Mathematical Modelling and Algorithms. 9, 2, p. 181-194 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants

    Li, Y., Vinckenbosch, N., Tian, G., Huerta-Sanchez, E., Jiang, T., Jiang, H., Albrechtsen, A., Andersen, G., Cao, H., Korneliussen, T. S., Grarup, N., Guo, Y., Hellman, I., Jin, X., Li, Q., Liu, J., Liu, X., Sparsø, T., Tang, M., Wu, H. & 18 others, Wu, R., Yu, C., Zheng, H., Astrup, A., Bolund, L., Holmkvist, J., Jørgensen, T., Kristiansen, Karsten, Schmitz, O., Schwartz, Thue W., Zhang, X., Li, R., Yang, H., Wang, J., Hansen, Torben, Pedersen, Oluf Borbye, Nielsen, Rasmus & Wang, J., 2010, In: Nature Genetics. 42, 11, p. 969-72 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Sequence reconstruction and improved non-coding RNA homology search

    Menzel, K. P., 2010, Department of Basic Animal and Veterinary Sciences, University of Copenhagen. 172 p.

    Research output: Book/Report › Ph.D. thesis › Research

  46. Published

    The role of African buffalos (syncerus caffer) in the maintenance of foot-and-mouth disease in Uganda

    Ayebazibwe, C., Mwiine, F. N., Tjørnehøj, K., Balinda, S. N., Muwanika, V. B., Okurut, A. R. A., Belsham, G. J., Normann, P., Siegismund, Hans Redlef & Alexandersen, S., 2010, In: BMC Veterinary Research. 6, 13 p., 54.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    The sequence and de novo assembly of the giant panda genome

    Li, R., Fan, W., Tian, G., Zhu, H., He, L., Cai, J., Huang, Q., Cai, Q., Li, B., Bai, Y., Zhang, Z., Zhang, Y., Wang, W., Li, J., Wei, F., Li, H., Jian, M., Li, J., Zhang, Z., Nielsen, R. & 103 others, Li, D., Gu, W., Yang, Z., Xuan, Z., Ryder, O. A., Leung, F. C., Zhou, Y., Cao, J., Sun, X., Fu, Y., Fang, X., Guo, X., Wang, B., Hou, R., Shen, F., Mu, B., Ni, P., Lin, R., Qian, W., Wang, G., Yu, C., Nie, W., Wang, J., Wu, Z., Liang, H., Min, J., Wu, Q., Cheng, S., Ruan, J., Wang, M., Shi, Z., Wen, M., Liu, B., Ren, X., Zheng, H., Dong, D., Cook, K., Shan, G., Zhang, H., Kosiol, C., Xie, X., Lu, Z., Zheng, H., Li, Y., Steiner, C. C., Lam, T. T., Lin, S., Zhang, Q., Li, G., Tian, J., Gong, T., Liu, H., Zhang, D., Fang, L., Ye, C., Zhang, J., Hu, W., Xu, A., Ren, Y., Zhang, G., Bruford, M. W., Li, Q., Ma, L., Guo, Y., An, N., Hu, Y., Zheng, Y., Shi, Y., Li, Z., Liu, Q., Chen, Y., Zhao, J., Qu, N., Zhao, S., Tian, F., Wang, X., Wang, H., Xu, L., Liu, X., Vinar, T., Wang, Y., Lam, T., Yiu, S., Liu, S., Zhang, H., Li, D., Huang, Y., Wang, X., Yang, G., Jiang, Z., Wang, J., Qin, N., Li, L., Li, J., Bolund, L., Kristiansen, Karsten, Wong, G. K., Olson, M., Zhang, X., Li, S., Yang, H., Wang, J. & Wang, J., 2010, In: Nature. 463, 7279, p. 311-317 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Transcriptional regulation of gene expression clusters in motor neurons following spinal cord injury

    Ryge, J., Winther, Ole, Wienecke, Jacob, Sandelin, Albin Gustav, Westerdahl, A., Hultborn, Hans & Kiehn, O., 2010, In: BMC Genomics. 11, 1, p. 365 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    miRMaid: a unified programming interface for microRNA data resources

    Jacobsen, A., Krogh, Anders, Kauppinen, S. & Lindow, M., 2010, In: BMC Bioinformatics. 11, Suppl 1, p. 29

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. 2009
  51. Published

    MicroRNA expression analysis by LNA enhanced microarrays

    Søkilde, R., Kaczkowski, B., Barken, K. B., Mouritzen, P., Møller, Søren & Litman, Thomas, 1 Oct 2009, MicroRNA Profiling in Cancer: A Bioinformatics Perspective. Pan Stanford Publishing Pte. Ltd., p. 23-46 24 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  52. Published

    Large BRCA1 and BRCA2 genomic rearrangements in Danish high risk breast-ovarian cancer families

    Hansen, Thomas van Overeem, Jønson, L., Albrechtsen, Anders, Andersen, M. K., Ejlertsen, Bent Laursen & Nielsen, Finn Cilius, May 2009, In: Breast Cancer Research and Treatment. 115, 2, p. 315-323 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    A common Greenlandic Inuit BRCA1 RING domain founder mutation

    Hansen, T. V. O., Ejlertsen, Bent Laursen, Albrechtsen, Anders, Bergsten, E., Bjerregaard, P., Hansen, T., Myrhoj, T., Nielsen, P. B., Timmermans-Wielenga, V., Andersen, M. K., Jonson, L. & Nielsen, F. C., 2009, In: Breast Cancer Research and Treatment. 115, 1, p. 69-76 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    A fluorescent substrate for carbon-phosphorus lyase: towards the pathway for organophosphonate metabolism in bacteria

    He, S., Lou, Y., Hove-Jensen, B. & Zechel, D. L., 2009, In: Bioorganic & Medicinal Chemistry Letters. 19, 20, p. 5954-5957

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    A probabilistic approach to protein structure prediction: PHAISTOS in CASP8

    Borg, M., Boomsma, Wouter, Ferkinghoff-Borg, J., Frellsen, J., Harder, T. P., Mardia, K., Røgen, P., Stovgaard, K. & Hamelryck, Thomas Wim, 2009, LASR 2009 — Statistical Tools for Challenges in Bioinformatics. Proceedings. Gusnanto, A., Mardia, K. V. & Fallaize, C. J. (eds.). University of Leeds, p. 65-70 6 p.

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

  56. Published

    A probabilistic approach to protein structureprediction: PHAISTOS in CASP8

    Borg, M., Boomsma, Wouter, Ferkinghoff-Borg, J., Frellsen, J., Harder, T. P., Mardia, K. V., Røgen, P., Stovgaard, K. & Hamelryck, Thomas Wim, 2009, In: School of Mathematics. p. 65-70

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    A probabilistic model of RNA conformational space

    Frellsen, J., Moltke, Ida, Thiim, M., Mardia, K. V., Ferkinghoff-Borg, J. & Hamelryck, Thomas Wim, 2009, In: PLoS Computational Biology. 5, 6, p. e1000406

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads

    Rose, C. S., Grarup, Niels, Krarup, N. T., Poulsen, P., Wegner, L., Nielsen, T., Banasik, Karina, Faerch, K., Andersen, G., Albrechtsen, Anders, Borch-Johnsen, K., Clausen, J. O., Jørgensen, T., Vaag, Allan, Pedersen, Oluf Borbye & Hansen, Torben, 2009, In: Diabetologia. 52, 10, p. 2122-2129 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Adaptionism-30 years after Gould and Lewontin

    Nielsen, Rasmus, 2009, In: Evolution. 63, 10, p. 2487-90 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    An investigation of the statistical power of neutrality tests based on comparative and population genetic data

    Zhai, W., Nielsen, Rasmus & Slatkin, M., 2009, In: Molecular Biology and Evolution. 26, 2, p. 273-83 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Ancient DNA reveals late survival of mammoth and horse in interior Alaska

    Haile, James Seymour, Froese, D. G., Macphee, R. D. E., Roberts, R. G., Arnold, L. J., Reyes, A. V., Rasmussen, M., Nielsen, Rasmus, Brook, B. W., Robinson, S., Demuro, M., Gilbert, M Thomas P, Munch, K., Austin, J. J., Cooper, A., Barnes, I., Möller, P. & Willerslev, Eske, 2009, In: Proceedings of the National Academy of Science of the United States of America. 106, 52, p. 22352-7 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Applying Undertaker to quality assessment

    Archie, J. G., Paluszewski, M. & Karplus, K., 2009, In: Proteins - Structure Function and Bioinformatics. 77, S9, p. 191-195

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Biopython: freely available Python tools for computational molecular biology and bioinformatics

    Cock, P. J. A., Antao, T., Chang, J. T., Chapman, B. A., Cox, C. J., Dalke, A., Friedberg, I., Hamelryck, Thomas Wim, Kauff, F., Wilczynski, B. & de Hoon, M. J. L., 2009, In: Bioinformatics. 25, 11, p. 1422-3 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    CCHMM_PROF: a HMM-based coiled-coil predictor with evolutionary information

    Bartoli, L., Fariselli, P., Krogh, Anders & Casadio, R., 2009, In: Bioinformatics. 25, 21, p. 2757-63 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    CRISPR families of the crenarchaeal genus Sulfolobus: bidirectional transcription and dynamic properties

    Lillestøl, R. K., Shah, S. A., Brügger, K., Redder, P., Phan, Safir Hien, Christiansen, Jan & Garrett, Roger Antony, 2009, In: Molecular Microbiology. 72, 1, p. 259-272

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene-gene interaction

    Sparsø, T., Grarup, N., Andreasen, C., Albrechtsen, A., Holmkvist, J., Andersen, G., Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Madsbad, S., Hansen, T., Pedersen, O., Sparsø, T., Grarup, N., Andreasen, C., Albrechtsen, A., Holmkvist, J., Andersen, G., Jørgensen, T. & 6 others, Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Madsbad, Sten, Hansen, T. & Pedersen, O., 2009, In: Diabetologia. 52, 7, p. 1308-14 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Complete resequencing of 40 genomes reveals domestication events and genes in silkworm (Bombyx)

    Xia, Q., Guo, Y., Zhang, Z., Li, D., Xuan, Z., Li, Z., Dai, F., Li, Y., Cheng, D., Li, R., Cheng, T., Jiang, T., Becquet, C., Xu, X., Liu, C., Zha, X., Fan, W., Lin, Y., Shen, Y., Jiang, L. & 38 others, Jensen, J., Hellmann, I., Tang, S., Zhao, P., Xu, H., Yu, C., Zhang, G., Li, J., Cao, J., Liu, S., He, N., Zhou, Y., Liu, H., Zhao, J., Ye, C., Du, Z., Pan, G., Zhao, A., Shao, H., Zeng, W., Wu, P., Li, C., Pan, M., Li, J., Yin, X., Li, D., Wang, J., Zheng, H., Wang, W., Zhang, X., Li, S., Yang, H., Lu, C., Nielsen, Rasmus, Zhou, Z., Wang, J., Xiang, Z. & Wang, J., 2009, In: Science. 326, 5951, p. 433-6 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Correcting estimators of theta and Tajima's D for ascertainment biases caused by the single-nucleotide polymorphism discovery process

    Ramírez-Soriano, A. & Nielsen, Rasmus, 2009, In: Genetics. 181, 2, p. 701-10 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Darwinian and demographic forces affecting human protein coding genes.

    Nielsen, Rasmus, Hubisz, M. J., Hellmann, I., Torgerson, D., Andres, A. M., Albrechtsen, Anders, Gutenkunst, R., Adams, M. D., Cargill, M., Boyko, A., Indap, A., Bustamante, C. D. & Clark, A. G., 2009, In: Genome Research. 19, 5, p. 838-49 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Dominance of a clonal green sulfur bacterial population in a stratified lake

    Gregersen, Lea Haarup, Habicht, K. S., Peduzzi, S., Tonolla, M., Canfield, D. E., Miller, M., Cox, R. P. & Frigaard, Niels-Ulrik, 2009, In: FEMS Microbiology Ecology. 70, 1, p. 30-41 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Effect of energy metabolism on protein motility in the bacterial outer membrane

    Ryder, T. W., Xu, L., Berg-Sørensen, K., Brown, Stanley & Oddershede, L. B., 2009, In: Biophysical Journal. 97, 5, p. 1305-1312 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia

    Rung, J., Cauchi, S., Albrechtsen, A., Shen, L., Rocheleau, G., Cavalcanti-Proença, C., Bacot, F., Balkau, B., Belisle, A., Borch-Johnsen, K., Charpentier, G., Dina, C., Durand, E., Elliott, P., Hadjadj, S., Järvelin, M-R., Laitinen, J., Lauritzen, T., Marre, M., Mazur, A. & 20 others, Meyre, D., Montpetit, A., Pisinger, C., Posner, B., Poulsen, P., Pouta, A., Prentki, M., Ribel-Madsen, R., Ruokonen, A., Sandbaek, A., Serre, D., Tichet, J., Vaxillaire, M., Wojtaszewski, Jørgen F P, Vaag, Allan, Hansen, T., Polychronakos, C., Pedersen, Oluf Borbye, Froguel, P. & Sladek, R., 2009, In: Nature Genetics. 41, 10, p. 1110-1115 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    In defense of statistical methods for detecting positive selection

    Yang, Z., Nielsen, Rasmus & Goldman, N., 2009, In: Proceedings of the National Academy of Science of the United States of America. 106, 36, p. E95

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Inference of historical changes in migration rate from the lengths of migrant tracts

    Pool, J. E. & Nielsen, Rasmus, 2009, In: Genetics. 181, 2, p. 711-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Maximum likelihood estimation of weight matrices for targeted homology search

    Menzel, P., Gorodkin, Jan & Stadler, P. F., 2009, Proceedings of the German Conference on Bioinformatics 2009. Grosse, I., Neumann, S., Posch, S., Schreiber, F. & Stadler, P. (eds.). Gesellschaft für Informatik, p. 211-220 10 p. (Lecture Notes in Informatics).

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

  76. Published

    Mutational analysis of three bchH paralogs in (bacterio-)chlorophyll biosynthesis in Chlorobaculum tepidum

    Gomez Maqueo Chew, A., Frigaard, Niels-Ulrik & Bryant, D. A., 2009, In: Photosynthesis Research. 101, 1, p. 21-34 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Probabilistic models and machine learning in structural bioinformatics

    Hamelryck, Thomas Wim, 2009, In: Statistical Methods in Medical Research. 18, 5, p. 505-26 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Radiation of extant Cetaceans Driven by Restructuring of the Oceans

    Steeman, M. E., Hebsgaard, M. B., Fordyce, J., Syw, H., Rabovsky, D., Nielsen, Rasmus, Rahbek, Carsten, Glenner, Henrik, Sørensen, Martin Vinther & Willerslev, Eske, 2009, In: Systematic Biology. 58, p. 573-585 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Relatedness mapping and tracts of relatedness for genome-wide data in the presence of linkage disequilibrium

    Albrechtsen, Anders, Korneliussen, Thorfinn Sand, Moltke, Ida, van Overseem Hansen, T., Nielsen, Finn Cilius & Nielsen, Rasmus, 2009, In: Genetic Epidemiology. 33, 3, p. 266-274

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Statistical inferences in phylogeography

    Nielsen, Rasmus & Beaumont, M. A., 2009, In: Molecular Ecology. 18, 6, p. 1034-47 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Structural and kinetic studies of the allosteric transition in Sulfolobus solfataricus uracil phosphoribosyltransferase: Permanent activation by engineering of the C-terminus

    Christoffersen, S., Kadziola, Anders, Johansson, E., Rasmussen, M., Willemoës, Martin & Jensen, K. F., 2009, In: Journal of Molecular Biology. 393, 2, p. 464-477

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Structural profiles of human miRNA families from pairwise clustering

    Kaczkowski, B., Þórarinsson, E., Reiche, K., Havgaard, Jakob Hull, Stadler, P. F. & Gorodkin, Jan, 2009, In: Bioinformatics. 25, 3, p. 291-294 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Structure of PhnP: a phosphodiesterase of the carbon-phosphorous lyase pathway for phosphonate degradation

    Podzelinska, K., He, S., Wathier, M., Yakunin, A., Proudfoot, M., Hove-Jensen, B., Zechel, D. L. & Jia, Z., 2009, In: Journal of Biological Chemistry. 284, 25, p. 17216-17226

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Targets of balancing selection in the human genome

    Andrés, A. M., Hubisz, M. J., Indap, A., Torgerson, D. G., Degenhardt, J. D., Boyko, A. R., Gutenkunst, R. N., White, T. J., Green, E. D., Bustamante, C. D., Clark, A. G. & Nielsen, Rasmus, 2009, In: Molecular Biology and Evolution. 26, 12, p. 2755-64 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    The tedious task of finding homologous noncoding RNA genes

    Menzel, K. P., Gorodkin, Jan & Stadler, P. F., 2009, In: RNA: A publication of the RNA Society. 15, 12, p. 2075-2082 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Uncovering commensal bacteria-plant interaction: characterisation of bacterial endophytes and their population structures in the model plant Arabidopsis thaliana

    Paiva, D. S., Klepac-Ceraj, V., Lemon, K., Kolter, R., Frigaard, Niels-Ulrik, Gautier, L. & Sakuragi, Y., 2009.

    Research output: Contribution to conference › Conference abstract for conference › Research

  87. 2008
  88. Published

    57miRNA regulation during oncogene-induced senescence


    Christoffersen, N. R., Frankel, Lisa, Klausen, M., Jacobsen, A., Krogh, Anders & Lund, Anders H., May 2008.

    Research output: Contribution to conference › Conference abstract for conference › Research

  89. Published

    A generative, probabilistic model of local protein structure

    Boomsma, Wouter, Mardia, K. V., Taylor, C. C., Ferkinghoff-Borg, J., Krogh, Anders & Hamelryck, Thomas Wim, 2008, In: Proceedings of the National Academy of Science of the United States of America. 105, 26, p. 8932-8937 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    A genetic analysis of carbon-nanotube-binding proteins

    Brown, Stanley, Jespersen, T. S. & Nygård, Jesper, 2008, In: Small. 4, 4, p. 416-420

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Asap: a framework for over-representation statistics for transcription factor binding sites.

    Marstrand, T. T., Frellsen, J., Moltke, Ida, Thiim, M., Valen, E., Retelska, D. & Krogh, Anders, 2008, In: PLoS ONE. 3, 2, p. e1623

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes.

    Grarup, Niels, Andersen, G., Krarup, N. T., Albrechtsen, Anders, Schmitz, O., Jørgensen, T., Borch-Johnsen, K., Hansen, Torben & Pedersen, Oluf Borbye, 2008, In: Diabetes. 57, 9, p. 2534-40 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Embryonic expression of Drosophila IMP in the developing CNS and PNS

    Adolph, S. K., Delotto, R., Nielsen, Finn Cilius & Christiansen, Jan, 2008, In: Gene Expression Patterns. 9, 3, p. 138-143 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Expression, purification and preliminary diffraction studies of PhnP

    Podzelinska, K., He, S., Soares, A., Zechel, D., Hove-Jensen, B. & Jia, Z., 2008, In: Acta Crystallographica. Section F : Structural Biology and Crystallization Communications. 64, Pt 6, p. 554-7 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Fast phylogenetic DNA barcoding

    Terkelsen, K. M., Boomsma, Wouter, Willerslev, Eske & Nielsen, Rasmus, 2008, In: Philosophical Transactions of the Royal Society of London. Biological Sciences. 363, 1512, p. 3997-4002 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Genomic Insights into the Sulfur Metabolism of Phototrophic Green Sulfur Bacteria

    Frigaard, Niels-Ulrik & Bryant, D. A., 2008, In: Advances in Photosynthesis and Respiration. 27, p. 337-355 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Genomic and Evolutionary Perspectives on Sulfur Metabolism in Green Sulfur Bacteria

    Frigaard, Niels-Ulrik & Bryant, D. A., 2008, Microbial Sulfur Metabolism. Springer, p. 60-76 16 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  98. Published

    Hidden Markov models for prediction of protein features.

    Bystroff, C. & Krogh, Anders, 2008, In: Methods in Molecular Biology. 413, p. 173-98 25 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Identification of the bchP gene, encoding geranylgeranyl reductase in Chlorobaculum tepidum

    Gomez Maqueo Chew, A., Frigaard, Niels-Ulrik & Bryant, D. A., 2008, In: Journal of Bacteriology. 190, 2, p. 747-749 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation

    Sparsø, T., Andersen, G., Albrechtsen, Anders, Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Wasson, J., Permutt, M. A., Glaser, B., Madsbad, Sten, Pedersen, Oluf Borbye & Hansen, Torben, 2008, In: Diabetologia. 51, 9, p. 1646-52 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  101. Published

    In vivo and in vitro studies of the neuronal RNA-binding protein Drosophila IMP

    Adolph, S. K., 2008, Biologisk Institut: Museum Tusculanum. 144 p.

    Research output: Book/Report › Ph.D. thesis › Research

  102. Published

    Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation

    Andreasen, C. H., Stender-Petersen, K. L., Mogensen, M. S., Torekov, Signe Sørensen, Wegner, L., Andersen, G., Nielsen, A. L., Albrechtsen, Anders, Borch-Johnsen, K., Rasmussen, S. S., Clausen, J. O., Sandbaek, A., Lauritzen, T., Hansen, L., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, T., 2008, In: Diabetes. 57, 1, p. 95-101 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  103. Published

    Mechanism of dTTP inhibition of the bifunctional dCTP deaminase:dUTPase encoded by Mycobacterium tuberculosis

    Helt, S. S., Thymark, M., Harris, P., Aagaard, C., Dietrich, J., Larsen, Sine & Willemoës, Martin, 2008, In: Journal of Molecular Biology. 376, 2, p. 554-69 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  104. Published

    Protein Decoy Generation Using Branch and Bound with Efficient Bounding

    Paluszewski, M. & Winter, Pawel, 2008, Algorithms in Bioinformatics: 8th International Workshop, WABI 2008, Karlsruhe, Germany, September 15-19, 2008, Proceedings. Crandall, K. A. & Lagergren, J. (eds.). Springer, p. 382-393 12 p. (Lecture Notes in Computer Science : Lecture Notes in Bioinformatics; No. 5251).

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

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